LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and ... Drug-Induced Liver Disease. pp. 605-619. doi:10.1016/B978-0-12-387817-5.00033-9. ISBN 9780123878175. The frequency of liver ... Malešević N, Bokan G, Đajić V (2020). "Flutamide Induced Liver Injury in Female Patients". European Journal of Medical and ... Drug-Induced Liver Disease. CRC Press. pp. 618-619. ISBN 978-0-203-90912-6. Thole Z, Manso G, Salgueiro E, Revuelta P, Hidalgo ...

Fisher, Kurt; Vuppalanchi, Raj; Saxena, Romil (2015). "Drug-Induced Liver Injury". Archives of Pathology & Laboratory Medicine ... Liver injuries are rarely serious, though most injuries to the liver are concomitant with other injuries, particularly to the ... Injuries to the nervous system include brain injury, spinal cord injury, and nerve injury. Trauma to the brain causes traumatic ... Liver injury is the most common type of organ damage in cases of abdominal trauma. The liver's size and location in the body ...

Pessayre D, Mansouri A, Berson A, Fromenty B (2010). "Mitochondrial involvement in drug-induced liver injury". Adverse Drug ... Labbe G, Pessayre D, Fromenty B (August 2008). "Drug-induced liver injury through mitochondrial dysfunction: mechanisms and ... 1994). "[Hepatitis induced by alpidem (Ananxyl). Four cases, one of them fatal]" [Hepatitis induced by alpidem (Ananxyl). Four ... Rarely, alpidem can cause serious liver toxicity, including liver failure and death. Alpidem is a nonbenzodiazepine of the ...

Andrade, Raúl J; Robles, Mercedes; Ulzurrun, Eugenia; Lucena, M Isabel (2009). "Drug-induced liver injury: insights from ... "Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease". Liver International. 34 (7): e171-e179. ... In the case of overdoses, the storage of GSH will not be enough for NAPQI detoxication, thereby resulting in acute liver injury ... Hepatotoxicity indicates the drug's toxicity to liver. Paracetamol (acetaminophen, APAP) is converted into the hepatotoxic ...

Diagnosis of HIV drug caused drug induced liver injury (DILI): The most important way to figure out whether the ART drug causes ... Drug-induced liver injury is a common cause of prolonged hospital stays for people with HIV, and in more severe reactions can ... Other reported risk factors for drug induced liver injury are female gender, young age, and high CD4+ count of >200 cells/mm3. ... Studies have reported that efavirenz is a potential agent that caused drug induced liver injury in HIV-positive patients taking ...

"No clinically significant androgenic effects were observed." In early 2020 a single case report of drug-induced liver injury ... "Drug-Induced Liver Injury by Selective Androgenic Receptor Modulators". Hepatology Communications. 4 (3): 450-452. doi:10.1002/ ... Drugs missing an ATC code, Drugs with no legal status, Articles containing unverified chemical infoboxes, Chloroarenes, ... v t e (Articles with short description, Short description matches Wikidata, Infobox drug articles with non-default infobox ...

WHO Drug Information. 33 (1). hdl:10665/330896. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. ... drug interaction by inducing CYP enzymes. Vutrisiran is not expected to modulate drug transporter activities. "Amvuttra- ... "Vutrisiran Orphan Drug Designations and Approvals". U.S. Food and Drug Administration (FDA). 25 May 2018. Archived from the ... The U.S. Food and Drug Administration (FDA) granted the application for vutrisiran orphan drug designation. On 21 July 2022, ...

ISBN 978-0-07-142280-2. "Meprobamate". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. U.S. National ... Meprobamate was one of the first drugs to be widely advertised to the general public, with user Milton Berle promoting the drug ... BEHAVIOR' DRUGS NOW ENVISIONED; Aldous Huxley Predicts They Will Bring Re-Examining of Ethics and Religion". The New York Times ... Frank Berger was working in a laboratory of a British drug company, looking for a preservative for penicillin, when he noticed ...

"Meclizine". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD): National Institute of ... "Prediction of drug-induced catalepsy based on dopamine D1, D2, and muscarinic acetylcholine receptor occupancies". Drug ... Wishard D. "Drug card for Meclizine". DrugBank. Canada: University of Alberta. Retrieved 7 November 2010. "Meclizine". Drug ... "Meclizine Use During Pregnancy". Drugs.com. Retrieved 3 March 2019. Fischer J, Ganellin CR (2006). Analogue-based Drug ...

"Nizatidine". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. NCBI Bookshelf. 25 January 2018. PMID ... "Nizatidine: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Retrieved 20 March 2020. Fischer J, Ganellin CR (2006 ... Food and Drug Administration (FDA). However, a year later, they sold rights of the Axid Oral Solution (including the issued ... Analogue-based Drug Discovery. John Wiley & Sons. p. 44. ISBN 9783527607495. " ...

"Drug Record: Sevoflurane". Livertox: Clinical and Research Information on Drug-Induced Liver Injury. 2 July 2014. PMID 31643176 ... It is now available as a generic drug. Sevoflurane is a greenhouse gas. The twenty-year global-warming potential, GWP(20), for ... Sevoflurane is a potent vasodilator, as such it induces a dose dependent reduction in blood pressure and cardiac output. It is ... Haria M, Bryson HM, Goa KL, Patel SS (August 1996). "Erratum". Drugs. 52 (2): 253. doi:10.1007/bf03257493. Wallin RF, Regan BM ...

"Onasemnogene Abeparvovec". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. NCBI Bookshelf. 20 August ... Drugs with non-standard legal status, Infobox drug articles with non-default infobox title, Infobox drug articles without a ... Drug discovery, Experimental drugs, Gene therapy, Novartis brands, Orphan drugs, Spinal muscular atrophy). ... In Japan, the drug was made available through the public health care system on 20 May 2020, making it the most expensive drug ...

"Drug Record - Amoxicillin-Clavulanate". LiverTox - Clinical and Research Information on Drug-Induced Liver Injury. Retrieved ... Clavulanic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as ... After several attempts, Beecham finally filed for US patent protection for the drug in 1981, and U.S. Patents 4,525,352, ... Clavulanic acid was discovered around 1974-75 by British scientists working at the drug company Beecham from the bacteria ...

"Green Tea". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institutes of Health. 2012. ... ingestion of large amounts of green tea have been implicated in cases of clinically apparent acute liver injury, including ... Excessive consumption of green tea extract has been associated with hepatotoxicity and liver failure. In 2018, a scientific ... However, Green tea interferes with the chemotherapy drug bortezomib (Velcade) and other boronic acid-based proteasome ...

"Thioridazine". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and ... Thioridazine has been correlated to rare instances of clinically apparent acute cholestatic liver injury. Thioridazine has the ... Thioridazine (Mellaril or Melleril) is a first generation antipsychotic drug belonging to the phenothiazine drug group and was ... The drug has been successfully used in the treatment of granulomatous amoebic encephalitis in conjunction with more ...

"Dicloxacillin". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and ... doi:10.1007/978-1-4614-1400-1_3. ISBN 978-1-4614-1399-8. Greenwood D (2008). "4. Wonder Drugs". Antimicrobial Drugs: Chronicle ... "Floxacillin". Drug Information Portal. U.S. National Library of Medicine. Portal: Medicine (Use dmy dates from June 2022, ... Other side effects may include muscle or joint pains, shortness of breath, and liver problems. It appears to be safe during ...

Tujios S, Fontana RJ (April 2011). "Mechanisms of drug-induced liver injury: from bedside to bench". Nature Reviews. ... Antiviral drugs, Nucleosides, Organofluorides, Organoiodides, Withdrawn drugs, Tetrahydrofurans, Diols, Pyrimidinediones, ... In a 1993 clinical study at the NIH, unexpected toxicity led to the death of 5 out of 15 patients from liver failure alongside ... v t e (Articles with short description, Short description matches Wikidata, Drugs not assigned an ATC code, Articles with ...

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and ... Cupp, M. J. (1999). "Herbal remedies: Adverse effects and drug interactions". American Family Physician. 59 (5): 1239-1245. ... either alone or in interaction with other herbs or drugs. Non-inclusion of an herb in this list does not imply that it is free ... "Hepatotoxicity Induced by 'the 3Ks': Kava, Kratom and Khat". International Journal of Molecular Sciences. 17 (4): 580. doi: ...

Clinical and Research Information on Drug-Induced Liver Injury. 1 (1). 2018-01-01. PMID 31644158. NBK548851. Ma TG, Ling YH, ... Clinical and Research Information on Drug-Induced Liver Injury [Internet]. PMID 31643481. Retrieved 2021-01-27 - via NCBI ... In rare cases, repeated exposure to halothane in adults was noted to result in severe liver injury. This occurred in about one ... Isoflurane is essentially not metabolized and reports of associated liver injury are quite rare. Small amounts of ...

"Eugenol (Clove Oil)". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes ... Clove oil is toxic in anything other than small therapeutic doses, and several cases of acute liver and kidney damage have been ... Food portal Medicine portal "Clove". Drugs.com. 3 July 2020. Retrieved 27 September 2020. "Clove". MedlinePlus, National ...

Clinical and Research Information on Drug-Induced Liver Injury. 30 May 2014. PMID 31643719. NBK548400. Retrieved 19 March 2020 ... "Meticorten: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). "Delta-Cortef: FDA-Approved Drugs". U.S. Food and ... Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no ... "Prednisone Information". Drugs.com. "Prednisone". MedlinePlus Drug Information. Wolkowitz OM, Lupien SJ, Bigler ED (June 2007 ...

"Pexidartinib". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda, MD: National Institute of ... "Drug Approval Package: Turalio". U.S. Food and Drug Administration (FDA). 22 July 2019. Retrieved 17 March 2020. "New Drug ... "Microglial Magic: Drug Wipes Them Out, New Set Appears". Alzforum. 18 April 2014. Retrieved 19 March 2020. "Drug Trials ... The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. The approval of pexidartinib was ...

"LiverTox: Clinical and Research Information on Drug-Induced Liver Injury". United States National Library of Medicine. 2012. ... There have been several reports and small case series of acute liver injury with jaundice arising 1 to 3 months after starting ... "Protective effects of the aqueous extract of Scutellaria baicalensis against acrolein-induced oxidative stress in cultured ...

"Methocarbamol". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and ... Although unlikely, it is impossible to rule out that methocarbamol may cause mild liver injury with use. Skeletal muscle ... "Methocarbamol". Drugs.com. Retrieved 12 May 2018. "New Drugs and Indications Reviewed at the May 2003 DEC Meeting" (PDF). ESI ... Drugs with unknown mechanisms of action, Muscle relaxants, Secondary alcohols, Veterinary drugs, Glycerols, Methoxy compounds, ...

"Imipenem-Cilastatin". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. 17 January 2017. PMID 31644018 ... Common adverse drug reactions are nausea and vomiting. People who are allergic to penicillin and other β-lactam antibiotics ... "Imipenem". Drug Information Portal. U.S. National Library of Medicine. Portal: Medicine (CS1: long volume value, CS1 errors: ... Carbapenems are highly resistant to the β-lactamase enzymes produced by many multiple drug-resistant Gram-negative bacteria, ...

96-. ISBN 978-81-322-1686-5. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD ... There is no evidence to indicate that there is cross sensitivity to liver injury among the various GnRH analogues despite their ... Single instances of clinically apparent liver injury have been reported with some GnRH agonists (histrelin, goserelin), but the ... Generally this induced and reversible hypogonadism is the therapeutic goal. During the flare, peak levels of testosterone occur ...

"Cholestyramine". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National ... Interactions with these drugs have been noted: Digitalis Estrogens and progestins Oral diabetes drugs Penicillin G ... procedure in patients taking leflunomide or teriflunomide to aid drug elimination in the case of drug discontinuation due to ... Other drugs should be taken at least one hour before or four to six hours after colestyramine to reduce possible interference ...

"Diphenhydramine". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National ... It has been shown to be a potentiator of analgesia induced by morphine, but not by endogenous opioids, in rats. The drug has ... There were no documented cases of clinically apparent acute liver injury caused by normal doses of diphenhydramine. The most ... As diphenhydramine is extensively metabolized by the liver, caution should be exercised when giving the drug to individuals ...

"Sulindac". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National ... In October 2020, the U.S. Food and Drug Administration (FDA) required the drug label to be updated for all nonsteroidal anti- ... Bartlett sustained severe injuries including the loss of over 60% of her surface skin and permanent near-blindness. The case ... Imbaral (not to be confused with mebaral) is another name for this drug. Its name is derived from sul(finyl)+ ind(ene)+ ac(etic ...

"LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]". nih.gov. National Institute of Health. ... When taken by mouth, pennyroyal oil is highly toxic and has been linked to several instances of toxic liver injury and death. " ...