Von Willebrand factor - Wikipedia
Includes: Type 1 von Willebrand Disease, Type 2A von Willebrand Disease, Type 2B von Willebrand Disease, Type 2M von Willebrand ... Von Willebrand Factors primary function is binding to other proteins, in particular factor VIII, and it is important in ... June 2011). "Plasma von Willebrand factor levels are an independent risk factor for adverse events including mortality and ... Although von Willebrand did not identify the definite cause, he distinguished von Willebrand disease (vWD) from hemophilia and ...
FDA OKs First Recombinant von Willebrand Factor (Vonvendi)
The approval of Vonvendi provided an additional therapeutic option for the treatment of bleeding episodes in patients with von ... von Willebrand disease is usually treated with desmopressin or with von Willebrand factor/factor VIII concentrates derived from ... Even though von Willebrand disease is relatively common, at least among bleeding disorders, the FDA granted von Willebrand ... The US Food and Drug Administration (FDA) has approved the first recombinant von Willebrand factor, to be used for the on- ...
Browsing by Subject "von Willebrand Factor"
RCSB PDB - 1AUQ: A1 DOMAIN OF VON WILLEBRAND FACTOR
von Willebrand Factor (vWF) is a multimeric protein that mediates platelet adhesion to exposed subendothelium at sites of ... von Willebrand Factor (vWF) is a multimeric protein that mediates platelet adhesion to exposed subendothelium at sites of ... Crystal structure of the von Willebrand Factor A1 domain and implications for the binding of platelet glycoprotein Ib.. Emsley ... A1 DOMAIN OF VON WILLEBRAND FACTOR. *PDB DOI: https://doi.org/10.2210/pdb1AUQ/pdb ...
von Willebrand Factor Multimers: Reference Range, Interpretation, Collection and Panels
... multimer analysis is primarily a qualitative tests to identify variants of type II von Willebrand disease (vWD); therefore, ... Why is von Willebrand factor (vWF) multimer analysis performed?. How are specimens collected for von Willebrand factor (vWF) ... encoded search term (von Willebrand Factor Multimers) and von Willebrand Factor Multimers What to Read Next on Medscape ... The von Willebrand factor (vWF) multimer analysis is primarily a qualitative test to identify variants of type II von ...
Blood Test: von Willebrand Factor (vWF) Antigen (for Parents) - Nemours KidsHealth
Doctors order the vWF antigen test to help diagnose or monitor the treatment of von Willebrand disease. ... A von Willebrand factor (vWF) antigen test measures the amount of a clotting factor called von Willebrand factor. ... Von Willebrand factor is involved in a few stages of blood clotting. An abnormal gene can make some kids not have enough vWF, ... factor IX activity test. Factor VIII and vWF circulate in the body bound to one another. So a decreased amount of factor VIII ...
VWA5A von Willebrand factor A domain containing 5A [Homo sapiens (human)] - Gene - NCBI
VWA5A von Willebrand factor A domain containing 5A [Homo sapiens] VWA5A von Willebrand factor A domain containing 5A [Homo ... vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor ( ... von Willebrand factor A domain containing 5Aprovided by HGNC. Primary source. HGNC:HGNC:6658 See related. Ensembl: ... von Willebrand factor A domain-containing protein 5A. Names. breast cancer suppressor candidate 1. loss of heterozygosity 11 ...
MedlinePlus - Search Results for: VON WILLEBRAND FACTOR HUMAN
coagulation factor VIII is activated and separates from von Willebrand factor. The active protein (sometimes written as ... thrombospondin type 1 motif, 13 ADAMTS-13 ATS13_HUMAN C9orf8 von Willebrand factor-cleaving protease vWF-cleaving protease vWF- ... an inactive form, bound to another molecule called von Willebrand factor, until an injury that damages blood vessels occurs ... Rare Clotting Factor Deficiencies (World Federation of Hemophilia) Bleeding Disorders/Specifics ... Bleeding Disorders ... ...
Browsing by Subject "von Willebrand Factor"
Vwf MGI Mouse Gene Detail - MGI:98941 - Von Willebrand factor
von Willebrands disease 3 DOID:0111054. ICD10CM:D68.03. MESH:D056729. NCI:C85213. OMIM:277480. ORDO:166096. UMLS_CUI:C1264041 ... Human Disease Modeled: von Willebrands disease 2. Allelic Composition. Genetic Background. Reference. Phenotypes. ... Human Disease Modeled: von Willebrands disease. Allelic Composition. Genetic Background. Reference. Phenotypes. ... J:338621 Roullet S, et al., Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine ...
Elevated levels of von Willebrand Factor in cirrhosis support platelet adhesion despite reduced functional capacity
Extracellular Vimentin/VWF (von Willebrand Factor) Interaction Contributes to VWF String Formation and Stroke Pathology
... von Willebrand factor) strings mediate spontaneous platelet adhesion in the vascular lumen, which may lead to microthrombi ... Extracellular Vimentin/VWF (von Willebrand Factor) Interaction Contributes to VWF String Formation and Stroke Pathology Stroke ... Background and Purpose- VWF (von Willebrand factor) strings mediate spontaneous platelet adhesion in the vascular lumen, which ...
Recombinate von Willebrand Factor
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Von Willebrand Factor Multimers during Transcatheter Aortic-Valve Replacement - Heart
Von Willebrand Factor Multimers during Transcatheter Aortic-Valve Replacement. Posted on September 20, 2016. by ... Patients with stenotic or regurgitant aortic valve disease appear to cleave multimers of Von Willebrand factor (HMW-multimer), ... Von Willebrand Factor Multimers during Transcatheter Aortic-Valve Replacement. N Engl J Med. 2016;375:335-344. ...
Abnormal degradation of von Willebrand factor main subunit in pulmonary hypertension | European Respiratory Society
Abnormal degradation of von Willebrand factor main subunit in pulmonary hypertension. AA Lopes, NY Maeda ... Abnormal degradation of von Willebrand factor main subunit in pulmonary hypertension Message Subject (Your Name) has sent you a ... We wished to investigate whether the abnormalities in multimeric structure and biological function of von Willebrand factor ( ...
Inflammation, von Willebrand factor, and ADAMTS13 - PubMed
Increasing evidence indicates that inflammation can cause thrombosis by a von Willebrand factor (VWF)-mediated mechanism that ... Endothelial Cell-Derived von Willebrand Factor Is the Major Determinant That Mediates von Willebrand Factor-Dependent Acute ... Inflammation, von Willebrand factor, and ADAMTS13 Junmei Chen 1 , Dominic W Chung 1 2 ... Inflammation, von Willebrand factor, and ADAMTS13 Junmei Chen et al. Blood. 2018. . ...
Pharmaceuticals | Free Full-Text | Dose-Dependent Von Willebrand Factor Inhibition by Aptamer BB-031 Correlates with...
Von Willebrand Factor (VWF) plays a critical role in thrombus formation, stabilization, and propagation. Previous studies have ... Dose-Dependent Von Willebrand Factor Inhibition by Aptamer BB-031 Correlates with Thrombolysis in a Microfluidic Model of ... Dose-Dependent Von Willebrand Factor Inhibition by Aptamer BB-031 Correlates with Thrombolysis in a Microfluidic Model of ... "Dose-Dependent Von Willebrand Factor Inhibition by Aptamer BB-031 Correlates with Thrombolysis in a Microfluidic Model of ...
Von Willebrand Factor - Drugs and Lactation Database (LactMed) - NCBI Bookshelf
Until more data become available, von Willebrand factor should be used with caution during breastfeeding, especially while ... No information is available on the clinical use of von Willebrand factor during breastfeeding. Because it is a large protein ... Von Willebrand Factor - Drugs and Lactation Database (LactMed). Von Willebrand Factor - Drugs and Lactation Database (LactMed) ... Platelet adhesion to collagen in subtypes of type I von Willebrands disease is dependent on platelet von Willebrand factor.[ ...
von Willebrand Factor Multimers: Reference Range, Interpretation, Collection and Panels
... multimer analysis is primarily a qualitative tests to identify variants of type II von Willebrand disease (vWD); therefore, ... Why is von Willebrand factor (vWF) multimer analysis performed?. How are specimens collected for von Willebrand factor (vWF) ... encoded search term (von Willebrand Factor Multimers) and von Willebrand Factor Multimers What to Read Next on Medscape ... The von Willebrand factor (vWF) multimer analysis is primarily a qualitative test to identify variants of type II von ...
Reactome | factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor...
factor VIII + von Willebrand factor multimer -, factor VIII:von Willibrand factor multimer Stable Identifier ... factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor multimer (Bos taurus) ... factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor multimer (Homo sapiens) ...
Monitoring of von Willebrand Factor Inhibitors in Patients with Type 3 von Willebrand Disease Using a Quantitative Assay
Von Willebrand Disease Von Willebrand Disease, Type 3 Von Willebrand Diseases Von Willebrand Factor Factor VIII Von Willebrand ... Monitoring of von Willebrand Factor Inhibitors in Patients with Type 3 von Willebrand Disease Using a Quantitative Assay. ... Antibodies inhibiting von Willebrand factor (VWF) develop in a subset of patients with Type 3 von Willebrand disease (VWD3) and ... Monitoring of von Willebrand Factor Inhibitors in Patients with Type 3 von Willebrand Disease Using a Quantitative Assay ...
Determination of Two Rapid Von Willebrand Factor (VWF) Activ | 25511
Von Willebrand disease: MedlinePlus Genetics
Von Willebrand disease is a bleeding disorder that slows the blood clotting process, causing prolonged bleeding after an injury ... Variants that severely reduce or eliminate von Willebrand factor cause type 3 von Willebrand disease. People with type 3 von ... von Willebrand factor forms clots too easily. The clots are removed from the body, so there is not enough von Willebrand factor ... Variants in the VWF gene that reduce the amount of von Willebrand factor cause type 1 von Willebrand disease. In type 1C, the ...
Interdependence investigation of dynamic between the von Willebrand factor and erythrocyte and leukocyte intoxication indices...
peritonitis, experimental research, von Willebrand factor, erythrocyte intoxication index (EII), leukocyte intoxication index ( ... peritonitis, experimental research, von Willebrand factor, erythrocyte intoxication index (EII), leukocyte intoxication index ( ... Interdependence investigation of dynamic between the von Willebrand factor and erythrocyte and leukocyte intoxication indices ... Interdependence investigation of dynamic between the von Willebrand factor and erythrocyte and leukocyte intoxication indices ...
von Willebrand Factor Multimers: Reference Range, Interpretation, Collection and Panels
... multimer analysis is primarily a qualitative tests to identify variants of type II von Willebrand disease (vWD); therefore, ... Why is von Willebrand factor (vWF) multimer analysis performed?. How are specimens collected for von Willebrand factor (vWF) ... encoded search term (von Willebrand Factor Multimers) and von Willebrand Factor Multimers What to Read Next on Medscape ... The von Willebrand factor (vWF) multimer analysis is primarily a qualitative test to identify variants of type II von ...
What is von Willebrand Disease? | CDC
One of these proteins is called von Willebrand factor (VWF). People with VWD either have a low level of VWF in their blood or ... Von Willebrand disease (VWD) is a blood disorder in which the blood does not clot properly. Blood contains many proteins that ... Factor Replacement Therapy. Recombinant VWF (such as Vonvendi®) and medicines rich in VWF and factor VIII (for example, Humate ... This causes the body to remove the Factor VIII (8) protein.. Type 3. This is the most severe form of VWD, in which a person has ...
Von Willebrand factor - wikidoc
Includes: Type 1 von Willebrand Disease, Type 2A von Willebrand Disease, Type 2B von Willebrand Disease, Type 2M von Willebrand ... 1ijk: The von Willebrand Factor mutant (I546V) A1 domain-botrocetin Complex. 1ijk: The von Willebrand Factor mutant (I546V) A1 ... 1u0n: The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex. 1u0n: The ternary von Willebrand Factor A1- ... See also: Erik Adolf von Willebrand § Von Willebrand disease. VWF is named after Erik Adolf von Willebrand, a Finnish physician ...
Von Willebrand disease: MedlinePlus Genetics
Von Willebrand disease is a bleeding disorder that slows the blood clotting process, causing prolonged bleeding after an injury ... Variants that severely reduce or eliminate von Willebrand factor cause type 3 von Willebrand disease. People with type 3 von ... von Willebrand factor forms clots too easily. The clots are removed from the body, so there is not enough von Willebrand factor ... Variants in the VWF gene that reduce the amount of von Willebrand factor cause type 1 von Willebrand disease. In type 1C, the ...
New Strategies for Laboratory Testing of vonWillebrand Factor - Siemens Healthineers Indonesia
Understand what is current biological function of von Willebrand factor and how that understanding affects testing strategies ... There have been recent advances in von Willebrand disease (vWD) testing as well as recent updates in the diagnosis and ... von Willebrand disease testing, therapeutic apheresis outcomes, and pediatric reference intervals. ...