"Entrez Gene: COL12A1 collagen, type XII, alpha 1". "Collagen, Type XII, Alpha-1; COL12A1 Gene-Phenotype Relationships". Online ... collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to ... This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted ... April 1997). "Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen ( ...

Its occurrence in collagen types VI, VII, XII and XIV, the integrins and other proteins by averaged structure predictions". J. ... Collagen, type I, alpha 1 (COL1A1) Collagen, type II, alpha 1 (COL2A1) Collagen, type III, alpha 1 (COL3A1) Collagen, type V, ... collagen types VI, VII, XII and XIV; and other extracellular proteins. Although the majority of VWA-containing proteins are ... "Type A modules: interacting domains found in several non-fibrillar collagens and in other extracellular matrix proteins". ...

Its occurrence in collagen types VI, VII, XII and XIV, the integrins and other proteins by averaged structure predictions". J. ... collagen types VI, VII, XII and XIV; and other extracellular proteins. Although the majority of vWA-containing proteins are ... Colombatti A, Bonaldo P, Doliana R (1993). "Type A modules: interacting domains found in several non-fibrillar collagens and in ... This type A domain is the prototype for a protein superfamily (InterPro: IPR036465; see also Pfam clan). The vWA domain is ...

FACIT collagens include collagen types IX, XII, XIV, XIX, and XXI. Triple helix Collagen helix GO term: FACIT collagen[ ... There are eight known types of FACIT collagens: collagens IX, XII, XIV, XVI, XIX, XXI, and XXII. The general FACIT collagen ... FACIT collagen (Fibril Associated Collagens with Interrupted Triple helices) is a type of collagen and also a proteoglycan that ... Other collagen types such as Collagen XX, which are smaller in size are mostly expressed in the connective tissue such as ...

... contains type I collagen and type XII collagen. Michael H. Ross. Histology: A Text and Atlas, with Correlated ... Perichondrium is a type of irregular collagenous ordinary connective tissue, and also functions in the growth and repair of ... Biosynthesis and Gene Regulation of Collagens in Cartilage and Bone", Dynamics of Bone and Cartilage Metabolism (Second Edition ... 3-40, doi:10.1016/b978-012088562-6/50002-9, ISBN 978-0-12-088562-6, retrieved 2020-11-18 Iowa Histology Index 4/iv-05 - "Slide ...

Found to have type I, III, VI, and XII collagen. Connective tissue in skeletal muscle Endomysium Epimysium E. Passerieux, R. ... The overall comprehensive organization of the perimysium collagen network, as well as its continuity and disparateness, however ...

... type III collagen is also an important regulator of the diameter of type I and II collagen fibrils. Type III collagen is also ... types I, II, III, and XI), fibril-associated collagen (type IX), and network-forming collagen (type X) cause a spectrum of ... Type III collagen could also be important in several other human diseases. Increased amounts of type III collagen are found in ... Type III collagen is one of the fibrillar collagens whose proteins have a long, inflexible, triple-helical domain. Type III ...

... related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type ... Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in ... type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This ... "Entrez Gene: COL5A3 collagen, type V, alpha 3". van der Rest M, Garrone R (1991). "Collagen family of proteins". FASEB J. 5 (13 ...

It is ubiquitously expressed in many tissues and cell types. COL4A1 is a subunit of the type IV collagen and plays a role in ... collagen". FEBS Letters. 225 (1-2): 188-94. doi:10.1016/0014-5793(87)81155-9. PMID 3691802. "Entrez Gene: COL4A1 collagen, type ... Type IV collagen is the major structural component of basement membranes, which contains two or three COL4A1 proteins. Thus, ... COL4A1 belongs to the type IV collagen family and contains three domains: a short N-terminal domain, a long triple-helical 7S ...

Type XI collagen also helps maintain the spacing and diameter of type II collagen fibrils. Type II collagen is an important ... types I, II, III, and XI), fibril-associated collagen (type IX), and network-forming collagen (type X) cause a spectrum of ... Instead, another type of collagen chain replaces pro-alpha2(XI) to form type XI collagen in the vitreous of the eye. COL11A2 ... The COL11A2 gene produces one component of this type of collagen, called the pro-alpha2(XI) chain. Type XI collagen adds ...

2005). "Collagen types XII and XIV are present in basement membrane zones during human embryonic development". J. Mol. Histol. ... "Entrez Gene: COL14A1 collagen, type XIV, alpha 1 (undulin)". "COL14A1 - Collagen alpha-1(XIV) chain precursor - Homo sapiens ( ... Tono-Oka S, Tanase S, Miike T, Tanaka H (1996). "Transient expression of collagen type XIV during muscle development and its ... Collagen alpha-1(XIV) chain is a protein that in humans is encoded by the COL14A1 gene. It likely plays a role in collagen ...

"Czech dysplasia metatarsal type: another type II collagen disorder". European Journal of Human Genetics. 15 (12): 1269-1275. ... Czech dysplasia metatarsal type is a rare type of Czech dysplasia which is characterized primarily by bone anomalies. ... "Czech dysplasia metatarsal type - About the Disease - Genetic and Rare Diseases Information Center". rarediseases.info.nih.gov ... "Orphanet: Czech dysplasia metatarsal type". www.orpha.net (in Spanish). Retrieved 2022-07-07. Marik, Ivo; Marikova, Olga; ...

Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have ... sites in bovine cartilage type IX collagen reveals an antiparallel type II-type IX molecular relationship and type IX to type ... This gene encodes one of the three alpha chains of type IX collagen, a collagen component of hyaline cartilage. ... "Entrez Gene: COL9A1 collagen, type IX, alpha 1". GeneReviews/NCBI/NIH/UW entry on Multiple Epiphyseal Dysplasia, Dominant ...

Type XV collagen is known to be a tumor suppressor that can be used to understand tumor cells environment. Type XV collagen ... This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with ... "Epitope-defined monoclonal antibodies against multiplexin collagens demonstrate that type XV and XVIII collagens are expressed ... Hägg PM, Hägg PO, Peltonen S, Autio-Harmainen H, Pihlajaniemi T (June 1997). "Location of type XV collagen in human tissues and ...

... types I, II, III, and XI), fibril-associated collagen (type IX), and network-forming collagen (type X) cause a spectrum of ... Collagen, type I, alpha 1, also known as alpha-1 type I collagen, is a protein that in humans is encoded by the COL1A1 gene. ... the structure of type I collagen is compromised. Tissues that are rich in type I collagen, such as the skin, bones, and tendons ... Ehlers-Danlos type IV is most attributed to abnormalities in the reticular fibers (collagen Type III). Ehlers-Danlos syndrome, ...

This protein is an alpha chain of type VI collagen that aids in microfibril formation. As part of type VI collagen, this ... This gene encodes the alpha 3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in ... "The 1.6 A structure of Kunitz-type domain from the alpha 3 chain of human type VI collagen". Journal of Molecular Biology. 246 ... "Anisotropic behaviour of the C-terminal Kunitz-type domain of the alpha3 chain of human type VI collagen at atomic resolution ( ...

... chain of type II collagen. This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and ... "A COL2A1 mutation in achondrogenesis type II results in the replacement of type II collagen by type I and III collagens in ... type 2 by affecting tissues that are rich in type II collagen. Platyspondylic lethal skeletal dysplasia, Torrance type:Fewer ... chain that cannot be incorporated into type II collagen fibers. As a result, cells make a reduced amount of type II collagen. ...

XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13". ... This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with ... other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve ... "Entrez Gene: COL19A1 collagen, type XIX, alpha 1". Yoshioka H, Zhang H, Ramirez F, et al. (1992). "Synteny between the loci for ...

... related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type ... Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in ... "Entrez Gene: COL5A2 collagen, type V, alpha 2". Mann K (1992). "Isolation of the alpha 3-chain of human type V collagen and ... type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This ...

... related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type ... Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in ... "Entrez Gene: COL5A1 collagen, type V, alpha 1". Mann K (1992). "Isolation of the alpha 3-chain of human type V collagen and ... type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This ...

"Entrez Gene: COL8A2 collagen, type VIII, alpha 2". Shuttleworth CA (1998). "Type VIII collagen". Int. J. Biochem. Cell Biol. 29 ... Illidge C, Kielty C, Shuttleworth A (1998). "The alpha1(VIII) and alpha2(VIII) chains of type VIII collagen can form stable ... 1991). "The alpha 2(VIII) collagen gene. A novel member of the short chain collagen family located on the human chromosome 1". ... the gene encoding the alpha2 chain of type VIII collagen, cause two forms of corneal endothelial dystrophy". Hum Mol Genet. 10 ...

Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. ... sites in bovine cartilage type IX collagen reveals an antiparallel type II-type IX molecular relationship and type IX to type ... This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. ... "Entrez Gene: COL9A2 collagen, type IX, alpha 2". GeneReviews/NCBI/NIH/UW entry on Multiple Epiphyseal Dysplasia, Dominant ...

Fibril Associated Collagens with Interrupted Triple Helices) (Type IX, XII, XIV, XIX, XXI) Short chain (Type VIII, X) Basement ... of the collagen in the human body is type I collagen. However, as of 2011, 28 types of human collagen have been identified, ... Type XIII, XVII) Microfibril forming (Type VI) Anchoring fibrils (Type VII) The five most common types are: Type I: skin, ... With type I collagen and possibly all fibrillar collagens, if not all collagens, each triple-helix associates into a right- ...

Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. ... sites in bovine cartilage type IX collagen reveals an antiparallel type II-type IX molecular relationship and type IX to type ... This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. ... "Entrez Gene: COL9A3 collagen, type IX, alpha 3". GeneReviews/NCBI/NIH/UW entry on Multiple Epiphyseal Dysplasia, Dominant ...

... or collagen IV NC1 domain) is a duplicated domain present at the C-terminus of type IV collagens. Each type IV collagen ... Structural basis for type IV collagen assembly in basement membranes". J. Biol. Chem. 277 (34): 31142-53. doi:10.1074/jbc. ... In molecular biology, the type IV collagen C4 domain ( ... The collagen IV C4 domain is composed of two similarly folded ... domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link". Proc. Natl. Acad. ...

UCMD1 is associated with variants of type VI collagen, while UCMD2 is associated with variants of type XII collagen. UCMD is ... "COL6A1 collagen type VI alpha 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2016-05-11. Bushby KM, ... Alpha 1 subunit of type VI collagen is the encoded protein. In terms of the genetics of UCMD2, there are mutations in the gene ... Collagen type VI myopathies. Adv Exp Med Biol 802:185-199 Reed, Umbertina Conti; Ferreira, Lucio Gobbo; Liu, Enna Cristina; ...

Its occurrence in collagen types VI, VII, XII and XIV, the integrins and other proteins by averaged structure predictions". J. ... Von Willebrand factor type D domain (vWD) is an evolutionarily-conserved protein domain found in, among others, the von ... "The secondary structure of the von Willebrand factor type A domain in factor B of human complement by Fourier transform ... Willebrand factor (vWF). vWF is a large multimeric glycoprotein and it is synthesized by a type of bone marrow cell called ...

Collagen, type I, alpha 1 Collagen, type II, alpha 1 Collagen, type III, alpha 1 Collagen, type IV, alpha 1 Collagen, type V, ... type VI, alpha 1 Collagen, type VII, alpha 1 Collagen, type VIII, alpha 1 Collagen, type IX, alpha 1 Collagen, type X, alpha 1 ... collagen (type I, II, VI, X collagen fibrils) and proteoglycans. The ratio and the proportion of collagen play an important ... "Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen". Cell and ...

... is caused by a mutation on the COL12A1 gene coding for type XII collagen. It is autosomal dominant. Gowers's sign, toe walking ... There are two types of Bethlem myopathy, based on which type of collagen is affected. Bethlem myopathy 1 (BTHLM1), formerly ... is caused by a mutation in one of the three genes coding for type VI collagen. These include COL6A1, COL6A2, and COL6A3. It is ... Bethlem myopathy 2 (BTHLM2), formerly known as myopathic-type Ehlers-Danlos syndrome, ...

Ullrich congenital muscular dystrophy and Bethlem myopathy - defects in collagen (type VI and XII), results in progressive ... Psoriatic arthritis is also a collagen vascular disease. Peyronie's disease - involving the growth of abnormal collagen (Type I ... Type I or III) and cause progressive deterioration of collagen, with different EDS types affecting different sites in the body ... Diseases in which inflammation or weakness of collagen tends to occur are also referred to as collagen diseases. Collagen ...