D-aspartic acid is one of two D-amino acids commonly found in mammals. Apart from a few rare exceptions, D-aspartic acid is not ... Aspartic acid, like glutamic acid, is classified as an acidic amino acid, with a pKa of 3.9; however, in a peptide this is ... The name "aspartic acid" can refer to either enantiomer or a mixture of two. Of these two forms, only one, "L-aspartic acid", ... In addition, aspartic acid acts as a hydrogen acceptor in a chain of ATP synthase. Dietary L-aspartic acid has been shown to ...
... (or ureidosuccinic acid) is a carbamate derivative, serving as an intermediate in pyrimidine ... "ureidosuccinic acid - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 26 March 2005. ... Dicarboxylic acids, All stub articles, Organic compound stubs). ...
a CID 424 from PubChem - racemic ^a CID 83887 from PubChem - (D-aspartic acid) ^a CID 5960 from PubChem - (L-aspartic acid) ^a ...
... or N-methyl-D-aspartate (NMDA) is an amino acid derivative that acts as a specific agonist at the NMDA ... Amino acid derivatives, Aspartic acids, Glutamate (neurotransmitter), Secondary amino acids). ... an isomer of the previously known N-Methyl-DL-aspartic-acid (PubChem ID 4376). NMDA is a water-soluble D-alpha-amino acid - an ... "A specific enzymatic high-performance liquid chromatography method to determine N-methyl-D-aspartic acid in biological tissues ...
... that asparagine and aspartic acid itself are decomposed with a remarkable ease under the influence of nitrous acid, rendering ... Robiquet) and aspartic acid]. Annalen der Chemie (in German). 6: 75-88. doi:10.1002/jlac.18330060111. The empirical formula of ... Proteinogenic amino acids, Glucogenic amino acids, Carboxamides, Alpha-Amino acids). ... "Asparagine and aspartic acid". Journal of the Chemical Society. 31: 457-459. See especially p. 458. Piutti A (1888). "Sintesi e ...
Aspartic acid (aspartate) is one of the most common amino acids in the typical diet. As with methanol and phenylalanine, intake ... Aspartame is a methyl ester of the dipeptide of the natural amino acids L-aspartic acid and L-phenylalanine. Under strongly ... by treatment of aspartic acid with a mixture of formic acid and acetic anhydride. Phenylalanine is converted to its methyl ... aspartic acid, and further metabolites, such as formaldehyde and formic acid. Due to its rapid and complete metabolism, ...
LaPointe CF, Taylor RK (January 2000). "The type 4 prepilin peptidases comprise a novel family of aspartic acid proteases". The ... Bardy SL, Jarrell KF (November 2003). "Cleavage of preflagellins by an aspartic acid signal peptidase is essential for ... Aspartic proteases (also "aspartyl proteases", "aspartic endopeptidases") are a catalytic type of protease enzymes that use an ... Aspartic endopeptidases EC 3.4.23. of vertebrate, fungal and retroviral origin have been characterised. More recently, aspartic ...
The amino acids are identified as V=valine; M=methionine; G=glycine; S=serine, D=aspartic acid; Y=tyrosine, R=arginine; W= ... GATA1-S lacks the first 83 amino acids of GATA1 and therefore consists of only 331 amino acids. GATA1 codes for two zinc finger ... In both GATA1 and GATA1-S, C-ZnF (i.e. C-terminus zinc finger) binds to DNA-specific nucleic acid sequences sites viz., (T/A( ... It is 7.74 kilobases in length, consists of 6 exons, and codes for a full-length protein, GATA1, of 414 amino acids as well as ...
Other amino acids that contribute highly include: alanine (Ala) 8-11%; arginine (Arg) 8-9%; aspartic acid (Asp) 6-7%; and ... The amino acid content of hydrolyzed collagen is the same as collagen. Hydrolyzed collagen contains 19 amino acids, ... Collagen hydrolysis is performed by one of three different methods: acid-, alkali-, and enzymatic hydrolysis. Acid treatment is ... If the raw material used in the production of the gelatin is derived from bones, dilute acid solutions are used to remove ...
2-Aminothiazoline-4-carboxylic acid is an intermediate in one industrial synthesis of L-cysteine for example. Aspartic acid is ... Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although over 500 amino acids ... As both the amine and carboxylic acid groups of amino acids can react to form amide bonds, one amino acid molecule can react ... The other product of transamidation is a keto acid that enters the citric acid cycle. Glucogenic amino acids can also be ...
Knizley H (October 1967). "The enzymatic synthesis of N-acetyl-L-aspartic acid by a water-insoluble preparation of a cat brain ... Goldstein FB (1959). "Biosynthesis of N-acetyl-L-aspartic acid". J. Biol. Chem. 234: 2702-2706. ...
... is a derivative of aspartic acid. Levels are elevated in aspartylglucosaminuria. PubChem. "N- ... Alpha-Amino acids, Amino acid derivatives, Hexosamines, Acetamides, All stub articles, Organic compound stubs). ...
... of a serine amino acid, with the help of two other amino acids (histidine and aspartic acid), on the carbonyl group of the ... The fatty acid, stearic acid, was detected to be the prevailing fatty acid attached to HEF, whereas the fatty acid palmitic ... aspartic acid 352 and histidine 355 are the important amino acids for the esterase activity. Also, early studies showed that ... Along with that, aspartic acid polarizes histidine. X-ray crystallography of the crystalline structure of HEF showed that ...
... and one aspartic acid. For the iron ion to bind, an anion is required, preferably carbonate (CO2− 3). Transferrin also has a ... The amino acids which bind the iron ion to the transferrin are identical for both lobes; two tyrosines, one histidine, ... In humans, each monomer consists of 760 amino acids. It enables ligand bonding to the transferrin, as each monomer can bind to ... Hsu SL, Lin YF, Chou CK (April 1992). "Transcriptional regulation of transferrin and albumin genes by retinoic acid in human ...
Ohmura E, Hayaishi O (1957). "Enzymatic conversion of formylaspartic acid to aspartic acid". J. Biol. Chem. 227: 181-190. ...
"TRDMT1 tRNA aspartic acid methyltransferase 1 (Homo sapiens)". Entrez Gene. NCBI. 2010-11-01. Retrieved 2010-11-07. Yang X, Han ... The name for this methyltransferase has been changed from DNMT2 to TRDMT1 (tRNA aspartic acid methyltransferase 1) to better ... The enzyme is about 1,620 amino acids long. The first 1,100 amino acids constitute the regulatory domain of the enzyme, and the ... the enzyme was shown to methylate position 38 in aspartic acid transfer RNA and does not methylate DNA. ...
Primary amino acids include aspartic acid and proline. It also is a good source of calcium, potassium, and manganese. In growth ...
"Entrez Gene: TRDMT1 tRNA aspartic acid methyltransferase 1". Goll MG, Kirpekar F, Maggert KA, et al. (2006). "Methylation of ... been shown that human DNMT2 does not methylate DNA but instead methylates cytosine 38 in the anticodon loop of aspartic acid ... Nucleic Acids Res. 26 (11): 2536-40. doi:10.1093/nar/26.11.2536. PMC 147598. PMID 9592134. Van den Wyngaert I, Sprengel J, Kass ... Nucleic Acids Res. 29 (2): 439-48. doi:10.1093/nar/29.2.439. PMC 29660. PMID 11139614. Franchina M, Hooper J, Kay PH (2001). " ...
The aspartic acids are the acid/base catalysts. Lastly, once the ligand is attached to the active site, a series of methionines ... The two aspartic acids mentioned above act as proton donors and acceptors. Asp37 and Asp175 are both hydrogen bonded to the ... Mutagenesis studies have also indicated that two aspartic acids are located within the active site and help mediate catalysis ... Phosphopentose utilizes an acid/base type of catalytic mechanism. The reaction proceeds in such a way that trans-2,3-enediol ...
... aminocyclopropanecarboxylic acid; D-cycloserine; L-aspartate; quinolinate, etc. Partial agonists : N-methyl-D-aspartic acid ( ... Ligands include: Agonists: Glutamate, AMPA, 5-Fluorowillardiine, Domoic acid, Quisqualic acid, etc. Antagonists: CNQX, ... Honoré T, Lauridsen J, Krogsgaard-Larsen P (January 1982). "The binding of [3H]AMPA, a structural analogue of glutamic acid, to ... The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (also known as AMPA receptor, or quisqualate receptor) is a ...
... is an aspartic acid-containing dipeptide sweetener. It was developed by Pfizer in the early 1980s and currently ...
If there is an acidic amino acid like aspartic acid or glutamic acid in direct neighborhood to the cutting site, the rate of ... These proteases cut specifically at only one amino acid e.g. Asp-N cuts n-terminal of aspartic acid. Therefore a lower number ... Due to the rareness of the amino acid cysteine for most of the proteins the step of r&a does not effect any improvement of the ... the intended mass spectrometric method with a low concentrated acidic solution of formic acid for ESI and trifluoroacetic acid ...
Adelnia, Hossein; Tran, Huong D.N.; Little, Peter J.; Blakey, Idriss; Ta, Hang T. (2021-06-14). "Poly(aspartic acid) in ... polyaspartic acid, S,S-ethylenediamine-N,N′-disuccinic acid (EDDS), methylglycinediacetic acid (MGDA), and L-Glutamic acid N,N- ... Ethylenediaminetetraacetic acid (EDTA), also called edetic acid after its own abbreviation, is an aminopolycarboxylic acid with ... Adelnia, Hossein; Blakey, Idriss; Little, Peter J.; Ta, Hang T. (2019). "Hydrogels Based on Poly(aspartic acid): Synthesis and ...
... (PASA) is a biodegradable, water-soluble condensation polymer based on the amino acid aspartic acid. It is a ... Saudek, V.; Pivcova, H.; Drobnik, J. (1981). "NMR Study of Poly(aspartic acid). II. α-and β-Peptide Bonds in Poly(aspartic acid ... aspartic acid). I. α-and β-Peptide Bonds in Poly(aspartic acid) Prepared by Thermal Polycondensation". Biopolymers. 20 (8): ... by bulk polycondensation of L-aspartic acid with an acid catalyst". Journal of Polymer Science Part A: Polymer Chemistry. 38 (1 ...
Working with gliadin, he identified α-aminoglutaric acid or glutamic acid in 1866. Then he identified aspartic acid in an ... the discovery of glutamic and aspartic acids as products of the hydrolysis of proteins; second, the realization that hydrolysis ... Karl Heinrich Ritthausen (13 January 1826 - 16 October 1912) was a German biochemist who identified two amino acids and made ... the statement that if proteins differ in amino acid composition, they should also differ in nutritive value to the animal. A ...
... and D-aspartic acid-activating enzyme. Staudenbauer W, Strominger JL (1972). "Activation of D-aspartic acid for incorporation ... Staudenbauer W, Willoughby E, Strominger JL (1972). "Further studies of the D-aspartic acid-activating enzyme of Streptococcus ... the D-aspartate ligase responsible for the addition of D-aspartic acid onto the peptidoglycan precursor of Enterococcus faecium ... This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ...
... versatile disulfide-reducing agent from aspartic acid". Journal of the American Chemical Society. 134 (9): 4057-9. doi:10.1021/ ... The presence of EDTA (ethylenediaminetetraacetic acid) to chelate divalent metal ions (Fe2+, Cu2+ and others) considerably ...
"Homoserine as an Aspartic Acid Precursor for Synthesis of Proteoglycan Glycopeptide Containing Aspartic Acid and a Sulfated ... or citric acid cycle (Krebs cycle), and the aspartate metabolic pathway. It forms by two reductions of aspartic acid via the ... A Synthesis of l -Homoserine from l -Aspartic Acid". Agricultural and Biological Chemistry. 25 (9): 678-679. doi:10.1080/ ... L-Homoserine is not one of the common amino acids encoded by DNA. It differs from the proteinogenic amino acid serine by ...
Versatile Disulfide-Reducing Agent from Aspartic Acid". Journal of the American Chemical Society. American Chemical Society ( ...
Aspartic acid is produced by the addition of ammonia to fumarate using a lyase. Annigan, Jan. "How Many Amino Acids Does the ... The aspartate pathway uses L-aspartic acid as the precursor for the biosynthesis of one fourth of the building block amino ... As a sidenote, AK-III catalyzes the phosphorylation of aspartic acid that is the committed step in this biosynthetic pathway. ... In plants and microorganisms, threonine is synthesized from aspartic acid via α-aspartyl-semialdehyde and homoserine. ...