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*  Molecules | Free Full-Text | Role of O-Acetylation in the Immunogenicity of Bacterial Polysaccharide Vaccines
The structures of the bacterial capsular polysaccharide (CPS) antigens, extracted and purified from microbial cultures and ... While these groups are often considered important for the structural identity of the polysaccharides, they play a major role in ... has been dramatically reduced over the last 25 years through the use of glycoconjugate vaccines. ... the functional immune response to some vaccines such as meningococcal serogroup A and Salmonella typhi Vi, but do not seem to ...
  http://www.mdpi.com/1420-3049/23/6/1340
*  MRSA Infection Holistic Treatment - Ormed Medical Exchange
Bacterial Polysaccharide Vaccines Mon, 27 Mar 2017 , Vademecum Capsulated bacteria, Gram-positive or Gram-negative, cause a ... Bacterial pneumonia Last Updated on Wed, 18 Sep 2013 , Operating Room The bacteria that are most frequently found to cause ... Bacterial interactions Last Updated on Wed, 06 Apr 2016 , Cosmetic Microbiology Epithelial intestinal cells being covered with ... In vaccine studies, such viruses have been shown to retain their protective efficacy compared with their wild-type, replication ...
  https://www.ormedmedical.us/staphylococcus-aureus.html
*  Immunization of Health-Care Workers: Recommendations of the Advisory Committee on Immunization Practices (ACIP) and the...
Additional vaccines, particularly bacterial polysaccharide vaccines (i.e., Haemophilus influenzae type b {Hib} vaccine, ... after MMR vaccine, or 3 weeks after varicella vaccine. Delay administration of MMR vaccine for ,=3 months and varicella vaccine ... vaccine is used, and every 2 years if the capsular polysaccharide vaccine is used. Live-attenuated Ty21a vaccine should not be ... The safety of the vaccine in polysaccharide and by route specified HCWs in the United States. pregnant women has not vaccine ( ...
  https://www.cdc.gov/mmwr/preview/mmwrhtml/00050577.htm
*  Recommendations of the Advisory Committee on Immunization Practices (ACIP): Use of Vaccines and Immune Globulins in Persons ...
... and additional vaccines, particularly bacterial polysaccharide vaccines {Haemophilus influenzae type b (Hib), pneumococcal and ... Some antigens, particularly bacterial polysaccharide vaccines, are recommended for such patients. Frequently, the immune ... see discussion under Pneumococcal vaccine). Quadrivalent meningococcal polysaccharide vaccine also should be administered to ... vaccines or higher doses of vaccines but that do not contraindicate use of any particular vaccine. ...
  https://www.cdc.gov/mmwr/preview/mmwrhtml/00023141.htm
*  Selective Antibody Deficiency - The Clinical Advisor
"Evaluating children with respiratory tract infections: the role of immunization with bacterial polysaccharide vaccine". Pediatr ... Because the B cell defect is limited to polysaccharide antigens, immunization with conjugated vaccines such as H flu vaccine ... By conjugating polysaccharide antigens with proteins, as in the heptavalent and 13-valent pneumococcal polysaccharide vaccines ... Bacterial cell wall polysaccharides are classified as T independent antigens, meaning they can stimulate B cells directly and ...
  http://www.clinicaladvisor.com/pediatrics/selective-antibody-deficiency/article/623992/
*  Negative immunomodulation by parasitic infections in the human response to vaccines
The most affected vaccines are Bacillus Calmette-Guérin and bacterial polysaccharide vaccines. Malaria is the infection most ... We also identified the parasites most associated with immunomodulation of vaccine responses and those vaccines most affected. ... infections is associated with modulation of the immune system and changes in the response to bacterial and viral vaccines. The ... In addition, articles evaluating the effect of chemoprophylaxis for malaria on the immune response against vaccines were ...
  https://jidc.org/index.php/journal/gateway/plugin/WebFeedGatewayPlugin/rss2
*  What Is and What Should Always Have Been: Long-Lived Plasma Cells Induced by T Cell-Independent Antigens | The Journal of...
1A). As a consequence, few polysaccharide vaccines consisting of bacterial capsule Ags are currently available. One noteworthy ... Indeed, whereas vaccines to T cell-dependent Ags are more likely to be long-lasting, those against certain T cell-independent ... For responses to polysaccharides, classically referred to as type 2 T cell-independent Ags, Taillardet et al. (38) demonstrated ... Duration of humoral immunity to common viral and vaccine antigens. N. Engl. J. Med. 357: 1903-1915. ...
  http://www.jimmunol.org/content/190/12/5913
*  RCSB PDB - 5JOP: Crystal structure of anti-glycan antibody Fab14.22 in complex with Streptococcus pneumoniae serotype 14...
Carbohydrate conjugate vaccines achieve this by coupling bacterial polysaccharides to a carrier protein that recruits ... Vaccines targeting glycan structures at the surface of pathogenic microbes must overcome the inherent T cell-independent nature ... Vaccines targeting glycan structures at the surface of pathogenic microbes must overcome the inherent T cell-independent nature ... To produce the next generation of more efficacious conjugate vaccines, we have explored a synthetic design aimed at focusing ...
  https://www.rcsb.org/structure/5JOP
*  Meet Our Authors - February Special Dendrimer Issue 2012 - NJC Blog
René and his collaborators have contributed to the commercialization of two bacterial polysaccharide-based vaccines against ... Glycodendrimers as functional antigens and antitumor vaccines by Tze Chieh Shiao and René Roy; New J. Chem., 2012, 36, 324-339 ... he highlights recent developments in the chemical synthesis of carbohydrate-associated cancer vaccines that include the use of ...
  http://blogs.rsc.org/nj/2012/02/14/meet-our-authors-%E2%80%93-february-special-dendrimer-issue-2012/?doing_wp_cron=1516269519.7133929729461669921875
*  Hib vaccine - Wikipedia
Finn, Adam (2004-01-01). "Bacterial polysaccharide-protein conjugate vaccines". British Medical Bulletin. 70 (1): 1-14. doi: ... The shortcomings of the polysaccharide vaccine led to the production of the Hib polysaccharide-protein conjugate vaccine. ... The first Hib vaccine licensed was a pure polysaccharide vaccine, first marketed in the US in 1985. Similar to other ... All Hib vaccines that are currently used are conjugate vaccine. An initial Hib vaccine was developed in 1977 which was replaced ...
  https://en.wikipedia.org/wiki/Hib_vaccine
*  George Siber bibliography - Wikipedia
... diphtheria toxoid conjugate vaccine given with or without bacterial polysaccharide immune globulin (BPIG) in Navajo infants. ... "Comparison of pneumococcal conjugate polysaccharide and free polysaccharide vaccines in elderly adults: conjugate vaccine ... diphtheria toxoid conjugate vaccine given with or without Bacterial Polysaccharide Immune Globulin (BPIG). Interscience ... "Antibody response to pretreatment immunization and post-treatment boosting with bacterial polysaccharide vaccines in patients ...
  https://en.wikipedia.org/wiki/George_Siber_bibliography
*  Pneumococcal Polysaccharide Vaccine (23-Valent) (Professional Patient Advice) - Drugs.com
Professional guide for Pneumococcal Polysaccharide Vaccine (23-Valent). Includes: pharmacology, pharmacokinetics, ... Vaccine, Inactivated (Bacterial). Pharmacology. Pneumococcal polysaccharide polyvalent is an inactive bacterial vaccine that ... Pneumococcal vaccine-naive or vaccination status unknown: Administer PCV13 followed by pneumococcal polysaccharide vaccine ( ... Zoster Vaccine (Live/Attenuated): Pneumococcal Polysaccharide Vaccine (23-Valent) may diminish the therapeutic effect of Zoster ...
  https://www.drugs.com/ppa/pneumococcal-polysaccharide-vaccine-23-valent.html
*  Immunogenicity and mechanisms of action of PnuBioVax, a multi-antigen serotype-independent prophylactic vaccine against...
Whilst the capsule antigen is the target of the polysaccharide vaccines, bacterial proteins can also act as targets for the ... Sera from PBV immunised rabbits contained high levels of IgG antibodies to the PBV vaccine, and pneumococcal antigens PspA, Ply ... Streptococcus pneumoniae has multiple protein antigens on the surface in addition to the serotype specific polysaccharide ... The PBV sera supported killing of the vaccine strain TIGR4 in an opsonophagocytic killing assay and heterologous strains 6B, ...
  https://www.synbiosis.com/technical-paper/immunogenicity-and-mechanisms-of-action-of-pnubiovax-a-multi-antigen-serotype-independent-prophylactic-vaccine-against-infection-with-streptococcus-pneumoniae/
*  Pathogenic Bacterial Sensors Based on Carbohydrates as Sensing Elements | Springer for Research & Development
Lee CJ (1987) Bacterial Capsular Polysaccharides - Biochemistry, Immunity and Vaccine. Mol Immunol 24:1005-1019Google Scholar ... Sood RK, Fattom A, Pavliak V and Naso RB (1996) Capsular polysaccharide-protein conjugate vaccines. Drug Discov Today 1:381-387 ... Moxon ER and Kroll JS (1990) The Role of Bacterial Polysaccharide Capsules as Virulence Factors. Curr Top Microbiol Immunol 150 ... Weintraub A (2003) Immunology of bacterial polysaccharide antigens. Carbohydr Res 338:2539-2547Google Scholar ...
  https://rd.springer.com/chapter/10.1007/978-0-387-75113-9_24
*  Practical Fragments: May 2015
For Streptococcus pneumoniae, there are a numbers of vaccines on the market. These vaccines are bacterial polysaccharides ... transport across the bacterial cell membrane. (See there's always a metal involved in cool biology.) This makes PsaA a good ...
  http://practicalfragments.blogspot.com/2015/05/
*  Science & Research (Biologics)
Vaccines Research. Bacterial Polysaccharides, Enteric & Sexually Transmitted Diseases, Mycobacterial Diseases & Cellular ... General Biologics Research Allergenics Research Blood Research Tissue & Advanced Therapies Research Tissue Research Vaccines ... and vaccines, to name a few. This research broadens FDA's knowledge of fundamental biological processes and provides a robust ...
  https://www.fda.gov/biologicsbloodvaccines/scienceresearch/default.htm
*  Rabies and Related Lyssaviruses | SpringerLink
Rabies is a significant neglected vaccine-preventable disease that is global in distribution. Multiple biologics are utilized ... Recombinant plants provide a new approach to the production of bacterial polysaccharide for vaccines. PLoS ONE 9(2):e88144 ... Anti-foot-and-mouth vaccines combined with other bacterial or viral vaccines. Dev Biol Stand 35:409-428PubMedGoogle Scholar ... Yang DK, Kim HH, Lee KW, Song JY (2013) The present and future of rabies vaccine in animals. Clin Exp Vaccine Res 2(1):19-25 ...
  https://link.springer.com/chapter/10.1007%2F978-3-319-90137-4_3
*  Preventing Pneumococcal Disease Among Infants and Young Children
PNEUMOCOCCAL CONJUGATE VACCINE Advantages of Pneumococcal Conjugate Vaccine: Immunologic Theory Bacterial polysaccharides, ... conjugate vaccine followed, ,2 months later, by 23-valent polysaccharide vaccine. Conjugate vaccine has not been studied ... In February 2000, a 7-valent pneumococcal polysaccharide-protein conjugate vaccine (Prevnar, marketed by Wyeth Lederle Vaccines ... Vaccine Composition The 7-valent pneumococcal conjugate vaccine (Prevnar) includes seven purified capsular polysaccharides of S ...
  https://www.cdc.gov/MMWR/preview/MMWRhtml/rr4909a1.htm
*  Li L[au] - PubMed - NCBI
Direct Cloning of Bacterial Surface Polysaccharide Gene Cluster for One-step Production of Glycoconjugate Vaccine. ...
  https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Li+L%5Bau%5D&dispmax=50
*  Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials | Nutrition & Metabolism | Full...
... as the vaccine is made of bacterial sugars from 23 pneumococcal types. Vaccines produced from bacterial polysaccharides are ... Larch arabinogalactanCommon cold infectionsImmune systemVaccineSCFAPolysaccharidesDietary fibersResistAid® Larix ... Polysaccharides from Larch Biomass. In: Karunaratne DDN, editor. The Complex World of Polysaccharides. InTech; 2012.Google ... Section1: General aspects of vaccination - Chapter 2: Vaccine immunology. In: al Se, editor. Vaccines. 5th ed. Amsterdam: W.B. ...
  https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-016-0086-x
*  2005, November - Journal of Young Investigators
To overcome these inherent limitations of polysaccharide antigens, new vaccine formulations have coupled bacterial ... The vaccines which we are going to consider here are non-genetic vaccines, or in simple terms, the components of these vaccines ... whereby a bacterial surface molecule binds tightly to a receptor. The bacterial molecule is expressed over the entire bacterial ... REVIEW: Mechanisms of Bacterial Pathogenesis and Targets for Vaccine Design Chief Technology Officer ...
  https://www.jyi.org/2005-november
*  Host Defenses to Intracellular Pathogens | SpringerLink
... and the importance of cross-reacting bacterial polysaccharide antigens in vaccine development. A major portion of the course ... BCG Cell Mediated Lysis Cellular Processing Interferon Lymphocytes Expressing Bacterial Antigens Mechanisms Distinct Salmonella ... encompassing topics as diverse as the mechanisms of action of bacterial toxins, the role of complement and antibody in ...
  https://link.springer.com/book/10.1007%2F978-1-4684-4481-0
*  Aalysis of immune receptor diversity and oligoclonality in responses to vaccinati - Andrew Fire
... immune receptor populations in adults before and following immunization with a conjugated bacterial polysaccharide vaccine ( ... and bacterial (meningococcal) vaccines, as well as natural infections with HI N1 influenza and varicella zoster. Our initial ... Characterize immune receptor populations in adults before and following immunization with influenza H1N1 vaccine and following ... will aid the design and testing of new vaccines. ... following protective vaccination against viral and bacterial ...
  http://grantome.com/grant/NIH/U19-AI090019-05-7081