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*  Exercise and the Nitric Oxide Vasodilator System | SpringerLink
The endothelium produces numerous vasodilator and vasoconstrictor compounds that regulate vascu ... A comparative study of four anti-hypertensive agents on endothelial function in patients with coronary disease. J Am Coll ... The endothelium produces numerous vasodilator and vasoconstrictor compounds that regulate vascular tone; the vasodilator, ... Vasodilator responses of coronary resistance arteries of exercise-trained pigs. Circulation 1994; 89: 2308-14PubMedCrossRef ...
  https://link.springer.com/article/10.2165/00007256-200333140-00001
*  Nitrolingual nitroglycerin spray - Things You Didn't Know
... low blood pressure and stroke volume all have the potential for serious hypotension to be caused by the use of the agent. ... It is a vasodilator so that low blood volume, fever and vasodilation, ... It is a vasodilator so that low blood volume, fever and vasodilation, low blood pressure and stroke volume all have the ... Nitrolingual is a nitrate based agent which is a kind of chest pain drug (cardiovascular drug). ...Read more ...
  https://www.healthtap.com/topics/nitrolingual-nitroglycerin-spray
*  Restrictive cardiomyopathy - Wikipedia
Vasodilators are also typically ineffective because systolic function is usually preserved in cases of RCM. Heart failure ... Digoxin, calcium channel blocking drugs and beta-adrenergic blocking agents provide little benefit, except in the subgroup of ... "Worsening of congestive heart failure in amyloid heart disease treated by calcium channel-blocking agents". American Journal of ...
  https://en.wikipedia.org/wiki/Restrictive_cardiomyopathy
*  Diazoxide - Wikipedia
In the United States, this agent is only available in the oral form and is typically given in hospital settings. Diazoxide is ... van Hamersvelt HW, Kloke HJ, de Jong DJ, Koene RA, Huysmans FT (August 1996). "Oedema formation with the vasodilators ... doi:10.1016/0006-2952(89)90327-4. Doyle, Máire E.; Egan, Josephine M. (2003-03-01). "Pharmacological Agents That Directly ... used as a vasodilator in the treatment of acute hypertension or malignant hypertension. Diazoxide also inhibits the secretion ...
  https://en.wikipedia.org/wiki/Diazoxide
*  Pildralazine - Wikipedia
C. R Ganellin; D. J Triggle; F.. Macdonald (1997). Dictionary of pharmacological agents. CRC Press. p. 1603. ISBN 978-0-412- ... Pildralazine (Atensil), also known as propyldazine or propildazine, is an antihypertensive and vasodilator. ...
  https://en.wikipedia.org/wiki/Pildralazine
*  Nitroglycerin - Wikipedia
For over 130 years, nitroglycerin has been used medically as a potent vasodilator (dilation of the vascular system) to treat ... The percentage varies with the desensitizing agent used.) Desensitization requires extra effort to reconstitute the "pure" ... These agents all exert their effect by being converted to nitric oxide in the body by mitochondrial aldehyde dehydrogenase, and ... of ischemic heart disease caused by inadequate flow of blood and oxygen to the heart and as a potent antihypertensive agent. ...
  https://en.wikipedia.org/wiki/Nitroglycerin
*  Treprostinil - Wikipedia
PG-X, which later would become known as prostacyclin, was 30 times more potent than any other known anti-aggregatory agent.[ ... Since treprostinil is a vasodilator, its antihypertensive effect may be compounded by other medications that affect the blood ... is a vasodilator that is used for the treatment of pulmonary arterial hypertension. Treprostinil is a synthetic analog of ... pressure, including calcium channel blockers, diuretics, and other vasodilating agents. Because of treprostinil's inhibiting ...
  https://en.wikipedia.org/wiki/Treprostinil
*  Alpha-1 blocker - Wikipedia
Prazosin was synthesized in 1974 when Constantin and Hess were trying to discover a vasodilator which had a minimal effect on ... Alpha-1 blockers (also called alpha-adrenergic blocking agents) constitute a variety of drugs that block alpha-1-adrenergic ... Because these medications may cause orthostatic hypotension, as well as low blood pressure in general, these agents may ... Since alpha-1 blockers may cause orthostatic hypotension, co-administration with antihypertensives and vasodilators must be ...
  https://en.wikipedia.org/wiki/Alpha-1_blocker
*  Molsidomine - Wikipedia
A mesoionic sydnone is active as an antianginal agent. Its synthesis starts by reacting 1-aminomorpholine with formaldehyde and ... Nitric oxide Nitrate (pharmacology) Vasodilator Rosenkranz, B.; Winkelmann, B. R.; Parnham, M. J. (1996). "Clinical ...
  https://en.wikipedia.org/wiki/Molsidomine
*  Blood vessel - Wikipedia
The most prominent vasodilator is nitric oxide (termed endothelium-derived relaxing factor for this reason). The blood pressure ... It is regulated by vasoconstrictors (agents that cause vasoconstriction). These include paracrine factors (e.g. prostaglandins ...
  https://en.wikipedia.org/wiki/Blood_vessel
*  Aortic dissection - Wikipedia
Vasodilators such as sodium nitroprusside can be considered for people with ongoing high blood pressure, but they should never ... In acute dissection, fast-acting agents which can be given intravenously and have doses that are easier to adjust (such as ... The calcium channel blockers typically used are verapamil and diltiazem, because of their combined vasodilator and negative ... persistent hypertension on the maximum doses of three different classes of antihypertensive agents), an involvement of the ...
  https://en.wikipedia.org/wiki/Aortic_dissection
*  Angiotensin-converting enzyme - Wikipedia
Therefore, ACE can be inhibited by metal-chelating agents. The E384 residue was found to have a dual function. First it acts as ... Thus, the same enzyme (ACE) that generates a vasoconstrictor (ANG II) also disposes of vasodilators (bradykinin). ACE is a zinc ... ACE is also part of the kinin-kallikrein system where it degrades bradykinin, a potent vasodilator, and other vasoactive ... are ACE inhibitors and angiotensin II type 1 receptor antagonists potential doping agents?". Sports Medicine. 38 (12): 1065-79 ...
  https://en.wikipedia.org/wiki/Angiotensin-converting_enzyme
*  Niceritrol - Wikipedia
Niceritrol is a niacin derivative used as a hypolipidemic agent. It is an ester of pentaerythritol and nicotinic acid, has ... Niceritrol has been used as a lipid regulating drug in hyperlipidaemias and as a vasodilator in the treatment of peripheral ...
  https://en.wikipedia.org/wiki/Niceritrol
*  Nitrite - Wikipedia
Sodium nitrite is used for the curing of meat because it prevents bacterial growth and, as it is a reducing agent (opposite of ... Nitrite is also important in biochemistry as a source of the potent vasodilator nitric oxide. In organic chemistry the NO− 2 ... Nitrite can be oxidized or reduced, with the product somewhat dependent on the oxidizing/reducing agent and its strength. The ... Addition of acid to a solution of a nitrite in the presence of a reducing agent, such as iron(II), is a way to make nitric ...
  https://en.wikipedia.org/wiki/Nitrite
*  Quazinone - Wikipedia
Quazinone (Dozonone) is a cardiotonic and vasodilator drug which was developed and marketed in the 1980s for the treatment of ... Phosphodiesterase inhibitor David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN ... June 1985). "RO13-6438, a new inotrope-vasodilator: systemic and coronary hemodynamic effects in congestive heart failure". The ... a novel positive inotropic agent with vasodilating properties". Journal of Cardiovascular Pharmacology. 6 (3): 511-9. doi: ...
  https://en.wikipedia.org/wiki/Quazinone
*  Vasomotor - Wikipedia
Some vasoactive chemicals such as vasodilator acetylcholine are known for causing reduced/increased blood flow in the tumours ... to the tumour cells can cause the cells to be radio-resistant and resulted in reduced accessibility to chemotherapeutic agents ... More specifically, it can refer to vasodilator action and vasoconstrictor action. Sympathetic nerve fibers travel around the ... Endothelin, and angiotensin are the vasocontrictors of smooth muscles while nitric oxide and prostacyclin are vasodilators of ...
  https://en.wikipedia.org/wiki/Vasomotor
*  Isoquinoline - Wikipedia
vasodilators, a well-known example, papaverine, shown below. Bisbenzylisoquinolinium compounds are compounds similar in ... antifungal agents, such as 2,2′-hexadecamethylenediisoquinolinium dichloride, which is also used as a topical antiseptic. This ... antihypertension agents, such as quinapril, quinapirilat, and debrisoquine (all derived from 1,2,3,4-tetrahydroisoquinoline). ...
  https://en.wikipedia.org/wiki/Isoquinoline
*  Salvador Moncada - Wikipedia
This finding elucidated the mechanism by which these drugs act as analgesic, antipyretic, and anti-inflammatory agents and also ... he led the team that discovered the enzyme thromboxane synthase and the vasodilator prostacyclin. This work contributed to the ...
  https://en.wikipedia.org/wiki/Salvador_Moncada
*  Hyperaemia - Wikipedia
It is widely thought that active hyperaemia is mediated by the increased synthesis and/or release of vasodilatory agents during ... Recent research has suggested that the locally produced vasodilators may be acting in a redundant manner, in which the ... Some of the putative vasodilatory agents (associated with metabolism) include, but are not limited to: Carbon dioxide (CO2), ... It is thought that vasodilators (released from active muscle fibers) can stimulate a local capillary endothelial cells which, ...
  https://en.wikipedia.org/wiki/Hyperaemia
*  Pharmaceutical industry - Wikipedia
Agents. 31 (3): 189-92. doi:10.1016/j.ijantimicag.2007.11.010. PMID 18248798. Abraham EP (1987). "Cephalosporins 1945-1986". ... In 1952 researchers at Ciba discovered the first orally available vasodilator, hydralazine. A major shortcoming of hydralazine ... Approximately 400 tons of these agents are manufactured each year; this is enough to put approximately 9,000,000 people to ... Lv J, Perkovic V, Foote CV, Craig ME, Craig JC, Strippoli GF (2012). "Antihypertensive agents for preventing diabetic kidney ...
  https://en.wikipedia.org/wiki/Pharmaceutical_industry
*  Calcium channel blocker - Wikipedia
The negative chronotropic effects of CCBs make them a commonly used class of agents in individuals with atrial fibrillation or ... By having both cardiac depressant and vasodilator actions, benzothiazepines are able to reduce arterial pressure without ... For severe overdoses, treatment usually includes close monitoring of vital signs and the addition of vasopressive agents and ... Diltiazem (Cardizem) (also used experimentally to prevent migraine) While most of the agents listed above are relatively ...
  https://en.wikipedia.org/wiki/Calcium_channel_blocker
*  Raynaud syndrome - Wikipedia
Sympatholytic agents, such as the alpha-adrenergic blocker prazosin, may provide temporary relief. Losartan can, and topical ... Vasodilators - calcium channel blockers, such as the dihydropyridines nifedipine or amlodipine, preferably slow release ... Peoples whose RP is secondary to erythromelalgia often cannot use vasodilators for therapy as they trigger 'flares' causing the ... Nifedipine, a calcium channel blocker and vasodilator, was recommended to increase blood flow to the extremities and noticeably ...
  https://en.wikipedia.org/wiki/Raynaud_syndrome
*  Arterial embolism - Wikipedia
Antithrombotic agents may be administered directly onto the clot in the vessel using a flexible catheter (intra-arterial ... can dissolve clots Painkillers given intravenously Vasodilators to relax and dilate blood vessels. Appropriate drug treatments ...
  https://en.wikipedia.org/wiki/Arterial_embolism
*  Regadenoson - Wikipedia
The selective nature of the drug makes it preferable to other stress agents such as adenosine, which are less selective and ... Regadenoson (CVT-3146, Lexiscan) is an A2A adenosine receptor agonist that is a coronary vasodilator that is commonly used in ...
  https://en.wikipedia.org/wiki/Regadenoson
*  Fostedil - Wikipedia
Fostedil (A-53,986, KB-944) is a vasodilator acting as a calcium channel blocker which was under development for the treatment ... Ibrolipim Calcium channel blocker David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC ... Morita T, Yoshino K, Kanazawa T, Ito K, Nose T (1982). "Vasodilator action of KB-944, a new calcium antagonist". Arzneimittel- ... Morita T, Kanazawa T, Ito K, Nose T (1982). "Vasodilator mechanism of KB-944, a new calcium antagonist". Arzneimittel-Forschung ...
  https://en.wikipedia.org/wiki/Fostedil