Adenine nucleotide translocator
Adenine+Nucleotide+Translocator+2 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Adenine+Nucleotide+ ... Adenine nucleotide translocator (ANT), also known as the ADP/ATP translocase (ANT), ADP/ATP carrier protein (AAC) or ... Adenine+Nucleotide+Translocator+1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ... Pressman BC (June 1958). "Intramitochondrial nucleotides. I. Some factors affecting net interconversions of adenine nucleotides ...
Apoptosis regulator BAX
"Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis". Science. 281 (5385): 2027-31. ... In addition, it can become activated by binding BCL-2, as well as non-BCL-2 proteins such as p53 and Bif-1. Conversely, BAX can ... Weng C, Li Y, Xu D, Shi Y, Tang H (March 2005). "Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related ... 307 (1): 70-5. doi:10.1016/S0003-2697(02)00028-3. PMID 12137781. Gillissen B, Essmann F, Graupner V, Stärck L, Radetzki S, ...
BCL2L13
Kim JY, So KJ, Lee S, Park JH (Sep 2012). "Bcl-rambo induces apoptosis via interaction with the adenine nucleotide translocator ... Bcl-rambo mediates apoptosis by associating with adenine nucleotide translocator (ANT), a component of the mitochondrial ... 34 (1): 18-23. doi:10.1016/j.leukres.2009.07.023. PMID 20109966. Jensen SA, Calvert AE, Volpert G, Kouri FM, Hurley LA, Luciano ... 534 (1-3): 61-8. doi:10.1016/S0014-5793(02)03778-X. PMID 12527362. S2CID 7018829. Human BCL2L13 genome location and BCL2L13 ...
Sengers syndrome
AGK gene encodes the mitochondrial acylglycerol kinase which plays a role in the assembly of adenine nucleotide translocator. ... The SLC25A4 gene encodes the heart and muscle-specific isoform 1 of the mitochondrial adenine nucleotide translocator. The ...
CYC1
"Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR ... Nishikimi M, Ohta S, Suzuki H, Tanaka T, Kikkawa F, Tanaka M, Kagawa Y, Ozawa T (April 1988). "Nucleotide sequence of a cDNA ... 200 (1-2): 149-56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. Valnot I, Kassis J, Chretien D, de Lonlay P, Parfait B, ... 19 (2): 400-1. doi:10.1006/geno.1994.1084. PMID 8188279. Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S ( ...
AGK (gene)
AGK also has an implicated role in the assembly of the adenine nucleotide translocator in the inner mitochondrial membrane. ... 108 (1): 40-50. doi:10.1016/j.ymgme.2012.11.282. PMID 23266196. Nouh MA, Wu XX, Okazoe H, Tsunemori H, Haba R, Abou-Zeid AM, ... ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate. The enzyme is involved in the more general pathway of ... 138 (1-2): 171-4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano ...
Jerzy Duszyński (biochemist)
1982). "Quantification of the role of the adenine nucleotide translocator in the control of mitochondrial respiration in ... The first quantification of the controlling weight of adenine nucleotide transport in cellular bioenergetics. Quantification of ... doi:10.1016/S0021-9258(17)34592-1. PMID 681344. Duszynski, J.; et al. ( ... 1 year, including in Grenoble). The course of his scientific career has been closely linked to the Nencki Institute of ...
Bongkrek acid
Adenine nucleotide translocator, abbreviated as ANT, provides ATP from mitochondria to the cytosol in exchanging of cytosolic ... Henderson, P. J. F.; Lardy, H. A. (1970). "Bongkrekic Acid: An Inhibitor of Adenine Nucleotide Translocase of Mitochondria" ( ... preventing the binding of adenosine nucleotides. This means ANT can't receive ADP from the cytosol, ultimately preventing the ... A fatal dose for humans can be as low as 1 to 1.5 mg, and other source also states that oral LD50 is 3.16 mg per kg body weight ...
List of MeSH codes (D12.776)
... adenine nucleotide translocator 2 MeSH D12.776.575.750.500.300 - adenine nucleotide translocator 3 MeSH D12.776.580.210.175.325 ... adenine nucleotide translocator 1 MeSH D12.776.575.750.500.200 - ... neuregulin-1 See List of MeSH codes (D12.776.476). MeSH D12.776 ... cofilin 1 MeSH D12.776.220.525.212.750 - cofilin 2 MeSH D12.776.220.525.212.875 - destrin MeSH D12.776.220.525.246.500 - actin- ... hiv-1 reverse transcriptase MeSH D12.776.964.970.880.325 - gene products, env MeSH D12.776.964.970.880.325.330 - hiv envelope ...
ANT1 (disambiguation)
... adenine nucleotide translocator 1) is the most abundant protein in the inner mitochondrial membrane. It is an enzyme that in ...
List of MeSH codes (D12.776.157)
... adenine nucleotide translocator 2 MeSH D12.776.157.530.625.875.500.300 - adenine nucleotide translocator 3 MeSH D12.776.157.530 ... adenine nucleotide translocator 1 MeSH D12.776.157.530.625.875.500.200 - ... nucleotide transport proteins MeSH D12.776.157.530.625.875.500 - mitochondrial adp, atp translocases MeSH D12.776.157.530. ... aryl hydrocarbon receptor nuclear translocator MeSH D12.776.157.530.750.200 - cellular apoptosis susceptibility protein MeSH ...
Y linkage
... adenine nucleotide translocator-3 on the Y), AZF2 (azoospermia factor 2), BPY2 (basic protein on the Y chromosome), AZF1 ( ... family 1, member A1), RBM2 (RNA binding motif protein 2), and UTY (ubiquitously transcribed TPR gene on Y chromosome). USP9Y ... azoospermia factor 1), DAZ (Spermatogenes is deleted in azoospermia), RBM1 (RNA binding motif protein, Y chromosome, ...
List of MeSH codes (D12.776.543)
... adenine nucleotide translocator 2 MeSH D12.776.543.585.450.162.235.300 - adenine nucleotide translocator 3 MeSH D12.776.543.585 ... adenine nucleotide translocator 2 MeSH D12.776.543.585.625.875.500.300 - adenine nucleotide translocator 3 MeSH D12.776.543.585 ... adenine nucleotide translocator 1 MeSH D12.776.543.585.450.162.235.200 - ... adenine nucleotide translocator 1 MeSH D12.776.543.585.625.875.500.200 - ...
Ant (disambiguation)
... an approach to social theory and research Adenine nucleotide translocator Anacamptis (abbreviation Ant), a genus of orchids ... ISO 3166-1 alpha-3 country code) River Ant, a river in Norfolk, England ANT (network), a wireless personal area network ...
Thermogenin
UCP1 is very similar to the ATP/ADP Carrier protein, or Adenine Nucleotide Translocator (ANT). The proposed alternating access ... UCP1 is related to other mitochondrial metabolite transporters such as the adenine nucleotide translocator, a proton channel in ... UCP1 is activated in the brown fat cell by fatty acids and inhibited by nucleotides. Fatty acids are released by the following ... overriding the inhibition caused by purine nucleotides (GDP and ADP). During the termination of thermogenesis, thermogenin is ...
ARHGAP11B
... where it binds to the adenine nucleotide translocator. It does not affect the adenine nucleotide exchange activity of the ... A 2016 study suggests, one mutation, a "single nucleotide substitution underlies the specific properties of ARHGAP11B that ... translocator, but it does lead to delayed opening of the mitochondrial permeability transition pore, thus allowing for greater ... In contrast to full-length ARHGAP11A and ARHGAP11A 1-250, ARHGAP11B, like ARHGAP11A1-220, did not exhibit RhoGAP activity in a ...
Apoptosome
... the inner membrane protein adenine nucleotide translocator (AdNT) and the matrix protein cyclophilin D (CyD) (12). This pore ... It has also been shown that the nucleotide dATP as third component binds to apaf-1, however its exact role is still debated. ... A short linker and nucleotide binding a/b domains (NBD) that contain conserved Walker boxes A (p-loop 155-161) and B (239-243) ... a central nucleotide-binding and oligomerization region (NB-ARC/NOD, 128-586) and a C-terminal WD40 region (613-1248) making up ...
MT-TT
... myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator". ... MT-TT is a small 66 nucleotide RNA (human mitochondrial map position 15888-15953) that transfers the amino acid threonine to a ... 225 (1): 180-5. doi:10.1006/bbrc.1996.1150. PMID 8769114. This article incorporates text from the United States National ...
TXN2
... thiols in the mitochondrial permeability transition pore component adenine nucleotide translocator (ANT). Overexpression of ... "Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer". Cancer Research. ... 465 (1): 119-26. doi:10.1016/j.abb.2007.05.001. PMID 17548047. Oestergaard MZ, Tyrer J, Cebrian A, Shah M, Dunning AM, Ponder ... Zhou J, Damdimopoulos AE, Spyrou G, Brüne B (Mar 2007). "Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on ...
Substrate-level phosphorylation
... but also to prevent mitochondria from straining glycolytic ATP reserves by maintaining the adenine nucleotide translocator in ' ... "Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level ... "Expression of two succinyl-CoA synthetases with different nucleotide specificities in mammalian tissues". The Journal of ... 1,3-bisphosphoglycerate is then dephosphorylated via phosphoglycerate kinase, producing 3-phosphoglycerate and ATP through a ...
Mitochondrion
ROS increases uncoupling proteins (UCPs) and potentiate proton leakage through the adenine nucleotide translocator (ANT), the ... One of the two mitochondrial DNA (mtDNA) strands has a disproportionately higher ratio of the heavier nucleotides adenine and ... Nachman MW, Crowell SL (September 2000). "Estimate of the mutation rate per nucleotide in humans". Genetics. 156 (1): 297-304. ... Tumor cells require ample ATP to synthesize bioactive compounds such as lipids, proteins, and nucleotides for rapid ...
Membrane transport protein
Adenine nucleotide translocator (ANT) 2.B: Nonribosomally synthesized porters, such as: The Nigericin family The Ionomycin ... such as rhodopsin The group translocators provide a special mechanism for the phosphorylation of sugars as they are transported ... ISBN 1-4292-1962-9. p. 119. Cooper, Geoffrey (2009). The Cell: A Molecular Approach. Washington, DC: ASM Press. p. 62. ISBN ... ISBN 1-4292-1962-9. p. 119. Ashley, Ruth. Hann, Gary. Han, Seong S. Cell Biology. New Age International Publishers. ISBN ...
Mitochondrial carrier
SLC25A25 adenine nucleotide - SLC25A4, SLC25A5, SLC25A6, SLC25A31 dicarboxylate - SLC25A10 oxoglutarate - SLC25A11 glutamate - ... "Site-directed mutagenesis of the yeast mitochondrial ADP/ATP translocator. Six arginines and one lysine are essential". Journal ... Mitochondrial carriers transport amino acids, keto acids, nucleotides, inorganic ions and co-factors through the mitochondrial ... nucleotides, amino acids, keto acids and cofactors across the membrane. Such proteins include: ADP/ATP carrier protein (ADP-ATP ...
Mitochondrial permeability transition pore
Further hypothesis by Halestrap's group convincingly suggested the MPT was formed by the inner membrane Adenine Nucleotide ... "The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore". Nature. 427 (6973): 461-465. ... "The nature of the calcium ion efflux induced in rat liver mitochondria by the oxidation of endogenous nicotinamide nucleotides ... "Regulation of the Inner Membrane Mitochondrial Permeability Transition by the Outer Membrane Translocator Protein (Peripheral ...