Excitatory amino acid receptor agonist Excitatory amino acid reuptake inhibitor N-methyl-D-aspartate receptor antagonist MeSH ... amino+acid+antagonists at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Amino acids, Excitatory ... An excitatory amino acid receptor antagonist, or glutamate receptor antagonist, is a chemical substance which antagonizes one ... amino acid receptor antagonists, All stub articles, Pharmacology stubs). ...

Muir KW, Lees KR (March 1995). "Clinical experience with excitatory amino acid antagonist drugs". Stroke. 26 (3): 503-13. doi: ... 7-Dichlorokynurenic acid. Kynurenic acid (a naturally occurring antagonist). TK-40 (competitive antagonist at the GluN1 glycine ... van den Bos R, Charria Ortiz GA, Cools AR (June 1992). "Injections of the NMDA-antagonist D-2-amino-7-phosphonoheptanoic acid ( ... AP5 (APV, R-2-amino-5-phosphonopentanoate). AP7 (2-amino-7-phosphonoheptanoic acid). CGP-37849 CPPene (3-[(R)-2- ...

As NMDA receptor antagonists, dextrorphan and dextromethorphan inhibit the excitatory amino acid and neurotransmitter glutamate ... Muir, KW; Lees, KR (1995). "Clinical experience with excitatory amino acid antagonist drugs". Stroke. 26 (3): 503-513. doi: ... Helmy, Sanaa A. K.; Bali, Ayham (March 2001). "The Effect of the Preemptive Use of the NMDA Receptor Antagonist ... Kristensen, JD; Svensson, B; Gordh Jr., T (1992). "The NMDA-receptor antagonist CPP abolishes neurogenic 'wind-up pain' after ...

"Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists". J. Neural Transm. 72 (3): 191-200. doi: ... NMDA receptor antagonists, Phosphonic acids, Alpha-Amino acids). ... The optically pure D-(−)-2-amino-7-phosphonoheptanoic acid [D- ... These excitatory glutamate receptors work with the inhibitory GABA receptors to achieve equilibrium in the DPAG of the brain. ... Both AP-7 and D-AP7 function as potent, specific antagonists of the NMDA receptor. APV (drug) Meldrum B, Millan M, Patel S, de ...

They include excitatory amino acid receptor agonists and excitatory amino acid receptor antagonists. Christensen, Inge T.; ... Excitatory amino acid receptor ligands are ligands of excitatory amino acid receptors (EAARs), also known as glutamate ... "Excitatory amino acid receptor ligands. Synthesis and biological activity of 3-isoxazolol amino acids structurally related to ... v t e v t e (Orphaned articles from July 2019, All orphaned articles, Excitatory amino acid receptor ligands, All stub articles ...

"Antinociceptive actions of different classes of excitatory amino acid receptor antagonists in mice". European Journal of ... 3-Amino-1-hydroxy-pyrrolidin-2-one is a molecule used in scientific research as a glycine receptor and NMDA receptor antagonist ... Bonta IL, De Vos CJ, Grijsen H, Hillen FC, Noach EL, Sim AW (Nov 1971). "1-Hydroxy-3-amino-pyrrolidone-2(HA-966): a new GABA- ... S-(−)-HA-966 has been described as a "γ-hydroxybutyric acid (GHB)-like agent" and a "potent y-butyrolactone-like sedative", but ...

Rogawski MA (September 1993). "Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3- ... Diphenidine and related diarylethylamines have been studied in vitro as treatments for neurotoxic injury and are antagonists of ...

Examples include excitatory amino acid receptor agonists, excitatory amino acid receptor antagonists, and excitatory amino acid ... is a chemical that directly modulates the excitatory amino acid (glutamate/aspartate) system in the body or brain. ...

October 1993). "The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy". Epilepsy Research. 16 ... Carboxylic acids, NMDA receptor antagonists, Phosphonic acids, Piperazines). ... piperazine-2-carboxylic acid (D-CPP) and D(-)(E)-4-(3-phosphonoprop-2-enyl) piperazine-2-carboxylic acid (D-CPPene) in a rodent ... NMDA receptor antagonist Lowe DA, Neijt HC, Aebischer B (June 1990). "D-CPP-ene (SDZ EAA 494), a potent and competitive N- ...

July 1988). "CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist". The ... Carboxylic acids, Dissociative drugs, NMDA receptor antagonists, Phosphonic acids, Piperidines). ... receptor antagonists in pigeons: cross-tolerance between PCP-like compounds and competitive NMDA antagonists". The Journal of ... Selfotel (CGS-19755) is a drug which acts as a competitive NMDA antagonist, directly competing with glutamate for binding to ...

Both dextrorphan and ketamine are non-competitive NMDA receptor antagonists and have shown to reduce excitatory amino acid- ... Acupuncture Alpha-lipoic acid Herbs Amino acids Lifestyle and home remedies Take care of your feet, especially if you have ...

It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid ... AMPA receptor antagonists, Aromatic acids, Hydroxy acids, Kainate receptor antagonists, Nicotinic antagonists, NMDA receptor ... Kynurenic acid (KYNA or KYN) is a product of the normal metabolism of amino acid L-tryptophan. It has been shown that kynurenic ... Kynurenic acid acts in the brain as a glycine-site NMDAr antagonist, key in glutamatergic neurotransmission system, which is ...

... reuptake inhibitor Glycine reuptake inhibitor Excitatory amino acid receptor agonist Excitatory amino acid receptor antagonist ... An excitatory amino acid reuptake inhibitor (EAARI) is a type of drug which inhibits the reuptake of the excitatory ... Media related to Excitatory amino acid reuptake inhibitors at Wikimedia Commons v t e (Commons category link is on Wikidata, ... Excitatory amino acid reuptake inhibitors, All stub articles, Pharmacology stubs). ...

... excitatory amino acid reuptake inhibitors, beta-2 antagonists (bronchodilators), haemostatic and antifibrinolytic drugs. ... Willis C, Lybrand S, Bellamy N (2004). "Excitatory amino acid inhibitors for traumatic brain injury". The Cochrane Database of ... "Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in ... Tranexamic acid within three hours of a head injury decreases the risk of death. Certain facilities are equipped to handle TBI ...

... and tetra-substituted guanidines and their use as excitatory amino acid antagonists", published 1991-09-05, assigned to ... Schäbitz WR, Li F, Fisher M (July 2000). "The N-methyl-D-aspartate antagonist CNS 1102 protects cerebral gray and white matter ... Hoyte L, Barber PA, Buchan AM, Hill MD (March 2004). "The rise and fall of NMDA antagonists for ischemic stroke". Current ... Muir KW, Grosset DG, Gamzu E, Lees KR (July 1994). "Pharmacological effects of the non-competitive NMDA antagonist CNS 1102 in ...

Excitatory amino acid reuptake inhibitors, Experimental drugs, NMDA receptor antagonists, Prodrugs). ... 4-Chlorokynurenine penetrates the blood-brain barrier via the large neutral amino acid transporter 1. In the central nervous ... is an orally active small molecule prodrug of 7-chlorokynurenic acid, a NMDA receptor antagonist. It was investigated as a ... Most of its therapeutic potential is believed to occur via 7-chlorokynurenic acid which inhibits the glycine co-agonist site of ...

Excitatory amino acids, such as glutamate and aspartate, are released in toxic amounts when the brain is deprived of blood and ... Dissociative Dextromethorphan (DXM) Ketamine Phencyclidine (PCP) Glutamate Ibotenic acid NMDA receptor NMDA antagonists Olney's ... Nicotinic antagonists, NMDA receptor antagonists, Diarylethylamines, Dissociative drugs, Dibenzocycloheptenes, Designer drugs) ... NMDA antagonists like dizocilpine have been shown in animal models to attenuate the hearing loss caused by aminoglycosides It ...

... was found to increase levels of the excitatory amino acid neurotransmitters glutamate and aspartate, as well as ... Dawson LA, Nguyen HQ, Li P (November 2001). "The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory ... Dawson LA, Nguyen HQ, Li P (May 2000). "In vivo effects of the 5-HT(6) antagonist SB-271046 on striatal and frontal cortex ... It was one of the first selective 5-HT6 receptor antagonists to be discovered, and was found through high-throughput screening ...

Excitatory amino acid reuptake inhibitors, Kainate receptor antagonists, NMDA receptor agonists, Non-proteinogenic amino acids ... derived from the related proteinogenic L-amino acid glutamic acid. Theanine is an analog of this amino acid, and its primary ... is an amino acid analogue of the proteinogenic amino acids L-glutamate and L-glutamine and is found primarily in particular ... Alpha-Amino acids, AMPA receptor antagonists, Anxiolytics, Carboxamides, ...

GABA receptor antagonist Glutamate receptor: see also Excitatory amino acid receptor agonist, Excitatory amino acid receptor ... antagonist, Ionotropic glutamate receptor, Ampakine, NMDA receptor antagonist Nicotinic receptor: see also Nicotinic agonist, ... see also 5-HT3 antagonist, GABAA receptor: see also GABA receptor agonist, ...

... α-Decarboxylation of excitatory amino acids can produce derivatives with inhibitory effects. Indeed, unlike quisqualic acid, ... Mg2+ and DL-AP5, NMDA receptor blockers, CNQX, an antagonist of both the AMPA and kainate receptors, and 2-hydroxysaclofen, a ... a novel gamma-aminobutyric acid (GABA) related depressant amino acid". The Journal of Pharmacy and Pharmacology. 30 (6): 364-7 ... Quisqualic acid Muscimol Evans RH, Francis AA, Hunt K, Martin MR, Watkins JC (June 1978). "Quisqualamine, ...

... acid Kainic acid N-Methyl-D-aspartic acid Quisqualic acid Excitatory amino acid receptor antagonist Excitatory amino acid ... Amino acids, Excitatory amino acid receptor agonists, All stub articles, Nervous system drug stubs). ... An excitatory amino acid receptor agonist, or glutamate receptor agonist, is a chemical substance which agonizes one or more of ... reuptake inhibitor Excitatory+amino+acid+agonists at the U.S. National Library of Medicine Medical Subject Headings (MeSH) MeSH ...

Zhang W, Han XY, Wong SM, Takeuchi H (January 1997). "Pharmacologic characteristics of excitatory gamma-amino-butyric acid ( ... GABAA receptor antagonists, Glycine receptor antagonists, 1-Piperazinyl compounds, Triazoles, All stub articles, Nervous system ... Takeuchi H (September 1992). "Sensitivities of Achatina giant neurones to putative amino acid neurotransmitters". Comparative ... Pitrazepin is a competitive GABAA and glycine receptor antagonist. It has been used to study insect and snail nervous systems ...

Shirasaki Y, Sugimura M, Sato T (September 2010). "Bromocriptine, an ergot alkaloid, inhibits excitatory amino acid release ... As an antagonist of the serotonin 5-HT2B receptor, bromocriptine has not been associated with cardiac valvulopathy. This is in ... Agonist and antagonist properties at subtypes of dopamine D(2)-like receptor and alpha(1)/alpha(2)-adrenoceptor". J Pharmacol ... Agonist and antagonist properties at serotonin, 5-HT(1) and 5-HT(2), receptor subtypes". J Pharmacol Exp Ther. 303 (2): 815-22 ...

This phenomenon might be attributed to the activation of excitatory amino acid receptors which subsequently provoke an ... AMPA receptor antagonists, Kainate receptor antagonists, NMDA receptor antagonists, Nitro compounds, Quinoxalines, Quinones, ... Dopaminergic antagonists often do not prevent the acquisition of a conditioned place preference for cocaine, a common measure ... Conversely, the dopaminergic antagonist fluphenazine did not alter cocaine-induced place preference, possibly due to ...

Excitatory Amino Acids include Glutamate, whereas inhibitory Amino Acids include GABA and Glycine. Additionally, catecholamines ... Conversely, antagonists bind to a receptor and elicit no cellular change. Naloxone, an antagonist of the opioid receptors, ... Although aNMDA receptor antagonists and anti-inflammatory drugs were tested in a clinical environment, more promising clinical ... In animal models, NMDA antagonists increase glutamate release in the prefrontal cortex. It is postulated that this is a ...

Collingridge GL, Kehl SJ, McLennan H (January 1983). "Excitatory amino acids in synaptic transmission in the Schaffer ... an antagonist to the NMDA receptor, which prevented LTP in this pathway. Conversely, LTP in the mossy fiber pathway is NMDA ... Robert Malenka, a prominent LTP researcher, has suggested that LTP may even occur at all excitatory synapses in the mammalian ... Lømo T (1966). "Frequency potentiation of excitatory synaptic activity in the dentate area of the hippocampal formation". Acta ...

This compound is also routinely used to isolate glutamatergic (excitatory amino acid) receptor function. The action of ... "Advantages of an antagonist: bicuculline and other GABA antagonists". British Journal of Pharmacology. 169 (2): 328-336. doi: ... GABAA receptor antagonists, Glycine receptor antagonists, Convulsants, 3-(5,6,7,8-tetrahydro-(1,3)dioxolo(4,5-g)isoquinolin-5- ... Bicuculline is a phthalide-isoquinoline compound that is a light-sensitive competitive antagonist of GABAA receptors. It was ...

"Kainic Acid - an overview , ScienceDirect Topics". www.sciencedirect.com. Retrieved 2022-01-15. "GABA-A Receptor Antagonists - ... Mares P, Folbergrová J, Kubová H (2004). "Excitatory aminoacids and epileptic seizures in immature brain". Physiological ... AMPA Domoic acid Kainic acid NMDA Quinolinic acid Quisqualic acid Tetrazolylglycine Acetylcholine receptor agonists are drugs ... 3-Mercaptopropionic acid Allylglycine Glycine receptor antagonists are drugs which inactivates the glycine receptors. ...

"The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid". Eur. J. ... 1996). "Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and ... 1995). "Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes ... of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist ...