Copper-free click chemistry: Copper-free click chemistry is a bioorthogonal reaction first developed by Carolyn Bertozzi as an activated variant of an azide alkyne Huisgen cycloaddition, based on the work by Fokin and Sharpless et al. Unlike the CuAAC, Cu-free click chemistry has been modified to be bioorthogonal by eliminating a cytotoxic copper catalyst, allowing reaction to proceed quickly and without live cell toxicity.Clinical Biochemistry: Clinical Biochemistry is a peer-reviewed scientific journal covering the analytical and clinical investigation of laboratory tests in humans used for diagnosis, molecular biology and genetics, prognosis, treatment and therapy, and monitoring of disease ; the discipline of clinical biochemistry. It is the official journal of the Canadian Society of Clinical Chemists.Outline of organic chemistry: The following outline is provided as an overview of and topical guide to organic chemistry:Serum-separating tube: Serum-separating tubes, also known as serum separator tubes or SSTs, are used in medical clinical chemistry tests requiring blood serum.C4H7N3O3Process analytical chemistry: Process Analytical Chemistry (PAC), is similar to Process Analytical Technology (PAT) (for example used for the pharmaceutical industry) has its origins as a specialized form of analytical chemistry used for process manufacturing. Process analytical chemistry is the application of analytical chemistry with specialized techniques, algorithms, and sampling equipment for solving problems related to chemical processes.Noncovalent solid-phase organic synthesis: Noncovalent solid-phase organic synthesis or NC-SPOS is a form of Solid-phase synthesis whereby the organic substrate is bonded to the solid phase not by a covalent bond but by other chemical interactions. This bond may consist of an induced dipole interaction between a hydrophobic matrix and a hydrophobic anchor.Alkyne: In organic chemistry, an alkyne is an unsaturated hydrocarbon containing at least one carbon—carbon triple bond between two carbon atoms.Alkyne.ACS Medicinal Chemistry Letters: ACS Medicinal Chemistry Letters is a peer-reviewed academic journal in the field of medicinal chemistry. Founded in 2009, this online journal is published monthly by the American Chemical Society.Rosalyn Sussman YalowConvergent synthesis: In chemistry a convergent synthesis is a strategy that aims to improve the efficiency of multistep synthesis, most often in organic synthesis. In this type of synthesis several individual pieces of a complex molecule are synthesised in stage one and then in stage two these pieces are combined to form the final product Organic Synthesis, 3th Ed.Eco-friendly dentistry: Eco-friendly dentistry"What is Eco-friendly Dentistry is defined by various dentists and dental organizations and primarily consists of general dentistry, oral surgery and other specialty dental services featuring green practices to reduce impact on the eco-system, the environment and patient treatment practices.Supramolecular polymers: thumbnail|250px|An example of a quadruple [[hydrogen bonds reported by Meijer and coworkers in Angew. Chem.Food physical chemistry: Food physical chemistry is considered to be a branch of Food chemistryJohn M. de Man.Primordial soup: "Primordial soup" is a term introduced by the Soviet biologist Alexander Oparin. In 1924, he proposed a theory of the origin of life on Earth through the transformation, during the gradual chemical evolution of molecules that contain carbon in the primordial soup.Surface modification: Surface modification is the act of modifying the surface of a material by bringing physical, chemical or biological characteristics different from the ones originally found on the surface of a material.Stilbene photocyclization: Stilbene photocyclization is the coupling of two aromatic carbons in stilbenes upon ultraviolet irradiation. The reaction can be used to form polycyclic aromatic hydrocarbons and heteroaromatics.Azide: Azide is the anion with the formula N3Frank Dickens (biochemist): Frank Dickens FRS (15 December 1899 - 15 June 1986) was a biochemist, best known for his work at the Courtauld Institute of Biochemistry with Edward Charles Dodds on the pentose phosphate pathway which generates NADPH.Peter N.Reaction coordinateTable of standard reduction potentials for half-reactions important in biochemistry: The values below are standard reduction potentials for half-reactions measured at 25°C, 1 atmosphere and a pH of 7 in aqueous solution.Acid catalysis: In acid catalysis and base catalysis a chemical reaction is catalyzed by an acid or a base. The acid is the proton donor and the base is the proton acceptor.Interstellar cloud: Interstellar cloud is the generic name given to an accumulation of gas, plasma, and dust in our and other galaxies. Put differently, an interstellar cloud is a denser-than-average region of the interstellar medium.Shiva crater: The Shiva Crater is a geologic structure, which is hypothesized by Sankar ChatterjeeChatterjee, S. (1997) Multiple impacts at the KT boundary and the death of the dinosaurs.Sharpless asymmetric dihydroxylation: Sharpless asymmetric dihydroxylation (also called the Sharpless bishydroxylation) is the chemical reaction of an alkene with osmium tetroxide in the presence of a chiral quinine ligand to form a vicinal diol.Primordial sandwich: The concept of the primordial sandwich was proposed by the chemist Günter Wächtershäuser to describe the possible origins of the first cell membranes, and, therefore, the first cell.Stratosphere: The stratosphere is the second major layer of Earth's atmosphere, just above the troposphere, and below the mesosphere. It is stratified in temperature, with warmer layers higher up and cooler layers farther down.PrinomastatPolymer blend: A polymer blend or polymer mixture is a member of a class of materials analogous to metal alloys, in which at least two polymers are blended together to create a new material with different physical properties. Section 3.Submillimetre astronomy: Submillimetre astronomy or submillimeter astronomy (see spelling differences) is the branch of observational astronomy that is conducted at submillimetre wavelengths (i.e.Trapped ion quantum computer: A trapped ion quantum computer is one proposed approach to a large-scale quantum computer. Ions, or charged atomic particles, can be confined and suspended in free space using electromagnetic fields.Outline of water: The following outline is provided as an overview of and topical guide to water:Ultraviolet photoelectron spectroscopy: Ultraviolet photoelectron spectroscopy (UPS) refers to the measurement of kinetic energy spectra of photoelectrons emitted by molecules which have absorbed ultraviolet photons, in order to determine molecular orbital energies in the valence region.Copper toxicityAdsorptionNewington Green Unitarian ChurchNatron: Natron is a naturally occurring mixture of sodium carbonate decahydrate (Na2CO3·10H2O, a kind of soda ash) and about 17% sodium bicarbonate (also called baking soda, NaHCO3) along with small quantities of sodium chloride and sodium sulfate. Natron is white to colourless when pure, varying to gray or yellow with impurities.History of nanotechnology: The history of nanotechnology traces the development of the concepts and experimental work falling under the broad category of nanotechnology. Although nanotechnology is a relatively recent development in scientific research, the development of its central concepts happened over a longer period of time.Radiochemistry: Radiochemistry is the chemistry of radioactive materials, where radioactive isotopes of elements are used to study the properties and chemical reactions of non-radioactive isotopes (often within radiochemistry the absence of radioactivity leads to a substance being described as being inactive as the isotopes are stable). Much of radiochemistry deals with the use of radioactivity to study ordinary chemical reactions.Fragment-based lead discovery: Fragment-based lead discovery (FBLD) also known as fragment-based drug discovery (FBDD) is a method used for finding lead compounds as part of the drug discovery process. It is based on identifying small chemical fragments, which may bind only weakly to the biological target, and then growing them or combining them to produce a lead with a higher affinity.Spin–lattice relaxation in the rotating frame: Spin–lattice relaxation in the rotating frame is the mechanism by which Mxy, the transverse component of the magnetization vector, exponentially decays towards its equilibrium value of zero, under the influence of a radio frequency (RF) field in nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI). It is characterized by the spin–lattice relaxation time constant in the rotating frame, T1ρ.Enzyme Commission number: The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze.Volumetric heat capacity: Volumetric heat capacity (VHC), also termed volume-specific heat capacity, describes the ability of a given volume of a substance to store internal energy while undergoing a given temperature change, but without undergoing a phase transition. It is different from specific heat capacity in that the VHC is a 'per unit volume' measure of the relationship between thermal energy and temperature of a material, while the specific heat is a 'per unit mass' measure (or occasionally per molar quantity of the material).China Biologic Products, Inc.Coordination complex: In chemistry, a coordination complex or metal complex consists of a central atom or ion, which is usually metallic and is called the coordination centre, and a surrounding array of bound molecules or ions, that are in turn known as ligands or complexing agents. Many metal-containing compounds, especially those of transition metals, are coordination complexes.Analytical quality control: Analytical quality control, commonly shortened to AQC refers to all those processes and procedures designed to ensure that the results of laboratory analysis are consistent, comparable, accurate and within specified limits of precision.analytical quality control (AQC) program to ensure the highest level of confidence in reported data Constituents submitted to the analytical laboratory must be accurately described to avoid faulty interpretations, approximations, or incorrect results.Metallocene: A metallocene is a compound typically consisting of two cyclopentadienyl anions (Cp, which is C5H5−) bound to a metal center (M) in the oxidation state II, with the resulting general formula (C5H5)2M. Closely related to the metallocenes are the metallocene derivatives, e.Surface modification of biomaterials with proteins: Biomaterials are materials that are used in contact with biological systems. Biocompatibility and applicability of surface modification with current uses of metallic, polymeric and ceramic biomaterials allow alteration of properties to enhance performance in a biological environment while retaining bulk properties of the desired device.Ethyl groupCarbon chauvinism: Carbon chauvinism is a neologism meant to disparage the assumption that the chemical processes of hypothetical extraterrestrial life must be constructed primarily from carbon (organic compounds) because carbon's chemical and thermodynamic properties render it far superior to all other elements.Collision/reaction cell: A collision/reaction cell is a device used in inductively coupled plasma mass spectrometry to remove interfering ions through ion/neutral reactions.Nanoparticle: Nanoparticles are particles between 1 and 100 nanometers in size. In nanotechnology, a particle is defined as a small object that behaves as a whole unit with respect to its transport and properties.Enlightenment Intensive: An Enlightenment Intensive is a group retreat designed to enable a spiritual enlightenment experience within a relatively short time. Devised by Americans Charles (1929–2007) and Ava Berner in the 1960s,http://www.Burst kinetics: Burst kinetics is a form of enzyme kinetics that refers to an initial high velocity of enzymatic turnover when adding enzyme to substrate. This initial period of high velocity product formation is referred to as the "Burst Phase".Kodak DCS 300 series: The Kodak DCS 300 series comprised two cameras, the DCS 315 and DCS 330. They were professional-level digital SLR cameras built by Eastman Kodak's Kodak Professional Imaging Solutions division.Atomic mass: right |thumb|200px|Stylized [[lithium-7 atom: 3 protons, 4 neutrons, & 3 electrons (total electrons are ~1/4300th of the mass of the nucleus). It has a mass of 7.Perchloromethyl mercaptanNencki Institute of Experimental Biology: The Nencki Institute of Experimental Biology is a Polish scientific research organization and a part of Polish Academy of Sciences headquartered in Warsaw, Poland. Founded in 1918, it is a leading institution in the country in the field of neurobiology, molecular biology and biochemistry.NebulaCyclopentadieneDNA-encoded chemical library: DNA-encoded chemical libraries (DEL) is a technology for the synthesis and screening of collections of small molecule compounds of unprecedented size. DEL is used in medicinal chemistry to bridge the fields of combinatorial chemistry and molecular biology.Organic base: An organic base is an organic compound which acts as a base. Organic bases are usually, but not always, proton acceptors.Metals in medicine: Metals in medicine are used in organic systems for diagnostic and treatment purposes. Inorganic elements are also essential for organic life as cofactors in enzymes called Metalloproteins.Metallofullerene: In chemistry, a metallofullerene is a molecule composed of a metal atom trapped inside a fullerene cage.Ligand (biochemistry): In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. In protein-ligand binding, the ligand is usually a signal-triggering molecule binding to a site on a target protein.Electrophilic substitution of unsaturated silanes: Electrophilic substitution of unsaturated silanes involves attack of an electrophile on an allyl- or vinylsilane. An allyl or vinyl group is incorporated at the electrophilic center after loss of the silyl group.Molecular Foundry: thumbnail|200px|The Molecular Foundry building in Berkeley, CaliforniaPhase problem: In physics the phase problem is the name given to the problem of loss of information concerning the phase that can occur when making a physical measurement. The name itself comes from the field of x-ray crystallography, where the phase problem has to be solved for the determination of a structure from diffraction data.The Flash ChroniclesColes PhillipsEcotoxicology: Ecotoxicology is the study of the effects of toxic chemicals on biological organisms, especially at the population, community, ecosystem level. Ecotoxicology is a multidisciplinary field, which integrates toxicology and ecology.Ferrocene-containing dendrimersCarbon–carbon bond: A carbon–carbon bond is a covalent bond between two carbon atoms. The most common form is the single bond: a bond composed of two electrons, one from each of the two atoms.Alkaliphile: Alkaliphiles are a class of extremophilic microbes capable of survival in alkaline (pH roughly 8.5-11) environments, growing optimally around a pH of 10.Palladium(II) chlorideSEA Native Peptide LigationMcLafferty rearrangement: The McLafferty rearrangement is a reaction observed in mass spectrometry. It is sometimes found that a molecule containing a keto-group undergoes β-cleavage, with the gain of the γ-hydrogen atom.Fluorescent glucose biosensor: Fluorescent glucose biosensors are devices that measure the concentration of glucose in diabetic patients by means of sensitive protein that relays the concentration by means of fluorescence, an alternative to amperometric sension of glucose. No device has yet entered the medical market,No fluorescent biosensor has yet entered the medical market, however, in the market for research tools several fluorescent biosensors are present, such as a kit using [Vibrio fischeri] but, due to the prevalence of diabetes, it is the prime drive in the construction of fluorescent biosensors.Silicene: Silicene is a two-dimensional allotrope of silicon, with a hexagonal honeycomb structure similar to that of graphene.Valence electron: In chemistry, a valence electron is an electron that is associated with an atom, and that can participate in the formation of a chemical bond; in a single covalent bond, both atoms in the bond contribute one valence electron in order to form a shared pair. The presence of valence electrons can determine the element's chemical properties and whether it may bond with other elements: For a main group element, a valence electron can only be in the outermost electron shell.Standard enthalpy of formation: The standard enthalpy of formation or standard heat of formation of a compound is the change of enthalpy during the formation of 1 mole of the compound from its constituent elements, with all substances in their standard states at 1 atmosphere (1 atm or 101.3 kPa).Polyvalent DNA gold nanoparticles: Polyvalent DNA gold nanoparticles are colloidal gold whose surface is modified with thiol capped synthetic DNA sequences. They were co-discovered by Chad Mirkin et al.Lattice protein: Lattice proteins are highly simplified computer models of proteins which are used to investigate protein folding.Fluorescent tag: In molecular biology and biotechnology, a fluorescent tag, also known as a label or probe, is a molecule that is attached chemically to aid in the labeling and detection of a biomolecule such as a protein, antibody, or amino acid. Generally, fluorescent tagging, or labeling, uses a reactive derivative of a fluorescent molecule known as a fluorophore.DNA condensation: DNA condensation refers to the process of compacting DNA molecules in vitro or in vivo. Mechanistic details of DNA packing are essential for its functioning in the process of gene regulation in living systems.Arteriovenous oxygen difference: The arteriovenous oxygen difference, or a-vO2 diff, is the difference in the oxygen content of the blood between the arterial blood and the venous blood. It is an indication of how much oxygen is removed from the blood in capillaries as the blood circulates in the body.DNA binding site: DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that (1) they are part of a DNA sequence (e.Bipolar electrochemistry: Bipolar electrochemistry is a phenomenon in electrochemistry based on the polarization of conducting objects in electric fields. Indeed, this polarization generates a potential difference between the two extremities of the substrate that is equal to the electric field value multiplied by the size of the object.
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