... carnitine acetyl coenzyme A transferase, carnitine acetylase, carnitine acetyltransferase, carnitine-acetyl-CoA transferase, ... Carnitine O-acetyltransferase also called carnitine acetyltransferase (CRAT, or CAT) (EC 2.3.1.7) is an enzyme that encoded by ... carnitine O-acetyltransferase. Other names in common use include acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine ... "Entrez Gene: CRAT carnitine acetyltransferase". McGarry JD, Brown NF (Feb 1997). "The mitochondrial carnitine ...

... has also been shown by NMR to bind to carnitine acetyltransferase. Carnitine acetyltransferase belongs to a family of ... The co-A is then exchanged with carnitine (via the enzyme carnitine palmitoyltransferase I) to produce a fatty acid-carnitine ... Meldonium is a relatively weak inhibitor to carnitine acetyltransferase (when compared to γ-butyrobetaine hydroxylase), with an ... December 2009). "Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism". Journal of Enzyme ...

Enzyme-coupled method have also been applied to detect carnitine formation, by using the enzyme carnitine acetyltransferase and ... Parvin R, Pande SV (1976). "Microdetermination of (−)carnitine and carnitine acetyltransferase activity". Anal. Biochem. 79 (1- ... Carnitine Mildronate Carnitine biosynthesis Beta Oxidation Fatty acid metabolism Stevens rearrangement GRCh38: Ensembl release ... the last step in the L-carnitine biosynthesis pathway. Carnitine is essential for the transport of activated fatty acids across ...

Valkner, K. J.; Bieber, L. L. (1982-07-14). "The sidedness of carnitine acetyltransferase and carnitine octanoyltransferase of ... In the absence of carnitine acetyltransferase (CRAT), acyltransferases such as CROT can catalyze the acetyl group transfer from ... Carnitine O-octanoyltransferase (CROT or COT) is a member of the transferase family, more specifically a carnitine ... Other names in common use include medium-chain/long-chain carnitine acyltransferase, carnitine medium-chain acyltransferase, ...

2003). "Structure of Human Carnitine Acetyltransferase: Molecular Basis For Fatty Acyl Transfer". J Biol Chem. 278 (15): 13159- ... Carnitine O-palmitoyltransferase Carnitine palmitoyltransferase I deficiency Fasciculation Myokymia Primary carnitine ... The "carnitine shuttle" is composed of three enzymes that utilize carnitine to facilitate the import of hydrophobic long-chain ... Longo N, Amat, San Filippo C, Pasquali M (2006). "Disorders of Carnitine Transport and the Carnitine Cycle". Am J Med Genet C ...

One such mechanism based upon a carnitine acetyltransferase model is shown below in which the His 473 deprotonates carnitine ... Carnitine palmitoyltransferase I (CPT1) also known as carnitine acyltransferase I, CPTI, CAT1, CoA:carnitine acyl transferase ( ... such as carnitine acetyltransferase (CRAT). An important structural difference between CPT1 and CPT2, CRAT and carnitine ... "Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal". The Biochemical Journal ...

"Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport". Cell. ... Carnitine O-palmitoyltransferase (also called carnitine palmitoyltransferase) is a mitochondrial transferase enzyme (EC 2.3. ... A related transferase is carnitine acyltransferase. Palmitoylcarnitine Palmitoyl CoA There are four different forms of CPT in ... PDOC00402 - Acyltransferases ChoActase / COT / CPT family in PROSITE Choline/Carnitine o-acyltransferase family[permanent dead ...

3-Hydroxyisovaleryl CoA is likely detoxified by carnitine acetyltransferase producing 3HIA-carnitine, which is transported ... The transfer to carnitine by 4 carnitine acyl-CoA transferases distributed in subcellular compartments likely serves as an ... 3HIA-carnitine is thought to be either directly deacylated by a hydrolase to 3HIA or to undergo a second CoA exchange to again ... "Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in ...

3-Hydroxyisovaleryl CoA is likely detoxified by carnitine acetyltransferase producing 3HIA-carnitine, which is transported ... The transfer to carnitine by 4 carnitine acyl-CoA transferases distributed in subcellular compartments likely serves as an ... 3HIA-carnitine is thought to be either directly deacylated by a hydrolase to 3HIA or to undergo a second CoA exchange to again ... "Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in ...

3-Hydroxyisovaleryl CoA is likely detoxified by carnitine acetyltransferase producing 3HIA-carnitine, which is transported ... The transfer to carnitine by 4 carnitine acyl-CoA transferases distributed in subcellular compartments likely serves as an ... 3HIA-carnitine is thought to be either directly deacylated by a hydrolase to 3HIA or to undergo a second CoA exchange to again ... "Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in ...

Esfahan and Tabriz Confédération Syndicale du Congo Catapult C Synthesis Carnitine O-acetyltransferase, an enzyme CATC AB, A ...

... cleavage enzyme Protein tyrosine phosphatase Carnitine O-palmitoyltransferase Carnitine O-acetyltransferase Carnitine O- ...

... arylamine N-acetyltransferase EC 2.3.1.6: choline O-acetyltransferase EC 2.3.1.7: carnitine O-acetyltransferase EC 2.3.1.8: ... D-tryptophan N-acetyltransferase EC 2.3.1.35: glutamate N-acetyltransferase EC 2.3.1.36: D-amino-acid N-acetyltransferase EC ... amino-acid N-acetyltransferase EC 2.3.1.2: imidazole N-acetyltransferase EC 2.3.1.3: glucosamine N-acetyltransferase EC 2.3.1.4 ... glycine C-acetyltransferase EC 2.3.1.30: serine O-acetyltransferase EC 2.3.1.31: homoserine O-acetyltransferase EC 2.3.1.32: ...

... amino-acid n-acetyltransferase MeSH D08.811.913.050.134.150 - carnitine O-acetyltransferase MeSH D08.811.913.050.134.170 - ... carnitine O-acetyltransferase MeSH D08.811.913.050.350.200 - carnitine o-palmitoyltransferase MeSH D08.811.913.050.368 - ... arylamine N-acetyltransferase MeSH D08.811.913.050.331 - atp citrate (pro-s)-lyase MeSH D08.811.913.050.350 - carnitine ... phosphate acetyltransferase MeSH D08.811.913.050.134.850 - serine O-acetyltransferase MeSH D08.811.913.050.170 - acyl-carrier ...

... may refer to: Instrument landing system#ILS categories Chloramphenicol O-acetyltransferase I, an enzyme Carnitine O- ...

... may refer to: Instrument landing system#ILS categories Chloramphenicol O-acetyltransferase II, an enzyme Carnitine O- ...

In pre-synaptic neurons the majority of choline will be acetylated by the enzyme choline acetyltransferase to form the ... and/or carnitine/organic cation transporters (OCTNs), and do not require ATP. Lastly, choline may enter the cell through ...

... acetyltransferase activity PHF7 encoding protein PHD finger protein 7 PRICKLE2: encoding protein Prickle planar cell polarity ... carnitine/acylcarnitine translocase), member 20 STT3B: catalytic subunit of the oligosaccharyltransferase complex SYNPR: ... epicanthus inversus and ptosis type 1 Breast/colon/lung/pancreatic cancer Brugada syndrome Castillo fever Carnitine- ...

Carnitine palmitoyltransferase II deficiency (also known as CPT-II deficiency) leads to an excess long chain fatty acids, as ... Choline acetyltransferase (also known as ChAT or CAT) is an important enzyme which produces the neurotransmitter acetylcholine ... Strauss WL, Kemper RR, Jayakar P, Kong CF, Hersh LB, Hilt DC, Rabin M (Feb 1991). "Human choline acetyltransferase gene maps to ... "Choline O-Acetyltransferase". GeneCards: The Human Gene Compendium. Weizmann Institute of Science. Retrieved 5 December 2013. ...

"Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress ... For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of chromatin architecture, ... There is some evidence that acetyl-L-carnitine may be more effective for some applications than L-carnitine. Acetylation of ...

ACAT1: acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) ACRV1: encoding protein Acrosomal protein SP-10 ... carnitine palmitoyltransferase 1A (liver) CREBZF encoding protein CREB/ATF bZIP transcription factor DAK: Triokinase/FMN ... Beckwith-Wiedemann syndrome Best's disease beta-ketothiolase deficiency beta thalassemia bladder cancer breast cancer carnitine ...

... acetyltransferase inhibitors have also been developed. In 1849, Adolph Strecker was the first to isolate choline from ... Thus, excessive choline intake has been hypothetized to increase these risks in addition to carnitine, which also is formed ...

... carnitine dehydratase - carrier - carveol dehydrogenase - CAT assay - CAT RNA-binding domain - catalase-related immune- ... ribosomal-protein-alanine N-acetyltransferase - ribosomal binding sequence - ribosome - ribosyldihydronicotinamide ...

Carnitine-CoA ligase EC 6.2.1.49: Long-chain fatty acid adenylyltransferase FadD28 EC 6.2.1.50: 4-hydroxybenzoate ... EC 2.3.1 Aminolevulinic acid synthase EC 2.3.1.37 Choline acetyltransferase EC 2.3.1.6 Category:EC 2.3.2 Factor XIII EC 2.3. ...

L-carnitine CoA-transferase and EC 4.2.1.149, crotonobetainyl-CoA hydratase EC 4.2.1.90: L-rhamnonate dehydratase EC 4.2.1.91: ... sulfoacetaldehyde acetyltransferase EC 4.4.1.13: cysteine-S-conjugate β-lyase EC 4.4.1.14: 1-aminocyclopropane-1-carboxylate ... carnitine decarboxylase EC 4.1.1.43: phenylpyruvate decarboxylase EC 4.1.1.44: 4-carboxymuconolactone decarboxylase EC 4.1.1.45 ...

... block for new fatty acids and can inhibit the transfer of the fatty acyl group from acyl CoA to carnitine with carnitine ... functional genomics reveals a role for the lysine acetyltransferase NuA4 and sphingolipid metabolism in regulating Acc1 ...

... formate-C-acetyltransferase]-activating enzyme EC 1.97.1.5: Now EC 1.20.4.1, arsenate reductase (glutaredoxin EC 1.97.1.6: Now ... carnitine 3-dehydrogenase EC 1.1.1.109: Now EC 1.3.1.28, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase EC 1.1.1.110: aromatic ... carnitine 3-dehydrogenase EC 1.1.1.255: mannitol dehydrogenase EC 1.1.1.256: fluoren-9-ol dehydrogenase EC 1.1.1.257: 4-( ... carnitine monooxygenase EC 1.14.13.240: 2-polyprenylphenol 6-hydroxylase EC 1.14.13.241: 5-pyridoxate monooxygenase EC 1.14. ...

Rytting E, Audus KL (January 2005). "Novel organic cation transporter 2-mediated carnitine uptake in placental choriocarcinoma ... the phosphorylation of which induces its association with the histone acetyltransferase, CREB binding protein (CBP) to ... and SLC22A5 is a high-affinity carnitine transporter. Amphetamine is known to strongly induce cocaine- and amphetamine- ...

SLC22A3 is an extraneuronal monoamine transporter that is present in astrocytes, and SLC22A5 is a high-affinity carnitine ... the phosphorylation of which induces its association with the histone acetyltransferase, CREB binding protein (CBP) to ...

Histone acetyltransferases (HATs) are enzymes responsible for the addition of acetyl groups, and histone deacetylases (HDACs) ... placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy". primary. PLOS ONE. 5 (8): e12140. ...