Deoxyadenosine
... is the DNA nucleoside A, which pairs with deoxythymidine (T) in double-stranded DNA. In absence of adenosine ... Deoxyadenosine (symbol dA or dAdo) is a deoxyribonucleoside. It is a derivative of the nucleoside adenosine, differing from the ... deoxyadenosine) Severe combined immunodeficiency Griffiths, Anthony J. F.; Wessler, Susan R.; Carroll, Sean B.; Doebly, John ( ...
Deoxyadenosine monophosphate
... (dAMP), also known as deoxyadenylic acid or deoxyadenylate in its conjugate acid and conjugate ... "Showing metabocard for Deoxyadenosine monophosphate (HMDB0000905)". Human Metabolome Database, HMDB. 5.0. v t e (Articles ... Deoxyadenosine monophosphate is abbreviated dAMP. It is a monomer used in DNA. Nucleic acid DNA metabolism Cofactor Guanosine ...
Deoxyadenosine triphosphate
... (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA ... Deoxyadenosine triphosphate is produced from DNA by the action of nuclease P1, adenylate kinase, and pyruvate kinase. High ... Cohen A, Hirschhorn R, Horowitz SD, Rubinstein A, Polmar SH, Hong R, Martin DW (January 1978). "Deoxyadenosine triphosphate as ... Ullman B, Gudas LJ, Cohen A, Martin DW (June 1978). "Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma ...
Deoxyadenosine diphosphate
... is a nucleoside diphosphate. It is related to the common nucleic acid ATP, or adenosine triphosphate ... Deoxyadenosine diphosphate is abbreviated dADP. Cofactor Guanosine Cyclic adenosine monophosphate dADP - Compound Summary, ...
Deoxyadenosine kinase
In enzymology, a deoxyadenosine kinase (EC 2.7.1.76) is an enzyme that catalyzes the chemical reaction ATP + deoxyadenosine ... The systematic name of this enzyme class is ATP:deoxyadenosine 5'-phosphotransferase. This enzyme is also called purine- ... Krygier V, Momparler RL (1968). "The regulatory properties of deoxyadenosine kinase". Biochim. Biophys. Acta. 161 (2): 578-80. ... the two substrates of this enzyme are ATP and deoxyadenosine, whereas its two products are ADP and dAMP. This enzyme belongs to ...
5'-deoxyadenosine deaminase
... (also known as "DadD") is an enzyme that catalyzes the conversion of 5′-deoxyadenosine to 5′- ... 5'-deoxyadenosine deaminase catalyses the salvage pathway of 5'-deoxyadenosine to 5'-deoxyinosine following the reaction ... The solved crystal structure of 5'-deoxyadenosine deaminase can be found in the SMR database here. The DadD enzyme is unique in ... The EC number of 5'-deoxyadenosine deaminase is EC:3.5.4.41. The Enzyme Commission Number is a system of classifying enzymes ...
Cordycepin
... , or 3'-deoxyadenosine, is a derivative of the nucleoside adenosine, differing from the latter by the replacement of ... 2'-Deoxyadenosine Cunningham, K. G.; Manson, W.; Spring, F. S. & Hutchinson, S. A. (1950). "Cordycepin, a Metabolic Product ... Deoxyadenosine (Cordycepin) Produces a Rapid and Robust Antidepressant Effect via Enhancing Prefrontal AMPA Receptor Signaling ...
Cladribine
Chemically, it mimics the nucleoside deoxyadenosine. However, unlike deoxyadenosine, it is relatively resistant to breakdown by ... As a purine analogue, cladribine (2-chloro-2'-deoxyadenosine [2-CdA]) is taken up into rapidly proliferating cells, including B ... Cladribine (2-chloro-2'-deoxyadenosine [2-CdA]) is a purine analogue that selectively targets and suppresses lymphocytes ...
Deoxycytidine kinase
Hurley MC, Palella TD, Fox IH (December 1983). "Human placental deoxyadenosine and deoxyguanosine phosphorylating activity". ... specifically deoxyadenosine (dA) and deoxyguanosine (dG), and convert them into their monophosphate forms. There has been ...
Peliosis hepatis
ISBN 978-0-7216-4563-6. Gushiken FC (2000). "Peliosis hepatis after treatment with 2-chloro-3'-deoxyadenosine". South. Med. J. ...
Adenosine kinase
Fox IH, Kelley WN (1978). "The role of adenosine and 2'-deoxyadenosine in mammalian cells". Annual Review of Biochemistry. 47: ...
Adenine
Adenosine is adenine reacted with ribose, as used in RNA and ATP; deoxyadenosine is adenine attached to deoxyribose, as used to ... Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose. It forms ...
Phage-assisted continuous evolution
PACE was also used to create a more catalytically active deoxyadenosine deaminase. Deoxyadenosine deaminase is used in base ... Using this system, they evolved a deoxyadenosine deaminase with 590 fold activity compared to wild type. Esvelt, K.; Carlson, J ...
Lipoyl synthase
The three products are N6-(lipoyl)lysine, L-methionine, and 5'-deoxyadenosine. Below displays the overall reaction catalyzed by ...
Oligonucleotide synthesis
... alkyl amines using N-isobutyryl protected deoxyadenosine phosphoramidite". Tetrahedron Lett. 38 (18): 3123. doi:10.1016/S0040- ...
Thymidine kinase
June 2012). "Deoxyribonucleoside kinases in two aquatic bacteria with high specificity for thymidine and deoxyadenosine". FEMS ...
Nucleoside phosphoramidite
McMinn, D. (1997). "Synthesis of oligonucleotides containing 3'-alkyl amines using N-isobutyryl protected deoxyadenosine ...
Glutathione S-transferase
"Deoxyribonucleoside kinases in two aquatic bacteria with high specificity for thymidine and deoxyadenosine". FEMS Microbiology ...
Xanthosine phosphorylase
This protein can degrade all purine nucleosides (including xanthosine) except adenosine, deoxyadenosine, hypoxanthine ... deoxyadenosine, or hypoxanthine arabinoside. Although this reaction is reversible in vitro, phosphorolysis is dominant in vivo ...
5'-nucleotidase
... association with adenosine deaminase deficiency and nonassociation with deoxyadenosine toxicity". Clinical Immunology and ...
Thymidine
Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used ...
Islatravir
... (4′-ethynyl-2-fluoro-2′-deoxyadenosine, EFdA, or MK-8591) is an investigational drug for the treatment of HIV ... Deoxyadenosine) Provides Rapid Suppression of HIV Viremia in Humanized Mice and Favorable Pharmacokinetic Properties in Mice ... deoxyadenosine (EFdA)". Proceedings of the National Academy of Sciences. 113 (33): 9274-9279. doi:10.1073/pnas.1605223113. PMC ... deoxyadenosine (EFdA) Inhibits HIV-1 Reverse Transcriptase with Multiple Mechanisms". Journal of Biological Chemistry. 289 (35 ...
Glossary of genetics (0-L)
deoxyadenosine One of the four standard deoxyribonucleosides used in DNA molecules, consisting of an adenine base with its N9 ... Adenine bonded to deoxyribose is known as deoxyadenosine, which is the version used in DNA. adenosine diphosphate (ADP) ...
Adenosine deaminase
The two isoforms regulate the ratio of adenosine to deoxyadenosine potentiating the killing of parasites. ADA2 is found ...
Deoxyinosine monophosphate
It can be formed by the deamination of the purine base in deoxyadenosine monophosphate (dAMP). The enzyme deoxyribonucleoside ...
Ribose-seq
"Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine". ...
S-adenosyl-L-homocysteine hydrolase
Hershfield, M S (1979). "In vivo inactivation of erythrocyte S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine in adenosine ...
Charles Flexner
... deoxyadenosine-5'-triphosphate concentrations in HIV-infected patients. AIDS Research and Human Retroviruses, 23(11), 1360-1365 ...
Didanosine
The preparation of 2',3'-dideoxyadenosine, 2',5'-dideoxyadenosine, and 2',3',5'-trideoxyadenosine from 2'-deoxyadenosine". ...
Morpheein
... deoxyadenosine". Archives of Biochemistry and Biophysics. 233 (2): 785-95. doi:10.1016/0003-9861(84)90507-1. PMID 6091559. ...