Nilsson, U. R.; Nilsson, B. (1984-08-03). "Simplified assays of hemolytic activity of the classical and alternative complement ... Hajime, K (1983). "A Simple Procedure for the Titration of Total Hemolytic Complement Activity". Japanese Journal of Clinical ... Total complement activity (TCA) refers to a series of tests that determine the functioning of the complement system in an ... Costabile, Maurizio (March 29, 2010). "Measuring the 50% Haemolytic Complement (CH50) Activity of Serum". J. Vis. (37). doi: ...
... complement hemolytic activity assay MeSH E05.478.468.429 - lymphocyte culture test, mixed MeSH E05.478.550.520 - immunization, ... complement hemolytic activity assay MeSH E05.196.922.500 - conductometry MeSH E05.196.922.625 - neutralization tests MeSH ... colony-forming units assay MeSH E05.200.500.383.910 - tumor stem cell assay MeSH E05.200.500.385 - cytogenetic analysis MeSH ... drug screening assays, antitumor MeSH E05.337.550.200.800 - tumor stem cell assay MeSH E05.337.550.200.900 - xenograft model ...
... complement fixation tests MeSH E01.450.495.735.155 - complement hemolytic activity assay MeSH E01.450.495.735.360 - ... complement hemolytic activity assay MeSH E01.450.495.225 - fluorescent antibody technique MeSH E01.450.495.225.050 - antibody- ... local lymph node assay MeSH E01.370.750.600 - passive cutaneous anaphylaxis MeSH E01.370.750.610 - patch tests MeSH E01.370. ... local lymph node assay MeSH E01.450.495.750.600 - passive cutaneous anaphylaxis MeSH E01.450.495.750.610 - patch tests MeSH ...
... including megaloblastic anemia and autoimmune hemolytic anemia. False-negative results can occur when complement activity is ... Flow cytometry is the most sensitive and useful assay currently available to screen and diagnosis PNH. The sucrose lysis test ... which triggers the activation of the classic complement pathway, leading to the lysis of cells that are sensitive to complement ... The test works by using sucrose, which creates a low ionic strength environment that allows complement to bind to red blood ...
... since enzymes of hemolytic and dermonecrotic activity were reported in Sicarius, with an action similar to that of Loxosceles. ... The venom is capable of causing complement-dependent hemolysis and cytotoxic activity against human skin fibroblasts in ... since adults possess up to eight times the concentration assayed. Sicarius thomisoides venom also has extremely ... Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms". Toxins. 12 (2): 91. doi:10.3390/toxins12020091. PMC ...
H. influenzae will not grow outside the hemolytic zone of S. aureus due to the lack of nutrients such as factor V in these ... Polymerase chain reaction (PCR) assays have been proven to be more sensitive than either LAT or culture tests, and are highly ... Their capsule allows them to resist phagocytosis and complement-mediated lysis in the nonimmune host. The unencapsulated ... Fluoroquinolone-resistant Haemophilus influenzae have been observed.) Macrolides and fluoroquinolones have activity against non ...
In whole serum, C4B alleles performed at a rate several fold greater during hemolytic activity, in direct comparison with C4A ... study, they utilized the real-time polymerase chain reaction (rt-PCR) as an assay to determine the copy number variance (CNV) ... Complement component 4A Complement component 4B HLA A1-B8-DR3-DQ2 haplotype Complement system Complement deficiency Sekar A, ... Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human ...
Moreover, the complement inhibitory activities of factor H, and other complement regulators, are often used by pathogens to ... The current theory is that complement dysregulation is a key driver of chronic inflammation in AMD. Hemolytic uremic syndrome ( ... and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay". ... Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I ...
August 2008). "Hemolytic transfusion reactions after administration of intravenous immune (gamma) globulin: a case series ... Nimmerjahn F, Ravetch JV (January 2007). "The antiinflammatory activity of IgG: the intravenous IgG paradox". The Journal of ... and can interfere with many of the IgG-based assays often used to diagnose a patient with a particular infection. After ... the possibility that IgG stimulates the host's complement system, leading to enhanced removal of all antibodies, including the ...
Hemolytic anemia contributes to jaundice. A feature of leptospirosis is acute haemolytic anaemia and conjugated ... It also secretes proteases to degrade complement proteins such as C3. It can bind to thrombin that decreases the fibrin ... The disease is also related to adventure tourism and recreational activities. It is common among water-sports enthusiasts in ... Rapid detection of Leptospira can be done by quantifying the IgM antibodies using an enzyme-linked immunosorbent assay (ELISA ...
The idea of molecular mimicry arose in the context of rheumatic fever, which follows infection with Group A beta-haemolytic ... These ligands include B cell receptor (for antigen), IgG Fc receptors, CD21, which binds complement C3d, Toll-like receptors 9 ... serological assays which can detect specific autoantibodies can be employed.[citation needed] Localised disorders are best ... parasite infection is associated with reduced activity of autoimmune disease. The putative mechanism is that the parasite ...
However, current latex assays and some typing antisera have shown cross reactions with non-E. coli O157 colonies. Furthermore, ... UPEC can evade the body's innate immune defences (e.g. the complement system) by invading superficial umbrella cells to form ... This is not considered phage therapy, however, because it does not involve selection of phages with activity against a ... 29 June 2000). "The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections". N ...
2009). "Complement inhibitor eculizumab in atypical hemolytic uremic syndrome". Clin J Am Soc Nephrol. 4 (8): 1312-1316. doi: ... and assays for fibrin degradation products such as "D-Dimers", are generally normal despite the low platelet count ( ... multimers caused by congenital or acquired reductions in ADAMTS13 activity was established at approximately the same time. In ... Loirat, C; Noris, M; Fremaux-Bacchi, V (2008). "Complement and the atypical hemolytic uremia syndrome in children". Pediatr ...
Colonial Allorecognition, Hemolytic Rejection, and Viviparity in Botryllid Ascidians Bates, William R. (1988). "Polarization of ... However, non-self sperm out-compete self-sperm in fertilization competition assays. Gamete recognition is not absolute allowing ... "CiApex1 has AP endonuclease activity and abrogated AP site repair disrupts early embryonic development in Ciona intestinalis". ... "The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia". Evolutionary ...
The disorder can also be caused by a monoclonal immunoglobulin that acts as an autoantibody that activates the blood complement ... and cold-induced hemolytic anemia. IgM, IgG, and to lesser extents κ and λ free light chain myeloma proteins can cause Immune ... these cases are not plasma cell dyscrasias but rather appear to be caused by the over-activity of non-malignant immune cell ... more sensitive methods of detecting urinary and serum light chain myeloma proteins using enzyme-linked immunosorbent assays ...
Arimi, S.M.; Park, R.W.A.; Fricker, C.R. (September 1990). "Study of haemolytic activity of some Campylobacter spp. on blood ... C. fetus can be diagnosed with polymerase chain reaction assays, enzyme linked immunosorbent assays and vaginal mucus ... Aside from complement-mediated mechanisms, C. fetus has also evolved variation in its S-layer proteins (SLPs) of the S-layer to ... assays, enzyme linked immune sorbent assays (ELISA), and vaginal mucus agglutination test (VMAT). Diagnosis depends on ...
... these phagocytes are attracted by certain complement molecules generated in the complement cascade. Second, some complement ... BAU (binding antibody unit, often as BAU/mL) is a measurement unit defined by the WHO for the comparison of assays detecting ... Its role is in modulating immune cell activity: it is where effector molecules bind to, triggering various effects after the ... Urbaniak SJ, Greiss MA (March 2000). "RhD haemolytic disease of the fetus and the newborn". Blood Reviews. 14 (1): 44-61. doi: ...
Exotoxin activity can be separated into specific cytotoxic activity or broad cytotoxic activity based on whether the toxin ... Of the commercial ways of using immunochemical detection would be enzyme-linked immunosorbent assays (ELISA). This assay has ... EHEC infections result in more severe diseases of hemorrhagic colitis and hemolytic uremic syndrome. There are around 200 ... complement and neutrophils. These secreted virulence factors assist the bacterium in surviving immune response mechanisms. ...
On the agar plates, B. pseudomallei forms creamy, non-haemolytic, colonies after 2 days of incubation. After 4 days of ... Serological tests such as indirect haemagglutination assay (IHA) have been used to detect the presence of antibodies against B ... Limmathurotsakul D, Kanoksil M, Wuthiekanun V, Kitphati R, deStavola B, Day NP, Peacock SJ (2013). "Activities of daily living ... B. pseudomallei triggers both the complement system and coagulation cascade, however the thick bacterial capsule prevent the ...