An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal ... Anti-metabolites also affect RNA synthesis. However, because thymidine is used in DNA but not in RNA (where uracil is used ... Antimetabolites can be used in cancer treatment, as they interfere with DNA production and therefore cell division and tumor ... Antimetabolite drugs are commonly used to treat leukemia, cancers of the breast, ovary, and the gastrointestinal tract, as well ...

Carmen AJ, Carlos M (2008). "Chapter 2 - Antimetabolites". Medicinal Chemistry of Anticancer Drugs. pp. 9-52. doi:10.1016/B978- ...

... an antimetabolite; Cyclophosphamide - an alkylating antineoplastic agent from the oxazafosforine group; Mitoxantrone - a ...

... an antimetabolite; (M)itoxantrone - a synthetic anthracycline analogue (an anthraquinone) that is able to intercalate DNA and ...

... an antimetabolite; (T)hioguanine - another antimetabolite. Randomized Comparison of DAT Versus ADE as Induction Chemotherapy in ...

It is an antimetabolite. It is used as one of a few experimental treatments for patients with deadly pancreatic cancer when the ... Antimetabolites, Amino acid derivatives, 2,3-Diaminopropionic acids, Nitrosamines, Experimental drugs, Toxic amino acids, All ...

... an antimetabolite; (Ox)aliplatin - a platinum-based alkylating antineoplastic agent. GEMOX-R regimen is a highly effective ...

... enhancement by antimetabolites". Proceedings of the National Academy of Sciences of the United States of America. 67 (1): 464- ...

Investigation of selected purine derivatives (antimetabolites) membrane transport. Determination of protein effects of the O2 ...

Antimetabolites interfere with the synthesis of nucleic acids. These include: folic acid analogues, such as methotrexate purine ...

Anti-metabolites are a group of molecules that impede DNA and RNA synthesis. Many of them have a similar structure to the ... Unlike alkylating agents, anti-metabolites are cell cycle dependent. This means that they only work during a specific part of ... Subtypes of the anti-metabolites are the anti-folates, fluoropyrimidines, deoxynucleoside analogues and thiopurines. The anti- ... Parker WB (July 2009). "Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer". Chemical Reviews ...

Books by Woolley included A Study of Antimetabolites (1952), and The Biochemical Bases of Psychoses (1962). Woolley married ... Dilworth Wayne Woolley, A Study of Antimetabolites (Wiley 1952). Dilworth Wayne Woolley, The Biochemical Bases of Psychoses, or ...

Immunosuppressive agents include T-cell inhibitors such as cyclosporine and tacrolimus; antimetabolites such as azathioprine, ...

Antimetabolites have been used with intent to increase the success rates of dacryocystorhinostomy. At a follow-up time of more ... The use of antimetabolites had only minor side effects. Atrophic rhinitis is an absolute contraindication. In case of acute ... Cochrane Eyes and Vision Group) (April 2020). "Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct ... than six months, antimetabolites may improve functional and anatomic results. ...

Timmis, G.M.; Williams, Donald Charles (1967). "Chemotherapy of Cancer: the Antimetabolite Approach". Butterworths. University ...

Matera C, Gomila AM, Camarero N, Libergoli M, Soler C, Gorostiza P (November 2018). "Photoswitchable Antimetabolite for ...

Pemetrexed Pemetrexed functions as an antimetabolite. Pemetrexed inhibits thymidylate synthase, dihydrofolate reductase and ...

CS1 maint: uses authors parameter, Vitamin K antagonists, Rodenticides, Antimetabolites). ...

Pyrimidine analogues are antimetabolites that interfere with nucleic acid synthesis. Some of them have been shown to fit the ...

... is an antimetabolite and methionine antagonist. It prevents amino acid incorporation into proteins and interferes ...

... s are antimetabolites which mimic the structure of metabolic pyrimidines. Nucleobase analogues Fluorouracil ... Parker, William B. (2009). "Enzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of Cancer". Chem Rev. 109 ... v t e (Articles needing additional references from July 2013, All articles needing additional references, Antimetabolites, ... Gemcitabine Nucleotide analogues Pyrimidine Fluorouracil Floxuridine Gemcitabine Pyrimidine antimetabolites are commonly used ...

... s are antimetabolites that mimic the structure of metabolic purines. Nucleobase analogues Thiopurines such as ... Parker, William B. (2009). "Enzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of Cancer". Chem Rev. 109 ... v t e (Articles with short description, Short description matches Wikidata, Antimetabolites, Purines, All stub articles, ... Purine Mercaptopurine Thioguanine Fludarabine Purine antimetabolites are commonly used to treat cancer by interfering with DNA ...

The antimetabolites azathioprine and mycophenolic acid have an intermediate risk profile. Diagnosis is confirmed via skin ...

... is in the antimetabolite family of medications. It is a purine analogue of guanine and works by disrupting DNA and ...

Antimetabolite Biopesticide Plant defense against herbivory Cammack, Richard; Atwood, Teresa; Campbell, Peter; Parish, Howard; ...

... , an antimetabolite of vitamin K". Arch. Mikrobiol. 65 (4): 303-17. doi:10.1007/BF00412210. PMID 4988744. S2CID ...

... is an antimetabolite of the antifolate type. It is thought to affect cancer and rheumatoid arthritis by two ...

2015). Hydroxyurea is a monohydroxyl-substituted urea (hydroxycarbamate) antimetabolite. Similar to other antimetabolite anti- ... Antineoplastic antimetabolites, Bristol Myers Squibb, IARC Group 3 carcinogens, Wikipedia medicine articles ready to translate ...

... is assumed to be an antimetabolite of arginine. Many studies have shown that it acts as a competitive inhibitor in ...

Mercaptopurine is a cytostatic drug that is an antimetabolite. The mercaptopurine molecule mimics purine, which is necessary ...