Successful treatment of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Delays in treatment for acute leukemia can adversely affect maternal prognosis, but chemotherapy during pregnancy may induce ... She underwent remission induction therapy including daunorubicin, vincristine, cyclophosphamide, and prednisolone. Imatinib was ... who underwent remission induction therapy and successfully delivered a live infant after chemotherapy. The case is a 36-year- ... Delays in treatment for acute leukemia can adversely affect maternal prognosis, but chemotherapy during pregnancy may induce ...http://www.biomedsearch.com/nih/Successful-treatment-pregnant-woman-with/23359302.html
Acute lymphoblastic leukemia in adults: recent progress, future directions
Most patients, greater than 70% to 80%, will achieve a remission following induction chemotherapy with vincristine, prednisone ... In recent studies with intensive treatment, time to response, age, WBC, immunologic subtype and cytogenetic data can be used to ... Additional drugs do not convincingly increase the remission rate; their effect on remission duration is unknown. Although ... The precise value of conventional maintenance chemotherapy in adult ALL is unknown. CNS prophylaxis is necessary; the standard ...https://imsdd.meb.uni-bonn.de/cgi-bin/mycite?ExtRef=MEDL/87149134/PMID/3547671
Complete response of extramedullary relapse in breast of acute T lymphoblastic leukemia after bone marrow transplantation to...
Combined modality treatment including chemotherapy and local radiotherapy helped achieve complete remission with mild side ... clinicians consider local relapse even if the bone marrow findings indicate remission. Combined modality treatment will ... Pathology investigation revealed breast relapse, with complete remission on the basis of bone marrow findings. ... Induction chemotherapy using a VDCLP (vincristine, daunorubicin, cyclophosphamide, L-asparaginase and prednisone) regimen ...https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2910-0
Leukemia - Wikipedia
In general, ALL treatment is divided into several phases: Induction chemotherapy to bring about bone marrow remission. For ... vincristine, prednisone CHOP, cyclophosphamide, vincristine, prednisone [COP], vincristine, doxorubicin, prednisone, etoposide ... Consolidation treatment often entails a repetition of induction chemotherapy or the intensification chemotherapy with ... induction phase of chemotherapy. Such combination chemotherapy usually offers the benefits of early remission and a lower risk ...https://en.wikipedia.org/wiki/Leukemia
Acute biphenotypic leukaemia - Wikipedia
... most patients receive treatment based on the morphology of blasts and get AML or ALL induction chemotherapy. The induction drug ... For example, The chemotherapy for ALL and gemtuzuab ozogamicin without all-trans-retinoic acid remain complete remission of the ... for AML such as cytarabine and anthracycline, drug for ALL such as prednisolone, dexamethasone, vincristine, asparaginase or ... Recently, researches showed that using both myeloid and lymphoid induction therapy may be better for prognosis. Chemotherapy ...https://en.wikipedia.org/wiki/Acute_biphenotypic_leukaemia
The major treatment plans and modalities for each type are outlined below. ... Leukemia treatment is different for each of the types of leukemia. ... Induction treatment for ALL. Current induction treatment for children with high-risk ALL and all adults contain chemotherapy ... The aim of treatment is remission. Drug treatment is superior to allogeneic stem cell transplantation in CML patients. The most ...https://www.news-medical.net/health/Leukemia-Treatments.aspx
ASSESSMENT OF OBESITY AND HEPATIC LATE ADVERSE EFFECTS IN THE EGYPTIAN SURVIVORS OF PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA:...
... the remission induction therapy began with prednisone, vincristine, daunorubicin, and asparaginase. Subsequent remission ... All of them completed treatment with St Jude Total XV Chemotherapy Protocol 5 years before the time of examination. In that ... At the end of treatment and 5 years post-treatment, approximately 40% were overweight or obese. Weight gain during treatment ... and vincristine. Two re-induction treatments were given between weeks 7 to 9 and weeks 17 to 19. Patients with standard-risk ...http://www.mjhid.org/index.php/mjhid/article/view/2017.026/html
Recent advances in management of acute leukaemia | Archives of Disease in Childhood
... of treatment for ALL has remained unchanged for over 25 years and includes remission induction, treatment to prevent overt ... with periodic steroids and vincristine.24There is no evidence that, after the first 10-12 months of chemotherapy, more ... 1996) Treatment related deaths during induction and in first remission in acute lymphoblastic leukaemia: MRC UKALL X. Arch Dis ... INDUCTION AND INTENSIFICATION. Over 95% of children with ALL achieve remission after three to four weeks of treatment with oral ...http://adc.bmj.com/content/82/6/438
Late intensification with POMP chemotherapy prolongs survival in acute myelogenous leukemia - results of a Southwest Oncology...
i) What is the comparative utility of rubidazone versus Adriamycin in remission induction? (ii) What is the role of ... At twelve months of remission, surviving patients were randomized to receive levamisole or no further treatment. There was no ... vincristine + methotrexate + prednisone) or continued maintenance with OAP (vincristine + cytosine arabinoside + prednisone). ... results of a Southwest Oncology Group Study of Rubidazone versus Adriamycin for remission induction, prophylactic intrathecal ...http://imsdd.meb.uni-bonn.de/cgi-bin/mycite?ExtRef=MEDL/92326441/PMID/1625490
What is the Best Protocol for Canine Lymphoma? - WSAVA2007 - VIN
... the other dogs received 2 or 3 cycles of induction chemotherapy. Second remission rate for these dogs was 87%. Overall disease ... MOPP chemotherapy for treatment of resistant lymphoma in dogs: a retrospective study of 117 cases (1989-2000) J Vet Internal ... Third Level: The most effective chemotherapy protocols use a five-drug combination of L-asparaginase, vincristine, ... A combination chemotherapy protocol with MOPP and CCNU consolidation (Tufts VELCAP-SC) for the treatment of canine lymphoma. ...https://www.vin.com/apputil/content/defaultadv1.aspx?pId=11242&meta=Generic&catId=31932&id=3860739&ind=287&objTypeID=17
CHOEP + High Dose Therapy + Auto SCT for T-Cell Lymphoma - Full Text View - ClinicalTrials.gov
Intervention/treatment Experimental: CHOEP + High Dose Therapy + Auto SCT Patients received 6 cycles of induction chemotherapy ... Induction response is the defined as the proportion of patients who achieve complete remission (CR) or partial remission (PR) ... Intervention/treatment Phase T-cell Non-Hodgkin Lymphoma Drug: Cyclophosphamide Drug: Doxorubicin Drug: Vincristine Drug: ... The current standard of care for the frontline treatment of peripheral T-cell lymphomas (PTCL) is induction chemotherapy ...https://clinicaltrials.gov/ct2/show/study/NCT01746173
Decision Making in Feline Cancer Patients - WSAVA2008 - VIN
Numerous treatment protocols have been described for feline lymphoma. Most use vincristine, cyclophosphamide and prednisolone ... FeLV negative cats that achieve a complete remission following induction therapy are likely to have durable (i.e., , 6 month) ... Chemotherapy. Chemotherapy has shown little consistent efficacy in the veterinary literature. Agents that have been used ... standard treatment protocols and advances in radiation and chemotherapy-based treatments. Particular emphasis will be placed ...http://www.vin.com/apputil/content/defaultadv1.aspx?pId=11268&id=3866631
ALL Adult Consortium Trial: Adult ALL Trial - Tabular View - ClinicalTrials.gov
Induction is used to cause a remission. Eight drugs are used during this phase of treatment, and administration is either ... If they are not in complete remission, they will receive vincristine by IV on days 32, 39 and 46, until complete remission is ... This consolidation treatment consists of 3 phases: 1A, 1B and 1C. Each phase involves a three week cycle of chemotherapy. Arm A ... If they have achieved complete remission or partial remission, they will proceed to the next phase of treatment. ...https://clinicaltrials.gov/ct2/show/record/NCT00476190
Combination Chemotherapy in Treating Pediatric Patients With Advanced-Stage Large Cell Lymphoma - Full Text View -...
Induction: Patients receive treatment as in arm I except that patients with CNS disease also receive methotrexate IT on days 15 ... Patients in complete remission on day 43 proceed to maintenance, those in partial remission undergo biopsy then proceed to ... Modified APO: Patients receive vincristine IV on day 1, oral mercaptopurine on days 1-5, doxorubicin IV over 15 minutes on day ... Intervention/treatment Phase Lymphoma Biological: filgrastim Drug: cytarabine Drug: doxorubicin hydrochloride Drug: leucovorin ...https://clinicaltrials.gov/ct2/show/NCT00002618
Acute Lymphoblastic Leukemia in Elderly Patients: A Single Institution's Experience
Post-remission treatment was also analyzed. The VP regimen (vincristine 1.5 mg/m2 D1 and prednisolone 40 mg/m2 D1-5) was used ... Chemotherapy regimen. The most commonly used regimen for induction therapy was a VPDL regimen of vincristine (1.5 mg/m2, D1, 8 ... Although intensified induction chemotherapy was not introduced, and post-remission therapy was not performed appropriately in ... A randomized controlled trial of filgrastim during remission induction and consolidation chemotherapy for adults with acute ...http://www.kjim.org/journal/view.php?number=162529
Adult Acute Lymphoblastic Leukemia: Remission Induction - UNM Comprehensive Cancer Center
Currently, 90% of adults with ALL will achieve a complete remission following initial multiagent chemotherapy treatment. ... Drugs used during remission induction usually include Oncovin® (vincristine), Elspar® (L-asparaginase) or Oncaspar® (peg-L- ... Therapy is divided into two phases, remission induction and post-remission therapy. Remission induction chemotherapy is ... remission induction rate following remission induction treatment with Cerubidine® (daunorubicin), Oncovin, prednisone, and ...http://cancer.unm.edu/2008/10/01/adult-acute-lymphoblastic-leukemia-remission-induction/
Asparaginase facts, information, pictures | Encyclopedia.com articles about Asparaginase
Induction therapy. -The first stage in treatment of ALL. The purpose of this stage is to quickly cause remission of the disease ... INDUCTION CHEMOTHERAPY FOR ALL.. Doses vary between different chemotherapy protocols. The usual dose is 6, 000-10, 000 units ... The combination of vincristine, asparaginase, and steroids make up the foundation of induction regimen. ... Asparaginase is used as part of an induction regimen for the treatment of acute lymphocytic leukemia (ALL) in children. ...https://www.encyclopedia.com/medicine/drugs/pharmacology/asparaginase
DiVA - Search result
Conclusion Dose-dense induction followed by HDT/ASCT was well tolerated and led to long-term PFS in 44% of treatment-naive ... An induction regimen of six cycles of biweekly CHOEP (cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone) ... In conclusion, despite half of the patients being still alive and 40% in first remission after more than 12years, we still see ... To evaluate the efficacy of a dose-dense approach consolidated by up-front high-dose chemotherapy (HDT) and autologous stem- ...http://uu.diva-portal.org/smash/resultList.jsf?af=%5B%5D&aq=%5B%5B%7B%22personId%22%3A%22authority-person%3A11781%22%7D%5D%5D&aqe=%5B%5D&aq2=%5B%5B%5D%5D&language=en&query=
PD-L1 is upregulated by EBV-driven LMP1 through NF-κB pathway and correlates with poor prognosis in natural killer/T-cell...
All patients received induction chemotherapy followed by consolidative radiotherapy (RT) as their primary treatment. 66.2 % of ... Cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) in the treatment of stage IE/IIE extranodal natural killer/T ... as induction chemotherapeutic regimen in dosages as previously reported . Complete remission (CR) was achieved after ... For early-stage (stage I~II) NKTCL, RT has been well established as the primary treatment [5-7], and chemotherapy may yield ...https://jhoonline.biomedcentral.com/articles/10.1186/s13045-016-0341-7
Chemotherapy Protocol for a Dog Having Cancer Recurrence | petMD
Mahaney outlines the cancer treatment Cardiff will be receiving to prevent the aggressive cancer and tumors from returning now ... If Cardiff is still in remission after the eight week re-induction period, then his treatments will be given every 14 days for ... Oncovin (drug name Vincristine Sulfate). Like Cyclophosphamide, Oncovin is an alkylating agent that damages cell DNA and also ... This course of chemotherapy will also involve a new treatment called T-cell monoclonal antibody (MAb). It's an immunotherapy ...http://www.petmd.com/blogs/thedailyvet/patrick-mahaney/2015/november/after-cancer-remission-using-chemotherapy-prevent-re
adult acute non lymphocytic leukemia in remission 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Remission Induction. Treatment Outcome. Vincristine / administration & dosage. Vincristine / adverse effects. *MedlinePlus ... Following intensive chemotherapy, one died from acute leukaemia and the second is in complete remission. ... Remission Induction. Survival Analysis. Transplantation, Homologous. Treatment Outcome. *Genetic Alliance. consumer health - ... Remission Induction. Transplantation, Autologous. Transplantation, Homologous. Treatment Outcome. *Genetic Alliance. consumer ...http://www.bmlsearch.com/?kwr=adult+acute+non+lymphocytic+leukemia+in+remission+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
Brain Stem Glioma - Childhood | Children's Cancer Web
... were treated with intensive induction chemotherapy and simultaneous external beam irradiation. Chemotherapy was performed ... Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine and oral VP-16: a Children's ... Significant improvement in mood and remission in psychosis were noted after the eighth treatment. Comparison of 2-week pre-ECT ... Maintenance chemotherapy with carmustine, carboplatin and vincristine (8 cycles over a 1-year period) was given in those ...http://www.cancerindex.org/ccw/guide2ib.htm
Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia - Tabular View ...
Compare the remission induction, toxicity, and duration of remission in patients with newly diagnosed acute lymphoblastic ... A RANDOMIZED PHASE III TRIAL COMPARING DEXAMETHASONE WITH PREDNISONE IN INDUCTION TREATMENT AND BONE MARROW TRANSPLANTATION ... and vincristine as induction.. *Compare the survival and disease-free survival of patients treated with autologous bone marrow ... Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia. The safety and ...https://clinicaltrials.gov/ct2/show/record/NCT00002700?term=%28NOT+NOTEXT%29+%5BCITATIONS%5D
glutaminase: Topics by WorldWideScience.org
The use of conventional chemotherapy for induction of complete remission (CR results in profound anemia and thrombocytopenia ... After one 28-day cycle of treatment, the patient achieved complete remission with incomplete count recovery (CRi and after the ... Notwithstanding that myeloperoxidase-induced oxidative degradation of vincristine results in its lack of activity as ... Minimally-Myelosuppressive Asparaginase-Containing Induction Regimen for Treatment of a Jehovah's Witness with mutant IDH1/NPM1 ...https://worldwidescience.org/topicpages/g/glutaminase.html
Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With...
Intervention/treatment Experimental: Treatment (temsirolimus, combination chemotherapy) Patients receive dexamethasone PO or IV ... Treatment. Official Title:. A Phase 1 Study of Temsirolimus in Combination With Intensive Re-induction Therapy for Children ... To determine the complete remission (CR) rate in patients with ALL or NHL who receive this regimen. ... MRD levels present at the end of induction [ Time Frame: Up to 30 days post-treatment ]. Compared to a historical control in ...https://clinicaltrials.gov/ct2/show/NCT01403415?cond=%22Acute+lymphoblastic+leukemia%22&rank=10