... goblet cells, transit amplifying cells, paneth cells and intestinal stem cells. Over time, the characteristics of the cells ... Hidalgo IJ, Raub TJ, Borchardt RT (March 1989). "Characterization of the human colon carcinoma cell line (Caco-2) as a model ... Pinto M (1983). "Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture". ... Transwell diagram Cell culture Drug development Pre-clinical development PAMPA - a non cell-based permeability assay Lea, Tor ( ...
... difficile cells in colorectal cells, and thus prevent Antibiotic Associated Diarrhea. Due to more than a century of safe use, ... bulgaricus strains to Caco-2 Cells" There are also numerous studies that outline the antimicrobial activity of L. bulgaricus ... Adherence to mucus and human epithelial cells and cell lines and the ability to reduce pathogen adhesion to surfaces is ... Resistance to gastric acidity Bile acid resistance Adherence to mucus and/or human epithelial cells and cell lines ...
NF-Y complex serves as a pioneer factor by promoting chromatin accessibility to facilitate other co-localizing cell type- ... "Transcription factor NF-Y regulates differentiation of CaCo-2 cells". Archives of Biochemistry and Biophysics. 407 (1): 39-44. ... Molecular Cell. 55 (5): 708-22. doi:10.1016/j.molcel.2014.07.005. PMC 4157648. PMID 25132174. "Entrez Gene: NFYA nuclear ... Molecular Cell. 55 (5): 708-22. doi:10.1016/j.molcel.2014.07.005. PMC 4157648. PMID 25132174.[verification needed] Oldfield AJ ...
These cells cause B-cells that recognize gliadin to proliferate. The B-cells mature into plasma cells producing anti-gliadin ... May 2007). "Intestinal translocation capabilities of wheat allergens using the Caco-2 cell line". J. Agric. Food Chem. 55 (11 ... p38 MAP kinase activation by CD3 negative cells (Lamina proxima mononuclear cells) and CD83 on dendritic cells Maiuri L, Ciacci ... The resulting structure can be presented by APC (with the same gliadin recognizing DQ isoforms) to T-cells, and B-cells can ...
... promoting cell-to-cell spread. After infection, Shigella cells multiply intracellularly and spread to neighboring epithelial ... "Shigella flexneri Enters Human Colonic Caco-2 Epithelial Cells through the Basolateral Pole". Infection and Immunity. 60 (1): ... "N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility". Nature Cell ... Hence, Shigella cells may cause dysentery. In rare cases, young children may have seizures. Symptoms can take as long as a week ...
"Identification of Host Cell Factors Associated with Astrovirus Replication in Caco-2 Cells". J. Virol. 89 (20): 10359-70. doi: ... "Alphaherpesvirus axon-to-cell spread involves limited virion transmission". Proceedings of the National Academy of Sciences. ... DNA viruses replicate within the cell nucleus while RNA viruses replicate within the cytoplasm. Exceptions are known to this ... attach to and enter susceptible cells. Basic structural characteristics, such as genome type, virion shape and replication site ...
"Cell atlas - SAAL1 - The Human Protein Atlas". The Human Protein Atlas. Chu PY, Tung SL, Tsai KW, Shen FP, Chan SH (July 2020 ... Immunofluorescent staining has identified SAAL1 localization in the nucleus of Caco-2 cells. However, western blotting of ... doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923. "BoxShade Server". ExPASy. " ... doi:10.1016/j.cell.2015.06.043. PMC 4617211. PMID 26186194. "TMIGD3 - Transmembrane domain-containing protein TMIGD3 - Homo ...
The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although ... 2002). "pCLCA1 becomes a cAMP-dependent chloride conductance mediator in Caco-2 cells". Biochem. Biophys. Res. Commun. 298 (4 ... 2003). "A calcium-activated chloride channel blocker inhibits goblet cell metaplasia and mucus overproduction". Mucus ... 334 (2): 569-76. doi:10.1016/j.bbrc.2005.06.122. PMID 16023076. CLCA1+protein,+human at the U.S. National Library of Medicine ...
2005). Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA pKaflux method. Pharm. Sci., 24: 333-349 ... 2004). PAMPA - a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones. ... Drug development Drug discovery Lipid bilayer Caco-2 cell-based permeability Ottaviani, Giorgio; Martel, Sophie; Carrupt, ... including Caco-2 cultures, the gastrointestinal tract, blood-brain barrier and skin. The donor and/or acceptor compartments may ...
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"Expression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cells". American Journal of Physiology. ... "Downregulation of carnitine acyltransferases and organic cation transporter OCTN2 in mononuclear cells in healthy elderly and ... 162 (2): e34-5. doi:10.1016/j.ijcard.2012.05.038. PMID 22658351. Koizumi A, Nozaki J, Ohura T, Kayo T, Wada Y, Nezu J, Ohashi R ... 3.0.CO;2-8. PMID 10612840. Wang Y, Kelly MA, Cowan TM, Longo N (2000). "A missense mutation in the OCTN2 gene associated with ...
... which transcytoses bidirectionally in Caco-2 cells". The Journal of Biological Chemistry. 270 (35): 20717-20723. doi:10.1074/ ... 146 (2): 534-548. doi:10.1093/brain/awac278. PMC 10169411. PMID 35979925. Gessler M, Klamt B, Tsaoussidou S, Ellis JA, Luzio JP ...
In vitro studies using influenza virus-infected normal human bronchial epithelial cells conducted at the Illinois Institute of ... January 2021). "Enisamium is an inhibitor of the SARS-CoV-2 RNA polymerase and shows improvement of recovery in COVID-19 ... Enisamium iodide effectively inhibited SARS-CoV-2 virus replication in vitro in Caco-2 cells. Enisamium has antiviral activity ... "Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases". bioRxiv. doi:10.1101/2020.04. ...
However, AuNPs conjugated with PEG copolymers showed negligible toxicity towards human colon cells (Caco-2). AuNP toxicity also ... cell health, cell stress, how many cells are taken into a cell), and the capping ligands in solution. In vivo assessments can ... AuNSs size 1.4 nm were found to be toxic in human skin cancer cells (SK-Mel-28), human cervical cancer cells (HeLa), mouse ... In certain doses, AuNSs that have positively-charged ligands are toxic in monkey kidney cells (Cos-1), human red blood cells, ...
"Chicken Eggshell Matrix Proteins Enhance Calcium Transport in the Human Intestinal Epithelial Cells, Caco-2". Journal of ... 62 (2): 199-204. doi:10.1016/S0309-1740(01)00247-9. Wei, Ziku; Xu, Chunli; Li, Baoxin (2009). "Application of waste eggshell as ... doi:10.1016/0012-1606(84)90033-2. PMID 6203793. US6176376B1, MacNeil, Joseph H., "Method and apparatus for separating a protein ...
Many of the commonly coded proteins are cell-surface associated cell-wall hydrolases that protect the cell against apoptosis. ... Gastrointestinal cells are susceptible to apoptosis and cell growth from both heat-killed and viable IMPC2.1 strains. Lc. ... The cells of Lc. paracasei are typically rod shaped, with a size range of 2.0μm to 4.0μm in width, and 0.8 to 1.0μm in length. ... paracasei cells often have square ends, and may exist either in single form or in chains. Lacticaseibacillus paracasei grows ...
Shaulian E, Karin M (May 2002). "AP-1 as a regulator of cell life and death". Nature Cell Biology. 4 (5): E131-6. doi:10.1038/ ... Chang CJ, Chao JC (April 2002). "Effect of human milk and epidermal growth factor on growth of human intestinal Caco-2 cells". ... For example, inactivated c-Jun-ER cells show a normal morphology, while c-Jun-ER activated cells have been shown to be ... The process of skin metabolism is initiated by signals that trigger undifferentiated proliferative cells to undergo cell ...
As an antioxidant, tyrosol may protect cells against injury due to oxidation in vitro. Although it is not as potent as other ... protects against oxidized-LDL-induced injury in Caco-2 cells". J. Nutr. 129 (7): 1269-1277. doi:10.1093/jn/129.7.1269. PMID ...
Szymocha R, Akaoka H, Dutuit M, Malcus C, Didier-Bazes M, Belin MF, Giraudon P (July 2000). "Human T-cell lymphotropic virus ... "EAAT1 is involved in transport of L-glutamate during differentiation of the Caco-2 cell line". American Journal of Physiology. ... In the retina, EAAT1 is expressed in Muller cells. EAAT1 is also expressed in a number of other tissues including cardiac ... The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA ...
... alkaline sphingomyelinase in colon cancer HT-29 cells and a differentiation-related expression of the wild-type enzyme in Caco- ... can inhibit cell proliferation and stimulate cell differentiation and apoptosis. Animal studies showed that supplement of SM or ... alkaline sphingomyelinase in colon cancer HT-29 cells and a differentiation-related expression of the wild-type enzyme in Caco- ... Andersson D, Kotarsky K, Wu J, Agace W, Duan RD (July 2009). "Expression of alkaline sphingomyelinase in yeast cells and anti- ...
Cell Biol. 119 (1): 37-43. doi:10.1007/s00418-002-0479-y. PMID 12548404. S2CID 7822041. Neumann J, Brandsch M (2003). "Delta- ... Sun BW, Zhao XC, Wang GJ, Li N, Li JS (2003). "Hormonal regulation of dipeptide transporter (PepT1) in Caco-2 cells with normal ... "An oligopeptide transporter is expressed at high levels in the pancreatic carcinoma cell lines AsPc-1 and Capan-2". Cancer Res ... "Thyroid hormone regulates the activity and expression of the peptide transporter PEPT1 in Caco-2 cells". Am. J. Physiol. ...
"Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells". Eur J Pharm Sci ... "Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells". Eur J Pharm Sci ... 371 (1-2): 148-55. doi:10.1016/j.ijpharm.2008.12.009. PMID 19124065. Chen Y; Li G; Wu X; Chen Z; Hang J; Qin B; Chen S; Wang R ... 365 (1-2): 136-42. doi:10.1016/j.ijpharm.2008.08.009. PMID 18782611. Cui J; Yu B; Zhao Y; Zhu W; Li H; Lou H; Zhai G (December ...
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. ... Frank PG, Lisanti MP (January 2007). "Caveolin-1 and liver regeneration: role in proliferation and lipogenesis". Cell Cycle. 6 ... "Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric ... Journal of Cell Science. 115 (Pt 23): 4457-67. doi:10.1242/jcs.00130. PMID 12414992. Scherer PE, Lewis RY, Volonte D, Engelman ...
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... and effects on Caco-2 cells by in vitro and in silico studies". Open Chemistry. 20 (1): 299-312. doi:10.1515/chem-2022-0137. ... ET-1 and ICAM-1 production in rat intestinal microvascular endothelial cells". Journal of Ethnopharmacology. 104 (3): 362-366. ... 2 April 2009. p. 4. Retrieved 27 November 2010.[permanent dead link] Duan H, Zhang Y, Xu J, Qiao J, Suo Z, Hu G, Mu X (April ... 53 (2): 271-279. doi:10.1007/s12031-013-0217-z. PMID 24443273. S2CID 255492187. Hou H, Peng Q, Wang S, Zhang Y, Cao J, Deng Y, ...
... cationic block copolymers for the delivery of nucleic acids into a cell (known today as "polyplexes") and developed core-shell ... "Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells". Pharmaceutical Research ... foreign nucleic acid transfer from macrophages to muscle cells and gene expression in the muscle tissue. His papers and ... hypersensitization of multidrug resistant cancer cells, increased drug permeability across brain microvessel endothelial and ...
J. Physiol., Cell Physiol. 292 (1): C332-41. doi:10.1152/ajpcell.00634.2005. PMID 16956961. v t e (Articles with short ... "Regulation of the human taurine transporter by TNF-alpha and an anti-inflammatory function of taurine in human intestinal Caco- ... 1992). "Molecular cloning of the cDNA for an MDCK cell Na(+)- and Cl(−)-dependent taurine transporter that is regulated by ... Han X, Patters AB, Chesney RW (2002). "Transcriptional repression of taurine transporter gene (TauT) by p53 in renal cells". J ...
... inhibits the growth of CaCo-2 colon cancer cell line In Vitro". Phytotherapy Research. 21 (8): 757-761. doi:10.1002/ptr.2159. ... "Anti-Cancer Activity of Gedunin by Induction of Apoptosis in Human Gastric Cancer AGS Cells". Applied Biochemistry and ... 15 (2): 201-209. doi:10.1016/0378-8741(86)90156-X. PMID 3520157. Mitsui, Kumiko; Saito, Hiroaki; Yamamura, Ryota; Fukaya, ...
"Human myeloid dendritic cells treated with supernatants of rotavirus infected Caco-2 cells induce a poor Th1 response". ... Most immune cells (or leukocytes) secrete TGF-β1. Some T cells (e.g. regulatory T cells) release TGF-β1 to inhibit the actions ... It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell ... However, as with other cell types, TGF-β1 can also have the opposite effect on cells of myeloid origin. For example, TGF-β1 ...
"Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu-tang across human intestinal Caco-2 cell ...