... , ATF, is a group of bZIP transcription factors, which act as homodimers or heterodimers with a ... biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors ... Activating+Transcription+Factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles with ... activating transcription factor proteins and homeostasis". Gene. 273 (1): 1-11. doi:10.1016/S0378-1119(01)00551-0. ISSN 0378- ...

... , also known as ATF2, is a protein that, in humans, is encoded by the ATF2 gene. This gene ... "Entrez Gene: ATF2 activating transcription factor 2". Ozawa K, Sudo T, Soeda E, Yoshida MC, Ishii S (1991). "Assignment of the ... Activating transcription factor 2 has been shown to interact with C-jun, Casein kinase 2, alpha 1, CREB binding protein, ... "Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in ...

"Activating Transcription Factor 7 Interacting Protein". Retrieved 23 April 2011. "AceView: Homo sapiens complex locus QRICH1, ... Interacting Proteins: ATXN1, Spinocerebellar ataxia type 1 protein, and ATF7IP, activating transcription factor 7-interacting ... ATF7IP is a recruiter protein that couples transcriptional factors to the general transcription apparatus, thereby modulating ... transcription regulation and chromatin formation. QRICH1 is expressed at a high level, 3.3 times the average gene. It is ...

"Entrez Gene: ATF7 activating transcription factor 7". Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006 ... a novel variant of the ATF/CREB transcription factor family, forms a dominant transcription inhibitor in ATF-a heterodimers". J ... Cyclic AMP-dependent transcription factor ATF-7 is a protein that in humans is encoded by the ATF7 gene. In 2001, Peters et al ... Transcription factors, All stub articles, Human chromosome 12 gene stubs). ...

"Entrez Gene: ATF1 activating transcription factor 1". Zucman J, Delattre O, Desmaze C, Epstein AL, Stenman G, Speleman F, ... 1993). "Activating transcription factor-1 can mediate Ca(2+)- and cAMP-inducible transcriptional activation". J. Biol. Chem. ... Sun P, Lou L, Maurer RA (1996). "Regulation of activating transcription factor-1 and the cAMP response element-binding protein ... This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper ...

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding ... ATF3 activating transcription factor 3". Chen BP, Wolfgang CD, Hai T (March 1996). "Analysis of ATF3, a transcription factor ... Activating transcription factor ATF3 has been shown to interact with: C-jun, DDIT3 JunD, P53, and SMAD3. GRCh38: Ensembl ... Chu HM, Tan Y, Kobierski LA, Balsam LB, Comb MJ (January 1994). "Activating transcription factor-3 stimulates 3',5'-cyclic ...

"Distinct Roles of Transcription Factors KLF4, Krox20, and Peroxisome Proliferator-Activated Receptor γ in Adipogenesis". ... Kim JH, Song J, Park KW (March 2015). "The multifaceted factor peroxisome proliferator-activated receptor γ (PPARγ) in ... is a type II nuclear receptor functioning as a transcription factor that in humans is encoded by the PPARG gene. PPARG is ... "Activation of PPARgamma coactivator-1 through transcription factor docking". Science. 286 (5443): 1368-71. doi:10.1126/science. ...

"Entrez Gene: transcription factor AP-2 beta (activating enhancer binding protein 2 beta)". Tsukada S, Tanaka Y, Maegawa H, et ... 2006). "Transcription factor activating enhancer-binding protein-2beta. A negative regulator of adiponectin gene expression". J ... Transcription factor AP-2 beta also known as AP2-beta is a protein that in humans is encoded by the TFAP2B gene. AP-2 beta is a ... 2009). "The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents". Obesity ( ...

Activating transcription factor 7-interacting protein 1 is a protein that in humans is encoded by the ATF7IP gene. ATF7IP has ... "Entrez Gene: ATF7IP activating transcription factor 7 interacting protein". Fujita, Naoyuki; Watanabe Sugiko; Ichimura Takaya; ... PDBe-KB provides an overview of all the structure information available in the PDB for Human Activating transcription factor 7- ... Gunther M, Laithier M, Brison O (Dec 2000). "A set of proteins interacting with transcription factor Sp1 identified in a two- ...

"The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription". The EMBO Journal. 21 (3): 451-60. doi: ... nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ... as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor". The ... Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, ...

March 1995). "Cdk-activating kinase complex is a component of human transcription factor TFIIH". Nature. 374 (6519): 283-7. ... March 1995). "Cdk-activating kinase complex is a component of human transcription factor TFIIH". Nature. 374 (6519): 283-7. ... "From androgen receptor to the general transcription factor TFIIH. Identification of cdk activating kinase (CAK) as an androgen ... "Association of Cdk-activating kinase subunits with transcription factor TFIIH". Nature. 374 (6519): 280-2. Bibcode:1995Natur. ...

P-TEFb also phosphorylates and activates SPT5 and TAT-SF1. SPT5 is a universal transcription factor that helps recruit 5'- ... General transcription factors are a group of proteins involved in transcription initiation and regulation. These factors ... The transcription, a complete set of general transcription factors and RNA polymerase need to be assembled at the core promoter ... After escaping the promoter and shedding most of the transcription factors for initiation, the polymerase acquires new factors ...

It is hypothesized that VegT also activates the Xnr-1,2,4 proteins. VegT acts as a transcription factor to activate genes ... These transcription factors regulate other transcription factors, cell surface molecules with roles in cell adhesion, and other ... β-catenin activates the transcription factor stat3. Stat3 coordinates cell movements during gastrulation and contributes to ... β-catenin in the nucleus activates two transcription factors: siamois and twin. β-catenin also acts synergistically with VegT ...

The inflammatory transcription factor NF-κB and CD38 are mutually activating. Secretions from senescent cells induce high ... As a receptor, CD38 can attach to CD31 on the surface of T cells, thereby activating those cells to produce a variety of ... Zhao ZY, Xie XJ, Li WH, Zhao YJ (2016). "A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce ... The cytokine tumor necrosis factor strongly induces CD38 on airway smooth muscle cells inducing cADPR-mediated Ca2+, thereby ...

... shows decreased expression when activating transcription factor 2 (ATF2) is knocked out. Since ATF2 was not predicted to ... "Suppressor role of activating transcription factor 2 (ATF2) in skin cancer". Proc. Natl. Acad. Sci. U.S.A. 105 (5): 1674-9. ...

V.; Seredenin, S. B. (September 2020). "Cognitive Enhancer Noopept Activates Transcription Factor HIF-1". Doklady Biochemistry ... In cell culture, cycloprolylglycine increases brain derived neurotrophic factor (BDNF). It has been evaluated for ... "Neuropeptide cycloprolylglycine increases the levels of brain-derived neurotrophic factor in neuronal cells". Doklady ... suggest that the pharmacological properties of Noopept are derived from its action as an activator of Hypoxia-inducible factor ...

FoxO transcription factors can activate expression of RICTOR. FoxO has been shown to inhibit mTORC1, while activating Akt ... to mediate the ubiquitination of growth-promoting factors cyclin E and c-Myc. Furthermore, elevated growth factor signaling may ... This phosphorylation activates Akt/PKB, where deregulation of Akt/PKB has been implicated in cancer and diabetes. RICTOR and ... Chen CC, Jeon SM, Bhaskar PT, Nogueira V, Sundararajan D, Tonic I, Park Y, Hay N (2010). "FoxOs inhibit mTORC1 and activate Akt ...

... is a transcription factor that assists in regulating cell growth. When activated, Pho4 is translocated to the nucleus. ... transcription factor. It is found in S. cerevisiae and other yeasts. It functions as a transcription factor to regulate ... Additionally, another transcription factor known as Pho2, binds to Pho4 and assists in Pho4's ability to bind tightly to its ... This completes the addition of the binding partners that Pho4 needs in order to be capable of acting as a transcription factor ...

These phosphorylated receptors in turn recruit STAT transcription factors which modulate gene transcription. The first JAK ... Many cytokines function by binding to and activating type I cytokine receptors and type II cytokine receptors. These receptors ... The committee also recommends using JAK inhibitors with caution in people with risk factors for blood clots in the lungs and in ... More specifically, Janus kinases phosphorylate activated cytokine receptors. ...

... which is in fact a transcription factor) binds to the DNA. The complex can inhibit or activate unknown genes. Chloracne, an ... However, there are not many studies on humans that assess the health risk factors of HpCDD. HpCDD seems to be more potent once ... but when DNA-synthesis is stimulated by epidermal growth factor, HpCDD acts as a co-mitogen. These effects are observed for ...

SREBF2- a transcription factor precursor which is imbedded in the endoplasmic reticulum membrane; activates genes involved with ...

AP-1 was first discovered as a TPA-activated transcription factor that bound to a cis-regulatory element of the human ... "The AP-1 transcription factor regulates breast cancer cell growth via cyclins and E2F factors". Oncogene. 27 (3): 366-77. doi: ... The AP-1 transcription factor has been shown to play numerous roles in cell growth and proliferation. In particular, c-Fos and ... AP-1 transcription factor has been shown to have a hand in a wide range of cellular processes, including cell growth, ...

ATF6 (activating transcription factor 6) is a basic leucine zipper transcription factor. Upon Grp78 dissociation, the entire ... is upregulated downstream of the bZIP transcription factor ATF4 (activating transcription factor 4) and uniquely responsive to ... The activated domain is able to activate the transcription factor XBP1(Xbox binding protein) mRNA (the mammalian equivalent of ... The activated transcription factor upregulates UPR 'stress genes' by directly binding to stress element promoters in the ...

... promoted β1 integrin expression by activating a transcription factor called SRF. A continually active form of the ... Activated Cdc42 activates by causing conformational changes in p21-activated kinases PAK1 and PAK2, which in turn initiate ... and it also modulates the transcription factors SRF, STAT3, and NFkB. It has been hypothesized that targeting Cdc42 in ... transcription factor was also capable of restoring endothelial insertion to cancer cells lacking Cdc42. Normal cancer cells and ...

"TFAP2C (transcription Factor AP-2 Gamma (activating Enhancer Binding Protein 2 Gamma))." TFAP2C (transcription Factor AP-2 ... AP2-gamma is a member of the activating protein 2 family of transcription factors. Transcription factor AP-2 gamma is involved ... "Transcription Factor AP-2 Gamma - TFAP2C - Homo sapiens (Human)." Transcription Factor AP-2 Gamma - TFAP2C - Homo sapiens ( ... Transcription factor AP-2 gamma also known as AP2-gamma is a protein that in humans is encoded by the TFAP2C gene. ...

"Cdk-activating kinase complex is a component of human transcription factor TFIIH". Nature. 374 (6519): 283-7. Bibcode:1995Natur ... "Cdk-activating kinase complex is a component of human transcription factor TFIIH". Nature. 374 (6519): 283-7. Bibcode:1995Natur ... General transcription factor IIH subunit 1 is a protein that in humans is encoded by the GTF2H1 gene. GTF2H1 has been shown to ... Tong X, Drapkin R, Reinberg D, Kieff E (1995). "The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction ...

Activating transcription factor 3 (Atf3) is a known RAG with numerous promoters. Atf3 expression increases after nerve injury ... Cis-regulatory elements in the promoter contain sequences recognized by transcription factors and the basal transcription ... For example, the same transcription factor (TF) can direct gene expression in different tissues simply by binding with ... predicting interaction between transcription factors in human tissues". Nucleic Acids Res. 34 (17): 4925-36. doi:10.1093/nar/ ...

Transcription factor AP-4 (activating enhancer binding protein 4), also known as TFAP4, is a protein which in humans is encoded ... Transcription factor AP4 is a member of the basic helix-loop-helix (bHLH) transcription factors, which bind to the E-box ... "Entrez Gene: TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)". Hu YF, Lüscher B, Admon A, et al. (1991 ... "Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro". Nature. 332 (6164): 557-61 ...

It was later identified by the yeast-two hybrid system to bind to activating transcription factor 2 (ATF2) to repress ATF- ... "Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in ... JDP2 (gene) has been shown to interact with Activating transcription factor 2. GRCh38: Ensembl release 89: ENSG00000140044 - ... c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter". ...

"Cdk-activating kinase complex is a component of human transcription factor TFIIH". Nature. 374 (6519): 283-7. Bibcode:1995Natur ... and the CDK-activating kinase (CAK) assembly factor MAT1 (MNAT1) to chromosome bands 5q13.3-q14 and 14q23, respectively". ... the fifth subunit of the core of the transcription/DNA repair factor TFIIH". The EMBO Journal. 16 (5): 1093-102. doi:10.1093/ ... a subunit of the human general transcription/DNA repair factor TFIIH". Protein Expression and Purification. 9 (2): 153-8. doi: ...

PPAR-α is a transcription factor regulated by free fatty acids, and is a major regulator of lipid metabolism in the liver. PPAR ... Rakhshandehroo M, Hooiveld G, Müller M, Kersten S (2009). "Comparative analysis of gene regulation by the transcription factor ... Together with peroxisome proliferator-activated receptor delta and peroxisome proliferator-activated receptor gamma, PPAR-alpha ... is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. ...