Three prime untranslated region
... untranslated region, 3′ untranslated region and poly(A) tail. Regulatory regions within the 3′-untranslated region can ... untranslated region also has regulatory functions. Protein factors can either aid or disrupt folding of the region into various ... Five prime untranslated region UTRdb UTRome Barrett, Lucy W.; Fletcher, Sue; Wilton, Steve D. (27 April 2012). "Regulation of ... The 3′-untranslated region plays a crucial role in gene expression by influencing the localization, stability, export, and ...
OSER1
... untranslated region 252 bp long. 3' untranslated region 1,129 bp long. 10 splice isoforms that encode good proteins, altogether ... In this same region of the promoter, there is also a TATA-binding factor sequence, which helps in the positioning of RNA ... The protein is highly conserved in the DUF776 region amongst vertebrates, and also at the C-terminus in eukaryotes. Using tools ... 294 (5): 1351-62. doi:10.1006/jmbi.1999.3310. PMID 10600390. Human OSER1 genome location and OSER1 gene details page in the ...
Glossary of genetics (0-L)
... including untranslated regions of mature mRNAs as well as coding regions. exon Any part of a gene that encodes a part of the ... Contents 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z See also References External links 3' untranslated region (3'- ... five-prime untranslated region See 5' untranslated region. fixation The process by which a single allele for a particular gene ... untranslated region, but may also be found in other positions. interphase All stages of the cell cycle excluding cell division ...
Untranslated region
Regulatory Activity Coding region Five prime untranslated region History of RNA biology MiRNA Three prime untranslated region ... Although they are called untranslated regions, and do not form the protein-coding region of the gene, uORFs located within the ... The untranslated regions of mRNA became a subject of study as early as the late 1970s, after the first mRNA molecule was fully ... The untranslated region is seen in prokaryotes and eukaryotes, although the length and composition may vary. In prokaryotes, ...
TMEM212
... untranslated region is 35 base pairs long. The 3' untranslated region is 1221 base pairs in length and is located from base 661 ... However, 2 of the transmembrane regions contain a polar, charged amino acid. The protein is 194 amino acids long and has a ... Most of the conserved areas fell where transmembrane regions are localized. TMEM212 is evolving moderately quickly compared to ... specifically in the transmembrane regions. The alpha helices were conserved in orthologs from mammals to reptiles. Additionally ...
Flavivirus 5' UTR
UTR are untranslated regions in the genome of viruses in the genus Flavivirus. The Flavivirus positive-oriented, single- ... Untranslated Regions of the Flaviviral Genome". Viruses. 9 (6): 137. doi:10.3390/v9060137. ISSN 1999-4915. PMC 5490814. PMID ... After recruitment of NS5, the two loop regions of S3 (TL) and SSD (SSL) are considered to interact with NS5 to promote ... The capsid-coding hairpin region (cHP) actually lies in the ORF of the viral genome and is followed by the 5'CS (conserved ...
Flavivirus 3' UTR
... are untranslated regions in the genome of viruses in the genus Flavivirus. The Flavivirus positive-oriented, ... Untranslated Region of the Dengue Virus Type 2 RNA That Modulate Translation and Replication". Journal of Biological Chemistry ... Untranslated Regions of the Flaviviral Genome". Viruses. 9 (6): 137. doi:10.3390/v9060137. ISSN 1999-4915. PMC 5490814. PMID ... untranslated region". Virus Research. 206: 53-61. doi:10.1016/j.virusres.2015.01.026. PMID 25660582. Chapman, E. G.; Costantino ...
C9orf135
Untranslated regions (UTR) contain hairpin loops. The 3' UTR comprises 123 nucleotides and the 5' UTR comprises 18 nucleotides ... 95 (5): 1595-600. doi:10.1016/j.fertnstert.2010.12.052. PMC 3062633. PMID 21256485. Chung SJ, Armasu SM, Biernacka JM, Anderson ... Secondary structure of c9orf135 5' UTR loop structure of c9orf135 of mRNA 3' UTR loop structure of c9orf135 mRNA It is likely ...
Osteopontin
... untranslated region (5' UTR). Exons 2, 3, 4, 5, 6, and 7 code for 17, 13, 27, 14, 108 and 134 amino acids, respectively. All ... The gene has 7 exons, spans 5 kilobases in length and in humans it is located on the long arm of chromosome 4 region 22 ( ... 19 (5-6): 333-345. doi:10.1016/j.cytogfr.2008.08.001. PMID 18952487. Rangaswami H, Bulbule A, Kundu GC (February 2006). " ... 5 (2): e9330. Bibcode:2010PLoSO...5.9330A. doi:10.1371/journal.pone.0009330. PMC 2824833. PMID 20174473. Hunter GK, O'Young J, ...
Heat shock protein 70 (Hsp70) internal ribosome entry site (IRES)
... untranslated region of human hsp70 mRNA". The Journal of Biological Chemistry. 278 (25): 22350-22356. doi:10.1074/jbc. ... It has been shown that the 216 nucleotide long 5' UTR contains internal ribosome entry site activity. Rubtsova MP, Sizova DV, ... Dmitriev SE, Ivanov DS, Prassolov VS, Shatsky IN (June 2003). "Distinctive properties of the 5'- ...
Collagen, type VI, alpha 2
... untranslated region generated by an alternate exon". J. Biol. Chem. 267 (9): 6188-96. doi:10.1016/S0021-9258(18)42680-4. PMID ... 1992). "The exon organization of the triple-helical coding regions of the human alpha 1(VI) and alpha 2(VI) collagen genes is ... 14 (1): 113-5. doi:10.1038/ng0996-113. PMID 8782832. S2CID 26173341. Tillet E, Ruggiero F, Nishiyama A, Stallcup WB (1997). " ...
KLF9
... untranslated region". J. Biol. Chem. 269 (32): 20668-73. doi:10.1016/S0021-9258(17)32045-8. PMID 8051167. Imataka H, Mizuno A, ... Regions around 10 kb upstream and 1 kb downstream of Klf9 transcription start site contain conserved antioxidant response ... a GC box sequence in the promoter region of the rat P-4501A1 gene". EMBO J. 11 (10): 3663-71. doi:10.1002/j.1460-2075.1992. ... 19 (5): 499-503. doi:10.1007/BF01233255. PMID 8291025. S2CID 45624023. Zhang XL, Zhang D, Michel FJ, Blum JL, Simmen FA, Simmen ...
NuoG RNA motif
RNA thermometer
... untranslated region (UTR) of messenger RNA encoding heat shock proteins-though it has been suggested this fact may be due, in ... untranslated region elements essential for preferential heat shock translation". J Biol Chem. 279 (48): 49919-49930. doi: ... Some RNA thermometers are significantly more complex than a single hairpin, as in the case of a region found in CspA mRNA which ... This structural transition can then expose or occlude important regions of RNA such as a ribosome binding site, which then ...
CMP kinase
... untranslated region". Life Sciences. 69 (20): 2361-70. doi:10.1016/S0024-3205(01)01322-4. PMID 11681623. Liou JY, Dutschman GE ... "Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library". Gene. 200 (1-2): 149-56. doi: ... "Characterization of human UMP-CMP kinase enzymatic activity and 5′ ...
Overlapping gene
... untranslated regions (UTRs) along with introns. Overprinting refers to a type of overlap in which all or part of the sequence ... However, these overlap regions are known to be less important for replication compared to the overlap regions that were highly ... The spacer domain of the polymerase and the pre-S1 region of a surface protein of HBV, for example, had a percentage of ... In tombusviruses, the proteins p19 and p22 are encoded by overlapping genes that form a 549 nt coding region, and p19 is shown ...
Hsp90 cis-regulatory element
... untranslated region elements essential for preferential heat shock translation". The Journal of Biological Chemistry. 279 (48 ... The Hsp90 cis regulatory element is an RNA element (RNA thermometer) found in the 5' UTR of the Drosophila hsp90 mRNA. It is ...
UCK2
... untranslated region". Life Sciences. 69 (20): 2361-70. doi:10.1016/S0024-3205(01)01322-4. PMID 11681623. Liou JY, Dutschman GE ... 12 (5): 751-64. doi:10.1016/j.str.2004.02.038. PMID 15130468. Appleby TC, Larson G, Cheney IW, Walker H, Wu JZ, Zhong W, Hong Z ... 12 (5): 751-64. doi:10.1016/j.str.2004.02.038. PMID 15130468. Murata D, Endo Y, Obata T, Sakamoto K, Syouji Y, Kadohira M, ... 59 (5): 1181-6. doi:10.1124/mol.59.5.1181. PMID 11306702. S2CID 9290273. Koizumi K, Shimamoto Y, Azuma A, Wataya Y, Matsuda A, ...
Complement receptor 1
The transmembrane region is encoded by 2 exons and the cytoplasmic domain and the 3'-untranslated regions are coded for by two ... untranslated region are contained in one exon. The large extracellular domain of CR1, which has 25 potential N-glycosylation ... This gene is a member of the regulators of complement activation (RCA) family and is located in the 'cluster RCA' region of ... The promoter region lacks a distinct TATA box sequence. The gene is expressed principally on erythrocytes, monocytes, ...
FourU thermometer
... untranslated region of the gene for heat shock protein Salmonella agsA, they repress translation of this protein by base- ... untranslated region elements essential for preferential heat shock translation". The Journal of Biological Chemistry. 279 (48 ... 110 (5): 551-561. doi:10.1016/S0092-8674(02)00905-4. PMID 12230973. Bukau B (August 1993). "Regulation of the Escherichia coli ... 278 (5): 555-564. doi:10.1007/s00438-007-0272-7. PMID 17647020. S2CID 24747327. Ahmed R, Duncan RF (November 2004). " ...
Vasa gene
Untranslated Region to the germ line cells. Translation can be inhibited by cis regulatory elements in the transcript's 5' and ... untranslated regions of mRNAs in human diseases". Biology of the Cell. 101 (5): 251-62. doi:10.1042/BC20080104. PMID 19275763. ... After the duplication event, the N-terminal region acquired Zn-knuckle domains which are now conserved in invertebrates. ... and arginine methylation in a conserved region of mice, Xenopus and Drosophila Vasa genes. One of main function of Vasa protein ...
Tahyna orthobunyavirus
... untranslated regions (UTR) are complementary and highly conserved. The S segment encodes two proteins: the nucleoprotein (N) ... despite the fact that the viruses were collected from temporally distinct regions spanning a 10 to 26 year period. This level ... 29 (5): 1051-1077. doi:10.1016/j.femsre.2005.04.012. ISSN 1574-6976. PMC 7110368. PMID 16024128. Juřicová, Z.; Hubálek, Z.; ...
Five prime untranslated region
Three prime untranslated region UORF Iron-responsive element-binding protein Iron response element Trans-splicing UTRdb Penalva ... Mignone, Flavio; Gissi, Carmela; Liuni, Sabino; Pesole, Graziano (2002). "Untranslated regions of mRNAs". Genome Biology. 3 (3 ... untranslated region (also known as 5′ UTR, leader sequence, transcript leader, or leader RNA) is the region of a messenger RNA ... While called untranslated, the 5′ UTR or a portion of it is sometimes translated into a protein product. This product can then ...
CLCN5
... untranslated region (5'UTR) of CLCN5 is complex and not entirely clarified. Two strong and one weak promoters were predicted to ... It extends over about 170 Kb of genomic DNA, has a coding region of 2,238 bp and consists of 17 exons including 11 coding exons ... Tosetto E, Casarin A, Salviati L, Familiari A, Lieske JC, Anglani F (July 2014). "Complexity of the 5'UTR region of the CLCN5 ... "ATP induces conformational changes in the carboxyl-terminal region of ClC-5". The Journal of Biological Chemistry. 286 (8): ...
INAVA
... untranslated region is shown. Isoform 1, diagramed below, contains a DUF3338 domain, two low complexity regions and a proline ... The factors that are predicted to bind to the promoter region of isoform 2 differ, and twelve of the top twenty predicted ... A total of 556 single nucleotide polymorphisms (SNPs) have been identified in the gene region of INAVA, 96 of which are ... A diagram of the predicted promoter region, with highlighted transcription factor binding sites, is shown to the right. ...
CGB1
... untranslated region. This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit, however ... 267 (5): 3179-84. doi:10.1016/S0021-9258(19)50712-8. PMID 1371113. Policastro PF, Daniels-McQueen S, Carle G, Boime I (1986). " ... The CGB genes are primarily distinguished by differences in the 5' ...
RNF128
... untranslated region that are highly conserved. The RNF128 protein contains a signal peptide. This peptide is cleaved at the RGA ... The ring-H2 region is the most highly conserved region in these alignments and is conserved in mammals, birds, amphibians, ... transmembrane region, and the ring-H2 region. The signal peptide is not conserved in any of the more distant homologs, but is ... untranslated region on RNF128. There are also several areas of the 5' ...
Pyrobaculum aerophilum
... untranslated regions in its mRNAs. This implies that it does not employ the Shine-Delgarno sequence to initiate protein ... 5 (3): 402-408. doi:10.1111/j.1432-1033.1968.tb00383.x. ISSN 0014-2956. PMID 4300601. S2CID 40457534. Solomons, J. T. Graham; ... Whole genome analysis demonstrated that it lacks 5' ...
Iron response element
... untranslated regions) of various mRNAs whose products are involved in iron metabolism. For example, the mRNA of ferritin (an ... untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy". The Journal of ... untranslated region". Proceedings of the National Academy of Sciences of the United States of America. 84 (23): 8478-8482. doi: ... untranslated region". The Journal of Biological Chemistry. 270 (51): 30781-30786. doi:10.1074/jbc.270.51.30781. PMID 8530520. N ...
Negevirus
There are untranslated regions at the 5' and 3' ends of the genome. These vary with the 5' end being between 72 and 730 and the ... There are three open reading frames (ORFs). The largest open reading frame lies toward the 5' end of the genome and encodes a ... J Virol 87(5):2475-2488 (Taxa that may be invalid, Articles with short description, Short description matches Wikidata, ...