... s or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can ... The resistance to anti-malarials may be increased by a process found in some species of Plasmodium, where a degree of ... Anti-malarial drug resistance has been defined as: "the ability of a parasite to survive and/or multiply despite the ... The prevention of anti-malarial drug resistance is of enormous public health importance. It can be assumed that no therapy ...
Wilson was married when she completed her PhD in biology at Radcliffe College, with a dissertation on antimalarials. Her ... Wilson, Evelyn (Hodes) (1946). Antimalarials. Radcliffe College. "Boston Girl Wins Honor at Radcliffe Commencement". The Boston ...
Another example is in the synthesis of antimalarials as aminoalkylamino derivatives of 2,3-dihydrofuroquinolines The Gould ... Cruickshank, Philip A. (1970). "Antimalarials. 1. Aminoalkylamino derivatives of 2,3-dihydrofuroquinolines". Journal of ...
D.E. Pearson; Adam Rosenberg (1975). "Potential antimalarials. 9. Resolution of alpha-diheptylaminomethyl-6-9-phenanthrenes-an ... accepted a position at Vanderbilt University as an Assistant Professor of Chemistry and began research developing antimalarial ...
Carrington, H. C.; Crowther, A. F.; Stacey, G. J. (1954). "Synthetic antimalarials. Part XLIX. The structure and synthesis of ... Cycloguanil is a dihydrofolate reductase inhibitor, and is a metabolite of the antimalarial drug proguanil; its formation in ... Although cycloguanil is not currently in general use as an antimalarial, the continuing development of resistance to current ... Antimalarial agents, Triazines, Guanidines, Chlorobenzenes, All stub articles, Antiinfective agent stubs). ...
Biot C, Nosten F, Fraisse L, Ter-Minassian D, Khalife J, Dive D (August 2011). "The antimalarial ferroquine: from bench to ... Roux C, Biot C (April 2012). "Ferrocene-based antimalarials". Future Medicinal Chemistry. 4 (6): 783-797. doi:10.4155/fmc.12.26 ... an antimalarial, which has reached Phase IIb trials. Ferrocene-containing polymer-based drug delivery systems have been ... new generation of antimalarial agents". European Journal of Medicinal Chemistry. 101: 534-551. doi:10.1016/j.ejmech.2015.07.009 ...
Programmes which presumptively treat all causes of fever with antimalarial drugs may lead to overuse of antimalarials and ... Antimalarial mass drug administration to an entire population at the same time may reduce the risk of contracting malaria in ... Antimalarial drugs using synthetic metal-based complexes are attracting research interest. (+)-SJ733: Part of a wider class of ... This is due to the cost of the drugs, side effects from long-term use, and the difficulty in obtaining antimalarial drugs ...
... is an antimalarial lactone derived from qinghao (青蒿, Artemisia annua or sweet wormwood). In 1596, Li Shizhen ... This second source of artemisinin is poised to enable a more stable flow of key antimalarial treatments to those who need them ... These metabolites lack antimalarial properties due to the loss of the endoperoxide group (deoxyartemisinin however has anti- ... "Development of Novel Antimalarials". MalariaWorld. September 6, 2010. Retrieved 2016-10-22. "WHO calls for an immediate halt to ...
Fieser, Louis F.; Fieser, Mary (1948), "Naphthoquinone Antimalarials. XII. The Hooker Oxidation Reaction", J. Am. Chem. Soc., ... and the antimalarial compound lapinone. However the Fiesers were best known for their numerous books. Their first joint ...
Suarez-Almazor ME, Belseck E, Shea B, Homik J, Wells G, Tugwell P (2000). "Antimalarials for treating rheumatoid arthritis". ...
"Research focuses on traditional antimalarials". Archived from the original on July 19, 2009. Retrieved 4 December 2016. " ... 2013-02-03 at the Wayback Machine On the First International Meeting of the Research Initiative on Traditional Antimalarial ...
Antimalarial Drugs. Washington, DC: National Research Council, Office of Medical Information, 1944 (co-author). Soranus' ...
Attempts to find new antimalarials. Part XXIV. Derivatives of o-phenanthroline (7 : 8 : 3′ : 2′-pyridoquinoline)". J. Chem. Soc ...
Kim, Jeong Joo; Hibbs, Ryan E. (2019). "Bridges between Antimalarials and Synaptic Transmission". Neuron. Cell Press. 101 (4): ...
Nwokolo C (October 1965). "Prophylactic antimalarials in sickle-cell disease". British Medical Journal. 2 (5466): 880. doi: ...
Artemisinin, an antimalarial agent from sweet wormtree Artemisia annua, used in Chinese medicine since 200BC is one drug used ... an anti-malarial; an anti-bacterial; and a treatment for gout. Cloning of human proteins made possible the screening of large ...
It remained the antimalarial drug of choice until the 1940s, when other drugs took over. The form of quinine most effective in ... Quinine remained the antimalarial drug of choice until after World War II. Since then, other drugs that have fewer side effects ... May 2011). "Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria". Malaria Journal. 10: 144. ... Tonic water was initially marketed as a means of delivering quinine to consumers in order to offer anti-malarial protection. ...
Low doses of antimalarials can be used. Orally ingested chloroquine is completely absorbed in the gut and is preferentially ... Complete remission can be seen within 6-12 months as each dose of antimalarial can only remove a finite amount of porphyrins ... "Interaction of quinoline antimalarial drugs with ferriprotoporphyrin IX, a solid state spectroscopy study". Journal of ... Protoporphyrin IX Complexes of the Antimalarial Cinchona Alkaloids Quinine and Quinidine". ACS Chemical Biology. 7 (4): 666-71 ...
... received renewed attention for its wide range of biological activities, including activities as antimalarial, ... Castro, A. J. (1967). "Antimalarial Activity of Prodigiosin". Nature. 213 (5079): 903-904. Bibcode:1967Natur.213..903C. doi: ...
Osorio is a Data Access Committee member of the Worldwide Antimalarial Resistance Network (WWARN). As part of the WWARN's ... "Dr Lyda Osorio". Worldwide Antimalarial Resistance Network. 2017-04-11. Retrieved 2021-04-07. WWARN Gametocyte Study Group (May ...
"Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive ... Worldwide Antimalarial Resistance Network. Archived (PDF) from the original on 2022-10-09. Retrieved 2017-01-20. Brockman, A.; ...
2) Antimalarial Drug Action. For example, Tilley investigates the molecular basis of the resistance that is currently emerging ... to the antimalarial drug, artemisinin, with a view to extending the use of a drug that saves millions of lives, 3) Studying the ... "Tilley laboratory: Measuring and modelling malaria parasites to develop new antimalarials". 13 December 2018. http://www. ...
Worldwide Antimalarial Resistance Network (WWARN) (2016-01-28). "Malaria in Pregnancy Consortium". Worldwide Antimalarial ... Some of the antimalarial drugs used include Chloroquine, Mefloquine, and Sulfadoxine/pyrimethamine since they are safe for use ... Prevention of pregnancy-associated malaria can be done with the use of various antimalarial drugs that are given before or ... This gene is important in determining if certain antimalarial drugs such as Primaquine and Tafenoquine can be used since these ...
He coordinates clinical trials for antimalarials in Western Africa. He led the trail of pyramax, which he showed could be used ... Djimdé helped to establish the Worldwide Antimalarial Resistance Network and served on the advisory board. In 2012 he was ... He works on the genetic epidemiology of antimalarial drug resistance and is a Wellcome Sanger Institute International Fellow. ... Worldwide Antimalarial Resistance Network". www.wwarn.org. 29 January 2015. Retrieved 2018-06-10. "Honors and award , DELGEME ...
"New antimalarial trioxanes and endoperoxides". Antimalarial Chemotherapy: 255-263.{{cite journal}}: CS1 maint: multiple names: ... a hypothetical compound whose skeleton occurs as a structural element of some antimalarial agents (artemisinin and similar ...
As with other quinoline antimalarial drugs, the antimalarial mechanism of action of quinine has not been fully resolved. The ... Antimalarials are lipophilic weak bases and easily pass plasma membranes. The free base form accumulates in lysosomes (acidic ... Mefloquine and other drugs known to lower the seizure threshold (co-administration with other antimalarials known to lower the ... After World War I, the German government sought alternatives to quinine as an anti-malarial. Chloroquine, a synthetic analogue ...
Cases of homeopaths advising against the use of anti-malarial drugs have also been identified, putting visitors to the tropics ... Coffman, Becky (January 28, 2019). "A cautionary tale: the risks of unproven antimalarials". Centers for Disease Control. Pray ...
Cases of homeopaths advising against the use of anti-malarial drugs have been identified. This puts visitors to the tropics who ... Coffman, Becky (January 28, 2019). "A cautionary tale: the risks of unproven antimalarials". Centers for Disease Control. ...
January 2021). "Repurposing Antimalarials to Tackle the COVID-19 Pandemic". Trends in Parasitology. 37 (1): 8-11. doi:10.1016/j ... Li G, Li Y, Li Z, Zeng M (28 November 2017). Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese ... Artesunate-based regimens are less likely to cause vomiting and tinnitus than quinine plus anti-malarial antibiotic therapy. ... Antimalarial agents, Carboxylate esters, Organic peroxides, Orphan drugs, Sesquiterpenes, Trioxanes, World Health Organization ...
... is an antimalarial drug. It was first made in 1970 and has been in clinical use in China since the 1980s. In a ... Chang C, Lin-Hua T, Jantanavivat C (1992). "Studies on a new antimalarial compound: pyronaridine". Transactions of the Royal ... August 2012). "Review of pyronaridine anti-malarial properties and product characteristics". Malaria Journal. 11: 270. doi: ... November 2019). "Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection". PLOS ...