Arylamine N-acetyltransferase
4-aminobiphenyl N-acetyltransferase, acetyl CoA-arylamine N-acetyltransferase, 2-naphthylamine N-acetyltransferase, arylamine ... arylamine N-acetyltransferase. Other names in common use include arylamine acetylase, beta-naphthylamine N-acetyltransferase, ... N-acetyltransferase, p-aminosalicylate N-acetyltransferase, serotonin acetyltransferase, and serotonin N-acetyltransferase. As ... an arylamine N-acetyltransferase (EC 2.3.1.5) is an enzyme that catalyzes the chemical reaction acetyl-CoA + an arylamine ⇌ {\ ...
N-acetyltransferase
... (NAT) is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines, ... Sinclair, J.C.; Sandy, J.; Delgoda, R.; Sim, E.; Noble, M.E. (2000). "Structure of arylamine N-acetyltransferase reveals a ... May 2008). "Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms". Toxicology. 254 (3): 170- ... June 2008). "Identification of the Xenobiotic-Metabolizing Enzyme Arylamine N-Acetyltransferase 1 as a New Target of Cisplatin ...
N-acetyltransferase 1
... (arylamine N-acetyltransferase) is a protein that in humans is encoded by the NAT1 gene. This gene is one ... "Entrez Gene: N-acetyltransferase 1 (arylamine N-acetyltransferase)". Retrieved 2012-01-27. Gubin AN, Njoroge JM, Bouffard GG, ... "Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos". Human Molecular ... of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat NAT2 genes. The ...
Akane Kawamura
"Structural investigations of arylamine N-acetyltransferases from eukaryotes , WorldCat.org". www.worldcat.org. Retrieved 2023- ...
N-acetyltransferase 2
... (arylamine N-acetyltransferase), also known as NAT2, is an enzyme which in humans is encoded by the NAT2 ... "Entrez Gene: NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)". "NAT2PRED: a computational predictor of the human N- ... A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2. The NAT2 acetylator phenotype can be inferred from ... The Arylamine N-acetyltransferase Gene Nomenclature Committee homepage PDBe-KB provides an overview of all the structure ...
Aralkylamine N-acetyltransferase
Voisin P, Namboodiri MA, Klein DC (1984). "Arylamine N-acetyltransferase and arylalkylamine N-acetyltransferase in the ... The N-acetyltransferase reaction has been suggested to be the rate-determining step, and thus Serotonin N-acetyltransferase has ... Aralkylamine N-acetyltransferase (AANAT) (EC 2.3.1.87), also known as arylalkylamine N-acetyltransferase or serotonin N- ... Aralkylamine N-acetyltransferase belongs to the GCN5-related N-acetyltransferase (GNAT) superfamily which consists 10,000 ...
Multiregional origin of modern humans
March 2006). "Deciphering the Ancient and Complex Evolutionary History of Human Arylamine N-Acetyltransferase Genes". American ...
Virtual screening
... the identification of novel inhibitors of arylamine N-acetyltransferases". Journal of the Royal Society, Interface. 7 (43): 335 ...
N-hydroxyarylamine O-acetyltransferase
Other names in common use include arylhydroxamate N,O-acetyltransferase, arylamine N-acetyltransferase, and N-hydroxy-2- ... O-acetyltransferase and arylamine N-acetyltransferase". J. Biochem. Tokyo. 99 (6): 1689-97. doi:10.1093/oxfordjournals.jbchem. ... In enzymology, a N-hydroxyarylamine O-acetyltransferase (EC 2.3.1.118) is an enzyme that catalyzes the chemical reaction acetyl ... Saito K, Shinohara A, Kamataki T, Kato R (June 1986). "N-hydroxyarylamine O-acetyltransferase in hamster liver: identity with ...
Edith Sim
She identified the structure of arylamine N-acetyltransferase and defined the mechanism of action using a catalytic triad. In ... 2012 John Vane Medal 2015 Lifetime achievement award from the Arylamine N-acetyltransferases Workshop Group Seymour Garte; ... Pharmacological Society John Vane Medal and a lifetime achievement award in 2015 from the Arylamine N-acetyltransferases ... February 1995). "Nomenclature for N-acetyltransferases". Pharmacogenetics and Genomics. 5 (1): 1-17. doi:10.1097/00008571- ...
4-Aminoacetanilide
"Bacillus cereus strain 10-L-2 produces two arylamine N-acetyltransferases that transform 4-phenylenediamine into 4- ...
Serotonin acetyltransferase
... may refer to: Arylamine N-acetyltransferase Serotonin N-acetyltransferase This disambiguation page ... lists articles associated with the title Serotonin acetyltransferase. If an internal link led you here, you may wish to change ...
AADAC
Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes ... Molecular cloning of a novel esterase involved in the metabolic activation of arylamine carcinogens with high sequence ... one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. GRCh38: Ensembl release 89: ...
Acecainide
N-Acetyltransferase is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines and aromatic amines ... These studies claim that ABT is a more potent inhibitor of N-acetyltransferase 2 compared with N-acetyltransferase 1. Strong JM ... Procainamide is metabolized in the liver to acecainide by N-acetyltransferase, an enzyme that is genetically determined. ... Evans DA (1989). "N-acetyltransferase". Pharmacology & Therapeutics. 42 (2): 157-234. doi:10.1016/0163-7258(89)90036-3. PMID ...
List of EC numbers (EC 2)
... arylamine N-acetyltransferase EC 2.3.1.6: choline O-acetyltransferase EC 2.3.1.7: carnitine O-acetyltransferase EC 2.3.1.8: ... D-tryptophan N-acetyltransferase EC 2.3.1.35: glutamate N-acetyltransferase EC 2.3.1.36: D-amino-acid N-acetyltransferase EC ... amino-acid N-acetyltransferase EC 2.3.1.2: imidazole N-acetyltransferase EC 2.3.1.3: glucosamine N-acetyltransferase EC 2.3.1.4 ... glycine C-acetyltransferase EC 2.3.1.30: serine O-acetyltransferase EC 2.3.1.31: homoserine O-acetyltransferase EC 2.3.1.32: ...
Cetoniacytone A
... cetoniacytone B is acetylated via an arylamine N-acetyltransferase (CetD) to yield cetoniacytone A. Mahmud, Taifo (2003). "The ...
Fucoxanthin
... and arylamine-N-acetyltransferase (TBNAT). Limited studies of the bioavailability of fucoxanthin in humans suggest that it is ...
List of MeSH codes (D08)
... arylalkylamine n-acetyltransferase MeSH D08.811.913.050.313 - arylamine N-acetyltransferase MeSH D08.811.913.050.331 - atp ... acetyl-CoA C-acetyltransferase MeSH D08.811.913.050.134.105 - amino-acid n-acetyltransferase MeSH D08.811.913.050.134.150 - ... phosphate acetyltransferase MeSH D08.811.913.050.134.850 - serine O-acetyltransferase MeSH D08.811.913.050.170 - acyl-carrier ... acetyltransferases MeSH D08.811.913.050.134.029 - acyl-carrier protein s-acetyltransferase MeSH D08.811.913.050.134.060 - ...
4-Aminobiphenyl
The N-hydroxy aryl amine N-glucuronide conjugate is thought to be excreted from the liver and to build up in the bladder lumen ... O-Acetylation reactions are catalyzed by NAT, N-acetyltransferase; and UDP-glucuronosyltransferase (UGT) enzymes. Two different ... Exposure to this aryl-amine can happen through contact with chemical dyes and from inhalation of cigarette smoke. Researches ... of 4-aminobiphenyl and N-hydroxy-4-aminobiphenyl can be hydrolyzed by acidic urine to their corresponding arylamines, they can ...
2-Aminofluorene
... (2-AF) is a synthetic arylamine. It is a white to tan solid with a melting point of 125-132 °C. 2-AF has only ... The transferase enzyme, cytosolic N-acetyltransferase can act on the hydroxyl group which can also be acetylated. This oxygen ...
O-Toluidine
Eyer, P. (1983). "The Red Cell as a Sensitive Target for Activated Toxic Arylamines". Toxicology in the Use, Misuse, and Abuse ... react directly with DNA or be bio-activated via sulfation or acetylation by cytosolic sulfotransferases or N-acetyltransferases ...