GemOx
... an antimetabolite; (Ox)aliplatin - a platinum-based alkylating antineoplastic agent. GEMOX-R regimen is a highly effective ...
FCM (chemotherapy)
... an antimetabolite; Cyclophosphamide - an alkylating antineoplastic agent from the oxazafosforine group; Mitoxantrone - a ...
Bisantrene
... is an anthracenyl bishydrazone with anthracycline-like antineoplastic activity and an antimetabolite. Bisantrene intercalates ...
Antimetabolite
Antineoplastic+Antimetabolites at the U.S. National Library of Medicine Medical Subject Headings (MeSH) "How Chemotherapy Drugs ... An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal ... Anti-metabolites also affect RNA synthesis. However, because thymidine is used in DNA but not in RNA (where uracil is used ... Antimetabolites can be used in cancer treatment, as they interfere with DNA production and therefore cell division and tumor ...
Thymidylate synthase inhibitor
v t e v t e (Antineoplastic antimetabolites, Thymidylate synthase inhibitors, All stub articles, Biochemistry stubs, Oncology ...
FOLFOXIRI
... a platinum-based antineoplastic agent, which inhibits DNA repair and/or DNA synthesis; IRI - irinotecan (Camptosar), a ... a pyrimidine analog and antimetabolite which incorporates into the DNA molecule and stops DNA synthesis; OX - oxaliplatin ( ...
FOLFIRINOX
... a platinum-based antineoplastic agent, which inhibits DNA repair and/or DNA synthesis. The regimen emerged in 2010 as a new ... a pyrimidine analog and antimetabolite which incorporates into the DNA molecule and stops DNA synthesis; IRIN - irinotecan ( ...
Cancer
Chemotherapy is the treatment of cancer with one or more cytotoxic anti-neoplastic drugs (chemotherapeutic agents) as part of a ... which are divided into broad categories such as alkylating agents and antimetabolites. Traditional chemotherapeutic agents act ...
Chemotherapy
Anti-metabolites are a group of molecules that impede DNA and RNA synthesis. Many of them have a similar structure to the ... Antineoplastic drugs may also increase the risk of learning disabilities among children of health care workers who are exposed ... Unlike alkylating agents, anti-metabolites are cell cycle dependent. This means that they only work during a specific part of ... In the 1970s, antineoplastic (chemotherapy) drugs were identified as hazardous, and the American Society of Health-System ...
List of MeSH codes (D27)
... antimetabolites, antineoplastic MeSH D27.505.954.248.147 - antimitotic agents MeSH D27.505.954.248.150 - antineoplastic agents ... antimetabolites MeSH D27.888.569.042.030 - antimetabolites, antineoplastic MeSH D27.888.569.071 - antispermatogenic agents MeSH ... antimetabolites, antineoplastic MeSH D27.505.519.217 - antioxidants MeSH D27.505.519.217.500 - free radical scavengers MeSH ... antineoplastic agents MeSH D27.505.954.248.025 - angiogenesis inhibitors MeSH D27.505.954.248.106 - antibiotics, antineoplastic ...
Hydroxycarbamide
Antineoplastic antimetabolites, Bristol Myers Squibb, IARC Group 3 carcinogens, Wikipedia medicine articles ready to translate ... 2015). Hydroxyurea is a monohydroxyl-substituted urea (hydroxycarbamate) antimetabolite. Similar to other antimetabolite anti- ... Hydroxycarbamide is in the antineoplastic family of medications. It is believed to work by blocking the making of DNA. ... Hydroxyurea has many pharmacological applications under the Medical Subject Headings classification system: Antineoplastic ...
Cotton wool spots
Cladribine, also known by its brand name Mavenclad, is a purine antimetabolite and antineoplastic drug used to reduce relapse ...
Index of oncology articles
... antimetabolite - antimicrotubule agent - antimitotic agent - antineoplastic - antineoplastic antibiotic - antioxidant - ...
DHAP (chemotherapy)
... an antimetabolite; (P)latinol (cisplatin), a platinum-based antineoplastic, also an alkylating antineoplastic agent. Effective ...
Mercaptopurine
Official information from the package insert for purinethol: Mercaptopurine is an antimetabolite antineoplastic, as such it ... Mercaptopurine is in the thiopurine and antimetabolite family of medications. Mercaptopurine was approved for medical use in ... Specifically, Mercaptopurine is a purine antimetabolite or purine antagonist as such inhibits DNA synthesis by inhibiting the ...
Chronic myelogenous leukemia
In the past, antimetabolites (e.g., cytarabine, hydroxyurea), alkylating agents, interferon alfa 2b, and steroids were used as ... Despite the move to replacing cytotoxic antineoplastics (standard anticancer drugs) with tyrosine kinase inhibitors sometimes ...
FLAG (chemotherapy)
G-CSF is still included, even though the "G" is taken out of the acronym.) Amsacrine is an alkylating antineoplastic agent that ... an antimetabolite that has been proven to be the most active toward AML among various cytotoxic drugs in single-drug trials; ... an antimetabolite that, while not active toward AML, increases formation of an active cytarabine metabolite, ara-CTP, in AML ...
Phototrexate
Matera C, Gomila AM, Camarero N, Libergoli M, Soler C, Gorostiza P (November 2018). "Photoswitchable Antimetabolite for ... Antineoplastic and immunomodulating drug stubs). ...
8-Azaguanine
It shows antineoplastic activity and has been used in the treatment of acute leukemia. The compound closely resembles guanine ... Timmis, G.M.; Williams, Donald Charles (1967). "Chemotherapy of Cancer: the Antimetabolite Approach". Butterworths. University ...
Tioguanine
... is in the antimetabolite family of medications. It is a purine analogue of guanine and works by disrupting DNA and ... The second pathway is the methylation of thioguanine to 2-amino-6-methylthiopurine, which is minimally effective as an anti-neoplastic ... One route is through the deamination by the enzyme guanine deaminase to 6-thioxanthine, which has minimal anti-neoplastic ... Baca QJ, Coen DM, Golan DE (2011). "Principles of antimicrobial and antineoplastic therapy". In Golan DE, Tashjian AH, ...
Thiopurine
The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune ... Antineoplastic and immunomodulating drug stubs). ...
Treatment of lung cancer
Pemetrexed Pemetrexed functions as an antimetabolite. Pemetrexed inhibits thymidylate synthase, dihydrofolate reductase and ... and approved pembrolizumab in combination with pemetrexed and platinum-based antineoplastic (carboplatin or cisplatin) as first ...
Pentostatin
It is classified as a purine analog, which is a type of antimetabolite. It mimics the nucleoside adenosine and thus inhibits ... Antineoplastic and immunomodulating drug stubs). ...
Doxifluridine
5-fluorouracil (5-FU), the nucleobase of doxifluridine, is currently an FDA-approved antimetabolite. 5-FU is normally ... Antineoplastic drugs, Nucleosides, Organofluorides, Fluoropyrimidines). ...
Methotrexate
... is an antimetabolite of the antifolate type. It is thought to affect cancer and rheumatoid arthritis by two ... Antineoplastic and immunomodulating drugs, Benzamides, Chemotherapy, Disease-modifying antirheumatic drugs, Folates, ...