Arginine-tRNA ligase
In enzymology, an arginine-tRNA ligase (EC 6.1.1.19) is an enzyme that catalyzes the chemical reaction ATP + L-arginine + ... arginine-tRNA synthetase, and arginine translase. This enzyme participates in arginine and proline metabolism and aminoacyl- ... L-arginine, and tRNA(Arg), whereas its 3 products are AMP, diphosphate, and L-arginyl-tRNA(Arg). This enzyme belongs to the ... The systematic name of this enzyme class is L-arginine:tRNAArg ligase (AMP-forming). Other names in common use include arginyl- ...
RARS (gene)
Overview of all the structural information available in the PDB for UniProt: P54136 (Human Arginine--tRNA ligase, cytoplasmic) ... McCune SA, Yu PL, Nance WE (1977). "A genetic study of erythrocyte arginine-tRNA synthetase activity in man". Acta Geneticae ... Arginyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the RARS gene. Aminoacyl-tRNA synthetases ... Arginyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Mutations in RARS cause hypomyelination. RARS ...
Canavanine
The beetle Caryedes brasiliensis is able to tolerate this however as it has the most highly discriminatory arginine-tRNA ligase ... presumably by virtue of highly discriminatory arginine-tRNA ligase, the enzyme responsible for the first step in the ... of dietary canavanine because their arginine-tRNA ligase has little, if any, discriminatory capacity. No one has examined ... experimentally the arginine-tRNA synthetase of these organisms. But comparative studies of the incorporation of radiolabeled L- ...
Proline-tRNA ligase
... and tRNA(Pro), whereas its 3 products are AMP, diphosphate, and L-prolyl-tRNA(Pro). This enzyme participates in arginine and ... This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related ... In enzymology, a proline-tRNA ligase (EC 6.1.1.15) is an enzyme that catalyzes the chemical reaction ATP + L-proline + tRNAPro ... and prolinyl-tRNA ligase. Norton SJ (July 1964). "Purification and Properties of the Prolyl RNA Synthetase of Escherichia Coli ...
Morganellaceae
... histidine-tRNA ligase, and N-acetylmuramoyl-L-alanine amidase. These molecular signatures provide a novel and reliable means of ... These bacteria are oxidase-negative, and negative for arginine decarboxylase and Voges-Proskauer test. Seven conserved ...
List of MeSH codes (D08)
... alanine-tRNA ligase MeSH D08.811.464.263.200.100 - arginine-tRNA ligase MeSH D08.811.464.263.200.150 - aspartate-tRNA ligase ... glutamate-trna ligase MeSH D08.811.464.263.200.350 - glycine-trna ligase MeSH D08.811.464.263.200.400 - histidine-trna ligase ... isoleucine-trna ligase MeSH D08.811.464.263.200.500 - leucine-trna ligase MeSH D08.811.464.263.200.550 - lysine-trna ligase ... serine-trna ligase MeSH D08.811.464.263.200.800 - threonine-tRNA ligase MeSH D08.811.464.263.200.850 - tryptophan-tRNA ligase ...
List of EC numbers (EC 6)
... cysteine-tRNA ligase EC 6.1.1.17: glutamate-tRNA ligase EC 6.1.1.18: glutamine-tRNA ligase EC 6.1.1.19: arginine-tRNA ligase EC ... threonine-tRNA ligase EC 6.1.1.4: leucine-tRNA ligase EC 6.1.1.5: isoleucine-tRNA ligase EC 6.1.1.6: lysine-tRNA ligase EC 6.1. ... valine-tRNA ligase EC 6.1.1.10: methionine-tRNA ligase EC 6.1.1.11: serine-tRNA ligase EC 6.1.1.12: aspartate-tRNA ligase EC ... phenylalanine-tRNA ligase EC 6.1.1.21: histidine-tRNA ligase EC 6.1.1.22: asparagine-tRNA ligase EC 6.1.1.23: aspartate-tRNAAsn ...
Metalysinibacillus
... cysteine-tRNA ligase, coproporphyrinogen III oxidase, and PBP1A family penicillin-binding protein. These molecular signatures ... arginine-binding extracellular protein ArtP precursor, oxygen-independent coproporphyrinogen III oxidase, putative hydrolase ... MhqD, helix-turn-helix transcriptional regulator, tRNA preQ1(34)S-adenosylmethionine ribosyltransferase-isomerase QueA, DNA ...
Leucyl-tRNA synthetase
... has been shown to interact with EEF1G. BC-LI-0186 Tavaborole Leucine-tRNA ligase GRCh38: Ensembl release ... It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C ... This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded ... Lue SW, Kelley SO (April 2007). "A single residue in leucyl-tRNA synthetase affecting amino acid specificity and tRNA ...
Chromosome 12
... encoding enzyme tRNA pseudouridine synthase A PUS7L: encoding enzyme Pseudouridylate synthase 7 homolog-like protein PZP: ... encoding protein Protein arginine methyltransferase 8 PRR4: encoding protein Proline-rich protein 4 PTMS: encoding protein ... encoding enzyme E3 ubiquitin-protein ligase RNF34 SARNP: SAP domain-containing ribonucleoprotein Serpina3f: encoding protein ... "genetype trna"[Properties] OR "genetype scrna"[Properties] OR "genetype snrna"[Properties] OR "genetype snorna"[Properties]) ...
List of EC numbers (EC 2)
... glutamate-tRNA ligase, EC 1.2.1.70, glutamyl-tRNA reductase and EC 5.4.3.8 glutamate-1-semialdehyde 2,1-aminomutase EC 2.7.2.14 ... tRNA-guanosine34 preQ1 transglycosylase EC 2.4.2.30: NAD+ ADP-ribosyltransferase EC 2.4.2.31: NAD+-protein-arginine ADP- ... tRNA (guanine46-N7)-methyltransferase EC 2.1.1.34: tRNA (guanosine18-2′-O)-methyltransferase EC 2.1.1.35: tRNA (uracil54-C5)- ... tRNA (guanine110-N2)-dimethyltransferase EC 2.1.1.214: tRNA (guanine10-N2)-methyltransferase EC 2.1.1.215: tRNA (guanine26-N2/ ...
C8orf58
MetG1 (Methionine-tRNA ligase) is required for elongation of protein synthesis and the initiation of all mRNA translation ... It is proline and arginine rich and isoleucine, asparagine, phenylalanine, and tyrosine poor. The predicted secondary structure ... tRNA ligase GeneCard. 8orf58 Gene(Protein Coding) Chromosome 8 Open Reading Frame 58. [5]. v t e (Articles with short ... through initiator tRNA(fMet) aminoacylation. An important paralog of this gene is ENSG00000248235. Orthologs of the human gene ...
Aminoacyl tRNA synthetase
An aminoacyl-tRNA synthetase (aaRS or ARS), also called tRNA-ligase, is an enzyme that attaches the appropriate amino acid onto ... "Backbone Brackets and Arginine Tweezers delineate Class I and Class II aminoacyl tRNA synthetases". PLOS Computational Biology ... If the incorrect tRNA is added (aka. the tRNA is found to be improperly charged), the aminoacyl-tRNA bond is hydrolyzed. This ... tRNA + ATP → Aminoacyl-tRNA + AMP + PPi Some synthetases also mediate an editing reaction to ensure high fidelity of tRNA ...
Chromosome 1
... also known as arginine decarboxylase (ADC) BCAS2: Breast carcinoma amplified sequence 2 BCL10 (1p22) LRIF1: encoding protein ... E3 ubiquitin-protein ligase component n-recognin 4 UROD: uroporphyrinogen decarboxylase (the gene for porphyria cutanea tarda) ... Tryptophanyl-tRNA synthetase, mitochondrial WDR77 (1p13) YBX1 (1p34) ZCCHC17: zinc finger CCHC-type containing 17 ZFP69: ... Protein arginine methyltransferase 6 PRXL2B: encoding protein Peroxiredoxin like 2B PSRC1: Proline/serine-rich coiled-coil ...
N-end rule
In eukaryotic cells, these N-terminal residues are recognized and targeted by ubiquitin ligases, mediating ubiquitination ... such as arginine, lysine, leucine, phenylalanine, tyrosine, and tryptophan, have short half-lives of around 2-minutes and are ... destabilising residues are modified by the attachment of a Primary destabilising residue by the enzyme leucyl/phenylalanyl-tRNA ... but inefficient when it is bulky and charged such as arginine. Once the f-Met is removed, the second residue becomes the N- ...
Arginylation
... addition of an arginine moiety to acidic NH2 termini of proteins is required for their recognition by ubiquitin-protein ligase ... Balzi E, Choder M, Chen WN, Varshavsky A, Goffeau A (May 1990). "Cloning and functional analysis of the arginyl-tRNA-protein ... It has also been observed that a variety of physiological compounds and drugs are able to affect the incorporation of arginine ... Enzymes such as Aminopeptidase B and Carboxypeptidase B are able to remove arginine from a proteins N-terminus and from side ...
Parkin (protein)
... p38 tRNA synthase, Pael-R, synaptotagmin XI, sp22 and parkin itself (see also ubiquitin ligase). Additionally, parkin contains ... crystallisation of parkin revealed a cationic pocket in RING0 formed by lysine and arginine residues Lys161, Arg163 and Lys211 ... "Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases". Nature Communications. 4: 1982 ... Parkin is a 465-amino acid residue E3 ubiquitin ligase, a protein that in humans and mice is encoded by the PARK2 gene. Parkin ...
Chromosome 21
... ligase) HMGN1: encoding non-histone chromosomal protein HMG-14 HSPA13: encoding heat shock 70 kDa protein 13 ICOSLG: encoding ... encoding tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 ZBTB21: encoding zinc finger and BTB domain- ... encoding enzyme protein arginine N-methyltransferase 2 PSMG1: encoding protein proteasome assembly chaperone 1 PTTG1IP: ... "genetype trna"[Properties] OR "genetype scrna"[Properties] OR "genetype snrna"[Properties] OR "genetype snorna"[Properties]) ...
List of biomolecules
... tRNA) Triacsin C Thyroid-stimulating hormone (TSH) Thyrotropin-releasing hormone (TRH) Thyroxine (T4) Tocopherol (Vitamin E) ... Arabinose Arginine Argonaute Ascomycin Ascorbic acid (vitamin C) Asparagine Aspartic acid Asymmetric dimethylarginine ATP ... Lactase Lactic acid Lactose Lanolin Lauric acid Lectin Leptin Leptomycin B Leucine Leukotriene Ligase Lignin Limonene Linalool ... Dextran Dextrin Dicer Dihydrotestosterone DNA DNA polymerase DNA ligase Dopamine Endonuclease Enzyme Ephedrine Epinephrine - ...
Chromosome 19
... arginine/serine-rich 14 SFRS16: encoding protein Splicing factor, arginine/serine-rich 16 SLC5A5: Solute carrier family 5 ( ... Gene map locus 19q13.2 FCGBP: Fc fragment of IgG binding protein SARS2: seryl-tRNA synthetase 2, mitochondrial. Gene map locus ... encoding enzyme Long-chain-fatty-acid-CoA ligase ANKRD24: encoding protein Ankyrin repeat domain-containing protein 24 ARMC6: ... "genetype trna"[Properties] OR "genetype scrna"[Properties] OR "genetype snrna"[Properties] OR "genetype snorna"[Properties]) ...
Housekeeping gene
002884 arginyl-tRNA synthetase RARS2 NM_020320 arginyl-tRNA synthetase 2, mitochondrial SARS NM_006513 Homo sapiens seryl-tRNA ... arginine/serine-rich EIF1 aka SUI1 EIF1AD EIF1B EIF2A EIF2AK1 EIF2AK3 EIF2AK4 EIF2AK1 EIF2B2 EIF2B3 EIF2B4 EIF2S2 EIF3A EIF3B ... 021178 E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression ... 001261434 alanyl-tRNA synthetase domain containing 1 CARS NM_001751 cysteinyl-tRNA synthetase CARS2 NM_024537 cysteinyl-tRNA ...
Karelsulcia muelleri
... the phenylalanine-tRNA ligase beta-subunit, VARS, elongation factor Tu, the RNA polymerase beta-subunit, and the ribosomal ... arginine, phenylalanine, and tryptophan. Some strains of "Ca. K. muelleri" are incapable of making the amino acid, tryptophan. ... K. muelleri" lacks a full set of Aminoacyl tRNA synthetases; surprisingly, however, it possesses all of the genes necessary to ... The proteins used were the DNA polymerase III beta-subunit, initiation factor IF-2, leucyl-tRNA synthetase, ...
List of enzymes
Glutarate-CoA ligase EC 6.2.1.7: Cholate-CoA ligase EC 6.2.1.8: Oxalate-CoA ligase EC 6.2.1.9: Malate-CoA ligase EC 6.2.1.10: ... L-seryl-tRNA(Sec) selenium transferase EC 2.9.1.2: O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase Hydrolytic ... Protein arginine phosphatase EC 3.9.1.3: Phosphohistidine phosphatase EC 3.10.1.1: N-sulfoglucosamine sulfohydrolase EC 3.10. ... ligase EC 6.2.1.23: Dicarboxylate-CoA ligase EC 6.2.1.24: Phytanate-CoA ligase EC 6.2.1.25: Benzoate-CoA ligase EC 6.2.1.26: o- ...
Translocase
This entry comprises bacterial enzymes that import Histidine, Arginine, Lysine, Glutamine, Glutamate, Aspartate, ornithine, ... and ligases (EC 6). However, it became apparent that none of these could describe the important group of enzymes that catalyse ... tRNA) and messenger RNA (mRNA) through the ribosome. The enzyme classification and nomenclature list was first approved by the ...
Biosynthesis
... tRNA ↽ − − ⇀ aminoacyl − tRNA + AMP {\displaystyle {\ce {{Aminoacyl-AMP}+ tRNA <=> {aminoacyl-tRNA}+ AMP}}} The combination of ... Okazaki fragments are covalently joined by DNA ligase to form a continuous strand. Then, to complete DNA replication, RNA ... In the first step of arginine biosynthesis in bacteria, glutamate is acetylated by transferring the acetyl group from acetyl- ... This reaction, called tRNA charging, is catalyzed by aminoacyl tRNA synthetase. A specific tRNA synthetase is responsible for ...
Chromosome 2
Ubiquitin ligase PLGLB2: Plasminogen-related protein B POLR1A: DNA-directed RNA polymerase I subunit RPA1 PREPL: Prolyl ... "genetype trna"[Properties] OR "genetype scrna"[Properties] OR "genetype snrna"[Properties] OR "genetype snorna"[Properties]) ... Protein arginine methyltransferase NDUFAF7, mitochondrial NRBP1: Nuclear receptor-binding protein 1 ODC1: Ornithine ... encoding protein Neuralized E3 ubiquitin protein ligase 3 NCL: Nucleolin NR4A2: nuclear receptor subfamily 4, group A, member 2 ...
Mitochondrion
Mitochondrial tRNA genes have different sequences from the nuclear tRNAs, but lookalikes of mitochondrial tRNAs have been found ... In higher plants, it was thought that CGG encoded for tryptophan and not arginine; however, the codon in the processed RNA was ... kynurenine hydroxylase and fatty acid Co-A ligase. Disruption of the outer membrane permits proteins in the intermembrane space ... It encodes 37 genes: 13 for subunits of respiratory complexes I, III, IV and V, 22 for mitochondrial tRNA (for the 20 standard ...
Stress granule
Narayanan N, Wang Z, Li L, Yang Y (2017). "Arginine methylation of USP9X promotes its interaction with TDRD3 and its anti- ... eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules". Molecular Biology ... "Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity". Proceedings of the National ... Tsai WC, Reineke LC, Jain A, Jung SY, Lloyd RE (November 2017). "Histone arginine demethylase JMJD6 is linked to stress granule ...
Ribosomal RNA
... site contains an aminoacyl-tRNA (a tRNA esterified to an amino acid on the 3' end). The P (peptidyl) site contains a tRNA ... Mms1p and Rtt101p are found to bind together and Rtt101p is believed to recruit a ubiquitin E3 ligase complex, allowing for the ... lysine and arginine). All ribosomal proteins (including the specific sequences that bind to rRNA) have been identified. These ... In the SSU, the mRNA interacts with the anticodons of the tRNA. In the LSU, the amino acid acceptor stem of the tRNA interacts ...
List of EC numbers (EC 4)
... tRNA-intron lyase EC 4.6.1.17: cyclic pyranopterin monophosphate synthase * EC 4.6.1.18: pancreatic ribonuclease * EC 4.6.1.19 ... heme ligase EC 4.99.1.9:: coproporphyrin ferrochelatase * EC 4.99.1.10: magnesium dechelatase * EC 4.99.1.11: sirohydrochlorin ... arginine decarboxylase EC 4.1.1.20: diaminopimelate decarboxylase EC 4.1.1.21: phosphoribosylaminoimidazole carboxylase EC 4.1. ... tRNA 4-demethylwyosine synthase (AdoMet-dependent) * EC 4.1.3.45: 3-hydroxybenzoate synthase * EC 4.1.3.46: (R)-citramalyl-CoA ...