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*  Calciseptine - Wikipedia
For example, cobra venom has been found to have a bioavailability of 41.7% when injected intramuscular, and for other venoms ... It makes up 2.8% of the venom of the Black Mamba. When first purified, the peptide was called protein E3, which was later ... Calciseptine (CaS) is a natural neurotoxin isolated from the black mamba Dendroaspis p. polylepis venom. This toxin consists of ... Calciseptine is a member of a family of toxic peptides found in snake venoms. Proteins from this family are small and consist ...
  https://en.wikipedia.org/wiki/Calciseptine
*  Simple Modeling
The Cobra Toxin from the cobra snake ranks among the world's most lethal venoms. Unlike many protein-based neurotoxins, this ... one of the strongest protein binding interactions known). When the Cobra venom neurotoxin binds to the receptor, the receptor ... Five disulphide bonds within such a small protein is unusual, but common within the extremely toxic snake venoms. The image, ... Once bound, the neurotoxin acts as a plug to the receptor and prevents the bound receptor from initiating a neural impulse. The ...
  http://www-personal.umich.edu/~lpt/Modeling/lab15.htm
*  Cobra venom molecule - Stock Image F006/9278 - Science Photo Library
... snake venom protein) from an Indochinese spitting cobra (Naja siamensis). This neurotoxin acts by blocking the acetylcholine ... Cobra venom. Molecular model of an alpha-cobratoxin ( ... snake venom protein) from an Indochinese spitting cobra (Naja ... neurotoxin, protein, proteomics, research, snake, strand, structure, tertiary structure, toxic, toxin, venom, white background ... Caption: Cobra venom. Molecular model of an alpha-cobratoxin ( ... Cobra venom molecule. F006/9278 Royalty Free. Request un- ...
  http://www.sciencephoto.com/media/525552/view
*  Caspian cobra - Wikipedia
A number of small nonenzymatic proteins are found in the venom, including neurotoxins and members of the cytotoxin family, ... The Caspian cobra (Naja oxiana), also called the Central Asian cobra, Oxus cobra or Russian cobra, a member of the family ... "Naja oxiana". Venom Street. Collector and Breeder of Asian Cobras. Venom Street. Retrieved 3 February 2012. "Naja oxiana". ... The Caspian cobra is the most venomous species of cobra in the world, slightly ahead of the Philippine cobra, based on a 1992 ...
  https://en.wikipedia.org/wiki/Caspian_cobra
*  Cobrotoxin from Naja naja atra Venom Ameliorates Adriamycin Nephropathy in Rats
Cobra venom from Naja naja atra comprises a variety of active peptides such as neurotoxin, cardiotoxin, and phospholipase A2 [ ... Total urinary protein concentration (grams per liter) was determined using the Bradford protein assay kit (Beyotime Institute ... a long-chain neurotoxin, from Thailand cobra venom has been demonstrated to have potent actions on inhibiting formalin-induced ... Y.-L. Xu, J.-Q. Kou, S.-Z. Wang, C.-X. Chen, and Z.-H. Qin, "Neurotoxin from Naja naja atra venom inhibits skin allograft ...
  https://www.hindawi.com/journals/ecam/2015/450581/
*  Natural Toxins 2 | SpringerLink
Structure and Function of Cobra Venom Factor, the Complement-Activating Protein in Cobra Venom ... For example, botulinum neurotoxins, which have been used in studies in the field of neurobiology, have also been used directly ... Structure and Functions of Coagulation Factor IX/Factor X-Binding Protein Isolated from the Venom of Trimeresurus flavoviridis ... Biochemical Studies On The Effect of Plotosus Lineatus Crude Venom (In Vivo) And Its Effect On Eac-Cells (In Vitro) ...
  https://link.springer.com/book/10.1007%2F978-1-4613-0361-9
*  Долгих Дмитрий Александрович - ИБХ РАН
Neurotoxin II from the venom of cobra Naja oxiana is a short type alpha-neurotoxin, which competitively inhibits nicotinic ... Cytotoxins or cardiotoxins is a group of polycationic toxins from cobra venom belonging to the 'three-finger' protein ... Systems previously elaborated for neurotoxin II from venom of the cobra Naja oxiana were tested for bacterial production of " ... Expression of neurotoxin II from Naja oxiana cobra venom in Escherichia coli in a hybrid form with thioredoxin]. Bioorg. Khim. ...
  http://www.ibch.ru/structure/groups/proteng/14
*  Javan spitting cobra - Wikipedia
... and they possess amino acid sequences similar to those of other cobra venom neurotoxins. The venom was also found to exhibit an ... The most significant constituents of the venom include high-molecular-weight proteins and enzymes, phospholipase A2 enzymes, ... sputa-neurotoxin 1 (SN1) and sputa-neurotoxin 2 (SN2) isolated from the venom, are "short" neurotoxins, with 62 and 61 amino ... Like all cobra species, this species' venom also consists of postsynaptic neurotoxins. However, the main components of its ...
  https://en.wikipedia.org/wiki/Javan_spitting_cobra
*  Antinociceptive and Anti-Inflammatory Effects of Orally Administrated Denatured Naja Naja Atra Venom on Murine Rheumatoid...
... α-neurotoxin: "cobratoxin" and short-chain α-neurotoxin: "cobrotoxin"), cardiotoxin, cobra venom factor (CVF), and so forth. ... According to the literature, the protein band of MW 7 KD contained cardiotoxin and neurotoxin [21, 22]. In contrast, heat ... It has been reported in Chinese literature that neurotoxin in cobra venom can be rapidly absorbed through rectal mucosa [14]. ... Similarly, oral administration of neurotoxin from king cobra venom produced the analgesic action [10]. Recently, the absorption ...
  https://www.hindawi.com/journals/ecam/2013/616241/
*  Sandwalk: August 2007
As it turns out, there are other things in the cobra venom that are even more lethal.. These other components of cobra venom ... The venom also includes a number of neurotoxins that gain access to the central nervous system when blood vessels break down. ... The combination of all these proteins can cause death within minutes of receiving a cobra bite. However, many people survive ... A picture of cobra venom phospholipase A2 bound to a lipid molecule (left) can be found in most biochemistry textbooks.. ...
  http://sandwalk.blogspot.co.nz/2007/08/
*  Коншина Анастасия Геннадьевна - ИБХ РАН
While neurotoxins (NTs) - also TF proteins from snake venom - exert their effect through specific interactions with protein ... Protein Pept. Sci. 13 (6), 570-84 [+]. Cytotoxins (or cardiotoxins; CTs) are toxins from cobra venom characterized by the three ... Cobra cytotoxins (CTs) belong to the three-fingered protein family. They are classified into S- and P-types, the latter ... Structurally different are cardiotoxins (or cytotoxins, СTs) from cobra venom. They are fully -structured molecules, ...
  http://www.ibch.ru/structure/groups/lbm/433
*  Análise transcriptômica das glândulas de veneno de Micrurus corallinus (cobra-coral)...
... cobra-coral), uma serpente da Família Elapidae bastante representada no Brasil e muito comum em áreas florestais tropicais,... ... To analyze the immunological response, recombinant proteins were produced in E. coli and used for ELISA coating to react with ... From the cDNA library of its venom glands, 1.438 Expressed Sequences Tags (ESTs) were generated and grouped into 611 clusters. ... Other neurotoxins 1), Atg5 (A2-type phospholipase). These five antigenic groups were used for DNA immunization. Then they were ...
  http://www.teses.usp.br/teses/disponiveis/41/41131/tde-02122008-143754/pt-br.php
*  Snake Venom Enzymes Proteins Substances Neurotoxic Effect Coagulants Biology Essay
Snake venom is adapted saliva that is formed by distinct glands of only certain species of snakes. The gland which secretes ... ... One of the major families of snake venom is the neurotoxins venoms; which means it's the venom which attacks the central ... Cobras, mambas, sea snakes, kraits and coral snakes are known to possess this venom. The king cobras (ophiophagus hannah) are ... The snake venoms that exist are categorized into several types such as hemotoxic venoms, neurotoxic venoms, cytotoxic venoms ...
  https://www.ukessays.com/essays/biology/snake-venom-enzymes-proteins-substances-neurotoxic-effect-coagulants-biology-essay.php
*  Лаборатория биомолекулярной ЯМР-спектроскопии - ИБХ РАН
While neurotoxins (NTs) - also TF proteins from snake venom - exert their effect through specific interactions with protein ... Protein Pept. Sci. 13 (6), 570-84 [+]. Cytotoxins (or cardiotoxins; CTs) are toxins from cobra venom characterized by the three ... Cytotoxins or cardiotoxins is a group of polycationic toxins from cobra venom belonging to the 'three-finger' protein ... One is disulfide-rich neurotoxins with a predominance of β-structure that specifically target protein receptors in neurons or ...
  http://www.ibch.ru/structure/groups/nmr/
*  venom facts, information, pictures | Encyclopedia.com articles about venom
Make research projects and school reports about venom easy with credible articles from our FREE, online encyclopedia and ... see also Globular Protein; Neurotoxin; Proteins; Toxicity.. Thomas A. Holme Bibliography. Agosta, William (2001). Thieves, ... Cobras, coral snakes, scorpions, and spiders produce neurotoxic venoms. The venom of the gaboon viper is both hemotoxic and ... ven·om·ous / ˈvenəməs/ • adj. (of animals, esp. snakes, or their parts) secreting venom; capable of injecting venom by means of ...
  http://www.encyclopedia.com/plants-and-animals/zoology-and-veterinary-medicine/zoology-general/venom
*  October, 2017 | Tim Underwood
The venom proteins may be a combination of neurotoxins, haemotoxins, cytotoxins and bungarotoxins along with other toxins. ... Venom has a hyalouronidase enzyme which assists in rapid diffusion of venom from the sufferer's body. Cobras and kraits possess ... The snake venom could be treated with the support of anti-venom. The doses of venom are raised in the future till the horse is ... Cobras, vipers and a few related ones use venom to trap or kill prey. Certain birds, mammals and a few snakes such as the ...
  http://booksbytimunderwood.com/2017/10/
*  The Vancouver Medical Association Bulletin: May, 1942 - UBC Library Open Collections
... so that what is now marketed is almost pure cobra neurotoxin. The preparation of Cobra venom has a rather interesting history. ... Roughly these are as follows: Proteins haemorrhagins cytotoxins mucus agglutinins haemotoxins enzymes precipitins neurotoxins ... I wish to report 78 cases who during the past two years have had Cobra venom for the relief of pain. COBRA VENOM Cases Good ... It so happens that the venom of the cobra is particularly rich in neurotoxin, which fraction is the desirable element in the ...
  https://open.library.ubc.ca/collections/historyofnursinginpacificcanada/vma/items/1.0214380
*  Cobratoxin - Wikipedia
α-Cobratoxin is a neurotoxin from the venom of certain Naja genus, including the Thailand cobra, the Indo-Chinese spitting ... The venom, produced by these snakes, is a mixture of proteins, carbohydrates, and other substances. The venom is only used when ... The cobratoxin of the Thailand cobra belongs to the neurotoxins. An important property of neurotoxins is that they are not ... "Inhibition of the nicotinic acetylcholine receptors by cobra venom α-neurotoxins: is there a perspective in lung cancer ...
  https://en.wikipedia.org/wiki/Cobratoxin
*  Directed Mutagenesis of Nicotinic Receptors to Investigate Receptor Function | IntechOpen
The α-neurotoxins from snake venoms are potent antagonists of nicotinic acetylcholine receptors. In mouse some of them are over ... 42 - Z Takacs, K Wilhelmsen, S Sorota, 2001Snake a-neurotoxin binding site on the Egyptian cobra (Naja haje) nicotinic ... 3) The mutated protein might adopt new properties that are unrelated to the natural protein. Hence, it is advisable always to ... Swapping internal protein domains may affect receptor assembly. Instead model proteins were used. They were left intact, but ...
  https://www.intechopen.com/books/genetic-manipulation-of-dna-and-protein-examples-from-current-research/directed-mutagenesis-of-nicotinic-receptors-to-investigate-receptor-function/
*  The QualityStocks Daily Newsletter
At the core of Nutra Pharma's intellectual property is a unique platform for extracting neurotoxins from Asian cobra venom and ... specialized receptor-binding proteins found in nature, especially those found in snake venom from the cobra. ReceptoPharm's R&D ...
  http://www.qualitystocks.net/newsletter/032116.html
*  Aliens Don't Like to Eat People That Smoke!
... venoms, neurotoxins, do exactly that. If you are bitten by a krait or a cobra, for example, and enough venom gets into the ... They are composed of 5 protein subunits which assemble like barrel staves around a central pore. ...When the ligand (ACh or ... blood, there will be enough of their neurotoxin in your body to shut down the diaphragm muscle expands your lungs. Without that ...
  http://www.sott.net/signs/anti-anti-smoking.htm
*  Ameliorating Adriamycin-Induced Chronic Kidney Disease in Rats by Orally Administrated Cardiotoxin from Naja naja atra Venom
"Cobra venom cardiotoxin (cytotoxin) isoforms and neurotoxin: comparative potency of protein kinase c inhibition and cancer cell ... S. Z. Wang, H. He, R. Han et al., "The protective effects of cobra venom from Naja naja atra on acute and chronic nephropathy ... "A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye ... G. L. Dai, J. K. He, Y. Xie, R. Han, Z. H. Qin, and L. J. Zhu, "Therapeutic potential of Naja naja atra venom in a rat model of ...
  https://www.hindawi.com/journals/ecam/2014/621756/ref/
*  Biochemical Identification of Membrane Receptors: Principles and Techniques | SpringerLink
Neurotoxin from venom of the cobra, Naja naja siamensis: Purification and radioactive labelling, J. Biol. Chem. 247: 3008-3013. ... Measurement of protein-binding phenomena by gel filtration, Biochim. Biophys. Acta 63: 530-532.PubMedGoogle Scholar ... The attractions of proteins for small molecules and ions, Ann. N. Y. Acad. Sci. 51: 660-672.Google Scholar ... Properties of glucagon-binding proteins isolated from liver plasma membranes, J. Biol. Chem. 249: 428-437.PubMedGoogle Scholar ...
  https://link.springer.com/chapter/10.1007/978-1-4684-3168-1_5
*  Protocols and Video Articles Authored by Christian Betzel
Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering ... cysteine-rich secretory proteins (CRISPs), venom nerve growth factors (VNGFs) and post-synaptic neurotoxins. Considerable ... We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms-that of the African cobra, N. m ... 104 proteins). Most of the proteins are homologues of known representatives of the respective protein families. The protein ...
  https://www.jove.com/author/Christian_Betzel
*  Naja christyi - Wikipedia
Venoms of the water cobras, were assayed for lethality, proteolytic activity and protein content. Naja annulata annulata and ... The LD50 of long-chain neurotoxins 2 from N. a. annulata and N. christyi venoms were 0.086 and 0.090 mg/kg, respectively. The ... christyi venom. The major lethal peaks (about 12% of total venom protein) were purified further with molecular sieve ... The venom of N. christyi is not well studied, but it is believed that the venom is dangerously neurotoxic, like that of most ...
  https://en.wikipedia.org/wiki/Naja_christyi