Cell death
Apoptosis or Type I cell-death, and autophagy or Type II cell-death are both forms of programmed cell death, while necrosis is ... "non-apoptotic programmed cell-death" (or "caspase-independent programmed cell-death"), these alternative routes to death are as ... Ischemic cell death, or oncosis, is a form of accidental, or passive cell death that is often considered a lethal injury. The ... Activation-induced cell death (AICD) is a programmed cell death caused by the interaction of Fas receptor (Fas, CD95)and Fas ...
Programmed cell death
... (PCD; sometimes referred to as cellular suicide) is the death of a cell as a result of events inside of a ... Cell death in arthropods occurs first in the nervous system when ectoderm cells differentiate and one daughter cell becomes a ... Apoptosis and Cell Death Labs International Cell Death Society The Bcl-2 Family Database (Webarchive template wayback links, ... Apoptosis and autophagy are both forms of programmed cell death. Necrosis is the death of a cell caused by external factors ...
Cell Death & Differentiation
... is a peer-reviewed academic journal published by Nature Research. BIOBASE/Current Awareness in ...
Immunogenic cell death
... is any type of cell death eliciting an immune response. Both accidental cell death and regulated cell ... March 2018). "Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018". Cell Death ... The name 'immunogenic cell death' is also used for one specific type of regulated cell death that initiates an immune response ... Immunogenic cell death contrasts to forms of cell death (apoptosis, autophagy or others) that do not elicit any response or ...
Ischemic cell death
... , or oncosis, is a form of accidental cell death. The process is characterized by an ATP depletion within ... Apoptosis, or programmed cell death involves a series of cell shrinking processes, beginning with cell size reduction and ... Cell Death & Differentiation, 5(7), 563-568. Ren, Y., & Savill, J. (1998). Apoptosis: the importance of being eaten. Cell Death ... In stage two, the reversibility threshold for the cell is passed and the cell becomes committed to cell death. During this ...
Identification of cell death
"Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009". Cell Death and Differentiation ... Programmed cell death means genetic control of the process, thus genes specifying cell death in a developmental sequence must ... Standards for the identification of cell death have changed. Cell death used to be defined and described based on morphology. ... A set of recommendations for describing the terminology of cell death was proposed by the Nomenclature Committee on Cell Death ...
Activation-induced cell death
2000), Activation-induced cell death in B lymphocytes. Cell Res. 10(3):179-92 Nagata S. (1997), Apoptosis by death factor. Cell ... AICD (activation-induced cell death) is programmed cell death caused by the interaction of Fas receptors (Fas, CD95) and Fas ... Activation-Induced Cell Death in T Cells and Autoimmunity. Cell Mol Immunol. 1(3):186-92 Kabelitz D, Janssen O. (1997), Antigen ... 2:d61-77 Green DR, Droin N, Pinkoski M. (2003), Activation-induced cell death in T cells. Immunol Rev. 193:70-81 Donjerković D ...
Cell 2455 Death Row
Wikiquote has quotations related to Cell 2455 Death Row. Cell 2455, Death Row at IMDb Cell 2455, Death Row at the TCM Movie ... Cell 2455, Death Row: A Condemned Man's Own Story is a 1954 memoir that is the first of four books written on death row by ... Before he was executed in 1960, he was the longest-lived death row inmate in modern history. Chessman began writing his memoir ... Ulin, David L. (19 September 2006). "Caryl Chessman's infamous death row case is revisited". Los Angeles Times. Retrieved 5 ...
Cell 2455 Death Row (film)
Wikiquote has quotations related to Cell 2455 Death Row (film). Cell 2455, Death Row at IMDb Cell 2455, Death Row at the TCM ... Cell 2455, Death Row is a 1955 American crime film noir directed by Fred F. Sears and starring William Campbell and Robert ... Howard Wright as Judge Columbia Pictures acquired the rights to Caryl Chessman's book Cell 2455, Death Row: A Condemned Man's ... A death row inmate uses his prison-law studies to fight for his life. William Campbell as Whit Whittier R. Wright Campbell as ...
Programmed cell death protein 1
... programmed cell death) of antigen-specific T-cells in lymph nodes. Second, it reduces apoptosis in regulatory T cells (anti- ... PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells. PD- ... and on T cells and B cells upon TCR and B cell receptor signaling, whereas in resting mice, PD-L1 mRNA can be detected in the ... Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein on the surface of ...
Endothelial cell tropism
... focus on cell death". Cell Death & Differentiation. 22 (8): 1250-1259. doi:10.1038/cdd.2015.67. ISSN 1476-5403. PMC 4495366. ... In cell-based, high-throughput drug screening, cell tropism is an important consideration during cell type selection. The cell ... While endothelial cells are not the major cell type Dengue targets, the virus binds to various cell surface receptors on ... Like other cells, the endothelial cell possesses several features that supports a productive viral infection a cell including, ...
Cell cycle withdrawal
... the cell cycle withdrawal ensures that these aged cells are not divided into other daughter cells before death, so as to ... Not all cells carry out cell cycle withdrawal. In some cells, such as germ cells, stem cells and white blood cells, the ... Cell cycle withdrawal refers to the natural stoppage of cell cycle during cell division. When cells divide, there are many ... This prevents cells from cell dividing, withdrawing cells from the cell division cycle. Therefore, telomeres act as the buffer ...
Th22 cell
"B cells control lupus autoimmunity by inhibiting Th17 and promoting Th22 cells". Cell Death & Disease. 11 (3): 164. doi:10.1038 ... Th22 cells (T helper cells type 22) are subpopulation of CD4+ T cells that produce interleukin-22 (IL-22). They play a role in ... Th22 cells are mainly defined by their high secretion of interleukin-22 (IL-22). Besides IL-22, Th22 cells also produce other ... It seems that Th22 cells could play a protective role in patients with AIDS. CCR5 and α4β7 molecules expressed by Th22 cells ...
Type 3 innate lymphoid cells
Cell Death & Disease. 10 (4): 315. doi:10.1038/s41419-019-1540-2. PMC 6453898. PMID 30962426. Pavlova A, Sharafutdinov I ( ... This is supported by the fact that ILC3 cells mirror the phenotype of Th17 cells, and a subset of ILC3 cells has also been ... August 2018). "Innate Lymphoid Cells: 10 Years On". Cell. 174 (5): 1054-1066. doi:10.1016/j.cell.2018.07.017. PMID 30142344. ... including cells lysis and secretion of pro-inflammatory cytokines. LTi cells (lymphoid tissue-inducing cells) are a ...
Tumor-associated endothelial cell
Cell Death Discovery. 1: 15064. doi:10.1038/cddiscovery.2015.64. ISSN 2058-7716. PMC 4979496. PMID 27551488. Cook, Kristina M ... Tumor-associated endothelial cells or tumor endothelial cells (TECs) refers to cells lining the tumor-associated blood vessels ... These tumor-associated endothelial cells have been found to over-express the endothelin B receptor, which suppresses T-cell ... De Val, Sarah; Black, Brian L. (2009-02-01). "Transcriptional control of endothelial cell development". Developmental Cell. 16 ...
Hematopoietic stem cell
When provoked by cell death or damage, Hematopoietic stem cells exit quiescence and begin actively dividing again. The ... Lymphoid cells include T cells, B cells, natural killer cells, and innate lymphoid cells. The definition of hematopoietic stem ... Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells. This process is called haematopoiesis. ... Balanced (Bala) Hematopoietic stem cells repopulate peripheral white blood cells in the same ratio of myeloid to lymphoid cells ...
Bleb (cell biology)
During apoptosis (programmed cell death), the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These ... Blebs have been seen in cultured cells in certain stages of the cell cycle. These blebs are used for cell locomotion in ... Paluch EK, Raz E (October 2013). "The role and regulation of blebs in cell migration". Current Opinion in Cell Biology. Cell ... Paluch EK, Raz E (October 2013). "The role and regulation of blebs in cell migration". Current Opinion in Cell Biology. Cell ...
Cancer stem cell
... cancer could regress due to differentiation and/or cell death.[citation needed] The fraction of tumor cells that are CSCs and ... "Critical appraisal of the side population assay in stem cell and cancer stem cell research". Cell Stem Cell. 8 (2): 136-47. doi ... These resulting mesenchymal cells have properties of cancer stem cells. In breast cancer CD44+CD24−/low cells are detectable in ... They examined cancer stem cell plasticity in which cancer stem cells can transition between non-cancer stem cells (Non-CSC) and ...
Red blood cell
This process is termed eryptosis, red blood cell programmed death. This process normally occurs at the same rate of production ... Red blood cells in mammals are anucleate when mature, meaning that they lack a cell nucleus. In comparison, the red blood cells ... Red blood cells are deformable, flexible, are able to adhere to other cells, and are able to interface with immune cells. Their ... Red blood cells are cells present in blood to transport oxygen. The only known vertebrates without red blood cells are the ...
HCT116 cells
Cell Death and Disease. 8 (7): e2957. doi:10.1038/cddis.2017.347. PMC 5584615. PMID 28749466. Gu, Chunfang (27 October 2016). " ... HCT116 is a human colon cancer cell line used in therapeutic research and drug screenings. HCT116 cells have a mutation in ... The HCT116 cell line was found to have two variations; one with a large expression of the Insp8 gene, and the other without. ... The cell line has been used in tumorigenicity studies, along with other research that has shown that Cyclin D1 holds large ...
Mesenchymal stem cell
"Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression". Stem Cells. 35 ( ... May 2012). "Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis". Cell Stem Cell ... bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow ... Ma S, Xie N, Li W, Yuan B, Shi Y, Wang Y (February 2014). "Immunobiology of mesenchymal stem cells". Cell Death and ...
B-cell maturation antigen
June 2005). "Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation". Cell Death and ... TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). Serum B- ... 2019-11-13). "Results from CARTITUDE-1: A Phase 1b/2 Study of JNJ-4528, a CAR-T Cell Therapy Directed Against B-Cell Maturation ... B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a ...
Fas receptor
The Fas receptor is a death receptor on the surface of cells that leads to programmed cell death (apoptosis) if it binds its ... This allows the adaptor molecule FADD to bind the death domain of Fas through its own death domain. FADD also contains a death ... the induction of bystander tumor cell death even amongst cognate antigen non-expressing (bystander) cells. CTL-mediated ... Nagata S (July 2004). "Early work on the function of CD95, an interview with Shige Nagata". Cell Death and Differentiation. 11 ...
Superfamily database
Intra-cellular processes: cell motility and division; cell death; intra-cellular transport; secretion. Extra-cellular processes ... Metabolism: Anabolic and catabolic processes; cell maintenance and homeostasis; secondary metabolism. ... inter-, extr-cellular processes like cell adhesion; organismal process like blood clotting or the immune system. General: ...
Urinary cell-free DNA
10 December 2008). Programmed Cell Death in Protozoa. Springer. ISBN 978-0-387-76717-8. OCLC 1134822635. Kafwabulula, M.; Ahmed ... Urinary cell-free DNA (ucfDNA) refers to DNA fragments in urine released by urogenital and non-urogenital cells. Shed cells on ... Most ucfDNA is derived from urogenital tract cells. Approximately over 3×106 urogenital tract cells are exfoliated into urine ... They are separated together with cell debris by centrifugation of urine and they represent the genome of the originated cells. ...
Cell fate determination
These processes include cell proliferation, differentiation, cellular movement and programmed cell death. Each cell in an ... two of which are by the combination of transcription factors the cells have and by the cell-cell interaction. Cells' fate ... If a cell is in a determined state, the cell's fate cannot be reversed or transformed. In general, this means that a cell ... Eur J Cell Biol 2010, 89:225-230. Lau, S.; Ehrismann, J.; Schlereth, A.; Takada, S.; Mayer, U.; Jürgens, G. (2010). "Cell-cell ...
Condemn cell
A Condemn Cell, also known as a Death Row Cell, is a designated room within a prison where individuals who have been sentenced ... "Living death in condemn cells". theindependentbd.com. Retrieved 2023-07-05. Staff Correspondent (2022-04-06). "Why inmates on ... Typically, a condemn cell can house between one and three inmates. The use of Condemn Cells and capital punishment itself ... There have been instances where acquitted people have been confined in condemn cells, for multiple years. condemned-cell noun ...
BUB1
Jeganathan K, Malureanu L, Baker DJ, Abraham SC, van Deursen JM (Oct 2007). "Bub1 mediates cell death in response to chromosome ... Kitagawa K, Niikura Y (Apr 2008). "Caspase-independent mitotic death (CIMD)". Cell Cycle. 7 (8): 1001-5. doi:10.4161/cc.7.8. ... In vitro knockdown of Bub1 in p53 impaired cells (e.g. HeLa cells) caused aneuploidy. Whether aneuploidy alone is a sufficient ... Cell. 32 (3): 394-405. doi:10.1016/j.molcel.2008.09.017. PMC 2644263. PMID 18995837. UniProt: O43683 "BUB1 protein (Homo ...
NOL3
... and causes cell death in cultured cells". J. Biol. Chem. 275 (4): 2647-53. doi:10.1074/jbc.275.4.2647. PMID 10644725. Li PF, Li ... "Calcium binding of ARC mediates regulation of caspase 8 and cell death". Mol. Cell. Biol. 24 (22): 9763-70. doi:10.1128/MCB. ... "Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions". Mol. Cell. 15 (6 ... Cell Death Differ. 12 (6): 682-6. doi:10.1038/sj.cdd.4401631. PMID 15861191. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T ...
NOX4
"Nox4-dependent ROS modulation by amino endoperoxides to induce apoptosis in cancer cells". Cell Death Dis. 4 (3): e552. doi: ... 2002). "An NAD(P)H oxidase regulates growth and transcription in melanoma cells". Am. J. Physiol., Cell Physiol. 282 (6): C1212 ... Cell. Biol. 24 (5): 1844-54. doi:10.1128/MCB.24.5.1844-1854.2004. PMC 350558. PMID 14966267. Chamulitrat W, Stremmel W, ... Cell. Biol. 24 (24): 10703-17. doi:10.1128/MCB.24.24.10703-10717.2004. PMC 533993. PMID 15572675. Djordjevic T, BelAiba RS, ...