"Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia". Science Translational Medicine ... "Clonal evolution in myelodysplastic syndromes". Nature Communications. 8: 15099. Bibcode:2017NatCo...815099D. doi:10.1038/ ... as having Clonal Hematopoiesis of Indeterminate Potential (CHIP). A clonal involvement (sometimes referred to simply as the ... of the population over age 70 has observable clonal hematopoiesis. Having clonal hematopoiesis has been linked to a more than ...
This allows evolution to proceed more rapidly, a phenomenon known as the Hill-Robertson effect. On the contrary, in asexually ... Clonal interference does not only play a role in the fixation of mutations in chromosomal DNA, but it also influences the ... The phenomenon of clonal interference also occurs in cancer and pre-cancer cell lineages within a patient. The heterogeneity ... The idea of clonal interference was introduced by American geneticist Hermann Joseph Muller in 1932. It explains why beneficial ...
Greaves M, Maley CC (January 2012). "Clonal evolution in cancer". Nature. 481 (7381): 306-313. Bibcode:2012Natur.481..306G. doi ... Evolutionary therapy relies on the notion that Darwinian evolution is the main reason behind lethality of late stage cancer and ... Card KJ, LaBar T, Gomez JB, Lenski RE (October 2019). "Historical contingency in the evolution of antibiotic resistance after ... These obstacles include high contingency of trajectory, speed of evolution, and inability to track the population state of ...
Loxdale HD, Lushai G. (2003) Rapid changes in clonal lines: the death of a 'sacred cow'. Biological Journal of the Linnean ... Loxdale HD (2009) What's in a clone: the rapid evolution of aphid asexual lineages in relation to geography, host plant ... Loxdale has written reviews on absence of strict genetic uniformity in populations of clonal organisms such as aphids. This ... These include the migration and dispersal of insects in relation to their genotype and habitat; intra-clonal genetic variation ...
Some clonal types disappeared entirely. Meanwhile, sexual snail populations remained much more stable over time. However, ... It is probable that the evolution of sex was an integral part of the evolution of the first eukaryotic cell. There are a few ... Ridley, Mark (2003). Evolution (3rd ed.). Wiley. p. 314. ISBN 9781405103459. Beukeboom, L. & Perrin, N. (2014). The Evolution ... Hoekstra, Rolf F. (1987). "The Evolution of Sexes". In Stearns, Stephen C. (ed.). The Evolution of Sex and its Consequences. ...
Among the clonal population of these aphids, there may be several distinct morphs and this lays the foundation for a possible ... Chen, Rui; Wang, Zhe; Chen, Jing; Jiang, Li-Yun; Qiao, Ge-Xia (2017). "Insect-bacteria parallel evolution in multiple-co- ... However, there are differences between these sexual social insects and the clonal aphids, which are all descended from a single ... Eggs are parthenogenetically produced without meiosis and the offspring are clonal to their mother, so they are all female ( ...
... better known as the somatic evolution model. The clonal evolution model, which occurs in both the CSC model and stochastic ... According to the "stochastic model" (or "clonal evolution model") every cancer cell in a tumor could gain the ability to self- ... 4). These two models are not mutually exclusive, as CSCs themselves undergo clonal evolution. Thus, the secondary more dominant ... Nowell PC (October 1976). "The clonal evolution of tumor cell populations". Science. 194 (4260): 23-8. Bibcode:1976Sci...194... ...
... there is an involvement of multiple cycles of clonal and non-clonal expansion. Even at the typical clonal expansion phase, ... focusing on research in evolution in cancer and somatic evolution Carlo Maley's lab, focusing on research in evolution in ... Cancer stem cell arises by clonal evolution as a result of selection for the cell with the highest fitness in the neoplasm. ... de Grouchy J, de Nava C, Cantu JM, Bilski-Pasquier G, Bousser J (September 1966). "Models for clonal evolutions: a study of ...
Thus, the process of carcinogenesis is formally a process of Darwinian evolution, known as somatic or clonal evolution. ... Nowell, Peter C. (1 October 1976). "The Clonal Evolution of Tumor Cell Populations: Acquired genetic lability permits stepwise ... Nowell PC (October 1976). "The clonal evolution of tumor cell populations". Science. 194 (4260): 23-8. Bibcode:1976Sci...194... ... Just as a population of animals undergoes evolution, an unchecked population of cells also can undergo "evolution". This ...
These are the cancer stem cell model and the clonal evolution model. The models are not mutually exclusive, and it is believed ... Stem cell variability is often caused by epigenetic changes, but can also result from clonal evolution of the CSC population ... This has been suggested as a reliable method for tracking clonal evolution. However, this technique proves challenging in ... Nowell, P. C. (1976). "The clonal evolution of tumor cell populations". Science. 194 (4260): 23-28. Bibcode:1976Sci...194...23N ...
... termed clonal evolution, drives progression towards more invasive stages. Clonal evolution leads to intra-tumour heterogeneity ... Murgia C, Pritchard JK, Kim SY, Fassati A, Weiss RA (August 2006). "Clonal origin and evolution of a transmissible cancer". ... This rebellion-like scenario is an undesirable survival of the fittest, where the driving forces of evolution work against the ... Cancers usually arise from an assemblage of mutations and epimutations that confer a selective advantage leading to clonal ...
Murgia C, Pritchard JK, Kim SY, Fassati A, Weiss RA (August 2006). "Clonal origin and evolution of a transmissible cancer". ... Rebbeck CA, Thomas R, Breen M, Leroi AM, Burt A (September 2009). "Origins and evolution of a transmissible cancer". Evolution ... The evolution of transmissible cancer is unlikely, because the cell clone must be adapted to survive a physical transmission of ... The evolution of transmissible cancer has occurred naturally in other animal species, but human cancer transmission is rare. In ...
"Dynamic evolution of clonal epialleles revealed by methclone". Genome Biology. 15 (9): 472. doi:10.1186/s13059-014-0472-5. ISSN ... Mason, Christopher E. (2006). Genome evolution between Drosophila melanogaster and Drosophila pseudoobscura (PhD thesis). Yale ...
Murgia, C; Pritchard JK; Kim SY; Fassati A; Weiss RA (2006-08-11). "Clonal Origin and Evolution of a Transmissible Cancer". ... Rebbeck CA, Thomas R, Breen M, Leroi AM, Burt A (2009). "Origins and Evolution of a Transmissible Cancer". Evolution. 63 (9): ... Belov, Katherine; Jones, Elizabeth; Cheng, Yuanyuan (September 2015). "The origin, dynamics, and molecular evolution of ...
Clonal origin and evolution of a transmissible cancer. Cell. 2006 Aug 11;126(3):477-87. Gomez-Raya L, Olsen HG, Lingaas F, ...
Given this insignificant level of clonal mixing, there is a low chance for barriers to the evolution and propagation of an ... the researchers were able to examine the degree of clonal mixing in the colony. Clonal mixing is defined as the "mixing" of ... So, the researchers concluded that the aphids do not adapt to short-term changes in the colony via a reduction of clonal mixing ... However, further studies on colonies where the level of clonal mixing is predicted to be high would enable researchers to gain ...
"The evolution of agriculture in beetles (Curculionidae: Scolytinae and Platypodinae)". Evolution. 55 (10): 2011-2027. doi: ... All ambrosia fungi are probably asexual and clonal. Some beetles are known to acquire ("steal") fungal inoculum from fungal ... During their evolution, most scolytid and platypodid weevils became progressively more or less dependent on fungi regularly co- ... This evolution had various outcomes in different groups: Some phloem-eating bark beetles (phloeophages) are vectors of ...
Evolution; International Journal of Organic Evolution. 46 (6): 1935-1944. doi:10.1111/j.1558-5646.1992.tb01179.x. ISSN 1558- ... Avise, John C. (2015-07-21). "Evolutionary perspectives on clonal reproduction in vertebrate animals". Proceedings of the ... Schlupp, Ingo (2005). "The Evolutionary Ecology of Gynogenesis". Annual Review of Ecology, Evolution, and Systematics. 36: 399- ... Evolution. 34 (5): 917-922. doi:10.2307/2407997. hdl:2027.42/137459. ISSN 0014-3820. JSTOR 2407997. PMID 28581138. (Wikipedia ...
Watson, James D. (1 May 1971). "Moving Toward the Clonal Man". The Atlantic. Archived from the original on 28 March 2023. ... Sims Bainbridge, William (October 2003). "Religious Opposition to Cloning". Journal of Evolution and Technology. 13. Archived ... ISBN 978-0-470-71479-9. Lederberg, Joshua (1966). "Experimental Genetics and Human Evolution". The American Naturalist. 100 ( ... "Moving Toward the Clonal Man", in 1971. With the cloning of a sheep known as Dolly in 1996 by somatic cell nuclear transfer ( ...
"Clonal genome evolution and rapid invasive spread of the marbled crayfish". Nature Ecology & Evolution. 2 (3): 567-573. doi: ...
... and diploid LR females generate clonal LL and clonal R gametes respectively, instead of recombined L and clonal LR. P. lessonae ... The genetics, ecology, and evolution of sexual abstinence in vertebrate animals. New York, Oxford University Press: i-xi + 1- ... esculentus (genotype RL) exclude here the P. ridibundus (R) or P. lessonae (L) genome in a 3:1 ratio and make mainly clonal P. ... esculentus (genotype RL) exclude here the P. lessonae genome (L) and make exclusively clonal P. ridibundus gametes (R). In ...
"Clonal genome evolution and rapid invasive spread of the marbled crayfish". Nature Ecology & Evolution. 2 (3): 567-573. doi: ... "Clonal genome evolution and rapid invasive spread of the marbled crayfish". Nature Ecology & Evolution. 2 (3): 567-573. doi: ... Günter Vogt (2010). "Suitability of the clonal marbled crayfish for biogerontological research: A review and perspective, with ... Development Genes and Evolution. 216 (4): 169-184. doi:10.1007/s00427-005-0041-8. PMID 16389558. S2CID 17494732. ...
January 2012). "Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing". Nature. 481 (7382): ... A big contribution to cancer death and failed cancer treatment is clonal evolution at the cytogenetic level, for example as ... 2010). "Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors". Genome Biology. 11 (8): R82. ... October 2009). "Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution". Nature. 461 (7265): ...
Boyer, L.; Jabbour-Zahab, R.; Mosna, M.; Haag, C. R.; Lenormand, T. (2021). "Not so clonal asexuals: Unraveling the secret sex ... life of Artemia parthenogenetica". Evolution Letters. 5 (2): 164-174. doi:10.1002/evl3.216. PMC 8045904. PMID 33868712. ( ...
McGovern, Tamara N. (2002). "Sex-ratio bias and clonal reproduction in the brittle star Ophiactis savignyi". Evolution. 56 (3 ...
"The dynamics of adaptive genetic diversity during the early stages of clonal evolution". Nature Ecology & Evolution. 3 (2): 293 ... Desai, Michael M; Fisher, Daniel S; Murray, Andrew W (March 2007). "The speed of evolution and maintenance of variation in ... Tikhonov, Mikhail; Kachru, Shamit; Fisher, Daniel S (2019). "Modeling the interplay between plastic tradeoffs and evolution in ... Fisher, Daniel S (January 2013). "Asexual evolution waves: fluctuations and universality". J. Stat. Mech.: Theory Exp. 2013 (1 ...
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However, this fast evolution might also be due to these sequences' inability to repair DNA damage via template-assisted repair ... April 2018). "Clonal polymorphism and high heterozygosity in the celibate genome of the Amazon molly". Nature Ecology & ... Evolution of sexual reproduction Genetic hitchhiking Hill-Robertson effect Muller HJ (1932). "Some genetic aspects of sex". ... original paper as cited by, e.g.: Smith JM, Szathmary E (1997). The major transitions in evolution. Oxford, New York, Tokyo: ...
... clonal evolution or a phenotypic mimic?". Human Pathology. 32 (10): 1102-1108. doi:10.1053/hupa.2001.28252. PMID 11679945. ... will eventually develop the rhabdoid phenotype during tumor evolution and progression. In one large series of 902 surgically ...
Bardelli's team tweaked the clonal evolution of the tumour, via a pharmacological intervention, to provoke the persistent ... "Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients". Nature Medicine. 21 (7): 795-801 ... molecular heterogeneity and clonal evolution, both inter-patient and intra-tumour, to overcome the resistance to targeted ... One of the main focuses of his research is the study of the emergence and evolution of drug-resistant clones that can be ...