*  Measuring Attachment and Internalization of Influenza A Virus in A549 Cells by Flow Cytometry | Protocol (Translated to...
Pohl, M. O., Stertz, S. Measuring Attachment and Internalization of Influenza A Virus in A549 Cells by Flow Cytometry. J. Vis. ... Overfør virus til et ultrasentrifugerør og fylle røret med PBS for å nå en sluttvolum på 30 ml. Spin virus på 112 389 xg i 90 ... MERK: Prosentandelen av vedlagte virus er beskrevet av '0 min' sample. * For å beregne mengden av internalisert virus, ta ... Den relative mengde av internalisert virus kan beregnes som forholdet mellom internalisert virus (målt i '30 min + STV 'sample ...
  https://www.jove.com/video/53372/mling-vedlegg-og-internalisering-av-influensa-virus-i-a549-celler-ved?language=Norwegian
*  VSV-G pseudotyping allows HIV-2 entry in MDDCs. (a) HIV | Open-i
The viruses bound to the cells in a dose dependent manner (Figure 4a). VSV-G pseudotyping resulted in a slight but non- ... The viruses bound to the cells in a dose dependent manner (Figure 4a). VSV-G pseudotyping resulted in a slight but non- ... Background: Human Immunodeficiency Virus-type 2 (HIV-2) encodes Vpx that degrades SAMHD1, a cellular restriction factor active ... Background: Human Immunodeficiency Virus-type 2 (HIV-2) encodes Vpx that degrades SAMHD1, a cellular restriction factor active ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4307230_12977_2014_131_Fig4_HTML&req=4
*  Lassa virus - Wikipedia
It was reported that virus internalization is limited upon cholesterol depletion. The receptor used for cell entry is alpha- ... Lassa virus Lassa virus (LASV) is an arenavirus that causes Lassa hemorrhagic fever,[1] a type of viral hemorrhagic fever (VHF ... Lassa viruses[12][13] are enveloped, single-stranded, bisegmented, ambisense RNA viruses. Their genome[14] is contained in two ... Lassa virus is an emerging virus and a select agent, requiring Biosafety Level 4-equivalent containment. It is endemic in West ...
  https://en.wikipedia.org/wiki/Lassa_virus
*  Molecular Signaling and Cellular Pathways for Virus Entry
Although many viruses had shown that their internalization relied on the CME [2-7], the signals that are triggered by viruses ... including vaccinia virus, HIV-1, coxsackievirus B (CVB), herpes simplex virus type 1 (HSV-1), african swine fever virus (ASFV ... many microorganisms or viruses like Rift Valley fever virus (RVFV), herpesviruses, and adeno-associated virus (AAV) also ... but in some viruses like Influenza A virus and semliki forest virus (SFV), are associated with the sorting and transport to LE ...
  https://www.hindawi.com/journals/isrn/2013/306595/
*  Generation and characterization of the GGR Affinofile C | Open-i
16-21 hours post-seeding/induction, cells were infected with wt JR-CSF virus at varying multiplicities of infection (MOI). The ... 16-21 hours post-seeding/induction, cells were infected with wt JR-CSF virus at varying multiplicities of infection (MOI). The ... and infected as above with pseudotyped virus at an MOI of 0.25. Three days post-infection, supernatant was collected and ... and infected as above with pseudotyped virus at an MOI of 0.25. Three days post-infection, supernatant was collected and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4230403_1742-4690-11-48-1&req=4
*  Integrin traffic | Journal of Cell Science
Several viruses also use integrins for their internalization (see Table 1). Echovirus1 and rotavirus enter cells via α2β1- ... O'Donnell, V., LaRocco, M., Duque, H. and Baxt, B. (2005). Analysis of foot-and-mouth disease virus internalization events in ... However, internalization of α5β1 integrin is not impaired by these mutations to the β1 tail despite the fact that it is ... Peng, J. M., Liang, S. M. and Liang, C. M. (2004). VP1 of foot-and-mouth disease virus induces apoptosis via the Akt signaling ...
  http://jcs.biologists.org/content/119/18/3723
*  WWP2 - Wikipedia
Galinier R, Gout E, Lortat-Jacob H, Wood J, Chroboczek J (2003). "Adenovirus protein involved in virus internalization recruits ... "Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine ...
  https://en.wikipedia.org/wiki/WWP2
*  WWP1 - Wikipedia
Galinier R, Gout E, Lortat-Jacob H, Wood J, Chroboczek J (2003). "Adenovirus protein involved in virus internalization recruits ...
  https://en.wikipedia.org/wiki/WWP1
*  A cell-based dual-reporter system for monitoring HCV in | Open-i
The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular carcinomas ... The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular carcinomas ... Bottom Line: The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular ... Bottom Line: The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4352851_srep08865-f1&req=4
*  Host-cell-dependent role of actin cytoskeleton during the replication of a human strain of influenza A virus, Archives of...
"Host-cell-dependent role of actin cytoskeleton during the replication of a human strain of influenza A virus, Archives of ... Clustering of mutant influenza virus hemagglutinins into coated pits depends on the strength of the internalisation signal ... Association of influenza virus NP and M1 proteins with cellular cytoskeletal elements in influenza virus-infected cells ... Role of the actin cytoskeleton during influenza virus internalization into polarized epithelial cells ...
  https://www.deepdyve.com/lp/springer_journal/host-cell-dependent-role-of-actin-cytoskeleton-during-the-replication-BQd43VZ2Up
*  Integrated analysis of mRNA-seq and miRNA-seq for host susceptibilities to influenza A (H7N9) infection in inbred mouse lines |...
Fujioka Y et al (2013) A Ca(2+)-dependent signalling circuit regulates influenza A virus internalization and infection. Nat ... The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile Virus, and Dengue Virus. Cell 139:1243-1254 ... Cheung CY et al (2012) H5N1 virus causes significant perturbations in host proteome very early in influenza virus-infected ... The Ras-PI3K signaling pathway is involved in clathrin-independent endocytosis and the internalization of influenza viruses. ...
  https://link.springer.com/article/10.1007/s10142-018-0602-3
*  Adenovirus receptors and their implications in gene delivery
Virus Res. 2004;105:127-136. [PubMed]. *Bangari DS, Mittal SK. Porcine adenovirus serotype 3 internalization is independent of ... Besides internalization, the integrin αvβ5 plays a major role in membrane permeabilization and virus escape into the cytosol ( ... Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell. 1993;73:309-319. ... Virus taxonomy: Eighth Report of the International Committee on the Taxonomy of Viruses. Elsevier Academic Press; San Diego: ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2903974/
*  Research programme: anti-hepatitis C virus monoclonal antibodies - GENimmune - AdisInsight
Mechanism of Action Immunomodulators; Virus internalisation inhibitors * Orphan Drug Status Orphan designation is assigned by a ... Research programme: anti-hepatitis C virus monoclonal antibodies - GENimmune Alternative Names: ED 004; GNI 104; HCV hu mAbs - ... A lead monoclonal antibody receives orphan drug status from the European Commission for the prevention of hepatitis C virus re- ...
  https://adisinsight.springer.com/drugs/800027514?error=cookies_not_supported&code=7121b27c-fc26-486d-b151-8bcf123a97da
*  The rate-shifting pattern at site 414 of gp120, display | Open-i
One may speculate that these subtypes infect patients where a certain allele of CCR5 is more common, and the virus has adapted ... One may speculate that these subtypes infect patients where a certain allele of CCR5 is more common, and the virus has adapted ... A hallmark of the human immunodeficiency virus 1 (HIV-1) is its rapid rate of evolution within and among its various subtypes. ... For instance, the CCR5 Δ32 mutation is known to confer reduced susceptibility to the virus in Europe and western Asia [45], and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2566816_pcbi.1000214.g004&req=4
*  IFITM-mediated restriction of virus-endosome fusion in | Open-i
IFITM-mediated restriction of virus-endosome fusion in different cell types.(A) IFITM3-mediated inhibition of viral fusion with ... Here, we examined IAV restriction by IFITM3 protein using direct virus-cell fusion assay and single virus imaging in live cells ... Here, we examined IAV restriction by IFITM3 protein using direct virus-cell fusion assay and single virus imaging in live cells ... IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3974867_ppat.1004048.g001&req=4
*  Real-time PCR analysis of expression profiles of BmNPV | Open-i
A virus overlay assay was used to detect B. mori proteins that specifically bind to BmNPV particles. Twelve proteins were ... A virus overlay assay was used to detect B. mori proteins that specifically bind to BmNPV particles. Twelve proteins were ... vacuolar ATP synthase catalytic subunit A and subunit B may be implicated in the process of the membrane fusion of virus and ... vacuolar ATP synthase catalytic subunit A and subunit B may be implicated in the process of the membrane fusion of virus and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4264868_pone.0115032.g004&req=4
*  Pak1 is required for ASFV entry in Vero cells.A) ASFV a | Open-i
African swine fever (ASF) is caused by a large and highly pathogenic DNA virus, African swine fever virus (ASFV), which ... We have also found that internalization of the virions depends on actin reorganization, activity of Na(+)/H(+) exchangers, and ... African swine fever (ASF) is caused by a large and highly pathogenic DNA virus, African swine fever virus (ASFV), which ... African swine fever virus uses macropinocytosis to enter host cells. Sánchez EG, Quintas A, Pérez-Núñez D, Nogal M, Barroso S, ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3375293_ppat.1002754.g007&req=4
*  "Arenaviruses: mechanisms of antibody-mediated neutralization and an al" by Rachel Bottjen Brouillette
Junín virus (JUNV), and Lassa virus (LASV), are causative agents of Bolivian hemorrhagic fever, Argentine hemorrhagic fever, ... all three viruses are considered category A priority pathogens by the CDC. Arenavirus glycoproteins (GPCs) are considered class ... The three arenaviruses studied in this thesis, Machupo virus (MACV), ... This provides evidence that mechanism of virus internalization is viral glycoprotein-dependent and cell surface receptor- ...
  http://ir.uiowa.edu/etd/5429/
*  Plus it
... which allows virus attachment but not fusion and internalization) to 37°C (which allows virus fusion and internalization; ... "bound virus") and internalization into ("internalized virus") the cell. Viral DNA was quantified by qRT-PCR and results ... to allow virus internalization) before being harvested by trypsinization for DNA quantification by qRT-PCR. ... and hCMV DNA was expressed as the percentage of virus bound (the "attachment" step) or internalized (the "internalization" step ...
  http://www.jneurosci.org/content/37/29/6877
*  Surface plasmon resonance showed papuamide A did not in | Open-i
HIV pseudotype viruses expressing envelope glycoproteins from vesicular stomatitis virus or amphotropic murine leukemia virus ... HIV pseudotype viruses expressing envelope glycoproteins from vesicular stomatitis virus or amphotropic murine leukemia virus ... We show here that papuamide A acts as an entry inhibitor, preventing human immunodeficiency virus infection of host cells and ... We show here that papuamide A acts as an entry inhibitor, preventing human immunodeficiency virus infection of host cells and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2630844_md-06-00528f3&req=4
*  Effects of Oils and Essential Oils from Seeds of Zanthoxylum schinifolium against Foodborne Viral Surrogates
... internalization of virion into the cell, replication of the virus, and release of the mature virion from the cell [26]. ... herpes simplex virus type 1 (HSV-1) [13], HSV-2 [14], dengue virus type 2, and Junin virus [15]. Even though essential oils ... and posttreatments can test inhibition of virus internalization and replication, respectively.. For FCV-F9, strong inhibition ... When ZSO was added simultaneously to the cells with virus or the virus was posttreated with ZSO, plaque formation was inhibited ...
  https://www.hindawi.com/journals/ecam/2014/135797/
*  Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo. ...
2-4. β3 integrin interaction with virus RGD motifs triggers intracellular signaling that promotes virus internalization into ... Mice were injected intravenously with a high dose of the indicated viruses (1011 virus particles per mouse), and 3 hours later ... Transcriptional and functional activation of IL-1α in response to ts1 mutant virus and the model of IL-1α-mediated activation ... Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo. ...
  https://www.ncbi.nlm.nih.gov/pubmed/19576795
*  'influenza a virus' Protocols and Video...
Measuring Attachment and Internalization of Influenza A Virus in A549 Cells by Flow Cytometry', 'Co-immunoprecipitation of the ... Influenza A Virus Studies in a Mouse Model of Infection', 'Using Zebrafish Models of Human Influenza A Virus Infections to ... Influenza Virus Propagation in Embryonated Chicken Eggs', 'Expression and Purification of Virus-like Particles for Vaccination ... Mouse Mx1 Protein with the Influenza A Virus Nucleoprotein', 'Nasal Wipes for Influenza A Virus Detection and Isolation from ...
  https://www.jove.com/keyword/influenza+a+virus
*  HAVCR1 - Wikipedia
TIM-1 enhanced dengue virus infectivity by 500-fold, particularly increased virus internalization. TIM-1 directly interacted ... TIM-1 binds to Ebola virus glycoproteins (GP) and mediates Ebola virus cellular entry by increasing Ebola virus infectivity in ... that include viruses such as dengue and ebola. Interestingly entry of Lassa fever virus, influenza A virus, and SARS ... is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus- ...
  https://en.wikipedia.org/wiki/HAVCR1
*  FUSION PROTEINS - Patent application
... vesicular stomatitis virus (VSV) glycoprotein G, a translocating domain of SER virus F protein and a translocating domain of ... Binding Site is capable of internalisation (e.g. endosome formation)--also referred to as receptor-mediated endocytosis. The TM ... SER virus F protein Translocation domain Seth et al., 2003, J Virol 77(11) 6520-6527 Foamy virus Translocation domain Picard- ... 32. A method according to claim 31, wherein the protease is selected from Enterokinase, Factor Xa, Tobacco Etch virus (TEV), ...
  http://www.patentsencyclopedia.com/app/20120064059