Ubiquitin-Protein Ligase E3B - Wikipedia
Ubiquitin-Protein Ligase E3B (UBE3B) is an enzyme encoded by UBE3B gene in humans. UBE3B has an N-terminal IQ motif, which ... "Loss of function of the E3 ubiquitin-protein ligase UBE3B causes Kaufman oculocerebrofacial syndrome". Journal of Medical ... "Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome". American Journal of ... "The ubiquitin ligase UBE3B, disrupted in intellectual disability and absent speech, regulates metabolic pathways by targeting ...
![UBR1 ubiquitin protein ligase E3 component n-recognin 1 [Homo sapiens (human)] - Gene - NCBI](data:image/png;base64,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)
UBR1 ubiquitin protein ligase E3 component n-recognin 1 [Homo sapiens (human)] - Gene - NCBI
ubiquitin ligase E3 alpha-I. ubiquitin-protein ligase E3-alpha. ubiquitin-protein ligase E3-alpha-1. ubiquitin-protein ligase ... UBR1 ubiquitin protein ligase E3 component n-recognin 1 [Homo sapiens] UBR1 ubiquitin protein ligase E3 component n-recognin 1 ... General protein information Go to the top of the page Help Preferred Names. E3 ubiquitin-protein ligase UBR1. Names. E3a ligase ... mRNA and Protein(s) * NM_174916.3 → NP_777576.1 E3 ubiquitin-protein ligase UBR1 ...
WikiGenes - TUL1 - ubiquitin-protein ligase TUL1
Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins. Hettema, E.H., Valdez-Taubas, J ... A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies. Reggiori, F., Pelham, H.R. Nat ... including the transmembrane ubiquitin ligase Hrd1p [1].. *We have identified a transmembrane ubiquitin ligase, Tul1, that is ... Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Katzmann ...
The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity
DTX proteins have a basic N terminus; a central proline-rich region; and a C-terminal RING finger domain, a motif often found ... The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity J Biol Chem ... a motif often found in ubiquitin-protein isopeptide ligases (E3). Recently, we identified and characterized a unique diffuse ... Herein, we report that BBAP and the human family of DTX proteins (DTX1, DTX2, and DTX3) function as E3 ligases based on their ...
E3 Ubiquitin Protein Ligase Mdm2 - Pipeline Review, H1 2020
... Summary. E3 Ubiquitin Protein Ligase Mdm2 (Double Minute 2 Protein ... E3 ubiquitin-protein ligase Mdm2 is a protein encoded by the MDM2 gene. It acts as an ubiquitin ligase E3 toward itself and ... E3 Ubiquitin Protein Ligase Mdm2 (Double Minute 2 Protein or Hdm2 or Oncoprotein Mdm2 or p53 Binding Protein Mdm2 or MDM2 or EC ... E3 Ubiquitin Protein Ligase Mdm2 (Double Minute 2 Protein or Hdm2 or Oncoprotein Mdm2 or p53 Binding Protein Mdm2 or MDM2 or EC ...
Smurf1 MGI Mouse Gene Detail - MGI:1923038 - SMAD specific E3 ubiquitin protein ligase 1
protein coding gene. Chr5:144813305-144902657 (-). 129S1/SvImJ MGP_129S1SvImJ_G0030353. protein coding gene. Chr5:150268788- ... protein coding gene. Chr5:162149104-162240007 (-). DBA/2J MGP_DBA2J_G0030170. protein coding gene. Chr5:143538244-143628935 (-) ... protein coding gene. Chr5:148288021-148376799 (-). BALB/cJ MGP_BALBcJ_G0030339. protein coding gene. Chr5:145074989-145165897 ... protein coding gene. Chr5:149102692-149196504 (-). C57BL/6NJ MGP_C57BL6NJ_G0030784. protein coding gene. Chr5:155742721- ...
IJMS | Free Full-Text | The E3 Ubiquitin-Protein Ligase RNF4 Promotes TNF-α-Induced Cell Death Triggered by RIPK1
In this study, we found that RING finger protein 4 (RNF4), a RING finger E3 ubiquitin ligase, is required for the RIPK1 ... Receptor-interacting protein kinase 1 (RIPK1) is a key component of the tumor necrosis factor (TNF) receptor signaling complex ... RING finger protein 4 (RNF4) is a RING finger E3 ubiquitin ligase classified as a small ubiquitin-related modifier (SUMO)- ... The E3 Ubiquitin-Protein Ligase RNF4 Promotes TNF-α-Induced Cell Death Triggered by RIPK1 by Tatsuya Shimada ...
Molecular Vision: p53 E3 ubiquitin protein ligase homolog regulates p53 in vivo in the adult mouse eye lens
p53 E3 ubiquitin protein ligase homolog regulates p53 in vivo in the adult mouse eye lens. Gilberto Jaramillo-Rangel,1 Marta ... p53 E3 ubiquitin protein ligase homolog (Mdm2) is an important negative regulator of p53. The purpose of this study was to ... To understand the physiologic role of p53, the effects of its expression and the proteins interacting with it in those tissues ... Similarly, large doses of ultraviolet radiation or genotoxic stress increase the content of the p53 protein in lens cells; this ...
A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin...
... wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase ... Linear motifs mediate protein-protein interactions (PPI) that allow expansion of a target protein interactome at a systems ... N2 - Linear motifs mediate protein-protein interactions (PPI) that allow expansion of a target protein interactome at a systems ... AB - Linear motifs mediate protein-protein interactions (PPI) that allow expansion of a target protein interactome at a systems ...
RCSB PDB - 6O02: Monobody (MC3) bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL
... bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL ... E3 ubiquitin-protein ligase CBL. A. 309. Homo sapiens. Mutation(s): 0 Gene Names: CBL, CBL2, RNF55. EC: 2.3.2.27. ... Monobody (MC3) bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL. Kukenshoner, T., Pojer, F., Hantschel, O.. ... Monobody (MC3) bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL. *PDB DOI: https://doi.org/10.2210/pdb6O02/ ...
E3 ubiquitin-protein ligase RBX1
E3 ubiquitin-protein ligase BRE1B, E3 ubiquitin-protein ligase DTX3L, E3 ubiquitin-protein ligase HUWE1, E3 ubiquitin-protein ... E3 ubiquitin-protein ligase RING1, E3 ubiquitin-protein ligase RING2, E3 ubiquitin-protein ligase RNF168, E3 ubiquitin-protein ... ligase RNF8, E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UHRF1, V(D)J recombination-activating protein 1 ... No disease associations known for E3 ubiquitin-protein ligase RBX1. Lysine ubiquitinases E3 ubiquitin-protein ligase BRE1A, ...
The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the...
Ubiquitin-Protein Ligases / genetics * Ubiquitin-Protein Ligases / physiology* Substances * Early Growth Response Transcription ... The E3 ubiquitin ligase Itch associated with and promoted conjugation of ubiquitin to the transcription factor TIEG1. Itch ... The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the ... These results suggest TIEG and Itch contribute to a ubiquitin-dependent nonproteolytic pathway that regulates inducible Foxp3 ...
Planteome: Term Details for 'ubiquitin protein ligase activity' (GO:0061630)
ubiquitin-like protein ligase activity (GO:0061659) ubiquitin protein ligase activity is_a ubiquitin-protein transferase ... ubiquitin protein ligase activity regulation of ubiquitin protein ligase activity (GO:1904666) RO:0002211 ubiquitin protein ... ubiquitin protein ligase activity negative regulation of ubiquitin protein ligase activity (GO:1904667) RO:0002212 ubiquitin ... Parents of ubiquitin protein ligase activity (GO:0061630) subject. relation. object. ubiquitin protein ligase activity is_a ...
ELISA Kit for Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4)
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. - NDM Research Building
Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism
Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity
... *LK ... functioned as a ubiquitin-protein ligase in vitro in the presence of a specific ubiquitin-conjugating enzyme, Ubc4-1. Mutation ... Thus, identification of a novel AR-interacting protein with ubiquitin ligase activity will stimulate further investigation into ... ligase activity. Fluorescent protein tagging studies revealed that AR-ARNIP interaction was hormone-independent in COS-1 cells ...
Frontiers | HECT E3 Ubiquitin Ligase-Regulated Txnip Degradation Facilitates TLR2-Mediated Inflammation During Group A...
... of Txnip degradation by pharmacologically inhibiting the HECT E3 ubiquitin ligase with heclin and AMP-dependent protein kinase ... of Txnip degradation by pharmacologically inhibiting the HECT E3 ubiquitin ligase with heclin and AMP-dependent protein kinase ... Thioredoxin-interacting protein (Txnip) inhibits the activity of thioredoxin (Trx) to modulate inflammatory responses. The ... Thioredoxin-interacting protein (Txnip) inhibits the activity of thioredoxin (Trx) to modulate inflammatory responses. The ...
5aiu.1 | SWISS-MODEL Template Library
Ubiquitin-protein ligases (Electronic3s) are in charge of target reputation and regulate - New dimension in therapeutic...
Ubiquitin-protein ligases (Electronic3s) are in charge of target reputation and regulate. * Post author By colinsbraincancer ... Ubiquitin-protein ligases (Electronic3s) are in charge of target reputation and regulate balance, function or localization of ... Fifteen protein through the Rsp5 high-confidence substrate arranged, and six protein that were not really defined as substrates ... All the protein whose ubiquitination was recognized for the proteins microarray had been verified to become ubiquitinated by ...
Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins...
F-box proteins bind substrates following their phosphorylation upon stimulation of various signaling pathways. Ubiquitin- ... In support of this notion, we demonstrate individual SCFPop1p and SCFPop2p complexes bearing ubiquitin ligase activity. Our ... Both proteins interact with the cullin Pcu1p when overexpressed, but it is unknown whether this reflects their co-assembly into ... SCF ubiquitin ligases share the core subunits cullin 1, SKP1, and HRT1/RBX1/ROC1, which associate with different F-box proteins ...
Recombinant Xenopus laevis E3 ubiquitin-protein ligase RING2-A (rnf2-a) | Technique alternative | 01016070326 - ...
UBE2E2 ubiquitin conjugating enzyme E2 E2 [Homo sapiens (human)] - Gene - NCBI
ubiquitin-conjugating enzyme E2E 2 (homologous to yeast UBC4/5). ubiquitin-protein ligase E2. NP_001357154.1. *EC 2.3.2.23 ... ubiquitin-conjugating enzyme E2 E2. Names. E2 ubiquitin-conjugating enzyme E2. ubiquitin carrier protein E2. ubiquitin ... Enables ISG15 transferase activity and ubiquitin conjugating enzyme activity. Involved in protein modification by small protein ... mRNA and Protein(s) * XM_047448845.1 → XP_047304801.1 ubiquitin-conjugating enzyme E2 E2 isoform X3 ...
Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis - Fingerprint -...
Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p. | Cell;143(4): 579-91, 2010 Nov 12. |...
This ERAD-L pathway requires a protein complex consisting of the ubiquitin ligase Hrd1p, which spans the ER membrane multiple ... Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p.. Carvalho, Pedro; Stanley, Ann Marie; ... Misfolded, luminal endoplasmic reticulum (ER) proteins are retrotranslocated into the cytosol and degraded by the ubiquitin/ ... and depends on both the ubiquitin ligase activity of Hrd1p and the function of the Cdc48p ATPase complex. Our results suggest a ...
Dysfunction of ubiquitin protein ligase MYCBP2 leads to cell resilience in human breast cancers<...
Dysfunction of ubiquitin protein ligase MYCBP2 leads to cell resilience in human breast cancers. NAR Cancer. 2023 Sep 1;5(3): ... Dysfunction of ubiquitin protein ligase MYCBP2 leads to cell resilience in human breast cancers. In: NAR Cancer. 2023 ; Vol. 5 ... Dysfunction of ubiquitin protein ligase MYCBP2 leads to cell resilience in human breast cancers. / Neff, Ryan A.; Bosch- ... title = "Dysfunction of ubiquitin protein ligase MYCBP2 leads to cell resilience in human breast cancers", ...
Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction...
A cardioprotective effect of ubiquitin (Ub) ligase of the C terminus of Hsc70-interacting protein (CHIP) on myocytes has been ... Dive into the research topics of Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting ... A cardioprotective effect of ubiquitin (Ub) ligase of the C terminus of Hsc70-interacting protein (CHIP) on myocytes has been ... A cardioprotective effect of ubiquitin (Ub) ligase of the C terminus of Hsc70-interacting protein (CHIP) on myocytes has been ...
Expression Levels of SMAD Specific E3 Ubiquitin Protein Ligase 2 (Smurf2) and its Interacting Partners Show Region-specific...
enQuireBio™ Recombinant Mouse Ubiquitin-protein ligase E3A Protein 50μg enQuireBio™ Recombinant Mouse Ubiquitin-protein ligase...