Formally, amidines are a class of oxoacids. The oxoacid from which an amidine is derived must be of the form RnE(=O)OH, where R ... Examples of amidines include: DBU diminazene benzamidine Pentamidine Paranyline A common route to primary amidines is the ... Dimethylformamide acetal reacts with primary amines to give amidines: Me2NC(H)(OMe)2 + RNH2 → Me2NC=NHR + 2 MeOH Amidines are ... Carboxamidines are frequently referred to simply as amidines, as they are the most commonly encountered type of amidine in ...

... s can be alternatively formed in a one-pot process using the Graham reaction, starting from amidines. This reaction ... Graham, W. H. (1965-10-01). "The Halogenation of Amidines. I. Synthesis of 3-Halo- and Other Negatively Substituted Diazirines1 ...

Amidine substrates for the reaction can easily be formed from the corresponding nitriles via the Pinner reaction. The halide ... In organic chemistry, the Graham reaction is an oxidation reaction that converts an amidine into a diazirine using a hypohalite ... v t e (All stub articles, Organic chemistry stubs, Ring forming reactions, Organic oxidation reactions, Amidines, Diazirines). ... Graham, W. H. (1965-10-01). "The Halogenation of Amidines. I. Synthesis of 3-Halo- and Other Negatively Substituted Diazirines ...

It is the simplest aryl amidine. The compound is a white solid that is slightly soluble in water. It is usually handled as the ... Aromatic Amidines as Competitive Inhibitors of Trypsin". The Journal of Biochemistry. 69 (5): 893-899. doi:10.1093/ ... Amidines, All stub articles, Organic compound stubs). ...

Common superbases of this variety feature amidine, guanidine, and phosphazene functional groups. Strong superbases can be ... These include the phosphazenes, phosphanes, amidines, and guanidines. Other organic compounds that meet the physicochemical or ...

"Amidines Derived from Pt(IV)-Mediated Nitrile−Amino Alcohol Coupling and Their Zn(II)-Catalyzed Conversion into Oxazolines". ... preceding via an intermediate amidine. Limited research has been done into identifying alternative solvents or catalysts for ...

Reaction of the former with amidines to give 2-substituted pyrimidines, with urea to give 2-pyrimidinones, and guanidines to ... Pinner, A. (1884). "Ueber die Einwirkung von Acetessigäther auf die Amidine" [On the effect of acetylacetonate ester on ... Pinner, A. (1885). "Ueber die Einwirkung von Acetessigäther auf die Amidine. Pyrimidin" [On the effect of acetylacetonate ester ... who synthesized derivatives by condensing ethyl acetoacetate with amidines. Pinner first proposed the name "pyrimidin" in 1885 ...

MOSC1 has been reported to reduce amidoximes to amidines. Genetic variation in MARC1 has been reported to be associated with ...

The Pinner triazine synthesis describes the preparation of 2-hydroxyl-4,6-diaryl-s-triazines by reaction of aryl amidines and ... This reaction may be extended to halogenated aliphatic amidines. This reaction was first reported by Adolf Pinner in 1890 H. ...

Amidine Guanidines Pinner, A. (January 1883). "Ueber die Umwandlung der Nitrile in Imide. Verhalten der Blausäure und des ...

doi:10.1007/s10765-019-2540-2. Ishikawa, T. (2009). Superbases for Organic Synthesis: Guanidines, Amidines, Phosphazenes and ...

They can be hydrolyzed to give esters and by an analogous process react with amines (including ammonia) to form amidines. ... Amidines Esters Oxazoline - the corresponding 5-membered heterocycle "Pinner Reaction". Organic Chemistry Portal. Buckten, CH: ...

Amidine protecting groups for oligonucleotide synthesis". J. Am. Chem. Soc. 108 (8): 2040-2048. doi:10.1021/ja00268a052. Guzaev ...

Amidine protecting groups for oligonucleotide synthesis". J. Am. Chem. Soc. 108 (8): 2040. doi:10.1021/ja00268a052. Sinha, N. D ...

Thus, leading to the formation of thiomidates, imidates and amidines respectively. The nitrile group of OLT1177 is still not ...

A Convenient Route to Imidates and Amidine Salts". Journal of Organic Chemistry. 26 (2): 412. doi:10.1021/jo01061a034. ( ... With an excess of alcohol to form an orthoester With ammonia or an amine to form an amidine (di-nitriles may form imidines, for ...

A Convenient Route to Imidates and Amidine Salts". The Journal of Organic Chemistry. 26 (2): 412-418. doi:10.1021/jo01061a034. ...

The sub-sub-class refers to the type of substrate the enzyme is binding to, in this case, cyclic amidines. The final number (17 ... This pathway is referred to as amidine hydrolysis. Adenosine-phosphate deaminase binds to 5'-AMP using water to break the C-N ... specifically in cyclic amidines. The systematic name of this enzyme class is adenosine-phosphate aminohydrolase. Other names in ...

It belongs to the class of pyrrole-amidine antibiotics. Netropsin binds to the minor groove of AT-rich sequences of double ... Amidines, Guanidines, Antibiotics, DNA-binding substances, Imidazoles). ...

It is an amidine base used in organic synthesis. A related compound with related functions is 1,8-diazabicyclo[5.4.0]undec-7- ... doi:10.1002/anie.196700761 Oediger, H., Möller, F., & Eiter, K. "Bicyclic Amidines as Reagents in Organic Syntheses" Synthesis ...

They are stronger bases than regular amine or amidine bases. Protonation takes place at a doubly bonded nitrogen atom. Related ... Amidines, Phosphazenes and Related Organocatalysts Tsutomu Ishikawa ISBN 978-0-470-51800-7 Saame, Jaan; Rodima, Toomas; ...

... is an amidine which serves as a serotonin inhibitor. This agent is prepared by alkylation of 3-methoxyphenol (m- ... Amidines, Peripherally selective drugs, All stub articles, Nervous system drug stubs). ...

Quantum-chemical calculations concerning the spontaneous rearrangement of the adduct into ring-contracted amidines". ...

The amidine formed with 2-naphthylamine and the dimethyl sulfate adduct can be cyclized with sodium methoxide to give benzo[f] ... Therefore, 3-dimethylaminoacrolein and vinamidines derived therefrom (composed of vinylogous amidines) or vinamidinium salts ( ... "Synthese und Reaktionen vinyloger Amidacetale und Amidine", Angew. Chem. (in German), vol. 77, no. 5, p. 219, doi:10.1002/ange. ... be easily transformed with nucleophiles such as alkoxides or amines into the corresponding vinylogous amide acetals or amidines ...

4-Imidazolones arise from the condensation of amidines with 1,2-dicarbonyls such as glyoxal. Bellier, Justine; Nokin, Marie- ...

degree with a dissertation entitled „The Involvement of Cytochrome P450 in the Biotransformation of Amidines; Investigation ...

Alternatively, sulfur dichloride reacts with amidines to give dithiadiazolium chlorides, albeit with sensitivity to reaction ... 192-194 Dithiadiazolium salts hydrolyze to amidine-hydrochloride salts, sulfur dioxide, and elemental sulfur.: 171 ...

C.G. Jaffredo; J.-F. Carpentier; S.M. Guillaume (2012). "Controlled ROP of β-butyrolactone simply mediated by amidine, ...

Thio thionamide is even more prone to amidine formation than the lactam itself. Reaction of thionamide (2) with O-allyl- ...

Bottromycins contain a C-terminal decarboxylated thiazole in addition to a macrocyclic amidine. There are currently six known ...