Dihydropteridine reductase deficiency
... (DHPRD) is a genetic disorder affecting the tetrahydrobiopterin (BH4) synthesis pathway, ...
6,7-dihydropteridine reductase
NADH-dihydropteridine reductase, NADPH-dihydropteridine reductase, NADPH-specific dihydropteridine reductase, dihydropteridine ... reduced nicotinamide adenine dinucleotide), reductase, dihydropteridine reductase, dihydropteridine reductase (NADH), and 5,6,7 ... In enzymology, 6,7-dihydropteridine reductase (EC 1.5.1.34, also Dihydrobiopterin reductase) is an enzyme that catalyzes the ... "Dihydropteridine reductase. Investigation of the specificity for quinoid dihydropteridine and the inhibition by 2,4- ...
QDPR
... (quinoid dihydropteridine reductase) is a human gene that produces the enzyme quinoid dihydropteridine reductase. This ... "Human dihydropteridine reductase: characterisation of a cDNA clone and its use in analysis of patients with dihydropteridine ... 1998). "Dihydropteridine reductase deficiency: physical structure of the QDPR gene, identification of two new mutations and ... Brown RM, Dahl HH (1987). "Localization of the human dihydropteridine reductase gene to band p15.3 of chromosome 4 by in situ ...
Tetrahydrobiopterin deficiency
Ponzone A, Spada M, Ferraris S, Dianzani I, de Sanctis L (2004). "Dihydropteridine reductase deficiency in man: from biology to ... deficient dihydrobiopterin reductase renders any PAH produced unable to use phenylalanine to produce tyrosine. ... Tetrahydrobiopterin deficiency can be caused by a deficiency of the enzyme dihydrobiopterin reductase (DHPR), whose activity is ...
Sepiapterin reductase
1998). "Dihydropteridine reductase deficiency localized to the central nervous system". J. Inherit. Metab. Dis. 21 (4): 433-434 ... 1999). "Variant of dihydropteridine reductase deficiency without hyperphenylalaninaemia: effect of oral phenylalanine loading ... Sepiapterin reductase is an enzyme that in humans is encoded by the SPR gene. Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ ... 2006). "The sepiapterin reductase gene region reveals association in the PARK3 locus: analysis of familial and sporadic ...
Tetrahydrobiopterin
Chemically, its structure is that of a (dihydropteridine reductase) reduced pteridine derivative (quinonoid dihydrobiopterin).[ ... Because of its mechanism, tetrahydrobiopterin might interact with dihydrofolate reductase inhibitors like methotrexate and ... and sepiapterin reductase (SR). BH4 can be oxidized by one or two electron reactions, to generate BH4 or BH3 radical and BH2, ...
Tyrosine hydroxylase
Then, the NAD(P)H dependent enzyme dihydropteridine reductase (DHPR) converts q-BH2 back to BH4. Each of the four subunits in ...
Adiponectin
August 1992). "Characterization and nucleotide binding properties of a mutant dihydropteridine reductase containing an ...
Queuine
BH2 must then be converted back to BH4 by the enzyme dihydropteridine reductase before it can be used again. Queuine depletion ...
DHPR
... may refer to: 6,7-dihydropteridine reductase, an enzyme dihydropyridine receptor, a calcium channel This disambiguation ...
Nitroreductase
7-dihydropteridine reductase) (EC 1.5.1.34) and NADH dehydrogenase (EC 1.6.99.3). A number of these proteins are described as ... Cob(II)yrinic acid a,c-diamide reductase InterPro: IPR012825 IYD; Hecht HJ, Erdmann H, Park HJ, Sprinzl M, Schmid RD (December ...
Microcephaly
Single gene defects Smith-Lemli-Opitz syndrome Seckel syndrome Cornelia de Lange syndrome Dihydropteridine reductase deficiency ...
International Working Group on Neurotransmitter Related Disorders
... dihydropteridine reductase, sepiapterin reductase, folate receptor alpha, dihydrofolate reductase, 3-phosphoglycerate ...
Hyperphenylalaninemia
... enzymatic activity but have a deficiency in dihydropteridine reductase (DHPR), an enzyme required for the regeneration of ...
List of diseases (H)
Hyperphenylalaninemia due to pterin-4-alpha-carbin Hyperphenylalaninemia due to dihydropteridine reductase deficiency ...
Chromosome 4
... quinoid dihydropteridine reductase RBM47: RNA binding motif protein 47 RG9MTD2: encoding protein RNA (guanine-9-) ...
List of diseases (D)
... lung disease DiGeorge syndrome Digestive duplication Digitorenocerebral syndrome Digoxin toxicity Dihydropteridine reductase ...
Dopamine-responsive dystonia
6-Pyruvoyltetrahydropterin synthase deficiency Sepiapterin reductase deficiency Dihydropteridine reductase deficiency The ... and sepiapterin reductase". Ibnosina Journal of Medicine and Biomedical Sciences. 13 (1): 44. doi:10.4103/ijmbs.ijmbs_23_21. ...
List of MeSH codes (D08)
... testosterone 5-alpha-Reductase MeSH D08.811.682.662.162 - dihydropteridine reductase MeSH D08.811.682.662.171 - FMN reductase ... gmp reductase MeSH D08.811.682.655.500 - nitrate reductases MeSH D08.811.682.655.500.124 - nitrate reductase MeSH D08.811. ... nitrite reductases MeSH D08.811.682.655.750.249 - ferredoxin-nitrite reductase MeSH D08.811.682.655.750.500 - nitrite reductase ... ferredoxin-nadp reductase MeSH D08.811.682.667.092 - glutathione reductase MeSH D08.811.682.667.124 - hydrogensulfite reductase ...
List of EC numbers (EC 1)
... vomilenine reductase EC 1.5.1.33: pteridine reductase EC 1.5.1.34: 6,7-dihydropteridine reductase EC 1.5.1.35: identical to EC ... flavin reductase (NADH) EC 1.5.1.37: FAD reductase (NADH) EC 1.5.1.38: FMN reductase (NADPH) EC 1.5.1.39: FMN reductase (NAD(P) ... zeatin reductase EC 1.3.1.70: Δ14-sterol reductase EC 1.3.1.71: Δ24(241)-sterol reductase EC 1.3.1.72: Δ24-sterol reductase EC ... nitrite reductase (NAD(P)H) EC 1.7.1.5: hyponitrite reductase EC 1.7.1.6: azobenzene reductase EC 1.7.1.7: GMP reductase EC 1.7 ...