... (GalNAc), is an amino sugar derivative of galactose. In humans it is the terminal carbohydrate forming ... N-Acetylgalactosamine is necessary for intercellular communication, and is concentrated in sensory nerve structures of both ... Destruction of Blood Group A Activity by an Enzyme from Clostridium tertium Which Deacetylates N-Acetylgalactosamine in Intact ... Media related to N-Acetylgalactosamine at Wikimedia Commons (Articles with short description, Short description matches ...
In enzymology, a N-acetylgalactosamine kinase (EC 2.7.1.157) is an enzyme that catalyzes the chemical reaction ATP + N-acetyl-D ... Other names in common use include GALK2, GK2, GalNAc kinase, and N-acetylgalactosamine (GalNAc)-1-phosphate kinase. Pastuszak I ... Thoden JB, Holden HM (2005). "The molecular architecture of human N-acetyl galactosamine kinase". J. Biol. Chem. 280 (38): ... Drake R, Elbein AD (1996). "Kidney N-acetylgalactosamine (GalNAc)-1-phosphate kinase, a new pathway of GalNAc activation". J. ...
N-acetylgalactosamine-6-sulfate sulfatase, and N-acetylgalactosamine 6-sulfatase. This enzyme participates in glycosaminoglycan ... The enzyme N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) catalyzes the chemical reaction of cleaving off the 6-sulfate groups ... Lim CT, Horwitz AL (1981). "Purification and properties of human N-acetylgalactosamine-6-sulfate sulfatase". Biochim. Biophys. ... Other names in common use include chondroitin sulfatase, chondroitinase, galactose-6-sulfate sulfatase, acetylgalactosamine 6- ...
... (EC 3.1.6.12, chondroitinsulfatase, chondroitinase, arylsulfatase B, acetylgalactosamine 4- ... N-acetylgalactosamine-4-sulfatase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC ... Tsuji M, Nakanishi Y, Habuchi H, Ishihara K, Suzuki S (April 1980). "The common identity of UDP-N-acetylgalactosamine 4- ... sulfatase, N-acetylgalactosamine 4-sulfate sulfohydrolase) is an enzyme with systematic name N-acetyl-D-galactosamine-4-sulfate ...
Galactosamine Globoside N-Acetylgalactosamine (N-Acetylglucosamine) GlcNAc "Uridine-diphosphate-n-acetylgalactosamine". pubchem ... and N-acetyl galactosamine (GalNAc). It is used by glycosyltransferases to transfer N-acetylgalactosamine residues to ... Uridine diphosphate N-acetylgalactosamine or UDP-GalNAc is a nucleotide sugar composed of uridine diphosphate (UDP) ...
... (EC 2.7.7.83) is an enzyme with systematic name UTP:N-acetyl-alpha-D-galactosamine-1- ... UDP-N-acetylgalactosamine+diphosphorylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: ...
In enzymology, a glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase (EC 2.4.1.122) is an enzyme that catalyzes the ...
In enzymology, an UDP-N-acetylgalactosamine-4-sulfate sulfotransferase (EC 2.8.2.7) is an enzyme that catalyzes the chemical ... uridine diphospho-N-acetylgalactosamine 4-sulfate sulfotransferase, and uridine diphosphoacetylgalactosamine 4-sulfate ... phosphosulfate to uridine diphosphate N-acetylgalactosamine 4-sulfate". J. Biol. Chem. 242 (9): 2288-90. PMID 6022874. Portal: ...
... (EC 2.8.2.33, GalNAc4S-6ST, CHST15 (gene)) is an enzyme with systematic ... N-acetylgalactosamine+4-sulfate+6-O-sulfotransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ... Ohtake S, Ito Y, Fukuta M, Habuchi O (November 2001). "Human N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase cDNA is ... CHST15 Ito Y, Habuchi O (November 2000). "Purification and characterization of N-acetylgalactosamine 4-sulfate 6-O- ...
N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol+4-alpha-N-acetylgalactosaminyltransferase at the U.S. ... N-acetylgalactosamine-N, N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase (EC 2.4. ...
Glaser L (November 1959). "The biosynthesis of N-acetylgalactosamine". The Journal of Biological Chemistry. 234 (11): 2801-5. ...
White square = N-acetyl-galactosamine; black circle = galactose; Black square = N-acetyl-glucosamine. Note: There is a mistake ... A Core 2 structure is generated by the addition of N-acetyl-glucosamine to the N-acetyl-galactosamine of the Core 1 structure. ... Core 3 structures are generated by the addition of a single N-acetyl-glucosamine to the original N-acetyl-galactosamine. Core 4 ... The first monosaccharide attached in the synthesis of O-linked glycans is N-acetyl-galactosamine. After this, several different ...
N-acetylgalactosamine-6-sulfatase is an enzyme that, in humans, is encoded by the GALNS gene. This gene encodes N- ... N-acetylgalactosamine-6-sulfate sulfatase exonic point mutations in classical Morquio and mild cases". J. Clin. Invest. 90 (3 ... Masue M, Sukegawa K, Orii T, Hashimoto T (1992). "N-acetylgalactosamine-6-sulfate sulfatase in human placenta: purification and ... Jan 1992). "Morquio disease: isolation, characterization and expression of full-length cDNA for human N-acetylgalactosamine-6- ...
N-Acetylgalactosamine Uridine Merck Index, 11th Edition, 4240. Apte, U. (2014), "Galactosamine", Encyclopedia of Toxicology, ...
This gene product mainly transfers sulfate to N-acetylgalactosamine. The regulated expression of each member of this gene ...
Baig, S.; Wilcock, G.; Love, S. (2005). "Loss of perineuronal net N-acetylgalactosamine in Alzheimer's disease". Acta ...
"UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter [Homo sapiens - Protein - NCBI]". www.ncbi.nlm.nih.gov. Retrieved ...
UDP-N-acetylgalactosamine: (N-acetylneuraminyl)-galactosylglucosyl ceramide N-acetylgalactosaminyltransferase in rat brain". ... Hashimoto Y, Sekine M, Iwasaki K, Suzuki A (December 1993). "Purification and characterization of UDP-N-acetylgalactosamine GM3 ... UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase, UDP-N-acetyl-D- ... UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine- ...
Aldurazyme by BioMarin Pharmaceutical and Genzyme N-acetylgalactosamine-4-sulfatase (rhASB; galsulfase): Naglazyme by BioMarin ...
"Molecular cloning and characterization of a dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase". The Journal of ... "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using ...
Ohtake S, Ito Y, Fukuta M, Habuchi O (Nov 2001). "Human N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase cDNA is related to ... It belongs to the N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase enzyme class. GRCh38: Ensembl release 89: ... "Difference between N-acetylgalactosamine 4-sulfate 6-O-sulfotransferases from human serum and squid cartilage in specificity ... "A unique nonreducing terminal modification of chondroitin sulfate by N-acetylgalactosamine 4-sulfate 6-o-sulfotransferase". J. ...
GSTs catalyze sulfation at the 6-hydroxyl group of galactose, N-acetylgalactosamine, or N-acetylglucosamine. Like heparan ... There are two major families of carbohydrate sulfotransferases: heparan sulfotransferases and galactose/N-acetylgalactosamine/N ... which transfer sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. ... "Molecular cloning and characterization of a dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase". J. Biol. Chem. 276 ( ...
... (EC 2.8.2.35, dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase, dermatan-4- ... "Molecular cloning and characterization of a dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase". The Journal of ... "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using ... sulfotransferase-1, dermatan-4-sulfotransferase 1, D4ST-1, dermatan N-acetylgalactosamine 4-O-sulfotransferase, CHST14 protein ...
... (N-acetylgalactosamine-4-sulfatase, chondroitinsulfatase, chondroitinase, acetylgalactosamine 4-sulfatase, N- ... Galsulfase (N-acetylgalactosamine-4-sulfatase, recombinant human) was granted orphan drug designation by both the European ... N-acetylgalactosamine-4-sulfatase): potential role as a biomarker in prostate cancer". Prostate Cancer and Prostatic Diseases. ... This disease is caused by the lack of an enzyme called N-acetylgalactosamine 4-sulfatase, which is needed to break down ...
The sugars are usually a combination of N-acetylgalactosamine, D-glucose or D-galactose. One characteristic of globosides is ...
Taniguchi N, Makita A (1984). "Purification and characterization of UDP-N-acetylgalactosamine: globotriaosylceramide beta-3-N- ... Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase". ... Identification of four inactivating mutations in the UDP-N-acetylgalactosamine: globotriaosylceramide 3-beta-N- ... N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding ...
Taniguchi N, Makita A (1984). "Purification and characterization of UDP-N-acetylgalactosamine: globotriaosylceramide beta-3-N- ... Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase". ...
... is part of the C-type lectin superfamily and binds to N-Acetylgalactosamine (GalNAc). It is mainly expressed on myeloid ... CLEC10A binds most strongly to N-Acetylgalactosamine (GalNAc), preferring α-GalNAc over β-GalNAc, unmodified galactose is bound ... October 2019). "The C-type lectin receptor MGL senses N-acetylgalactosamine on the unique Staphylococcus aureus ST395 wall ...
Warren, G.; Tooze, J.; Tooze, S. A. (1988-05-01). "Site of addition of N-acetyl-galactosamine to the E1 glycoprotein of mouse ...
The first sugar is always N-acetyl-galactosamine (GalNAc), followed by other galactoses and sialic acid. In HSP and IgAN, these ...