*  Measuring Attachment and Internalization of Influenza A Virus in A549 Cells by Flow Cytometry | Protocol (Translated to...
Pohl, M. O., Stertz, S. Measuring Attachment and Internalization of Influenza A Virus in A549 Cells by Flow Cytometry. J. Vis. ... Overfør virus til et ultrasentrifugerør og fylle røret med PBS for å nå en sluttvolum på 30 ml. Spin virus på 112 389 xg i 90 ... MERK: Prosentandelen av vedlagte virus er beskrevet av '0 min' sample. * For å beregne mengden av internalisert virus, ta ... Den relative mengde av internalisert virus kan beregnes som forholdet mellom internalisert virus (målt i '30 min + STV 'sample ...
  https://www.jove.com/video/53372/mling-vedlegg-og-internalisering-av-influensa-virus-i-a549-celler-ved?language=Norwegian
*  Lassa virus - Wikipedia
It was reported that virus internalization is limited upon cholesterol depletion. The receptor used for cell entry is alpha- ... Lassa virus Lassa virus (LASV) is an arenavirus that causes Lassa hemorrhagic fever,[1] a type of viral hemorrhagic fever (VHF ... Lassa viruses[12][13] are enveloped, single-stranded, bisegmented, ambisense RNA viruses. Their genome[14] is contained in two ... Lassa virus is an emerging virus and a select agent, requiring Biosafety Level 4-equivalent containment. It is endemic in West ...
  https://en.wikipedia.org/wiki/Lassa_virus
*  Molecular Signaling and Cellular Pathways for Virus Entry
Although many viruses had shown that their internalization relied on the CME [2-7], the signals that are triggered by viruses ... including vaccinia virus, HIV-1, coxsackievirus B (CVB), herpes simplex virus type 1 (HSV-1), african swine fever virus (ASFV ... many microorganisms or viruses like Rift Valley fever virus (RVFV), herpesviruses, and adeno-associated virus (AAV) also ... but in some viruses like Influenza A virus and semliki forest virus (SFV), are associated with the sorting and transport to LE ...
  https://www.hindawi.com/journals/isrn/2013/306595/
*  Generation and characterization of the GGR Affinofile C | Open-i
16-21 hours post-seeding/induction, cells were infected with wt JR-CSF virus at varying multiplicities of infection (MOI). The ... 16-21 hours post-seeding/induction, cells were infected with wt JR-CSF virus at varying multiplicities of infection (MOI). The ... and infected as above with pseudotyped virus at an MOI of 0.25. Three days post-infection, supernatant was collected and ... and infected as above with pseudotyped virus at an MOI of 0.25. Three days post-infection, supernatant was collected and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4230403_1742-4690-11-48-1&req=4
*  A cell-based dual-reporter system for monitoring HCV in | Open-i
The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular carcinomas ... The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular carcinomas ... Bottom Line: The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular ... Bottom Line: The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4352851_srep08865-f1&req=4
*  Integrin traffic | Journal of Cell Science
Several viruses also use integrins for their internalization (see Table 1). Echovirus1 and rotavirus enter cells via α2β1- ... O'Donnell, V., LaRocco, M., Duque, H. and Baxt, B. (2005). Analysis of foot-and-mouth disease virus internalization events in ... However, internalization of α5β1 integrin is not impaired by these mutations to the β1 tail despite the fact that it is ... Peng, J. M., Liang, S. M. and Liang, C. M. (2004). VP1 of foot-and-mouth disease virus induces apoptosis via the Akt signaling ...
  http://jcs.biologists.org/content/119/18/3723
*  Host-cell-dependent role of actin cytoskeleton during the replication of a human strain of influenza A virus, Archives of...
"Host-cell-dependent role of actin cytoskeleton during the replication of a human strain of influenza A virus, Archives of ... Clustering of mutant influenza virus hemagglutinins into coated pits depends on the strength of the internalisation signal ... Association of influenza virus NP and M1 proteins with cellular cytoskeletal elements in influenza virus-infected cells ... Role of the actin cytoskeleton during influenza virus internalization into polarized epithelial cells ...
  https://www.deepdyve.com/lp/springer_journal/host-cell-dependent-role-of-actin-cytoskeleton-during-the-replication-BQd43VZ2Up
*  WWP2 - Wikipedia
Galinier R, Gout E, Lortat-Jacob H, Wood J, Chroboczek J (2003). "Adenovirus protein involved in virus internalization recruits ... "Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine ...
  https://en.wikipedia.org/wiki/WWP2
*  WWP1 - Wikipedia
Galinier R, Gout E, Lortat-Jacob H, Wood J, Chroboczek J (2003). "Adenovirus protein involved in virus internalization recruits ...
  https://en.wikipedia.org/wiki/WWP1
*  Research programme: anti-hepatitis C virus monoclonal antibodies - GENimmune - AdisInsight
Mechanism of Action Immunomodulators; Virus internalisation inhibitors * Orphan Drug Status Orphan designation is assigned by a ... Research programme: anti-hepatitis C virus monoclonal antibodies - GENimmune Alternative Names: ED 004; GNI 104; HCV hu mAbs - ... A lead monoclonal antibody receives orphan drug status from the European Commission for the prevention of hepatitis C virus re- ...
  https://adisinsight.springer.com/drugs/800027514?error=cookies_not_supported&code=7121b27c-fc26-486d-b151-8bcf123a97da
*  The rate-shifting pattern at site 414 of gp120, display | Open-i
One may speculate that these subtypes infect patients where a certain allele of CCR5 is more common, and the virus has adapted ... One may speculate that these subtypes infect patients where a certain allele of CCR5 is more common, and the virus has adapted ... A hallmark of the human immunodeficiency virus 1 (HIV-1) is its rapid rate of evolution within and among its various subtypes. ... For instance, the CCR5 Δ32 mutation is known to confer reduced susceptibility to the virus in Europe and western Asia [45], and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2566816_pcbi.1000214.g004&req=4
*  IFITM-mediated restriction of virus-endosome fusion in | Open-i
IFITM-mediated restriction of virus-endosome fusion in different cell types.(A) IFITM3-mediated inhibition of viral fusion with ... Here, we examined IAV restriction by IFITM3 protein using direct virus-cell fusion assay and single virus imaging in live cells ... Here, we examined IAV restriction by IFITM3 protein using direct virus-cell fusion assay and single virus imaging in live cells ... IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3974867_ppat.1004048.g001&req=4
*  Real-time PCR analysis of expression profiles of BmNPV | Open-i
A virus overlay assay was used to detect B. mori proteins that specifically bind to BmNPV particles. Twelve proteins were ... A virus overlay assay was used to detect B. mori proteins that specifically bind to BmNPV particles. Twelve proteins were ... vacuolar ATP synthase catalytic subunit A and subunit B may be implicated in the process of the membrane fusion of virus and ... vacuolar ATP synthase catalytic subunit A and subunit B may be implicated in the process of the membrane fusion of virus and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4264868_pone.0115032.g004&req=4
*  Pak1 is required for ASFV entry in Vero cells.A) ASFV a | Open-i
African swine fever (ASF) is caused by a large and highly pathogenic DNA virus, African swine fever virus (ASFV), which ... We have also found that internalization of the virions depends on actin reorganization, activity of Na(+)/H(+) exchangers, and ... African swine fever (ASF) is caused by a large and highly pathogenic DNA virus, African swine fever virus (ASFV), which ... African swine fever virus uses macropinocytosis to enter host cells. Sánchez EG, Quintas A, Pérez-Núñez D, Nogal M, Barroso S, ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3375293_ppat.1002754.g007&req=4
*  "Arenaviruses: mechanisms of antibody-mediated neutralization and an al" by Rachel Bottjen Brouillette
Junín virus (JUNV), and Lassa virus (LASV), are causative agents of Bolivian hemorrhagic fever, Argentine hemorrhagic fever, ... all three viruses are considered category A priority pathogens by the CDC. Arenavirus glycoproteins (GPCs) are considered class ... The three arenaviruses studied in this thesis, Machupo virus (MACV), ... This provides evidence that mechanism of virus internalization is viral glycoprotein-dependent and cell surface receptor- ...
  http://ir.uiowa.edu/etd/5429/
*  Surface plasmon resonance showed papuamide A did not in | Open-i
HIV pseudotype viruses expressing envelope glycoproteins from vesicular stomatitis virus or amphotropic murine leukemia virus ... HIV pseudotype viruses expressing envelope glycoproteins from vesicular stomatitis virus or amphotropic murine leukemia virus ... We show here that papuamide A acts as an entry inhibitor, preventing human immunodeficiency virus infection of host cells and ... We show here that papuamide A acts as an entry inhibitor, preventing human immunodeficiency virus infection of host cells and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2630844_md-06-00528f3&req=4
*  Adenovirus receptors and their implications in gene delivery
Virus Res. 2004;105:127-136. [PubMed]. *Bangari DS, Mittal SK. Porcine adenovirus serotype 3 internalization is independent of ... Besides internalization, the integrin αvβ5 plays a major role in membrane permeabilization and virus escape into the cytosol ( ... Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell. 1993;73:309-319. ... Virus taxonomy: Eighth Report of the International Committee on the Taxonomy of Viruses. Elsevier Academic Press; San Diego: ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2903974/
*  Plus it
... which allows virus attachment but not fusion and internalization) to 37°C (which allows virus fusion and internalization; ... "bound virus") and internalization into ("internalized virus") the cell. Viral DNA was quantified by qRT-PCR and results ... to allow virus internalization) before being harvested by trypsinization for DNA quantification by qRT-PCR. ... and hCMV DNA was expressed as the percentage of virus bound (the "attachment" step) or internalized (the "internalization" step ...
  http://www.jneurosci.org/content/37/29/6877
*  RG 6024 - AdisInsight
Mechanism of Action Virus internalisation inhibitors * Orphan Drug Status Orphan designation is assigned by a regulatory body ... Phase I Influenza B virus infections Most Recent Events * 01 Jan 2016 Genentech completes a phase I trial in Influenza-B virus ... 22 Oct 2015 Phase-I clinical trials in Influenza-B virus infections (In volunteers) in Canada (IV) (NCT02528903) ... 24 Aug 2015 Genentech plans a phase I trial for Influenza B virus infections in Canada (NCT02528903) ...
  http://adisinsight.springer.com/drugs/800043112?error=cookies_not_supported&code=c8bd8115-dff5-459c-b2a5-a61bbc065559
*  Characterization of hepatitis C Virus genotype 3a hypervariable region 1 in patients achieved rapid virological response to...
Hepatitis C virus roots a chronic liver disease. Currently approved treatment strategy includes administration of alpha ... and GAG's that are proposed to be involved in virus internalization [22] and receptor virus interaction [23] respectively ... Agnello V,Abel G,Elfahal M,Knight GB,Zhang QX,Hepatitis C virus and other flaviviridae viruses enter cells via low density ... Pretreatment serum hepatitis C virus RNA levels and hepatitis C virus genotype are the main and independent prognostic factors ...
  http://www.biomedsearch.com/nih/Characterization-Hepatitis-C-Virus-genotype/21605410.html
*  Anti-Rhinovirus Activity of Ethyl 4-(3-(2-(3-Methylisoxazol-5-Yl) Ethoxy) Propoxy) Benzoate (EMEB) | OMICS International
... the virus internalization into the cells, the viral uncoating, transcription and translation, and finally on viral ... by analysing its adhesion to the cell virus internalization into the cells, the viral uncoating, transcription and translation ... Viruses and cell lines. Rhinovirus HRV 14 and HRV 39. Isolated from throat washings of patients with respiratory illness [4-7 ... Neutral redi s added to the medium; cells not damaged by virus take up a greater amount of dye, which is read on a computerized ...
  https://www.omicsonline.org/open-access/antirhinovirus-activity-of-ethyl-4323methylisoxazol5yl-ethoxypropoxy-benzoate-emeb-2153-2435-1000469.php?aid=71077
*  Herpes Simplex Virus Glycoproteins H/L Bind to Cells Independently of αVβ3 Integrin and Inhibit Virus Entry, and Their...
... induction of signaling activities that target virus internalization, modification of the cellular cytoskeleton, etc. A similar ... Herpes simplex virus glycoprotein D mediates interference with herpes simplex virus infection. J. Virol. 63:819-827. [PMC free ... Herpes simplex virus glycoprotein B binds to cell surfaces independently of heparan sulfate and blocks virus entry. J. Virol. ... Herpes Simplex Virus Glycoproteins H/L Bind to Cells Independently of αVβ3 Integrin and Inhibit Virus Entry, and Their ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2849490/
*  'influenza a virus' Protocols and Video...
Measuring Attachment and Internalization of Influenza A Virus in A549 Cells by Flow Cytometry', 'Co-immunoprecipitation of the ... Influenza A Virus Studies in a Mouse Model of Infection', 'Using Zebrafish Models of Human Influenza A Virus Infections to ... Influenza Virus Propagation in Embryonated Chicken Eggs', 'Expression and Purification of Virus-like Particles for Vaccination ... Mouse Mx1 Protein with the Influenza A Virus Nucleoprotein', 'Nasal Wipes for Influenza A Virus Detection and Isolation from ...
  https://www.jove.com/keyword/influenza+a+virus
*  Viruses | Free Full-Text | Endocytic Pathways Involved in Filovirus Entry: Advances, Implications and Future Directions | HTML
While it is generally agreed that filovirus entry into the host cytoplasm requires viral internalization into acidic endosomal ... Detailed knowledge of the host-virus interactions that accompany filovirus entry into cells is expected to identify ... Bundibugyo virus [BDBV], Ebola virus [EBOV], Sudan virus [SUDV]) and one marburgvirus (Marburg virus [MARV]) are associated ... Nemerow, G.R.; Cooper, N.R. Early events in the infection of human B lymphocytes by Epstein-Barr virus: The internalization ...
  http://mdpi.com/1999-4915/4/12/3647/htm
*  FUSION PROTEINS - Patent application
... vesicular stomatitis virus (VSV) glycoprotein G, a translocating domain of SER virus F protein and a translocating domain of ... Binding Site is capable of internalisation (e.g. endosome formation)--also referred to as receptor-mediated endocytosis. The TM ... SER virus F protein Translocation domain Seth et al., 2003, J Virol 77(11) 6520-6527 Foamy virus Translocation domain Picard- ... 32. A method according to claim 31, wherein the protease is selected from Enterokinase, Factor Xa, Tobacco Etch virus (TEV), ...
  http://www.patentsencyclopedia.com/app/20120064059