*  Unilamellar liposome - Wikipedia
Small unilamellar liposomes/vesicles (SUVs) have sizes up to 100 nm; large unilamellar liposomes/vesicles (LUVs) may have sizes ... Unilamellar liposome is a spherical chamber/vesicle, bounded by a single bilayer of an amphiphilic lipid or a mixture of such ... There are giant unilamellar liposomes/vesicles (GUVs), which have an average diameter of 100 µm. GUVs are mostly used as models ... Phospholipid liposomes are used as targeted drug delivery systems. Hydrophilic drugs can be carried as solution inside the SUVs ...
  https://en.wikipedia.org/wiki/Unilamellar_liposome
*  Patent US6193998 - Method for producing liposomes with increased percent of compound encapsulated - Google Patents
... by use of a lipid having a carbon chain containing from about 13 to about 28 carbons during preparation of the liposomes. ... Production and Size Control of Large Unilamellar Liposomes by Emulsification Ishii, Liposome Technology, 1:111-121, 1993. ... liposomes. . . in. . . the. . . final. . . product. Amt. .. . of. . . drug. . . in. . . final. . . product. ] ... The Liposome Company, Inc.. Encapsulation of antineoplastic agents in liposomes. US5204112. Jun 12, 1987. Apr 20, 1993. The ...
  http://www.google.com/patents/US6193998?dq=3798360
*  Patent US5626870 - Method of forming hydrogel particles having a controlled size using liposomes - Google Patents
... encapsulating an effective amount of each of one or more hydrogel substances and one or more release agents in liposomes in a ... adding initiator to the liquid medium and into the liposomes, thereby initiating reaction of the one or more hydrogel ... substances, whereby hydrogel particles are formed in the liposomes, and d) removing any extra-liposomal initiator from the ... A method of fabricating hydrogel particles within liposomes, which entails: a) ...
  http://www.google.co.uk/patents/US5626870
*  Patente US20080038330 - Preparations for the application of anti-inflammatory, especially antiseptic ... - Google Patentes
a) liposomes comprising a pharmaceutically acceptable liposome membrane forming substance; and b) a 0.1 to 2% PVP iodine ... This produces much smaller, unilamellar liposomes at increased amounts of encapsulated agent. ... Small particle aerosol liposome and liposome-drug combinations for medical use. US5049389 *. 1 Dic 1989. 17 Sep 1991. Liposome ... a) liposomes comprising a pharmaceutically acceptable liposome membrane forming substance; and b) a 0.1 to 2% PVP iodine ...
  http://www.google.es/patents/US20080038330
*  Patent US6352996 - Liposomal prodrugs comprising derivatives of camptothecin and methods of ... - Google Patents
Liposomes with enhanced circulation time. US5043165. Dec 14, 1988. Aug 27, 1991. Liposome Technology, Inc.. Novel liposome ... Unilamellar liposomes, also referred to as single lamellar vesicles, are spherical vesicles comprised of one lipid bilayer ... 5,718,914; the liposomes described in U.S. Pat. No. 5,631,237; the liposome and lipid complex compositions described in U.S. ... The liposomes are preferably small unilamellar vesicles (SUV), rather than multilamellar vesicles (MLV). However, both SUVs and ...
  http://www.google.com/patents/US6352996?dq=6,373,753
*  Targeted drug delivery to mesothelioma cells using functionally selected internalizing human single-chain antibodies |...
Liposome and Immunoliposome Preparation. Fluorescently labeled unilamellar liposomes were prepared according to the repeated ... Preparation of unilamellar liposomes of intermediate size (0.1-0.2 mumol) by a combination of reverse phase evaporation and ... 32). Liposomes were composed of the diacylphospholipid, 1-2-distearoyl-3-sn-glycerophosphocholine, cholesterol, methoxy ... A, uptake of M1 scFv-targeted immunoliposomes and nontargeted liposomes by M28 cells was studied by fluorescence microscopy and ...
  http://mct.aacrjournals.org/content/7/3/569.long
*  Hyperthermia Increases Accumulation of Technetium-99m-labeled Liposomes in Feline Sarcomas | Clinical Cancer Research
Finally, advances in liposome engineering have led to the development of thermosensitive liposomes (40) . These liposomes are ... The size of the resultant large unilamellar liposomes was determined by Photon Correlation Spectroscopy (N4 Plus; Coulter Corp ... 30 min and relatively low numbers of liposomes in the tumor. By modifying the surface of liposomes using PEG,3 liposome ... Liposomes are small vesicles made of synthetic or natural lipids. Liposome size can be controlled, depending on their intended ...
  http://clincancerres.aacrjournals.org/content/6/9/3748
*  Pharmacokinetics of paclitaxel-containing liposomes in rats
Allen T, Chonn A. Large unilamellar liposomes with low uptake into the reticuloenthelial system. FEBS Lett. 1987;223:42-46. doi ... Protective effect of liposome encapsulation on paclitaxel developmental toxicity in the rat. Teratology. 1997;56:305-310. doi: ... Chonn A, Semple S, Cullis P. Separation of large unilamellar liposomes from blood components by a spin column procedure: ... Antitumor effect of taxol-containing liposomes in a taxol-resistant murine tumor model. Cancer Res. 1993;53:5877-5881. [PubMed] ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2750994/
*  Ca2+-Dependent, Phospholipid-Binding Residues of Synaptotagmin Are Critical for Excitation-Secretion Coupling In Vivo | Journal...
... unilamellar liposomes were prepared using an extruder from Avanti Polar Lipids, as described previously (Davis et al., 1999). ... Rhodamine-labeled liposome-binding assays were performed as described previously (Hui et al., 2005) in 150 μl of HEPES-buffered ... A, Immobilized WT or A-RQ or B-RQ mutant versions of Drosophila C2AB were assayed for binding PS/PC liposomes. The A-RQ and the ... B, Immobilized WT, A-RQ, or B-KQ mutant versions of mammalian C2AB were assayed for binding PS/PC liposomes. The A-RQ and the B ...
  http://www.jneurosci.org/content/28/30/7458.full
*  Antifungal Activities of Peptides Derived from Domain 5 of High-Molecular-Weight Kininogen
CF release from the liposomes was determined by monitoring the emitted fluorescence at 520 nm from a liposome dispersion (10 μM ... In particular, membrane cohesion is good, which facilitates very stable unilamellar liposomes, allowing detailed values on ... Liposome Preparation and Leakage Assay. The liposomes investigated were zwitterionic DOPC/cholesterol (60/40 mol/mol) or DOPC/ ... Indeed, these data parallel the observations on liposomes, demonstrating specificity for ergosterol (fungi-like) liposomes ...
  https://www.hindawi.com/journals/ijpep/2011/761037/
*  A Liposomal Formulation Able to Incorporate a High Content of Paclitaxel and Exert Promising Anticancer Effect
... for 10 minutes to yield small unilamellar liposomes. Paclitaxel-containing liposomes underwent filtration through a 0.2 m ... A liposome formulation for paclitaxel was developed in this study. The liposomes, composed of naturally unsaturated and ... Table 3: Effects of increasing paclitaxel to lipid molar ratio on physical properties of liposomes. Liposome formulation is ... Liposomes Made of Single PC. The liposomes composed of either HEPC or EPC alone were prepared according to the procedure ...
  https://www.hindawi.com/journals/jdd/2011/629234/
*  Lipid bilayer - Wikipedia
Chonn A, Semple SC, Cullis PR (15 September 1992). "Association of blood proteins with large unilamellar liposomes in vivo. ... Note- the term "liposome" is in essence synonymous with "vesicle" except that vesicle is a general term for the structure ... These drug-loaded liposomes travel through the system until they bind at the target site and rupture, releasing the drug. In ... The first stealth liposomes were passively targeted at tumor tissues. Because tumors induce rapid and uncontrolled angiogenesis ...
  https://en.wikipedia.org/wiki/Lipid_bilayer
*  References - Biology Online
Interaction of grepafloxacin with large unilamellar liposomes: partition and fluorescence studies reveal the importance of ... Liposome delivery of ciprofloxacin against intracellular Francisella tularensis infection. J. Control. Release. 92:265-273. ... Effects of the acyl chain composition of phosphatidylcholines on the stability of freeze-dried small liposomes in the presence ... Ciprofloxacin in polyethylene glycol-coated liposomes: efficacy in rat models of acute or chronic Pseudomonas aeruginosa ...
  http://www.biology-online.org/articles/characterization-interactions-fluoroquinolone-antibiotics-lipids/references.html
*  US4749585A - Antibiotic bonded prosthesis and process for producing same - Google Patents
Liposomes were prepared in the usual way except that the Tris buffer contained radiolabelled glycerol, 10 mg/ml. The liposome ... The phospholipid component of small unilamellar liposomes controls the rate of clearance of entrapped solutes from the ... Stability of bound liposome to plasma: The stability of bound liposomes in the presence of human plasma was determined. ... Entrapment of molecules by liposomes: The ability of the liposomes to entrap molecules in aqueous solution was tested using 14 ...
  https://patents.google.com/patent/US4749585
*  Amphotericin B - Wikipedia
Neither of these are true unilamellar liposomes like ambisome. A major barrier to the use of amphotericin in resource-poor ... The integrity of the liposome is disrupted when it binds to the fungal cell wall, but is not affected by the mammalian cell ... cholesterol and distearoyl phosphatidylglycerol that in aqueous media spontaneously arrange into unilamellar vesicles that ... membrane, so the association with liposomes decreases the exposure of the kidneys to amphotericin B, which explains its less ...
  https://en.wikipedia.org/wiki/Amphotericin_B
*  Vesosome - Wikipedia
Vesosome multicompartment structure encapsulates unilamellar liposomes within a second bilayer. For this purpose, it's ... Now, scientists plan to take full advantage of the 40 years of progress in liposome development to enhance this transportation ... It consists of one or more bilayers enclosing an aqueous core that contains unilamellar vesicles that function as internal ... It wasn't long after liposomes were first described, by British haematologist Dr Alec D Bangham in 1961 (published 1964), at ...
  https://en.wikipedia.org/wiki/Vesosome
*  Vesicle (biology and chemistry) - Wikipedia
... they are called unilamellar liposome vesicles; otherwise they are called multilamellar. The membrane enclosing the vesicle is ... Alternatively, they may be prepared artificially, in which case they are called liposomes (not to be confused with lysosomes). ... Batzri S, Korn ED (April 1973). "Single bilayer liposomes prepared without sonication". Biochim. Biophys. Acta. 298 (4): 1015-9 ...
  https://en.wikipedia.org/wiki/Vesicle_(biology_and_chemistry)
*  Patent US7141235 - Stabilized gas emulsion containing phospholipid for ultrasound contrast ... - Google Patents
Additionally, microbubbles may be trapped by a bimolecular layer (as in the case of unilamellar liposomes), or may be trapped ... In Vivo Efficacy of Reconstituted Lyophilized Liposomes. A liposome forming solution with total lipid concentration of 50 mg/ml ... It is readily appreciated that a liposome dependent contrast enhancement agent requires the prior formation of liposomes, and ... discloses phospholipid liposomes which contain a gas or gas precursor. Presumably, the gas bubbles trapped inside the liposomes ...
  http://www.google.com/patents/US7141235?dq=5463388
*  Patent US6280705 - Kits & systems for ultrasonic imaging - Google Patents
Additionally, microbubbles may be trapped by a bimolecular layer (as in the case of unilamellar liposomes), or may be trapped ... In vivo efficacy of reconstituted lyophilized liposomes. A liposome forming solution with total lipid concentration of 50 mg/ml ... It is readily appreciated that a liposome dependent contrast enhancement agent requires the prior formation of liposomes, and ... discloses phospholipid liposomes which contain a gas or gas precursor. Presumably, the gas bubbles trapped inside the liposomes ...
  http://www.google.com/patents/US6280705?dq=5,867,764
*  ASMscience | Membrane Adaptations of
Consequently, liposomes prepared from archaeal tetraether lipids are more thermostable. Bacteria respond to changes in ambient ... Choquet, C. G.,, G. B. Patel,, T. J. Beveridge, and, G. D. Sprott. 1992. Formation of unilamellar liposomes from total polar ... Liposome Res. 12:353-372. ... Chang, E. L. 1994. Unusual thermal stability of liposomes made ... Elferink, M. G.,, J. G. de Wit,, A. J. M. Driessen, and, W. N. Konings. 1994. Stability and proton-permeability of liposomes ...
  http://www.asmscience.org/content/book/10.1128/9781555815813.ch08
*  Pharmacokinetics and Efficacy of Epidurally Delivered Sustained-release Encapsulated Morphine in Dogs | Anesthesiology | ASA...
unilamellar), the drug-to-lipid load, and the potential toxicity of the liposome constituents. The DepoFoam drug-delivery ... Multivesicular liposomes differ from more conventional liposomes in that the lipid particles are substantially larger (mean ... m for unilamellar liposomes) and are composed of numerous nonconcentric internal aqueous chambers containing the encapsulated ... With regard to clearance of the liposome itself, there are few systematic data. In recent studies, we showed that after ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1946389
*  Novel applications of nanotechnology in medicine.
6.) Kirby C, Gregoriadis G. The effect of lipid composition of small unilamellar liposomes containing melphalan and vincristine ... The antibody can be conjugated to the surface of a stealth liposome, the polyoxyethylene coating of a stealth liposome or on ... Liposomes. Liposomes discovered in mid 1960s were the original models of nanoscaled drug delivery devices. They are spherical ... Liposomes measuring less than 100 nm can be used for delivery of genetic material into cells. Liposomes incorporated with ...
  http://www.biomedsearch.com/article/Novel-applications-nanotechnology-in-medicine/229530832.html
*  Lamella (cell biology) - Wikipedia
Thus, each bilayer of multilamellar liposomes and wall of a unilamellar liposome is also referred to as a lamella. Middle ...
  https://en.wikipedia.org/wiki/Lamella_(cell_biology)
*  Transfersome - Wikipedia
... or high high-shear homogenisation unilamellar liposomes) of the crude vesicle suspension. Stryer S. (1981) Biochemistry, 213 G ... Since its basic organization is broadly similar to a liposome, a Transfersome differs from more conventional vesicles primarily ... Transfersome vesicles are prepared in a similar manner as liposomes, except that no separation of the vesicle-associated and ... "What is the difference between liposomes and Transfersomes?". Scientific FAQ. IDEA AG. Medical trial that started in 2005 " ...
  https://en.wikipedia.org/wiki/Transfersome
*  Lamellar phase - Wikipedia
... and structure of lipid bilayer in unilamellar liposomes. In multilamellar liposomes, many such lipid bilayer sheets are layered ... History of cell membrane theory Lipid polymorphism Lipid bilayer Micelle Unilamellar liposome YashRoy R C (1990) Magnetic ... Existence of such a dynamic organization of lamellar phase in liposomes as well as biological membranes can be confirmed by ... resonance and high resolution nuclear magnetic resonance spectroscopy studies of biological membranes and liposomes. In 'soft ...
  https://en.wikipedia.org/wiki/Lamellar_phase