Casein kinase 2
Xu X, Toselli PA, Russell LD, Seldin DC (September 1999). "Globozoospermia in mice lacking the casein kinase II alpha' ... CSNK2A1 CSNK2A2 Casein kinase 1 - a distinct protein kinase family Ahmad KA, Wang G, Unger G, Slaton J, Ahmed K (2008). " ... Casein kinase 2 (EC 2.7.11.1)(CK2/CSNK2) is a serine/threonine-selective protein kinase that has been implicated in cell cycle ... Schwein PA, Ge Y, Yang B, D'Souza A, Mody A, Shen D, Woo CM (May 2022). "Writing and Erasing O-GlcNAc on Casein Kinase 2 Alpha ...
Casein kinase 2, alpha 1
Casein kinase II subunit alpha is an enzyme that in humans is encoded by the CSNK2A1 gene. Casein kinase II is a serine/ ... "Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit ... Yamaguchi Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H (August 1998). "Casein kinase II interacts with the bZIP domains ... Three transcript variants encoding two different proteins have been found for this gene. Casein kinase 2, alpha 1 has been ...
Casein kinase 1
Yang Y, Cheng P, Liu Y (April 2002). "Regulation of the Neurospora circadian clock by casein kinase II". Genes & Development. ... "casein kinase 1 alpha" and "casein kinase 1 epsilon". Casein kinase 1 epsilon has been suggested to play a role in ... In humans there are three casein kinase 1 gamma enzymes. Xenopus casein kinase 1 gamma (CK1gamma) is associated with the cell ... "A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of ...
Casein kinase 1, alpha 1
Zhang Y, Qiu WJ, Chan SC, Han J, He X, Lin SC (May 2002). "Casein kinase I and casein kinase II differentially regulate axin ... Casein kinase I isoform alpha is an enzyme that in humans is encoded by the CSNK1A1 gene. Casein kinase 1, alpha 1 has been ... Casein kinase 1 GRCh38: Ensembl release 89: ENSG00000113712 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000024576 ... Dubois T, Howell S, Zemlickova E, Aitken A (Apr 2002). "Identification of casein kinase Ialpha interacting protein partners". ...
Casein kinase 1 isoform epsilon
Zhang Y, Qiu WJ, Chan SC, Han J, He X, Lin SC (May 2002). "Casein kinase I and casein kinase II differentially regulate axin ... The protein encoded by the casein kinase 1 epsilon gene is a serine/threonine protein kinase and a member of the casein kinase ... Casein kinase 1 epsilon, and related casein kinase 1 delta, is dephosphorylated in this pathway. Dephosphorylation of casein ... The current theory for how casein kinase 1 epsilon and/or casein kinase 1 delta function in this pathway is that both casein ...
EEF1B2
Phosphorylation by casein kinase II". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1264 (3): 303-11. ... Sheu GT, Traugh JA (Jan 1999). "A structural model for elongation factor 1 (EF-1) and phosphorylation by protein kinase CKII". ... Subunit interactions, elongation activity, and phosphorylation by protein kinase CKII". The Journal of Biological Chemistry. ... "Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". ...
Progesterone receptor
In vitro phosphorylation by casein kinase II". The Journal of Biological Chemistry. 269 (49): 31034-40. doi:10.1016/S0021-9258( ... "Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone ... "Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone ... In humans, PR is encoded by a single PGR gene residing on chromosome 11q22, it has two isoforms, PR-A and PR-B, that differ in ...
BRCA1
O'Brien KA, Lemke SJ, Cocke KS, Rao RN, Beckmann RP (July 1999). "Casein kinase 2 binds to and phosphorylates BRCA1". Biochem. ... two quartets of cysteine or histidine residues that coordinate two zinc atoms. This motif contains a short anti-parallel beta- ... "BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3". ... kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment ...
Myc
Lüscher B, Kuenzel EA, Krebs EG, Eisenman RN (April 1989). "Myc oncoproteins are phosphorylated by casein kinase II". The EMBO ... "Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase". Proceedings of the National ... Gupta S, Davis RJ (October 1994). "MAP kinase binds to the NH2-terminal activation domain of c-Myc". FEBS Letters. 353 (3): 281 ... Iijima S, Teraoka H, Date T, Tsukada K (June 1992). "DNA-activated protein kinase in Raji Burkitt's lymphoma cells. ...
SMIM19
Casein kinase 2 can play a role in cell cycle regulation, DNA repair, and necessary for cell survival; down-regulation of ... "PSORT II Prediction". psort.hgc.jp. Retrieved 2020-12-19. "PSICQUIC View". www.ebi.ac.uk. Retrieved 2020-12-19. "AceView: Gene: ... Casein kinase 2 can promote tumorigenesis. Protein kinase C is a protein-regulator and is highly involved in various signaling ... SNPs 16-2 are found in the transmembrane region of SMIM19. GRCh38: Ensembl release 89: ENSG00000176209 - Ensembl, May 2017 ...
Thymosin α1
1992). "Prothymosin alpha is phosphorylated by casein kinase-2". FEBS Lett. 312 (2-3): 152-6. doi:10.1016/0014-5793(92)80924-6 ... 1992). "Prothymosin alpha enhances human and murine MHC class II surface antigen expression and messenger RNA accumulation". J ... 85 (2-5): 117-22. doi:10.1016/S0960-0760(03)00207-3. PMID 12943695. S2CID 32374864. Barcia MG, Castro JM, Jullien CD, et al. ( ... 292 (2): 70-4. doi:10.1056/NEJM197501092920204. PMID 1078552. Garaci E, Favalli C, Pica F, et al. (September 2007). "Thymosin ...
Nucleolin
Li D, Dobrowolska G, Krebs EG (Jun 1996). "The physical association of casein kinase 2 with nucleolin". The Journal of ... Parada CA, Roeder RG (Jul 1999). "A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription". ... Li D, Dobrowolska G, Krebs EG (Jun 1996). "The physical association of casein kinase 2 with nucleolin". The Journal of ... Jordan P, Heid H, Kinzel V, Kübler D (Dec 1994). "Major cell surface-located protein substrates of an ecto-protein kinase are ...
Gap-43 protein
Apel ED, Litchfield DW, Clark RH, Krebs EG, Storm DR (Jun 1991). "Phosphorylation of neuromodulin (GAP-43) by casein kinase II ... It is a major protein kinase C (PKC) substrate and is considered to play a key role in neurite formation, regeneration, and ... Chao S, Benowitz LI, Krainc D, Irwin N (Sep 1996). "Use of a two-hybrid system to investigate molecular interactions of GAP-43 ... However, F1 was not cAMP kinase dependent. B-50 was regulated by the pituitary peptide ACTH and was associated with grooming ...
Hp53int1
There is a possible Casein Kinase II phosphorylation site between amino acids 22-25. Casein Kinase II phosphorylation is ... its casein kinase II phosphorylation site, and its ubiquitous expression across tissues. The Hp53int1 gene expression is ... and protein-tyrosine kinase). There are two identified SNPS for Hp53int1. SNP 15 falls at position 32 in a sequence of 43 ... "GPS 5.0 - Kinase-specific Phosphorylation Site Prediction". gps.biocuckoo.cn. Retrieved 2022-12-16. "Motif Scan". myhits.sib. ...
ARR3
Kim YM, Barak LS, Caron MG, Benovic JL (2002). "Regulation of arrestin-3 phosphorylation by casein kinase II". J. Biol. Chem. ... 224 (1-2): 87-95. doi:10.1016/S0378-1119(98)00510-1. PMID 9931451. John SK, Smith JE, Aguirre GD, Milam AH (2000). "Loss of ... 204 (1-2): 127-40. doi:10.1016/S0303-7207(03)00088-1. PMID 12850288. S2CID 25222855. Zhu X, Brown B, Li A, et al. (2003). "GRK1 ... 382 (1-2): 105-10. doi:10.1016/0014-5793(96)00163-9. PMID 8612728. ter Haar E, Musacchio A, Harrison SC, Kirchhausen T (1998 ...
AP3B1
Kim YM, Barak LS, Caron MG, Benovic JL (May 2002). "Regulation of arrestin-3 phosphorylation by casein kinase II". The Journal ... Dubois T, Howell S, Zemlickova E, Aitken A (Apr 2002). "Identification of casein kinase Ialpha interacting protein partners". ... 15 (2): 575-87. doi:10.1091/mbc.E03-06-0401. PMC 329249. PMID 14657250. Guinn BA, Bland EA, Lodi U, Liggins AP, Tobal K, ... 8 (2): 323-30. doi:10.1093/hmg/8.2.323. PMID 9931340. Dell'Angelica EC, Shotelersuk V, Aguilar RC, Gahl WA, Bonifacino JS (Jan ...
TEDDM1
... a casein kinase II phosphorylation site, a Leucine zipper pattern, two N-myristylation sites, and three protein kinase C ... Casein kinase II is involved with protein stability and cell signaling response. Leucine zippers are sequence motifs that ... Litchfield DW, Lüscher B (November 1993). Khandelwal RL, Wang JH (eds.). "Casein kinase II in signal transduction and cell ... TEDDM1 has two known paralogs, TMEM45A and TMEM45B. Over 100 orthologs exist for human gene TEDDM1. Of these known orthologs ...
CCDC113
CSNK2A2 the casein kinase 2, alpha prime polypeptide contains a protein kinase domain and a catalytic domain. GINS3 is ... Interacting proteins found using two-hybrid screening techniques include GIT1; a G protein-coupled receptor kinase interacting ... "CSNK2A2 casein kinase 2, alpha prime polypeptide [ Homo sapiens (human) ]". NCBI. Retrieved May 8, 2013. "GINS3 GINS complex ... Two point mutations have also been linked to adenocarcinomas of the rectum, a missense mutation of R361Q and a base pair point ...
DNA damage-inducible transcript 3
Ubeda M, Habener JF (October 2003). "CHOP transcription factor phosphorylation by casein kinase 2 inhibits transcriptional ... which then activates the downstream kinases, Jun-N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38 MAPK), ... Those processes are mainly regulated by three factors: protein kinase RNA-like endoplasmic reticulum kinase (PERK), activating ... double-stranded RNA-activated protein kinase (PKR) iron deficiency through heme-regulated inhibitor kinase (HRI) stress from ...
Globozoospermia
Xu, X.; Toselli, P. A.; Russell, L. D.; Seldin, D. C. (1999-09-01). "Globozoospermia in mice lacking the casein kinase II alpha ... There are two types of globozoospermia: Type 1 globozoospermia exhibits a complete lack of acrosome and acrosomal enzymes and ... however it is unclear whether these two forms are variations on the same syndrome, or actually different syndromes. Infertility ... doi:10.1007/s10815-015-0433-2. ISSN 1058-0468. PMC 4380889. PMID 25711835. Dam, A. H. D. M.; Feenstra, I.; Westphal, J. R.; ...
Nucleolar phosphoprotein p130
Li D, Meier UT, Dobrowolska G, Krebs EG (1997). "Specific interaction between casein kinase 2 and the nucleolar protein Nopp140 ... Pai CY, Yeh NH (1996). "Cell proliferation-dependent expression of two isoforms of the nucleolar phosphoprotein p130". Biochem ... Chiu CM, Tsay YG, Chang CJ, Lee SC (2002). "Nopp140 is a mediator of the protein kinase A signaling pathway that activates the ... 142 (2): 319-29. doi:10.1083/jcb.142.2.319. ISSN 0021-9525. PMC 2133063. PMID 9679133. Miau, L H; Chang C J; Shen B J; Tsai W H ...
JADE1
... is a target of phosphorylation by Casein kinase 2 (CK2). In addition, multiple phosphorylation sites are found by high ... Two resultant protein products of the JADE1 gene were designated JADE1S for the short (which is same as(3)) and JADE1L for the ... "Casein kinase 1 α phosphorylates the Wnt regulator Jade-1 and modulates its activity". The Journal of Biological Chemistry. 289 ... There are two known protein products of the PHF17 gene, the full length JADE1 (JADE1L) and its splice variant missing the C- ...
Calsequestrin
Cala SE, Jones LR (January 1991). "Phosphorylation of cardiac and skeletal muscle calsequestrin isoforms by casein kinase II. ... Both forms of calsequestrin are phosphorylated by casein kinase 2, but the cardiac form is phosphorylated more rapidly and to a ... Two forms of calsequestrin have been identified. The cardiac form Calsequestrin-2 (CASQ2) is present in cardiac and slow ... In addition, the hydrophobic core of domain II appears to be necessary for CASQ2's function, because a single amino acid ...
STARD10
Casein kinase II phosphorylates the protein on its serine at position 184. The function of StarD10 in the cell is not yet ... "Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity". The Journal of Biological ... "Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity". The Journal of Biological ... 3.0.CO;2-P. PMID 9610721. "Entrez Gene: STARD10 START domain containing 10". Olayioye MA, Vehring S, Müller P, Herrmann A, ...
LIG1
... and Ser91 by cyclin-dependent kinase (CDK) and Ser66 by casein kinase II (CKII). Phosphorylation of these residues (Ser66 in ... "Activation of mammalian DNA ligase I through phosphorylation by casein kinase II". The EMBO Journal. 11 (8): 2925-33. doi: ... "Cell cycle-dependent phosphorylation of human DNA ligase I at the cyclin-dependent kinase sites". The Journal of Biological ... 282 (2): e1-e3. doi:10.1016/S0021-9258(20)73504-0. Ferrari G, Rossi R, Arosio D, Vindigni A, Biamonti G, Montecucco A ( ...
HNRNPA2B1
HNRPA2B1 has been shown to interact with casein kinase 2, alpha 1. The mutation p.D290V/302V in hnRNPA2B1 is implicated in ... The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to ... Bauw G, Rasmussen HH, van den Bulcke M, van Damme J, Puype M, Gesser B, Celis JE, Vandekerckhove J (1990). "Two-dimensional gel ... Biamonti G, Ruggiu M, Saccone S, Della Valle G, Riva S (August 1994). "Two homologous genes, originated by duplication, encode ...
Glial cell line-derived neurotrophic factor
Yamaguchi Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H (August 1998). "Casein kinase II interacts with the bZIP domains ... It can also activate Src-family kinases through its GFRα1 receptor. The most prominent feature of GDNF is its ability to ... The association between GDNF and NCAM results in the activation of cytoplasmic protein tyrosine kinases Fyn and FAK. GDNF has ... June 1996). "GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF ...
Activating transcription factor 2
Yamaguchi Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H (August 1998). "Casein kinase II interacts with the bZIP domains ... "Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase". Proc. Natl. Acad. Sci. U.S.A. 94 ( ... a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase ... Casein kinase 2, alpha 1, CREB binding protein, CSNK2A2, JDP2, MAPK14, MAPK8, Mothers against decapentaplegic homolog 3 NCOA6, ...
Epithelial-mesenchymal transition
2017). "Casein Kinase II (CK2) as a Therapeutic Target for Hematological Malignancies". Current Pharmaceutical Design. 23 (1): ... Two mathematical models have been proposed, attempting to explain the emergence of this hybrid E/M phenotype, and its highly ... Zou J, Luo H, Zeng Q, Dong Z, Wu D, Liu L (June 2011). "Protein kinase CK2α is overexpressed in colorectal cancer and modulates ... Silmitasertib (CX-4945) is a small molecule inhibitor of protein kinase CK2, which has been supported to be linked with TGF-β ...
60S ribosomal protein L5
Kim JM, Cha JY, Marshak DR, Bae YS (1996). "Interaction of the beta subunit of casein kinase II with the ribosomal protein L5 ... Kim JM, Cha JY, Marshak DR, Bae YS (September 1996). "Interaction of the beta subunit of casein kinase II with the ribosomal ... The protein interacts specifically with the beta subunit of casein kinase 2. Variable expression of this gene in colorectal ... Boldyreff B, Issinger OG (February 1997). "A-Raf kinase is a new interacting partner of protein kinase CK2 beta subunit". FEBS ...