... , also known as ATF2, is a protein that, in humans, is encoded by the ATF2 gene. This gene ... "Entrez Gene: ATF2 activating transcription factor 2". Ozawa K, Sudo T, Soeda E, Yoshida MC, Ishii S (1991). "Assignment of the ... Activating transcription factor 2 has been shown to interact with C-jun, Casein kinase 2, alpha 1, CREB binding protein, ... "Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in ...
"Activating Transcription Factor 7 Interacting Protein". Retrieved 23 April 2011. "AceView: Homo sapiens complex locus QRICH1, ... Interacting Proteins: ATXN1, Spinocerebellar ataxia type 1 protein, and ATF7IP, activating transcription factor 7-interacting ... ATF7IP is a recruiter protein that couples transcriptional factors to the general transcription apparatus, thereby modulating ... transcription regulation and chromatin formation. QRICH1 is expressed at a high level, 3.3 times the average gene. It is ...
"Entrez Gene: ATF1 activating transcription factor 1". Zucman J, Delattre O, Desmaze C, Epstein AL, Stenman G, Speleman F, ... 1993). "Activating transcription factor-1 can mediate Ca(2+)- and cAMP-inducible transcriptional activation". J. Biol. Chem. ... Sun P, Lou L, Maurer RA (1996). "Regulation of activating transcription factor-1 and the cAMP response element-binding protein ... This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper ...
Transcription factor AP4 is a member of the basic helix-loop-helix (bHLH) transcription factors, which bind to the E-box ... activating enhancer binding protein 4), also known as TFAP4, is a protein which in humans is encoded by the TFAP4 gene. ... "Entrez Gene: TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)". Hu YF, Lüscher B, Admon A, et al. (1991 ... "Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity". Genes Dev. 4 (10): 1741-52. ...
"Entrez Gene: transcription factor AP-2 beta (activating enhancer binding protein 2 beta)". Tsukada S, Tanaka Y, Maegawa H, et ... 2006). "Transcription factor activating enhancer-binding protein-2beta. A negative regulator of adiponectin gene expression". J ... Transcription factor AP-2 beta also known as AP2-beta is a protein that in humans is encoded by the TFAP2B gene. AP-2 beta is a ... 2009). "The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents". Obesity ( ...
2005). "Mitosin/CENP-F as a negative regulator of activating transcription factor-4". J. Biol. Chem. 280 (14): 13973-7. doi: ... 13 (4): 275-83. doi:10.1038/sj.cr.7290172. PMID 12974617. Laoukili J, Kooistra MR, Brás A, et al. (2005). "FoxM1 is required ... 37 (4): 359-363. doi:10.1002/humu.22960. ISSN 1098-1004. PMID 26820108. S2CID 1495539. Human CENPF genome location and CENPF ... 37 (4): 359-363. doi:10.1002/humu.22960. ISSN 1098-1004. PMID 26820108. S2CID 1495539. "OMIM Entry - # 243605 - STROMME ...
Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding ... ATF3 activating transcription factor 3". Chen BP, Wolfgang CD, Hai T (March 1996). "Analysis of ATF3, a transcription factor ... Activating transcription factor ATF3 has been shown to interact with: C-jun, DDIT3 JunD, P53, and SMAD3. GRCh38: Ensembl ... Chu HM, Tan Y, Kobierski LA, Balsam LB, Comb MJ (January 1994). "Activating transcription factor-3 stimulates 3',5'-cyclic ...
"Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription". Cell. 96 (1): 143-52. doi: ... "Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription". Cell. 96 (1): 143-52. doi: ... Chu HM, Tan Y, Kobierski LA, Balsam LB, Comb MJ (January 1994). "Activating transcription factor-3 stimulates 3',5'-cyclic ... Chu HM, Tan Y, Kobierski LA, Balsam LB, Comb MJ (1994). "Activating transcription factor-3 stimulates 3',5'-cyclic adenosine ...
Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of ... Salgado MC, Metón I, Anemaet IG, Baanante IV (2014). "Activating transcription factor 4 mediates up-regulation of alanine ... 1839 (4): 288-96. doi:10.1016/j.bbagrm.2014.01.005. PMID 24418603. Celis K, Shuldiner S, Haverfield EV, Cappell J, Yang R, Gong ...
Zinc finger protein 521 (ZFP521) and activating transcription factor 4 (ATF4) are cofactors of Runx2. Binding of the ... Runt-related transcription factor 2 (RUNX2) also known as core-binding factor subunit alpha-1 (CBF-alpha-1) is a protein that ... This protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for ... RUNX2 is a key transcription factor associated with osteoblast differentiation. It has also been suggested that Runx2 plays a ...
Phosphorylated STAT6 dimerises and acts as a transcription factor activating many genes, such as eotaxin.[citation needed] ... only activates effectively STAT6. Activated STAT6 molecules form dimers which translocate to the nucleus to bind responsive ... Some recent works is evidencing how a wide range of signals can be actually activated by this receptor (e.g. WNT/β-Catenin, ... Xie M, Wu XJ, Zhang JJ, He CS (October 2015). "IL-13 receptor α2 is a negative prognostic factor in human lung cancer and ...
VegT acts as a transcription factor to activate genes specifying endodermal fate while Vg1 acts as a paracrine factor. β- ... These transcription factors regulate other transcription factors, cell surface molecules with roles in cell adhesion, and other ... β-catenin activates the transcription factor stat3. Stat3 coordinates cell movements during gastrulation and contributes to ... Low levels of dorsal can activate the transcription of rhomboid. Dorsal represses the transcription of zerknüllt, tolloid, and ...
Iizuka K, Horikawa Y (August 2008). "ChREBP: a glucose-activated transcription factor involved in the development of metabolic ... mainly by promoting the ChREBP transcription factor in the well-fed state. However, more recent study showed that D-glucose-6- ... Specifically, it activates protein phosphatase, which then dephosphorylates and inactivates the bifunctional enzyme. As a ... "Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver". ...
"Muscarinic acetylcholine receptors activate expression of the EGR gene family of transcription factors". The Journal of ... Mitchell R, Robertson DN, Holland PJ, Collins D, Lutz EM, Johnson MS (September 2003). "ADP-ribosylation factor-dependent ... 53 (4): 759-765. doi:10.1124/mol.53.4.759. PMID 9547368. von der Kammer H, Mayhaus M, Albrecht C, Enderich J, Wegner M, Nitsch ... 15 (4): 114-119. doi:10.1016/0165-6147(94)90047-7. PMID 8016895. Brann MR, Ellis J, Jørgensen H, Hill-Eubanks D, Jones SV (1994 ...
... can function either as an activating or an inhibitory transcription factor depending on its transcription cofactors. IRF4 ... IRF4 is a transcription factor belonging to the Interferon Regulatory Factor (IRF) family of transcription factors. In contrast ... April 1996). "A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the ... IRF4 is a transcription factor that has been implicated in acute leukemia. This gene is strongly associated with pigmentation: ...
Therefore, transcription factors are crucial for adipogenesis. Transcription factors, peroxis proliferator-activated receptor γ ... a lipid-activated transcription factor". Cell. 79 (7): 1147-56. doi:10.1016/0092-8674(94)90006-x. PMID 8001151. S2CID 54387527 ... other transcription factors function in the progression of differentiation. Adipocyte determination and differentiation factor ... C/EBPs, transcription factors, are members of the basic-leucine zipper class. cAMP, an inducer of adipogenesis, can promote ...
... a novel regulator for induction of activating transcription factor-2 and heme oxygenase-1". The Journal of Biological Chemistry ... by control of the upstream activator of insulin growth factor-1 (IGF-1) and mitogen-activated protein kinase (MAPK) signaling ... 269 (27): 17960-4. doi:10.1016/S0021-9258(17)32403-1. PMID 8027054. McDonagh AF, Palma LA, Schmid R (Jan 1981). "Reduction of ...
In a study by Razaghi et al, amino acid starvation activated the transcription factor Gcn4p, resulting in transcriptional ... Gcn4 is a highly conserved protein and its mammalian homolog is known as activating transcription factor-4 (ATF4). ... Gcn4 is a transcription factor and a "master regulator" for gene expression which regulates close to one tenth of the yeast ... DNA-binding protein Transcription factor Razaghi, Ali; Huerlimann, Roger; Owens, Leigh; Heimann, Kirsten (1 December 2015). " ...
Hsu SH, Hsieh-Li HM, Huang HY, Huang PH, Li H (May 2005). "bHLH-zip transcription factor Spz1 mediates mitogen-activated ...
"DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation". Molecular ... 31 (4): 409-16. doi:10.1007/s00774-013-0434-0. PMID 23525827. S2CID 22750579. Hartgers FC, Looman MW, van der Woning B, Merkx ...
"The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor". The Journal of ... The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription ... 7 (4): 273-81. doi:10.1093/dnares/7.4.271. PMID 10997877. Tang TT, Dowbenko D, Jackson A, Toney L, Lewin DA, Dent AL, Lasky LA ... 36 (4): 411-6. doi:10.1038/ng1321. PMID 15004558. Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA ...
... and activating transcription factor 3". Cancer Prevention Research. 4 (1): 116-27. doi:10.1158/1940-6207.CAPR-10-0218. PMC ... Black AR, Black JD, Azizkhan-Clifford J (August 2001). "Sp1 and krüppel-like factor family of transcription factors in cell ... gut-enriched Krüppel-like factor or GKLF) is a member of the KLF family of zinc finger transcription factors, which belongs to ... "Developmental and cell type-specific expression of the zinc finger transcription factor Krüppel-like factor 4 (Klf4) in ...
"Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia". ... An example of this includes the translocation of C-MYC, a gene that encodes a transcription factor that leads to increased cell ... Genetic risk factors may include Down syndrome, Li-Fraumeni syndrome, or neurofibromatosis type 1. Environmental risk factors ... Environmental risk factors are also needed to help create enough genetic mutations to cause disease. Evidence for the role of ...
"The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription". EMBO J. 21 (3): 451-60. doi:10.1093/ ... "The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription". EMBO J. 21 (3): 451-60. doi:10.1093/ ... and general transcription. DDX21 has been shown to interact with C-jun. GRCh38: Ensembl release 89: ENSG00000165732 - Ensembl, ... 281 (4): 1006-11. doi:10.1006/bbrc.2001.4446. PMID 11237763. Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, ...
"Virus Infection Induces the Assembly of Coordinately Activated Transcription Factors on the IFN-β Enhancer In Vivo". Molecular ... and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the ... Howley and his co-workers created gene maps of many species of papillomaviruses and analyzed their transcription patterns and ... 1 (4): 507-518. doi:10.1016/S1097-2765(00)80051-9. ISSN 1097-2765. PMID 9660935. Huang, L.; Kinnucan, E.; Wang, G.; Beaudenon, ...
"Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo". ... is a member of the interferon regulatory factor family of transcription factors. IRF7 encodes interferon regulatory factor 7, a ... "Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP ... "Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A ...
Transcription factor AP-2 alpha (Activating enhancer binding Protein 2 alpha), also known as TFAP2A, is a protein that in ... "Entrez Gene: TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)". Mitchell PJ, Wang C, Tjian ... Transcription factor AP-2 alpha is a 52-kD sequence-specific DNA-binding protein that enhances transcription of specific genes ... "RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2 ...
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 ... Tu N, Hu Y, Mivechi NF (2006). "Heat shock transcription factor (Hsf)-4b recruits Brg1 during the G1 phase of the cell cycle ... "Entrez Gene: HSF4 heat shock transcription factor 4". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace ... Transcription factors, All stub articles, Human chromosome 16 gene stubs). ...
Ji L, Arcinas M, Boxer LM (1995). "The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in ... Postel EH, Berberich SJ, Flint SJ, Ferrone CA (1993). "Human c-myc transcription factor PuF identified as nm23-H2 nucleoside ... Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally occurring transcripts (NME1-NME2) ... 17 (2): 522-4. doi:10.1006/geno.1993.1362. PMID 8406509. Engel M, Véron M, Theisinger B, Lacombe ML, Seib T, Dooley S, Welter C ...
This receptor can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. ... a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB". ... Tumor necrosis factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and ... "Tumor necrosis factor alpha (TNF-alpha) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells". Cell Growth ...
2002). "Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA". Nat. Genet. 31 (3): 289-94. doi: ... 2002). "Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA". Nat. Genet. 31 (3): 289-94. doi: ... 2002). "Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA". Nat. Genet. 31 (3): 289-94. doi: ... "Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) ...