"Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum". Phytochemistry. 26 (10): 2699-2704. doi: ... In enzymology, a cysteine synthase (EC 2.5.1.47) is an enzyme that catalyzes the chemical reaction O3-acetyl-L-serine + ... cysteine synthetase, S-sulfocysteine synthase, 3-O-acetyl-L-serine:hydrogen-sulfide, and 2-amino-2-carboxyethyltransferase. ... "Enzymatic-synthesis of the neuroexcitatory amino-acid quisqualic by cysteine synthase". Phytochemistry. 25 (12): 2759-2763. doi ...

Ramamurthy V, Swann SL, Spedaliere CJ, Mueller EG (October 1999). "Role of cysteine residues in pseudouridine synthases of ... tRNA pseudouridine32 synthase (EC 5.4.99.28, RluA, pseudouridine synthase RluA, Pus9p, Rib2/Pus8p) is an enzyme with systematic ... TRNA+pseudouridine32+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC 5.4. ... Wrzesinski J, Nurse K, Bakin A, Lane BG, Ofengand J (June 1995). "A dual-specificity pseudouridine synthase: an Escherichia ...

"Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum". Phytochemistry. 26 (10): 2699-2704. doi: ... In enzymology, an uracilylalanine synthase (EC 2.5.1.53) is an enzyme that catalyzes the chemical reaction O3-acetyl-L-serine ... Ahmmad MAS; Maskall CS; Brown EG (1984). "Partial-purification and properties of willardiine and synthase activity from Pisum ... Other names in common use include O3-acetyl-L-serine acetate-lyase (adding uracil), isowillardiine synthase, willardiine ...

S-carboxymethyl-L-cysteine-forming). This enzyme is also called S-carboxymethyl-L-cysteine synthase. It employs one cofactor, ... Kumagai H, Suzuki H, Shigematsu H, Tuchikura T (1989). "S-Carboxymethylcysteine synthase from Escherichia coli". Agric. Biol. ... The enzyme S-carboxymethylcysteine synthase (EC 4.5.1.5) catalyzes the reaction 3-chloro-L-alanine + thioglycolate ⇌ {\ ... displaystyle \rightleftharpoons } S-carboxymethyl-L-cysteine + chloride This enzyme belongs to the family of lyases, ...

This conversion requires the enzyme glutamate-cysteine ligase (GCL, glutamate cysteine synthase). This reaction is the rate- ... It plays a role in the storage of cysteine. Glutathione enhances the function of citrulline as part of the nitric oxide cycle. ... It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and cysteine. The ... Ha SB, Smith AP, Howden R, Dietrich WM, Bugg S, O'Connell MJ, Goldsbrough PB, Cobbett CS (June 1999). "Phytochelatin synthase ...

Therefore, cysteine synthase is purified from the leaves of Quisqualis indica var. villosa, showing two forms of this enzyme. ... "Enzymatic synthesis of the neuroexcitatory amino acid quisqualic acid by cysteine synthase". Phytochemistry. 25 (12): 2759-2763 ... Both isolated isoenzymes catalyse the formation of cysteine from O-acetyl-L-serine and hydrogen sulphide, but only one of them ...

This is a byproduct of the metabolism of cysteine by cystathionine-b-synthase. Like with NO, inhalation of H2S has been found ... Nitric Oxide (NO) is a byproduct of the metabolism of arginine to citrulline by NO synthase. This gas is available in all cells ...

The enzyme cysteine synthase, using sulfide sources, converts this ester into cysteine, releasing acetate. The cysteine ... Cysteine is encoded by the codons UGU and UGC. Like other amino acids (not as a residue of a protein), cysteine exists as a ... l-Cysteine is also used as a processing aid for baking. In the field of personal care, cysteine is used for permanent-wave ... N-Acetyl-l-cysteine is a derivative of cysteine wherein an acetyl group is attached to the nitrogen atom. This compound is sold ...

Cysteine synthase, for example, catalyzes the formation of acetic acids and cysteine from O3-acetyl-L-serine and hydrogen ... elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2". PLOS ONE. 8 (11): e80135. ... Selenocysteine synthase, which was first added to the classification system in 1999, converts seryl-tRNA(Sec UCA) into ... An example of a prominent glycosyltransferase is lactose synthase which is a dimer possessing two protein subunits. Its primary ...

Hondorp, Elise R.; Matthews, Rowena G. (May 2009). "Oxidation of cysteine 645 of cobalamin-independent methionine synthase ... Multiple sources: Drennan, C. L.; Matthews, R. G.; Ludwig, M. L. (December 1994). "Cobalamin-dependent methionine synthase: the ... methionine synthase, a B-12 dependent enzyme in humans, and methylenetetrahydrofolate reductase. Her collaboration with ... cobalamin-dependent methionine synthase. A love affair with vitamins (2009) Cobalamin- and corrinoid-dependent enzymes ...

Pyridoxal phosphate (PLP) utilizing enzymes such as cysteine synthase have also been said to resemble a P-loop. The A-loop ( ... The conserved sequence of this motif is C-x(5)-R-[ST], where C and R denote cysteine and arginine residues respectively. ... Major lineages include: RecA and rotor ATP synthase / ATPases (α and β subunits). Nucleic acid-dependent ATPases: helicases, ... and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold". The ...

"Organisation of the yeast ATP synthase F(0):a study based on cysteine mutants, thiol modification and cross-linking reagents". ... "The molecular neighborhood of subunit 8 of yeast mitochondrial F1F0-ATP synthase probed by cysteine scanning mutagenesis and ... a type of naturally-derived antibiotic that is able to inhibit the Fo unit of ATP synthase. The Fo region of ATP synthase is a ... that encodes a subunit of mitochondrial ATP synthase, ATP synthase Fo subunit 8 (or subunit A6L). This subunit belongs to the ...

Codexis). Another example is the possibility of using the promiscuous activities of cysteine synthase (cysM) towards ... promiscuity can be decreased as was the case of γ-humulene synthase (a sesquiterpene synthase) from Abies grandis that is known ... including overexpression of the large component of a synthase in the absence of the amine transferase subunit), pathway bypass ... "Semisynthetic production of unnatural L-alpha-amino acids by metabolic engineering of the cysteine-biosynthetic pathway". ...

... cysteine synthase, L-serine hydro-lyase (adding homocysteine), methylcysteine synthase, serine sulfhydrase, and serine ... The lack of CBS in these tissues implies that these tissues are unable to synthesize cysteine and that cysteine must be ... Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. It catalyzes ... Methylcysteine synthase was assigned the EC number EC 4.2.1.23 in 1961. A side-reaction of CBS caused this. The EC number EC ...

Transfer of a cysteine synthase from a bacterium into phytophagous mites and Lepidoptera allowing the detoxification of ... Ginolhac, A., Jarrin, C., Robe, P., Perrière, G., Vogel, T. M., Simonet, P., & Nalin, R. (2005). Type I polyketide synthases ... Polyketide synthases (PKSs) and biosynthetic gene clusters provide modular organizations of associated genes making these ...

... a putative cysteine synthase and sul, a putative dihydropteroate synthase. In Listeria monocytogenes four additional copies of ...

The enzyme L-3-cyanoalanine synthase (EC 4.4.1.9) catalyzes the chemical reaction L-cysteine + hydrogen cyanide ⇌ {\ ... β-cyano-L-alanine synthase, and L-cysteine hydrogen-sulfide-lyase (adding HCN). This enzyme participates in cyanoamino acid ... The systematic name of this enzyme class is L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide L-3-cyanoalanine-forming ... Purification and properties of the β-cyanolanine synthase of blue lupine". J. Biol. Chem. 244 (10): 2632-40. doi:10.1016/S0021- ...

"Evidence for identity of beta-pyrazolealanine synthase with cysteine synthase in watermelon: formation of beta-pyrazole-alanine ... Other names in common use include beta-(1-pyrazolyl)alanine synthase, beta-pyrazolealanine synthase, beta-pyrazolylalanine ... synthase (acetylserine), O3-acetyl-L-serine acetate-lyase (adding pyrazole), BPA-synthase, pyrazolealanine synthase, ... by cloned cysteine synthase in vitro and in vivo". Biochem. Biophys. Res. Commun. 197 (3): 1111-7. doi:10.1006/bbrc.1993.2592. ...

It is synthesized by the addition and oxidation of cysteine to histidine by 5-histidylcysteine sulfoxide synthase, followed by ...

... encoded cysteine synthase. and the metZ or metY -encoded homocysteine synthase, Weekley, C. M. and Harris, H. H. (2013). "Which ... Cystathionine γ-synthase (metB) which joins an activated homoserine ester (acetyl or succinyl) with cysteine to form ... with homocysteine to form cystathionine Not Cystathionine β-synthase which is a PLP enzyme type II cysteine biosynthesis from ... In Klebsiella pneumoniae the cystathionine β-synthase is encoded by mtcB, while the γ-lyase is encoded by mtcC. Humans are ...

... deoxyhypusine synthase EC 2.5.1.47: cysteine synthase EC 2.5.1.48: cystathionine γ-synthase EC 2.5.1.49: O-acetylhomoserine ... 2-ethylmalate synthase EC 2.3.3.7: 3-ethylmalate synthase EC 2.3.3.8: ATP citrate synthase EC 2.3.3.9: malate synthase EC 2.3. ... synthase EC 2.3.3.2: decylcitrate synthase EC 2.3.3.3: citrate (Re)-synthase EC 2.3.3.4: decylhomocitrate synthase EC 2.3.3.5: ... synthase EC 2.4.1.12: cellulose synthase (UDP-forming) EC 2.4.1.13: sucrose synthase EC 2.4.1.14: sucrose-phosphate synthase EC ...

Small amounts of biosynthetic enzymes L-cysteine synthase and acetyltransferase were detected in L. jordanis and L. pneumophila ...

"Solvent-Accessible Cysteines in Human Cystathionine β-Synthase: Crucial Role of Cysteine 431 inS-Adenosyl-l-methionine Binding ... An example of such a conformational disease is ALAD porphyria, which results from a mutation of porphobilinogen synthase that ... The one protein that is established to function as a morpheein is porphobilinogen synthase, though there are suggestions ... An inhibitor of porphobilinogen synthase with this mechanism of action has been documented. The morpheein model of allosteric ...

Identification of an essential active site cysteine". The Journal of Biological Chemistry. 270 (40): 23450-5. doi:10.1074/jbc. ... GMP synthase forms a tetramer in an open box shape, which is a dimer of dimers. The R interfaces are held together with a ... GMP synthase is the second step in the generation of GMP from IMP; the first step occurs when IMP dehydrogenase generates XMP, ... GMP synthase is also involved in amino acid metabolism because it generates L-glutamate from L-glutamine. This enzyme is widely ...

... lyase it is associated as enzyme complex named cysteine synthase. The formation of cysteine is the direct coupling step between ... The thiol groups of the cysteine residues in proteins can be oxidized resulting in disulfide bridges with other cysteine side ... Sulfite is further reduced to sulfide by sulfite reductase, which is then incorporated into cysteine by enzyme. Cysteine, once ... which are synthesized enzymatically by a constitutive phytochelatin synthase. The number of γ-glutamyl-cysteine residues in the ...

... cystathionine synthase, cystathionine synthetase, homoserine transsuccinylase, 4-O-succinyl-L-homoserine:L-cysteine, and S-(3- ... Cystathionine gamma-synthase from plants uses L-homoserine phosphate instead. This enzyme belongs to the family of transferases ... The systematic name of this enzyme class is O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase. Other ... In enzymology, a cystathionine gamma-synthase (EC 2.5.1.48) is an enzyme that catalyzes the formation of cystathionine from ...

The characteristic reaction of β-ketoacyl-ACP synthase III is malonyl-ACP + acetyl-CoA => acetoacyl-ACP + CO2 + CoA. Cysteine, ... the two most common 3-ketoacyl-ACP synthase I and synthase II. 3-Ketoacyl-ACP synthase I (E.C. 2.3.1.41) is involved in the ... The dominant enzyme in the KS1 family is 3-ketoacyl-ACP synthase III (KAS III), also known as 3-oxoacyl-ACP synthase III and β- ... Chalcone synthase (E.C. 2.3.1.74), also known as naringenin-chalcone synthase, is responsible for the reaction: 3 malonyl-CoA ...

"Mechanisms of mitochondrial holocytochrome c synthase and the key roles played by cysteines and histidine of the heme ... "Entrez Gene: HCCS holocytochrome c synthase (cytochrome c heme-lyase)". "Search results < Expression Atlas < EMBL-EBI". Babbitt ... 2006). "Mutations of the mitochondrial holocytochrome c-type synthase in X-linked dominant microphthalmia with linear skin ... "Mutations of the mitochondrial holocytochrome c-type synthase in X-linked dominant microphthalmia with linear skin defects ...

Mammals biosynthesize the amino acid cysteine via homocysteine. Cystathionine β-synthase catalyses the condensation of ... In the body, homocysteine can be recycled into methionine or converted into cysteine with the aid of vitamin B6, B9, and B12. ... It is a homologue of the amino acid cysteine, differing by an additional methylene bridge (-CH2-). It is biosynthesized from ... More detail on these enzymes can be found in the article for methionine synthase. Homocysteine can cyclize to give homocysteine ...

The N-terminal domain is a cysteine, histidine-dependent aminohydrolase amidase. Structurally the synthetase and amidase ... Targeting trypanothione synthase could be a novel way of preventing and curing these diseases through disruption of the ... Evidence for this regulation is that the residues which allow the synthase domain to block the amidase active site are highly ... The main function of trypanothione synthase is to use the free energy generated from ATP hydrolysis to conjugate glutathione ...