*  Integrin traffic | Journal of Cell Science
Several viruses also use integrins for their internalization (see Table 1). Echovirus1 and rotavirus enter cells via α2β1- ... O'Donnell, V., LaRocco, M., Duque, H. and Baxt, B. (2005). Analysis of foot-and-mouth disease virus internalization events in ... However, internalization of α5β1 integrin is not impaired by these mutations to the β1 tail despite the fact that it is ... Peng, J. M., Liang, S. M. and Liang, C. M. (2004). VP1 of foot-and-mouth disease virus induces apoptosis via the Akt signaling ...
  http://jcs.biologists.org/content/119/18/3723
*  A cell-based dual-reporter system for monitoring HCV in | Open-i
The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular carcinomas ... The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular carcinomas ... Bottom Line: The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular ... Bottom Line: The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4352851_srep08865-f1&req=4
*  Viruses | Free Full-Text | CD81-Receptor Associations - Impact for Hepatitis C Virus Entry and Antiviral Therapies | HTML
CD81 also plays a crucial role in pathogen entry into host cells, including hepatitis C virus (HCV) entry into hepatocytes. HCV ... Ceramide enrichment of the plasma membrane induces CD81 internalization and inhibits hepatitis C virus entry. Cell. Microbiol. ... RNA viruses including HCV, influenza virus and retroviruses exhibit profound genetic diversity resulting from error prone ... Noteworthy, integrins are used as host entry receptors by many viruses [36]. This suggests that these viruses may enter host ...
  http://www.mdpi.com/1999-4915/6/2/875/htm
*  WWP2 - Wikipedia
Galinier R, Gout E, Lortat-Jacob H, Wood J, Chroboczek J (2003). "Adenovirus protein involved in virus internalization recruits ... "Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine ...
  https://en.wikipedia.org/wiki/WWP2
*  WWP1 - Wikipedia
Galinier R, Gout E, Lortat-Jacob H, Wood J, Chroboczek J (2003). "Adenovirus protein involved in virus internalization recruits ...
  https://en.wikipedia.org/wiki/WWP1
*  Lassa virus - Wikipedia
It was reported that virus internalization is limited upon cholesterol depletion. The receptor used for cell entry is alpha- ... Lassa virus is an emerging virus and a select agent, requiring Biosafety Level 4-equivalent containment. It is endemic in West ... By 1972, the multimammate rat was found to be the main reservoir of the virus in West Africa, able to shed virus in its urine ... Samples from Pinneo were sent to Yale University in New Haven where a new virus, that would later be known as Lassa virus, was ...
  https://en.wikipedia.org/wiki/Lassa_virus
*  Adenovirus receptors and their implications in gene delivery
Virus Res. 2004;105:127-136. [PubMed]. *Bangari DS, Mittal SK. Porcine adenovirus serotype 3 internalization is independent of ... Besides internalization, the integrin αvβ5 plays a major role in membrane permeabilization and virus escape into the cytosol ( ... Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell. 1993;73:309-319. ... Virus taxonomy: Eighth Report of the International Committee on the Taxonomy of Viruses. Elsevier Academic Press; San Diego: ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2903974/
*  The rate-shifting pattern at site 414 of gp120, display | Open-i
One may speculate that these subtypes infect patients where a certain allele of CCR5 is more common, and the virus has adapted ... One may speculate that these subtypes infect patients where a certain allele of CCR5 is more common, and the virus has adapted ... A hallmark of the human immunodeficiency virus 1 (HIV-1) is its rapid rate of evolution within and among its various subtypes. ... For instance, the CCR5 Δ32 mutation is known to confer reduced susceptibility to the virus in Europe and western Asia [45], and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2566816_pcbi.1000214.g004&req=4
*  IFITM-mediated restriction of virus-endosome fusion in | Open-i
IFITM-mediated restriction of virus-endosome fusion in different cell types.(A) IFITM3-mediated inhibition of viral fusion with ... Here, we examined IAV restriction by IFITM3 protein using direct virus-cell fusion assay and single virus imaging in live cells ... Here, we examined IAV restriction by IFITM3 protein using direct virus-cell fusion assay and single virus imaging in live cells ... IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3974867_ppat.1004048.g001&req=4
*  Real-time PCR analysis of expression profiles of BmNPV | Open-i
A virus overlay assay was used to detect B. mori proteins that specifically bind to BmNPV particles. Twelve proteins were ... A virus overlay assay was used to detect B. mori proteins that specifically bind to BmNPV particles. Twelve proteins were ... vacuolar ATP synthase catalytic subunit A and subunit B may be implicated in the process of the membrane fusion of virus and ... vacuolar ATP synthase catalytic subunit A and subunit B may be implicated in the process of the membrane fusion of virus and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4264868_pone.0115032.g004&req=4
*  Pak1 is required for ASFV entry in Vero cells.A) ASFV a | Open-i
African swine fever (ASF) is caused by a large and highly pathogenic DNA virus, African swine fever virus (ASFV), which ... We have also found that internalization of the virions depends on actin reorganization, activity of Na(+)/H(+) exchangers, and ... African swine fever (ASF) is caused by a large and highly pathogenic DNA virus, African swine fever virus (ASFV), which ... African swine fever virus uses macropinocytosis to enter host cells. Sánchez EG, Quintas A, Pérez-Núñez D, Nogal M, Barroso S, ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3375293_ppat.1002754.g007&req=4
*  "Arenaviruses: mechanisms of antibody-mediated neutralization and an al" by Rachel Bottjen Brouillette
Junín virus (JUNV), and Lassa virus (LASV), are causative agents of Bolivian hemorrhagic fever, Argentine hemorrhagic fever, ... all three viruses are considered category A priority pathogens by the CDC. Arenavirus glycoproteins (GPCs) are considered class ... The three arenaviruses studied in this thesis, Machupo virus (MACV), ... This provides evidence that mechanism of virus internalization is viral glycoprotein-dependent and cell surface receptor- ...
  http://ir.uiowa.edu/etd/5429/
*  Surface plasmon resonance showed papuamide A did not in | Open-i
HIV pseudotype viruses expressing envelope glycoproteins from vesicular stomatitis virus or amphotropic murine leukemia virus ... HIV pseudotype viruses expressing envelope glycoproteins from vesicular stomatitis virus or amphotropic murine leukemia virus ... We show here that papuamide A acts as an entry inhibitor, preventing human immunodeficiency virus infection of host cells and ... We show here that papuamide A acts as an entry inhibitor, preventing human immunodeficiency virus infection of host cells and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2630844_md-06-00528f3&req=4
*  Plus it
... which allows virus attachment but not fusion and internalization) to 37°C (which allows virus fusion and internalization; ... "bound virus") and internalization into ("internalized virus") the cell. Viral DNA was quantified by qRT-PCR and results ... to allow virus internalization) before being harvested by trypsinization for DNA quantification by qRT-PCR. ... and hCMV DNA was expressed as the percentage of virus bound (the "attachment" step) or internalized (the "internalization" step ...
  http://www.jneurosci.org/content/37/29/6877
*  RG 6024 - AdisInsight
Mechanism of Action Virus internalisation inhibitors * Orphan Drug Status Orphan designation is assigned by a regulatory body ... Phase I Influenza B virus infections Most Recent Events * 01 Jan 2016 Genentech completes a phase I trial in Influenza-B virus ... 22 Oct 2015 Phase-I clinical trials in Influenza-B virus infections (In volunteers) in Canada (IV) (NCT02528903) ... 24 Aug 2015 Genentech plans a phase I trial for Influenza B virus infections in Canada (NCT02528903) ...
  http://adisinsight.springer.com/drugs/800043112?error=cookies_not_supported&code=c8bd8115-dff5-459c-b2a5-a61bbc065559
*  'influenza a virus' Protocols and Video...
Measuring Attachment and Internalization of Influenza A Virus in A549 Cells by Flow Cytometry', 'Co-immunoprecipitation of the ... Influenza A Virus Studies in a Mouse Model of Infection', 'Using Zebrafish Models of Human Influenza A Virus Infections to ... Influenza Virus Propagation in Embryonated Chicken Eggs', 'Expression and Purification of Virus-like Particles for Vaccination ... Mouse Mx1 Protein with the Influenza A Virus Nucleoprotein', 'Nasal Wipes for Influenza A Virus Detection and Isolation from ...
  https://www.jove.com/keyword/influenza+a+virus
*  Viruses | Free Full-Text | Endocytic Pathways Involved in Filovirus Entry: Advances, Implications and Future Directions | HTML
While it is generally agreed that filovirus entry into the host cytoplasm requires viral internalization into acidic endosomal ... Detailed knowledge of the host-virus interactions that accompany filovirus entry into cells is expected to identify ... Bundibugyo virus [BDBV], Ebola virus [EBOV], Sudan virus [SUDV]) and one marburgvirus (Marburg virus [MARV]) are associated ... Nemerow, G.R.; Cooper, N.R. Early events in the infection of human B lymphocytes by Epstein-Barr virus: The internalization ...
  http://mdpi.com/1999-4915/4/12/3647/htm
*  Characterization of hepatitis C Virus genotype 3a hypervariable region 1 in patients achieved rapid virological response to...
Hepatitis C virus roots a chronic liver disease. Currently approved treatment strategy includes administration of alpha ... and GAG's that are proposed to be involved in virus internalization [22] and receptor virus interaction [23] respectively ... Agnello V,Abel G,Elfahal M,Knight GB,Zhang QX,Hepatitis C virus and other flaviviridae viruses enter cells via low density ... Pretreatment serum hepatitis C virus RNA levels and hepatitis C virus genotype are the main and independent prognostic factors ...
  http://www.biomedsearch.com/nih/Characterization-Hepatitis-C-Virus-genotype/21605410.html
*  Anti-Rhinovirus Activity of Ethyl 4-(3-(2-(3-Methylisoxazol-5-Yl) Ethoxy) Propoxy) Benzoate (EMEB) | OMICS International
... the virus internalization into the cells, the viral uncoating, transcription and translation, and finally on viral ... by analysing its adhesion to the cell virus internalization into the cells, the viral uncoating, transcription and translation ... Viruses and cell lines. Rhinovirus HRV 14 and HRV 39. Isolated from throat washings of patients with respiratory illness [4-7 ... Neutral redi s added to the medium; cells not damaged by virus take up a greater amount of dye, which is read on a computerized ...
  https://www.omicsonline.org/open-access/antirhinovirus-activity-of-ethyl-4323methylisoxazol5yl-ethoxypropoxy-benzoate-emeb-2153-2435-1000469.php?aid=71077
*  HAVCR1 - Wikipedia
TIM-1 enhanced dengue virus infectivity by 500-fold, particularly increased virus internalization. TIM-1 directly interacted ... TIM-1 binds to Ebola virus glycoproteins (GP) and mediates Ebola virus cellular entry by increasing Ebola virus infectivity in ... that include viruses such as dengue and ebola. Interestingly entry of Lassa fever virus, influenza A virus, and SARS ... is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus- ...
  https://en.wikipedia.org/wiki/HAVCR1
*  Herpes Simplex Virus Glycoproteins H/L Bind to Cells Independently of αVβ3 Integrin and Inhibit Virus Entry, and Their...
... induction of signaling activities that target virus internalization, modification of the cellular cytoskeleton, etc. A similar ... Herpes simplex virus glycoprotein D mediates interference with herpes simplex virus infection. J. Virol. 63:819-827. [PMC free ... Herpes simplex virus glycoprotein B binds to cell surfaces independently of heparan sulfate and blocks virus entry. J. Virol. ... Herpes Simplex Virus Glycoproteins H/L Bind to Cells Independently of αVβ3 Integrin and Inhibit Virus Entry, and Their ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2849490/
*  Systemic Vesicular Stomatitis Virus Selectively Destroys Multifocal Glioma and Metastatic Carcinoma in Brain | Journal of...
9 C,D). These data suggest that VSV binding to the plasma membrane and virus internalization appear to be greater in glioma ... Detection of recombinant virus and tumor. To localize the virus, we used a green fluorescent reporter gene coupled to the VSV-G ... Viruses.. Ten days after tumor grafting, 100 μl of medium containing virus (107 plaque forming units (PFU) of VSVrp30a, VSV-GFP ... This replication-competent virus, the glioma-adapted vesicular stomatis virus strain VSVrp30a, was used for in vivo tests with ...
  http://www.jneurosci.org/content/28/8/1882?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=1&author1=van+den+Pol&andorexacttitle=and&andorexacttitleabs=and&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&fdate=2%2F1%2F2008&resourcetype=HWCIT
*  MADH9 | Application of Computational Methods for the Design of BACE-1 Inhibitors
Soluble THY-1 proteins clogged HCMV contamination during, but not really after, computer virus internalization. Manifestation ... therefore links computer virus access with signaling in sponsor cells that eventually prospects to computer virus contamination ... THY-1 may function through a complicated Compound W IC50 establishing, that would consist of virus-like gigabyte and gH, and ... Writer Overview Human being cytomegalovirus (HCMV) is usually an essential human being virus that infects about half the US ...
  http://world-of-links.com/tag/madh9/
*  Patent US7507873 - Transgenic avians containing recombinant ovomucoid promoters - Google Patents
Targeting viruses and cells for selective internalization by cells. WO1992019749A1. May 1, 1992. Nov 12, 1992. The Board Of ... influenza virus, polio virus, pox virus, retrovirus, and the like, vectors derived from bacteriophage nucleic acid, e.g., ... Recombinant viruses can also be generated by transfection of plasmids into cells infected with virus. Suitable vectors include ... The recombinant nucleic acid molecules of the present invention can be delivered to cells using viruses such as vaccinia virus ...
  http://www.google.com/patents/US7507873?dq=5920316
*  Patente US5693509 - Adenovirus for delivering foreign DNA into higher eukaryotic cells - Google Patentes
The modified virus or cell binds the receptor in vive and is internalized by the target cell. The method provides vectors for ... A molecule Specific for a receptor on the surface of the target cell is introduced onto the surface of the virus or cell. ... Viruses or cells are targeted for selective internalization into a target in vive. ... Whilst the binding of the virus to these cells is reduced by a factor of two to five, the internalisation of the bound virus is ...
  http://www.google.es/patents/US5693509?dq=flatulence