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*  Index of genetics articles - Wikipedia
Molecular biology Uptake signal sequence Uracil Uridine V-J joining Val Variable region Variance Variate Genetic diversity ... Conservative change Conserved sequence Constant region Constitutive gene Contig Contig map Contig maps Contiguous genes ... particle Transduction Transfection Transfer RNA Transferase Transform Transformation Transformer Transgenic Transgenic organism ... Clone bank Cloned DNA Cloning Cloning vector Coccus Code Code dictionary Coding strand Codominance Codon Codon usage bias aka ...
  https://en.wikipedia.org/wiki/Index_of_genetics_articles
*  Patent US7910370 - Methods of using BCL-2 for the therapeutic treatment and prevention of diseases - Google Patents
Such methods are known to one skilled in the art and can be found in Ausubel et al., Current Protocols in Molecular Biology ( ... major breakpoint region. Results were confirmed by DNA blot analysis of liver DNA isolated from F1 progeny of each transgenic ... Viral vectors commonly used for in vivo targeting and therapy procedures are retroviral vectors or DNA-based vectors. ... For example, the unregulated expression of many genes is now known to cause oncogenic transformation. These genes have ...
  http://www.google.com/patents/US7910370?dq=6650327
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Stem Cell Biology, Issue 77, Developmental Biology, Cellular Biology, Molecular Biology, Bioengineering, Biomedical Engineering ... Furthermore, because expression from electroporated vectors occurs within 6 hours 7, this method is more timely than transgenic ... A major approach in the field of mammalian cell biology is the manipulation of the expression of genes of interest in selected ... 12 modified the shRNA expression vector pSUPER5 by inserting a TO in the promoter region, which enabled them to generate stable ...
  https://www.jove.com/visualize/abstract/24223709/a-novel-piggybac-transposon-inducible-expression-system-identifies
*  US6617112B2 - Methods for gene array analysis of nuclear runoff transcripts - Google Patents
As used herein "suicide vector" means a vector without an origin of replication or a vector with an origin of replication that ... "Transcriptional Regulation of the Arabidopsis thaliana Chalcone Synthase Gene, Molecular and Cellular Biology, Vol. 8, No. 5, ... promoter or partial promoter and a desired protein encoding region. The recombinant vector of this invention may be any vector ... As used herein "transgenic cell" means a cell derived or regenerated from a transformed cell or derived from a transgenic cell ...
  https://patents.google.com/patent/US6617112B2/en
*  Plus it
Advances in plant molecular biology have greatly facilitated efforts to isolate plant genes associated with agronomically ... Arrows show coloration of the epidermal region. Bar = 1 cm. (C) PPO enzyme activity in field-grown wild type (WT), transgenic ... Schematic representation of LifeSupport vectors. A, Vectors used for two-strain approaches. B, Vectors used for the one-strain ... Rather than eliminating plants containing backbone, as is the case with the barnase suicide gene (Hanson et al., 1999), we ...
  http://www.plantphysiol.org/content/135/1/421
*  Method for treating a metastatic carcinoma using a conditionally lethal gene - Patent # 5997859 - PatentGenius
... the animal a viral vector such as that described above, in order to inhibit or destroy the pathogenic agent. ... The present invention provides recombinant viral vectors carrying a vector construct which directs the expression of a gene ... Molecular and Cellular Biology 9: 3517-3523, 1989... van Assendelft et al., "The .beta.-Globin Dominant Control Region ... Alternatively, the cytotoxic genes, gene products,vector constructs or viral vectors of the present invention may also be ...
  http://www.patentgenius.com/patent/5997859.html
*  Best binary option sites
The most complex diseases involve many genes, and transgenic models would be difficult to create. Perhaps the main best binary ... Courtesy of Martin Guthold and Carlos Bustamante, Institute of Molecular Biology and HHMI, University of Oregon. ... seelisting best binary option sites vectors (I)), the entire coding region was removed. l3y using Equations (3. Best binary ... This augmentation ofthe immune response with cytokine productmioanyalso be synergistically enhancedby the additionof suicide ...
  http://4gamers-market.ru/best-binary-option-sites-1.html
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Plant Biology, Issue 77, Genetics, Molecular Biology, Cellular Biology, Virology, Microbiology, Bioengineering, Plant Viruses, ... Explanation is given for how key refractory genes, those genes conferring resistance to vector pathogens, are identified in the ... Transgenic mice carrying site-specific genome modifications (knockout, knock-in) are of vital importance for dissecting complex ... peptide fused to modified IgG4 Fc region) and CD64 (Fc-γ receptor 1) for the loading of monoclonal antibodies (mAb)12. In this ...
  https://www.jove.com/visualize/abstract/22096482/an-efficient-vector-system-to-modify-cells-genetically
*  Patent US6783977 - Internal ribosome entry site and vector containing same - Google Patents
The invention also concerns a vector comprising said nucleotide sequence, a viral particle generated from this vector, a cell ... The invention further concerns the use of a vector, a viral particle or a pharmaceutical composition for transfecting or ... as internal ribosome entry site or as element enabling or improving retrovirus vector packaging. ... comprising this vector or infected by the viral particle, their therapeutic use and a pharmaceutical composition containing ...
  http://www.google.ca/patents/US6783977
*  Overview of gene therapy clinical progress including cancer treatment with gene-modified T cells
Under these circumstances, genotoxicity may occur, in which the integrating vector disrupts the function of critical genes, ... and with advances in our understanding of the molecular and cell biology of genetic diseases and of cancer, unequivocal ... Preclinical studies have shown that infusion of αβ TCR transgenic T cells can eradicate tumors in vivo.20,21 Recently, Morgan ... 6. Fillat C, Carrió M, Cascante A, Sangro B. Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/ ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2929387/
*  Patente US8093043 - β-TrCP1, β-TrCP2 and RSK1 or RSK2 inhibitors and methods for sensitizing ... - Google Patentes
Vector constructs may be produced using conventional molecular biology and recombinant DNA techniques within the skill of the ... Kollias et al., Regulated expression of Human Ag-, b-, and Hybrid gb-Globin Genes in Transgenic Mice: Manipulation of the ... Apoptosis is also called programmed cell death or cell suicide.. As used herein, apoptosis, cell suicide, and programmed cell ... Human β-TrCP1 is a variant that contains an additional 108 nt fragment within the coding region, as compared to human variant 2 ...
  http://www.google.es/patents/US8093043?hl=es&dq=flatulence
*  ASMscience | Sleeping Beauty Transpos
Sleeping beauty transposition: biology and applications for molecular therapy. Mol Ther 9 : 147-156.[PubMed] [CrossRef] ... Gene transfer vector system based on SB. The transposase coding region can be replaced by a gene of interest (yellow box) ... Retrotransposon suicide: formation of Ty1 circles and autointegration via a central DNA flap. J Virol 80 : 11920-11934.[PubMed] ... Transgenic tomato lines containing Ds elements at defined genomic positions as tools for targeted transposon tagging. Mol Gen ...
  http://www.asmscience.org/content/book/10.1128/9781555819217.chap38
*  Selective gene silencing by viral delivery of short hairpin RNA | Virology Journal | Full Text
... therefore all viral genes in the vector genome can be replaced with foreign sequences. Vector particles are produced by ... Recent advances in molecular biology have allowed the design of several genetically modified viruses, such as Adenovirus [104, ... Here, the U3 region of the UTR is deleted, and a heterologous promoter (such as CMV) ensures transcription of the entire vector ... Many reports describe replicating MLVs for gene therapy using inserted suicide genes [126]. We pioneered replicating MLVs as ...
  https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-7-248
*  First Meeting of the Oligonucleotide Therapeutics Society | The New York Academy of Sciences
Using the building blocks of RNA to interfere with the operation of specific genes could produce safe, effective medicines and ... MRC Laboratory of Molecular Biology. email , web site , publications. Martin E. Gleave, MD, FRCSC, FACS. The Prostate Center at ... Ribozymes have an advantage over ODNs in that ribozyme genes can be delivered to cells with plasmid or viral vectors, and ... Antisense-assisted cell suicide. For oligonucleotide therapeutics to become full-fledged templates for new drug development, ...
  https://www.nyas.org/ebriefings/first-meeting-of-the-oligonucleotide-therapeutics-society/
*  A Versatile and Reliable Two-Component System for Tissue-Specific Gene Induction in Arabidopsis | Plant Physiology
In RA Meyers, ed, Encyclopedia of Molecular Cell Biology and Molecular Medicine. Wiley-VCH, Weinheim, Germany, pp 245-282. ... Vectors pMDC160, pMDC220, and pMDC221 contain a Nos promoter to drive the expression of the BAR- or hygromycin-resistance genes ... An attR1-Cmr-ccdB-attR2 integration region from the Gateway cloning system (Invitrogen) was placed downstream of a promoter ... Mizukami Y, Ma H (1992) Ectopic expression of the floral homeotic gene AGAMOUS in transgenic Arabidopsis plants alters floral ...
  http://www.plantphysiol.org/content/141/4/1194.full
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Molecular Biology, Issue 78, Cellular Biology, Biochemistry, Biomedical Engineering, Stem Cell Biology, Cancer Biology, ... Cellular Biology, Issue 96, Anastasis, apoptosis, apoptotic bodies, caspase, cell death, cell shrinkage, cell suicide, ... A transgenic mouse line (M83) over-expressing the human A53T αS and spontaneously developing a dramatic clinical phenotype ... An urgent need exists to test the contribution of new genes to the pathogenesis and progression of human glioblastomas (GBM), ...
  https://www.jove.com/visualize/abstract/25993328/immunohistochemical-assessment-phosphorylated-mtorc1-pathway-proteins
*  DiVA - Search result
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Cell and Molecular Biology, Molecular ... We highlighted two genes in the inverted region; HSD17B2 that affects metabolism of testosterone and MC1R that has a key role ... The aphid reduces yield and can act as a vector of barley yellow dwarf virus. R. padi does not give visible symptoms, but heavy ... Accusations of fraud generated a great scandal, ending with Kammerer's suicide. Controversy reignited in the 1970s, when ...
  http://www.diva-portal.org/smash/resultList.jsf?searchType=SUBJECT&language=en&onlyFullText=false&af=%5B%5D&aq=%5B%5B%7B%22categoryId%22%3A%2211727%22%7D%5D%5D
*  Programmed cell death - Wikipedia
A molecular characteristic of metastatic cells is their altered expression of several apoptotic genes. Anoikis Apoptosis- ... As such, the cell suicide mechanism is now crucial to all of our lives. The BCR-ABL oncogene has been found to be involved in ... doi:10.1016/s0361-9230(01)00639-6. Rondi-Reig, L (2001). "Transgenic mice with neuronal overexpression of bcl-2 gene present ... ISBN 978-0-87969-888-1. D. Bowen, Ivor (1993). Cell Biology International 17. Great Britain: Portland Press. pp. 365-380. ISSN ...
  https://en.wikipedia.org/wiki/Programmed_cell_death
*  Protocols and Video Articles Authored by Elizabeth Jones (Translated to Korean)
The Culture of Mouse Embryonic Stem Cells and Formation of Embryoid Bodies Methods in Molecular Biology (Clifton, N.J.). 2010 ... elements within the IL-10 family locus and present data herein on a conserved 40-kb region between the IL-19 and IL-10 genes. ... A challenge in preventing suicide is to provide a person hope so that she or he can see that suicide is not the only way out. ... We have used ES cells carrying a gene trap vector insertion (I.114) into an ankyrin repeat-containing gene (Gtar) that we have ...
  https://www.jove.com/author/Elizabeth_Jones?language=Korean
*  Faculty Briefs - 2009
2009). "P27(Kip1) inhibits cyclin d-cyclin-dependent kinase 4 by two independent modes." Molecular and Cellular Biology 29(4): ... 2009). "Transgenic mice with increased activity of the antioxidant enzyme cuzn-sod have improved survival in Lps-induced septic ... Kubie, J.L., A.A. Fenton (2009). "Heading-vector navigation based on head-direction cells and path integration." Hippocampus 19 ... Cheng, Z., K. Saito, A.V. Pisarev (2009). "Structural insights into eRF3 and stop codon recognition by eRF1." Genes and ...
  http://library.downstate.edu/resources/facultybriefs2009.htm
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Plant Biology, Issue 77, Genetics, Molecular Biology, Cellular Biology, Virology, Microbiology, Bioengineering, Plant Viruses, ... DNA Vector-based RNA Interference to Study Gene Function in Cancer. Authors: Daniel B. Stovall, Meimei Wan, Qiang Zhang, ... PiggyBac can be used to modify human T cells with a variety of genes of interest. Although we have used piggyBac to direct T ... It effectively transduces naive mouse T cells if they express a transgenic Coxsackie adenovirus receptor (CAR). Importantly, ...
  https://www.jove.com/visualize/abstract/23555950/an-efficient-low-cost-method-for-gene-transfer-to-t-lymphocytes
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Developmental Biology, Issue 100, Stem cell biology, cellular biology, molecular biology, induced pluripotent stem cells, ... Cellular Biology, Issue 96, Anastasis, apoptosis, apoptotic bodies, caspase, cell death, cell shrinkage, cell suicide, ... Additionally, this system can be used to examine the functions of genes through the use of siRNAs as well as of chemical ... Induced pluripotent stem cells (iPSCs) are reprogrammed from human fibroblasts using episomal vectors. Colonies of iPSCs can be ...
  https://www.jove.com/visualize/abstract/25693182/cardiac-telocytes-fibroblasts-primary-culture-different-morphologies
*  Magnetic Resonance Reporter Gene Imaging
Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev. 2003;17:545-80 ... Molecular imaging encompasses the fields of chemistry, biology, physics, and medicine, and brings experts in these scientific ... Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission ... pRev-tTA-OFF-IN vector). Cells were then transfected to express TET-EGFP-HA-ferritin using a bidirectional vector (pBI-EGFP-HA- ...
  http://www.thno.org/v02p0403.htm
*  Volume 8 - GTMB: Gene Therapy & Molecular Biology
The Journal of Gene Therapy Molecular Biology provides , comprehensive and broad coverage in all areas of the field. Free & ... Although these vectors are very efficient in transferring foreign genes into a variety of cell types, their use as gene ... minimal vectors and contain the central polypurine track (cPPT) region and the Woodchuck Hepatitis Virus posttranscriptional ... Lipid-DNA complexes may be useful for suicide gene therapy of oral squamous cell carcinoma (OSCC) cells since a high percentage ...
  http://gtmb.org/?vol=8
*  Frontiers | Expanding the Therapeutic Window for CAR T Cell Therapy in Solid Tumors: The Knowns and Unknowns of CAR T Cell...
There remain a lot of unknowns on tumor biology, the TME and CAR T cell biology. Fortunately, powerful tools to address these ... Each subunit contains a variable region domain (V) and a constant region domain (C), which is followed by a transmembrane ... Molecular architecture of the alphabeta T cell receptor-CD3 complex. Proc Natl Acad Sci USA. (2014) 111:17576-81. doi: 10.1073/ ... Equipping CAR T cells with a suicide system, such as inducible caspase-9 (iCas9) (97, 98) or co-expression of truncated EGFR ( ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2018.02486/full