Meyer TE, Habener JF (Nov 1992). "Cyclic AMP response element binding protein CREB and modulator protein CREM are products of ... Pongubala JM, Atchison ML (Apr 1995). "Activating transcription factor 1 and cyclic AMP response element modulator can modulate ... "The cyclic AMP response element modulator family regulates the insulin gene transcription by interacting with transcription ... Fujimoto T, Fujisawa J, Yoshida M (Feb 1994). "Novel isoforms of human cyclic AMP-responsive element modulator (hCREM) mRNA". ...
"The cyclic AMP response element modulator family regulates the insulin gene transcription by interacting with transcription ... "Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function". J. Virol. 68 (11): 7188-99. doi: ...
Pongubala JM, Atchison ML (1995). "Activating transcription factor 1 and cyclic AMP response element modulator can modulate the ... Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene. This gene encodes an ... Soubt MK, Marksitzer R, Menoud PA, Nagamine Y (1998). "Role of tissue-specific transcription factor LFB3 in a cyclic AMP- ... Sun P, Lou L, Maurer RA (1996). "Regulation of activating transcription factor-1 and the cAMP response element-binding protein ...
Pongubala JM, Atchison ML (April 1995). "Activating transcription factor 1 and cyclic AMP response element modulator can ...
Chronic ethanol administration decreases phosphorylation of cyclic AMP response element-binding protein in granule cells of rat ... Poo, M.M. (2001). Neurotrophins as synaptic modulators. Nat Rev Neurosci, 2, 24-32 102. Yan, Q.S., Feng, M.J., Yan, S.E. (2005 ... Ethanol exposure alters the phosphorylation of cyclic AMP responsive element binding protein and cyclic AMP responsive element ... Pandey, S.C. (2004). The gene transcription factor cyclic AMP responsive element binding protein: role in positive and negative ...
Drosophila Cyclic-AMP response element binding protein A - The Interactive Fly Drosophila Cyclic-AMP response element binding ... cAMP response element modulator) and ATF-1 (activating transcription factor-1) proteins. CREB proteins are expressed in many ... The cAMP response element (CRE) is the response element for CREB which contains the highly conserved nucleotide sequence, 5'- ... "Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene". Nature. 328 (6126): 175-178. Bibcode ...
DNA in the cell nucleus binds to phosphorylated proteins through the cyclic AMP response element (CRE), which results in the ... Small-molecule positive allosteric modulators of the FSHR have been developed. Alfred G. Gilman and Martin Rodbell received the ... For a cell to respond to FSH, only a small percentage (~1%) of receptor sites need to be activated.[citation needed] Cyclic AMP ... The cyclic AMP-regulatory dimers are degraded by phosphodiesterase and release 5'AMP. ...
Also, 3C and 2A are responsible for down-regulation of cyclic AMP responsive element binding protein (CREB), a cellular ... Hepatitis A 3C protease cleaves NEMO at the Q304 residue; NEMO is a NF-κB essential modulator responsible for activation of ... interferon (IFN) antiviral response. Cys24Ser (C24S) is a homolog of Hepatitis 3C proteinase, is responsible for inactivating ...
Group III receptors are linked to the inhibition of the cyclic AMP cascade. Activation of GRM4 has potential therapeutic ... "p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing ... Williams R, Niswender CM, Luo Q, Le U, Conn PJ, Lindsley CW (Feb 2009). "Positive allosteric modulators of the metabotropic ... Beqollari D, Kammermeier PJ (Jul 2008). "The mGlu(4) receptor allosteric modulator N-phenyl-7-(hydroxyimino)cyclopropa[b] ...
... induction by bradykinin in human pulmonary artery smooth muscle cells is mediated by the cyclic AMP response element through a ... "Structural features of subtype-selective EP receptor modulators". Drug Discovery Today. 22 (1): 57-71. doi:10.1016/j.drudis. ... EP2 also activates the a) GSK-3 pathway which regulates cell migratory responses and innate immune responses including pro- ... A 2021 study found that inhibition of myeloid cell EP2 signalling can reverse or prevent an inflammation element of brain- ...
3). In the nucleus the dimer interacts with progesterone hormone response element in the DNA causing upregulation or ... and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor". Molecular and Cellular Biology. ... Phytoprogestogen Selective androgen receptor modulator Selective estrogen receptor modulator Selective glucocorticoid receptor ... Progesterone receptor modulators with unique nonsteroidal structures are currently in the early stages of development (Fig. 5- ...
... growth hormone response element) IGF-1 and IGFBP-3 expression Via THR/THRE (thyroid hormone response element) Angiotensinogen ... "Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte". Development. 136 (11): ... "The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration". Annals of the New York Academy of ... Then, it converts adenosine triphosphate into cyclic AMP, which activates Protein kinase A. PKA leads to protein tyrosine ...
Manganiello V, Evans WH, Stossel TP, Mason RJ, Vaughan M. The effect of polystyrene beads on cyclic AMP concentration in human ... Mechanical responses of white blood cells. In: Inflammation. Basic Mechanism and Clinical Correlates. J. Gallin, I. Goldstein, ... In: Cytoskeletal Elements and Plasma Membrane Organization, Poste G, Nicolson GL, eds, Elsevier, Amsterdam, 1981; 140-168. 41. ... pGSN is a master regulator-a key immune modulator that balances the inflammatory process to prevent the spread of excess ...
CREB (cAMP response element binding protein) belongs to a family of transcription factors and is positioned in the nucleus of ... Keshwani MM, Kanter JR, Ma Y, Wilderman A, Darshi M, Insel PA, Taylor SS (October 2015). "Mechanisms of cyclic AMP/protein ... which has been shown to be a cellular growth factor modulator with met-enkephalin being the endogenous ligand. This receptor is ... The CREB protein binds to cAMP response elements CRE, and can either increase or decrease the transcription of certain genes. ...