... , also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement ... and a cofactor protein (Factor H, C4b-binding protein, complement receptor 1, and membrane cofactor protein). Upon binding of ... Whaley K (March 1980). "Biosynthesis of the complement components and the regulatory proteins of the alternative complement ... is a protein of the complement system, first isolated in 1966 in guinea pig serum, that regulates complement activation by ...

Complement+Inactivator+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (CS1: long volume ... Complement control protein are proteins that interact with components of the complement system. The complement system is ... Complement control proteins also play a role in malignancy. Complement proteins protect against malignant cells- both by direct ... motifs in complement control protein domains determine functionality in regulators of complement activation-family proteins". ...

... cells from complement-mediated damage. CFHR5 (Complement Factor H-Related protein 5) is able to bind to act as a cofactor for ... Pangburn MK, Schreiber RD, Müller-Eberhard HJ (July 1977). "Human complement C3b inactivator: isolation, characterization, and ... there are several different kinds of regulatory proteins that disrupt the complement activation process: Complement Receptor 1 ... Factor I requires a C3b-binding protein cofactor such as complement factor H, CR1, or Membrane Cofactor of Proteolysis (MCP or ...

C4b-binding protein inhibits the haemolytic function of cell-bound C4b. C4b-binding protein and C3b inactivator control the C3 ... complement receptor 1 (CR1), C4b-binding protein and Factor H. Convertase assembly is suppressed by the proteolytic cleavage of ... "Modulation of the Classical Pathway C3 Convertase by Plasma Proteins C4 Binding Protein and C3b Inactivator". Proc Natl Acad ... C4 binding protein (C4BP) interferes with the assembly of the membrane-bound C3 convertase of the classical pathway. C4BP is a ...

"Characterization of the streptococcal C5a peptidase using a C5a-green fluorescent protein fusion protein substrate". Journal of ... Wexler DE, Chenoweth DE, Cleary PP (December 1985). "Mechanism of action of the group A streptococcal C5a inactivator". ... Bohnsack JF, Mollison KW, Buko AM, Ashworth JC, Hill HR (February 1991). "Group B streptococci inactivate complement component ...

... complement c1 inactivator proteins MeSH D12.776.124.486.274.920.250.500 - complement c1 inhibitor protein MeSH D12.776.124.486. ... complement c3b inactivator proteins MeSH D12.776.124.486.274.920.325.200 - complement factor h MeSH D12.776.124.486.274.920. ... complement factor b MeSH D12.776.124.486.274.920 - complement inactivator proteins MeSH D12.776.124.486.274.920.124 - antigens ... 325.210 - complement factor i MeSH D12.776.124.486.274.920.662 - complement c4b-binding protein MeSH D12.776.124.486.274.930 - ...

The full complement of Gla is required to give full activity to protein C. (2) beta-Hydroxylation of Asp71 in one of the two ... "protein C (inactivator of coagulation factors Va and VIIIa)". The gene's symbol approved by the HUGO Gene Nomenclature ... Activated protein C-protein C inhibitor ^ α: GLA-domainless protein C is produced by selective proteolysis between residues 82 ... Walker FJ (June 1980). "Regulation of activated protein C by a new protein. A possible function for bovine protein S". The ...

M protein also inhibits opsonization by the alternative complement pathway by binding to host complement regulators. The M ... Wexler DE, Chenoweth DE, Cleary PP (1985). "Mechanism of action of the group A streptococcal C5a inactivator". Proc Natl Acad ... As of 2016, a total of 120 M proteins are identified. These M proteins are encoded by 234 types emm gene with greater than ... In addition, the capsule and several factors embedded in the cell wall, including M protein, lipoteichoic acid, and protein F ( ...