... "smart drug delivery" originated. Encapsulated within the idea of smart drug delivery is the use of gated delivery systems. ... Gated drug delivery systems are a recent innovation in the field of drug delivery and pose as a promising candidate for future ... These smart drug delivery systems are able to delivery the drug with minimal leakage, can be actively or passively targeted to ... The history of gated drug delivery systems starts in the mid-1960s when the concept of zero order controlled drug delivery was ...

The exact biological mechanisms by which dextran-based drug delivery systems act on the drug target must be elucidated as well ... Microspheres composed of dextran have several advantages as a drug delivery system including controlled drug release, localized ... These drug-polymer complexes have advantages such as longer drug half-life and improved targeted drug delivery. Dextran ... Dextran-based drug delivery systems have an enormous potential for clinical use in the treatment of a variety of disease states ...

... the development of stimuli-responsive drug delivery systems has created the ability to tune drug delivery systems to achieve ... Redox-responsive drug delivery systems are also used in the delivery of DNA and siRNA for gene therapy.. Redox-responsive drug ... pH-responsive drug delivery systems are particularly suitable for the design of chemotherapeutic delivery systems due to the ... As a result, the drug is released from the system. pH responsive drug delivery systems are typically synthesized from pH- ...

A self-microemulsifying drug delivery system (SMEDDS) is a drug delivery system that uses a microemulsion achieved by chemical ... "Self-emulsifying drug delivery systems in oral (poly)peptide drug delivery". Expert Opin Drug Deliv. 12 (11): 1703-1716. doi: ... "Self-nano-emulsifying drug delivery systems: an update of the biopharmaceutical aspects". Expert Opinion on Drug Delivery. 12 ( ... Attama AA; Nkemnele MO (November 2005). "In vitro evaluation of drug release from self micro-emulsifying drug delivery systems ...

The conventional drug delivery system is the absorption of the drug across a biological membrane, whereas the targeted release ... Antibody-drug conjugate Retrometabolic drug design Magnetic drug delivery PH-responsive tumor-targeted drug delivery Muller, R ... Targeted drug delivery systems have been developed to optimize regenerative techniques. The system is based on a method that ... The goal of a targeted drug delivery system is to prolong, localize, target and have a protected drug interaction with the ...

... drug-targeting Drug delivery to the brain Drug carrier Magnetic drug delivery Neural drug delivery systems Retrometabolic drug ... design Self-microemulsifying drug delivery system Tecrea Thin film drug delivery "Drug Delivery Systems (definition)". www. ... Jain, Kewal K. (2020), Jain, Kewal K. (ed.), "An Overview of Drug Delivery Systems", Drug Delivery Systems, Methods in ... Drug delivery systems have been around for many years, but there are a few recent applications of drug delivery that warrant 1 ...

"External stimuli-responsive drug delivery systems". Drug Delivery Devices and Therapeutic Systems: 267-288. doi:10.1016/b978-0- ... "Toward closed-loop drug delivery: Integrating Wearable Technologies with Transdermal Drug Delivery Systems". Advanced Drug ... This method of drug delivery falls in the category of stimuli-responsive drug delivery systems which include pH, temperature, ... Stretch-triggered drug delivery has been applied to the cardiovascular system through the use of drug-loaded hydrogels that ...

Several gene therapy drugs used in hydrogel-based drug delivery systems include CRISPR/Cas9, siRNA, and other RNA-based drugs. ... These hydrogel-based systems are also paired with chemotherapy treatments. Cancer drugs used in this drug delivery platforms ... "Injectable thermoresponsive hydrogels as drug delivery system for the treatment of central nervous system disorders: A review ... "State-of-the-art materials for ultrasound-triggered drug delivery". Advanced Drug Delivery Reviews. 72: 3-14. doi:10.1016/j. ...

Kreuter, Jörg (2001). "Nanoparticulate systems for brain delivery of drugs". Advanced Drug Delivery Reviews. 47 (1): 65-81. doi ... "Drug delivery to the central nervous system by polymeric nanoparticles: What do we know?". Advanced Drug Delivery Reviews. 71: ... PBCA, chitosan, and PLGA nanoparticles were used as delivery systems for these drugs. Overall, the results from each drug ... Metal nanoparticles are promising as carriers for drug delivery to the brain. Common metals used for nanoparticle drug delivery ...

... systems refer to drug delivery systems utilizing coiled-coil motifs capable of delivering disease- ... "Coiled coil-based therapeutics and drug delivery systems". Advanced Drug Delivery Reviews. 170: 26-43. doi:10.1016/j.addr. ... Coiled-coils can be used to create nanoparticle drug delivery systems capable of delivering drugs or other biological molecules ... Coiled-coil polymer hybrid drug delivery systems can also be used in drug-free macromolecular therapeutic (DFMT) applications, ...

"Intracochlear drug delivery systems: a novel approach whose time has come". Expert Opinion on Drug Delivery. 15 (4): 319-324. ... "Non-dermal applications of microneedle drug delivery systems". Drug Delivery and Translational Research. 12 (1): 67-78. doi: ... Kim YC, Park JH, Prausnitz MR (November 2012). "Microneedles for drug and vaccine delivery". Advanced Drug Delivery Reviews. 64 ... "Rapidly dissolving polymeric microneedles for minimally invasive intraocular drug delivery". Drug Delivery and Translational ...

... aids in wound dressing Another application of bioprinting in the field of drug delivery is non-hydrogel drug delivery systems. ... resulting in a hydrogel that leverages the delivery of drugs, protects drugs with encapsulation, and allows for tunable drug ... These systems allow localized delivery of personalized drugs. The implants are printed in the same additive manufacturing ... Whether 3D or 4D, the application of bioprinting to the development of drug delivery systems allows for biocompatible, ...

Drug delivery is a process of administering therapeutics to treat human diseases. The first drug delivery system often dates ... can help evaluate efficacy and safety of such delivery systems. Nanoparticles are drug delivery systems ranging from 1-1000 nm ... Drugs can be loaded in dendrimers through formulation and nanoconstruct. For drug delivery systems to bypass the blood brain ... Nasal cavity is a slightly acidic environment with enzymes which can alter degradation of drug delivery systems. The delivery ...

Jeong, Woo Yeup; Kwon, Mina; Choi, Hye Eun; Kim, Ki Su (December 2021). "Recent advances in transdermal drug delivery systems: ... Laser-assisted drug delivery (LADD) is a drug delivery technique commonly used in the dermatology field that involves lasers. ... "Laser-assisted drug delivery: mode of action and use in daily clinical practice: Laser-assisted drug delivery". JDDG: Journal ... "Fractional CO 2 laser-assisted drug delivery: FRACTIONAL CO 2 LASER-ASSISTED DRUG DELIVERY". Lasers in Surgery and Medicine. 42 ...

... triggering structural and chemical changes within the drug delivery system. This form of targeted drug delivery is to localize ... Besides the drugs, conducting clinical trials can also be very expensive. When drug delivery systems tend to have high ... pH-triggered drug delivery systems are able to control the pharmacokinetics and the biodistribution of the drugs enclosed ... Additionally, drug-loaded particles within the hydrogel have been proposed as dual-stimuli responsive drug delivery systems ...

"Development of a mucoadhesive nanoparticulate drug delivery system for a targeted drug release in the bladder". International ... Intravesical drug delivery is the delivery of medications directly into the bladder by urinary catheter. This method of drug ... The delivery of drugs directly to the bladder is a large improvement over systemic delivery which only allows a small fraction ... Delivering drugs directly to the target bladder site allows for maximizing drug delivery while minimizing systemic effects. ...

Abdus, S., Y. Sultana, and M. Aqil, Liposomal Drug Delivery Systems: An Update Review. Current Drug Delivery, 2007. 4(4): p. ... Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled ... Ma, Y., R.J.M. Nolte, and J.J.L.M. Cornelissen, Virus-based nanocarriers for drug delivery. Advanced Drug Delivery Reviews, ... Current nanoparticle drug delivery systems can be cataloged based on their platform composition into several groups: polymeric ...

Ghosal, Kajal; Ranjan, Alok; Bhowmik, Benoy Brata (2014-07-01). "A novel vaginal drug delivery system: anti-HIV bioadhesive ... Advanced Drug Delivery Reviews. Relevance of Mucus to Advanced Drug Delivery. 11 (3): 385-401. doi:10.1016/0169-409X(93)90017-X ... "Vaginal drug delivery for the localised treatment of cervical cancer". Drug Delivery and Translational Research. 7 (6): 817-828 ... "Vaginal drug delivery approaches for localized management of cervical cancer". Advanced Drug Delivery Reviews. 174: 114-126. ...

Burgess, A., & Hynynen, K. (2016). Microbubble-Assisted Ultrasound for Drug Delivery in the Brain and Central Nervous System. ... of drugs from accessing the central nervous system, so FUS has the potential to address a major challenge in intracranial drug ... "Concurrent blood-brain barrier opening and local drug delivery using drug-carrying microbubbles and focused ultrasound for ... "Concurrent blood-brain barrier opening and local drug delivery using drug-carrying microbubbles and focused ultrasound for ...

The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the ... Gupta, BP; Thakur, N; Jain, NP; Banweer, J; Jain, S (2010). "Osmotically controlled drug delivery system with associated drugs ... Theeuwes, F; Yum, SI; Haak, R; Wong, P (1991). "Systems for triggered, pulsed, and programmed drug delivery". Annals of the New ... Using an osmotic pump to deliver drugs has additional inherent advantages regarding control over drug delivery rates. This ...

Nervous System Drug Delivery. Academic Press. pp. 3-20. doi:10.1016/b978-0-12-813997-4.00001-3. ISBN 978-0-12-813997-4. S2CID ... February 2016). "Systems Proteomics View of the Endogenous Human Claudin Protein Family". Journal of Proteome Research. 15 (2 ... A recent review discusses evidence regarding the structure and function of claudin family proteins using a systems approach to ... Hou J (2019-01-01). "Chapter 7 - Paracellular Channel in Organ System". In Hou J (ed.). The Paracellular Channel. Academic ...

Nervous System Drug Delivery. Academic Press. pp. 3-20. doi:10.1016/b978-0-12-813997-4.00001-3. ISBN 978-0-12-813997-4. S2CID ... Within the Sertoli cells of the male reproductive system, JAM-3 interacts with JAM-2 to influence the polarity of both round ... 3 has been shown to be a primary regulator of the development of spermatids as well as the rest of the male reproductive system ...

His research is focused on the design and physicochemical characterisation of advanced polymeric drug delivery systems for ... "Mucoadhesive drug delivery systems". Journal of Pharmacy and Bioallied Sciences. 3 (1): 89-100. doi:10.4103/0975-7406.76478. ...

The first modern remote drug-delivery system was invented by scientists at the University of Georgia in the 1950s, and was the ... "Remote Drug Delivery Systems". Journal of Zoo and Wildlife Medicine. 23 (2): 159-180. JSTOR 20095205. С. Успенский. ... If you shot somebody who was big or had drugs in their system, it might not do anything." says Newett, of the Justice ... "Drugged beverages are so much easier to conceal," explains Dr. Theodore Davantzis. The only person who has been suspected to ...

... in drug delivery systems, the mucus layer must be penetrated in order to effectively transport micro- or nanosized drug ... "Nasal mucoadhesive drug delivery: Background, applications, trends and future perspectives". Advanced Drug Delivery Reviews. 57 ... Boddupalli, Bindu M.; Mohammed, Zulkar N.K.; Nath, Ravinder A.; Banji, David (2010). "Mucoadhesive drug delivery system: An ... Bernkop-Schnürch, A; Dünnhaupt, S (August 2012). "Chitosan-based drug delivery systems". Eur J Pharm Biopharm. 81 (3): 463-469 ...

Researchers have devised ways to use smart polymers to control the release of drugs until the delivery system has reached the ... Liechty, W. B., Kryscio, D. R., Slaughter, B. V., & Peppas, N. A. (2012). Polymers for drug delivery systems. HHS Author ... Many creative approaches to targeted drug delivery systems that self-regulate based on their unique cellular surroundings, are ... Bordbar-Khiabani A, Gasik M. "Smart hydrogels for advanced drug delivery systems". International Journal of Molecular Sciences ...

Robb Pharmaceutical Systems for Drug Delivery, David Jones; Chien YW. 2nd ed. New York: Marcel Dekker, Inc; 1993. Novel drug ... meaning delivery of the drug settles to a constant rate. This is crucial in drug delivery and is used in cases such as the ... Medical Uses: Permeation can also be seen in the medical field in drug delivery. Drug patches made up of polymer material ... delivery systems. O.V. Malykh, A.Yu. Golub, V.V. Teplyakov, "Polymeric membrane materials: New aspects of empirical approaches ...

Therefore, it has been used for many medical applications such as in treatment for tissue infection, drug delivery systems, and ... Chitosan as drug delivery: Chitosan is used mainly with drug targeting because it has potential to improve drug absorption and ... Bernkop-Schnürch, Andreas; Dünnhaupt, Sarah (2012). "Chitosan-based drug delivery systems". European Journal of Pharmaceutics ... Additionally, there have been developments with alginate as a drug delivery medium, as drug release rate can easily be ...

Neurotoxicity concern about the brain targeting delivery systems". In Gao H, Gao X (eds.). Brain Targeted Drug Delivery System ... FUCCI is a system that takes advantage of cell cycle phase-specific expression of proteins and their degradation by the ... Hydroxyurea (HU) is a small molecule drug that inhibits the enzyme ribonucleotide reductase (RNR), preventing the catalysis of ... Xu K, Schwarz PM, Ludueña RF (Feb 2002). "Interaction of nocodazole with tubulin isotypes". Drug Development Research. 55 (2): ...

Gupta S, Dhanda S, Sandhir R (2019). "Anatomy and physiology of blood-brain barrier". Brain Targeted Drug Delivery System. ... Mechanisms for drug targeting in the brain involve going either "through" or "behind" the BBB. Modalities for drug delivery to ... to overcome this barrier some peptides able to naturally cross the BBB have been widely investigated as a drug delivery system ... Silva GA (December 2008). "Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS". BMC ...