"A novel glycosphingolipid-degrading enzyme cleaves the linkage between the oligosaccharide and ceramide of neutral and acidic ... glycosphingolipids". J. Biol. Chem. 261 (30): 14278-82. PMID 3771534. Portal: Biology v t e (EC 3.2.1, Enzymes of known ...

"Mushroom acidic glycosphingolipid induction of cytokine secretion from murine T cells and proliferation of NK1.1 α/β TCR-double ...

In the case of glycosphingolipids, exohydrolases acting at acidic pH optima cause the stepwise release of monosaccharide units ... Constitutive degradation of sphingolipids and glycosphingolipids takes place in the acidic subcellular compartments, the late ... such as sphingomyelin and the complex glycosphingolipids. ...

... s are a sub-class of the lipid class glycosphingolipid with three to nine sugar molecules as the side chain (or R ... a sugar with an acidic carboxy-group. However, some globosides with the core structure Cer-Glc-Gal-Gal do contain neuraminic ... When the globo-series glycosphingolipid (GSL) was reduced in the experiment the ERK signaling from the receptor tyrosine kinase ... acid, e.g. the globo-series glycosphingolipid "SSEA-4-antigen". The side chain can be cleaved by galactosidases and ...

During the digestive process of the bonnethead shark, the acidic stomach weakens the cell walls of the seagrass and allows for ... as it plays an important role in the degradation of glycosphingolipids. The enzyme will break down glucosylceramide into ... while the pH of a human's stomach is acidic (between 1.5 and 3.5). However, humans do require β-glucosidase, Lysosomal β- ...

... glycosphingolipids MeSH D09.400.410.420.025 - acidic glycosphingolipids MeSH D09.400.410.420.025.060 - antigens, cd15 MeSH ... neutral glycosphingolipids MeSH D09.400.410.420.525.200 - ceramides MeSH D09.400.410.420.525.200.250 - cerebrosides MeSH ...

... glycosphingolipids MeSH D10.570.877.360.025 - acidic glycosphingolipids MeSH D10.570.877.360.025.060 - antigens, cd15 MeSH ... acidic glycosphingolipids MeSH D10.390.470.025.060 - antigens, cd15 MeSH D10.390.470.025.475 - gangliosides MeSH D10.390. ... neutral glycosphingolipids MeSH D10.390.470.675.200 - ceramides MeSH D10.390.470.675.200.250 - cerebrosides MeSH D10.390. ... neutral glycosphingolipids MeSH D10.570.877.360.612.200 - ceramides MeSH D10.570.877.360.612.200.250 - cerebrosides MeSH ...

In the presence of psychosine, however, the levels of cAMP increased at a shifted, more acidic pH range. As such, psychosine ... as well as several other related glycosphingolipids. However, the specific binding of psychosine to GPR65 has been contested as ... It was found that overexpression of GPR65 prevents tumor cell death in acidic conditions in vitro and facilitates tumor growth ... After myocardial infarction, anaerobic respiration and severe inflammation occurs-both of which are accompanied by an acidic ...

The Lactosylceramides, also known as LacCer, are a class of glycosphingolipids composed of a variable hydrophobic ceramide ... Gaucher's disease is a sphingolipidosis described by a particular inadequacy in acidic glucocerebrosidase, which results in ... William W., Christie (10 January 2019). "Lactosylceramide and non-Acidic Oligoglycosylceramides". Retrieved 13 July 2019. {{ ...

An acidic pH (around 5.0) and low amounts of water make the epidermis hostile to many microorganic pathogens. Non-pathogenic ... For example glycosphingolipids become ceramides and phospholipids become free fatty acids. spinous layer (stratum spinosum) ... glycosphingolipids, free sterols, phospholipids and catabolic enzymes. Langerhans cells, immunologically active cells, are ...

Srinivas VR, Acharya S, Rawat S, Sharma V; Surolia A (2000). "The primary structure of the acidic lectin from winged bean ( ... Surolia has elucidated the role of glycosphingolipids as biological receptors through studies on lectin-glycolipid interactions ... Patanjali S.R., Sajjan S. U.; Surolia A. (1988). "Erythrocyte-binding studies on an acidic lectin from winged bean ( ...

However, this is only under acidic conditions not neutral conditions. To fully understand the role of sulfatide in the cycle of ... MAL forms complexes with sulfatide and other glycosphingolipids, and these complexes have been shown to play a role in apical ...

This could have immense effects on the signaling functions of ceramide because it is known that ceramide generated by acidic ... 2007). "Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide". Nature. 449 (7158): 62-67. Bibcode:2007Natur. ... In addition to their role as building blocks of biological membranes, glycosphingolipids have long attracted attention because ... Glucosylceramides (GluCer) are the most widely distributed glycosphingolipids in cells serving as precursors for the formation ...