CCN intercellular signaling protein: CCN intercellular signaling protein refers to the CCN family of extracellular matrix (ECM)-associated signaling proteins (also known as matricellular proteins).CTGF: CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers.Heparin-binding EGF-like growth factor: Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene.RASopathy: The RASopathies are developmental syndromes caused by germline mutations in genes that alter the Ras subfamily and Mitogen-activated protein kinases that control signal transduction, including:VolociximabCell adhesionWandering cell: In anatomy and histology, the term wandering cell (or ameboid cell)ameboid+cell at eMedicine Dictionary is used to describe cells that are found in connective tissue, but are not fixed in place. This term is used occasionally and usually refers to blood leukocytes (which are not fixed and organized in solid tissue) in particular mononuclear phagocytes.Dermal fibroblast: Dermal fibroblasts are cells within the dermis layer of skin which are responsible for generating connective tissue and allowing the skin to recover from injury. Using organelles (particularly the rough endoplasmic reticulum), dermal fibroblasts generate and maintain the connective tissue which unites separate cell layers.Insulin-like growth factor-binding proteinHaptotaxis: Haptotaxis (from Greek ἅπτω (hapto, "touch, fasten") and τάξις (taxis, "arrangement, order")) is the directional motility or outgrowth of cells, e.g.Perichondritis: Perichondritis is inflammation of the perichondrium, a layer of connective tissue which surrounds cartilage. A common form, auricular perichondritis (perichondritis auriculae) involves infection of the pinna due to infection of traumatic or surgical wound or the spread of inflammation into depth.Rhabdomys: Rhabdomys is a largely Southern African genus of muroid rodents slightly larger than house mice. They are known variously as Striped or Four-Striped mice or rats.Vasculogenesis: Vasculogenesis is the process of blood vessel formation occurring by a de novo production of endothelial cells.Chondrocyte