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*  Vav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fcγ RIIIA and is constitutively associated with a...
Tyrosine phosphorylation of Vav was inhibited by herbimycin A, a specific tyrosine kinase inhibitor. In vitro kinase assays ... cells induces receptor-associated tyrosine kinase activation and tyrosine phosphorylation of numerous intracellular proteins, ... Vav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fcγ RIIIA and is constitutively associated with a ... In addition, we observed that in LAK-NK cells, Vav was associated with a 70 kDa protein that also became tyrosine ...
  http://www.biochemj.org/content/318/2/527
*  Tyrosine and tyrosinate fluorescence of pig intestinal Ca2+-binding protein | Biochemical Journal
Tyrosine and tyrosinate fluorescence of pig intestinal Ca2+-binding protein. J D J O'Neil, T Hofmann ... Tyrosine and tyrosinate fluorescence of pig intestinal Ca2+-binding protein Message Subject (Your Name) has forwarded a page to ... The single tyrosine residue in both pig and cow intestinal Ca2+-binding proteins fluoresces at 303 nm although the crystal ... We conclude that, in solution, the tyrosine residue in this protein interacts occasionally with glutamate-38 but that a ...
  http://www.biochemj.org/content/243/2/611
*  Plus it
Janus kinase 2 (JAK2) is a cytokine receptor associated tyrosine kinase. Binding of cytokines to their specific receptors leads ... Activated JAKs phosphorylate specific tyrosine residues in the cytoplasmic chains of the receptor, which now act as docking ... Once bound to the receptor, STATs are activated by JAKs through phosphorylation of their tyrosine residues. Activated STATs ...
  http://cancerres.aacrjournals.org/content/67/9_Supplement/2390
*  Monitoring Interactions between Receptor Tyrosine Kinases and Their Downstream Effector Proteins in Living Cells Using...
RTK BRET-2 Assays Are Dependent on Autophosphorylation of Specific Tyrosine Residues. Phosphorylated tyrosine residues ... Krause DS and Van Etten RA (2005) Tyrosine kinases as targets for cancer therapy. N Engl J Med 353: 172-187. ... Robinson DR, Wu YM, and Lin SF (2000) The protein tyrosine kinase family of the human genome. Oncogene 19: 5548-5557. ... EGFR tyrosines 1068, 1086, 1101, 1114, 1148, and 1173 are involved in direct or indirect binding of the effector Grb2 (Schulze ...
  http://molpharm.aspetjournals.org/content/72/6/1440
*  Detecting Tyrosine-Phosphorylated Proteins by Western Blot Analysis - Current Protocols in Immunology - Sawasdikosol - Wiley...
Detecting Tyrosine-Phosphorylated Proteins by Western Blot Analysis. Current Protocols in Immunology. 89:11.3:11.3.1-11.3.11. ... The development of monoclonal antibodies (mAbs) that recognize nearly all of the phosphorylated tyrosine residues, irrespective ... steady improvements in reagents and detection technologies have allowed researchers to detect tyrosine phosphorylation ...
  http://onlinelibrary.wiley.com/doi/10.1002/0471142735.im1103s89/abstract
*  ABL1 | SelfDecode | Genome Analysis
... non-receptor tyrosine kinase, c-abl oncogene 1, receptor tyrosine kinase, c-abl oncoprotein 1, receptor tyrosine kinase, c-abl ... proto-oncogene tyrosine-protein kinase ABL1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase transforming protein Abl, ... Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as ... Several known tyrosine-phosphorylated microbial proteins have been identified as ABL1 substrates. This is the case of A36R of ...
  https://www.selfdecode.com/gene/abl1/
*  Injury and Trinucleotides Transactivate Specific Tyrosine Residues of the EGF Receptor Leading to Downstream Signaling | IOVS ...
Purpose: : Our goal is to evaluate the role and activation of the epidermal growth factor receptor (EGFR) tyrosine residues ... V. Trinkaus-Randall, L. Yang, I. Boucher; Injury and Trinucleotides Transactivate Specific Tyrosine Residues of the EGF ... Injury and Trinucleotides Transactivate Specific Tyrosine Residues of the EGF Receptor Leading to Downstream Signaling ... Injury and Trinucleotides Transactivate Specific Tyrosine Residues of the EGF Receptor Leading to Downstream Signaling ...
  http://iovs.arvojournals.org/article.aspx?articleid=2394805
*  IJMS | Free Full-Text | CCR7 Sulfotyrosine Enhances CCL21 Binding
... the interactions of CCL21 with peptide fragments of CCR7 containing tyrosine, pY, or sY were compared using protein NMR ( ... For many chemokine receptors, N-terminal posttranslational modifications, particularly the sulfation of tyrosine residues, ... For many chemokine receptors, N-terminal posttranslational modifications, particularly the sulfation of tyrosine residues, ... the interactions of CCL21 with peptide fragments of CCR7 containing tyrosine, pY, or sY were compared using protein NMR ( ...
  http://www.mdpi.com/1422-0067/18/9/1857
*  Mitogenic signalling pathway of tumour necrosis factor involves the rapid tyrosine phosphorylation of 41,000-Mr and 43,000-Mr...
TNF stimulated the rapid phosphorylation of two 41,000-Mr and two 43,000-Mr cytosol proteins on tyrosine, threonine and/or ... In contrast, bombesin, which is an even better mitogen for Swiss 3T3 cells than TNF, stimulated the tyrosine phosphorylation of ... Mitogenic signalling pathway of tumour necrosis factor involves the rapid tyrosine phosphorylation of 41,000-Mr and 43,000-Mr ... Mitogenic signalling pathway of tumour necrosis factor involves the rapid tyrosine phosphorylation of 41,000-Mr and 43,000-Mr ...
  http://www.biochemj.org/content/267/1/91
*  Purinergic stimulation of rat cardiomyocytes induces tyrosine phosphorylation and membrane association of phospholipase Cγ: a...
The purine triggers a significant phosphorylation on tyrosine residues of a cytosolic pool of PLCγ with a time course that ... All these events (translocation and phosphorylation of PLCγ, InsP3 formation) are blocked by genistein, a tyrosine kinase ... We thus propose that the purinergic stimulation activates a non-receptor tyrosine kinase that phosphorylates PLCγ in the ... Purinergic stimulation of rat cardiomyocytes induces tyrosine phosphorylation and membrane association of phospholipase Cγ: a ...
  http://www.biochemj.org/content/318/2/723
*  Detection of a 60 kDa tyrosine-phosphorylated protein in insulin-stimulated hepatoma cells that associates with the SH2 domain...
Activation of the tyrosine kinase activity of the insulin receptor by autophosphorylation leads to phosphorylation of cellular ... Binding of p60 to p85 is similar to the interaction between p85 and IRS-1 in that a tyrosine-phosphorylated peptide containing ... The 60 kDa protein in hepatoma cells is tyrosine-phosphorylated in response to insulin in a dose-dependent manner, with maximal ... Detection of a 60 kDa tyrosine-phosphorylated protein in insulin-stimulated hepatoma cells that associates with the SH2 domain ...
  http://www.biochemj.org/content/308/2/579
*  Tyrosine phosphorylation induced by EGF stimulation. Ce | Open-i
Tyrosine phosphorylation induced by EGF stimulation. Cells were grown to confluence and quiesced with the DME containing 0.1% ... Figure 2: Tyrosine phosphorylation induced by EGF stimulation. Cells were grown to confluence and quiesced with the DME ... Figure 2: Tyrosine phosphorylation induced by EGF stimulation. Cells were grown to confluence and quiesced with the DME ... Cells were then lysed, and equal volumes of proteins were analyzed for phospho-tyrosine (a) and phospho-erk-MAPK (b) by ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2199733_JCB9812049.f2&req=4
*  Details-Calcnet-TargetNet
P00519: Tyrosine-protein kinase ABL1. Protein function Non-receptor tyrosine-protein kinase that plays a role in many key ... Several known tyrosine-phosphorylated microbial proteins have been identified as ABL1 substrates. This is the case of A36R of ... Phosphorylates multiple receptor tyrosine kinases and more particularly promotes endocytosis of EGFR, facilitates the formation ... Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 ( ...
  http://targetnet.scbdd.com/home/details/P00519/
*  Tyrosine phosphorylation of Syk after stimulation of NK | Open-i
Tyrosine phosphorylation of Syk after stimulation of NK cells with targets. For each sample, 107 NK cells were mixed with 5 × ... Figure 1: Tyrosine phosphorylation of Syk after stimulation of NK cells with targets. For each sample, 107 NK cells were mixed ... Figure 1: Tyrosine phosphorylation of Syk after stimulation of NK cells with targets. For each sample, 107 NK cells were mixed ... We observed an increase in Syk tyrosine phosphorylation after NK cells were stimulated with each of the panel of targets (Fig. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2199178_JEM.971432f1a&req=4
*  VASCULAR INJURY CHANGE TYROSINE PHOSPHORYLATION OF FOCAL ADHESION PROTEINS | Heart
Objectives To identify the major tyrosine-phosphorylated proteins in the normal artery and their changes after balloon injury. ... The artery contained greater amount of tyrosine-phosphorylated FAK than that in the other tissues examined, including the ... blot analyses with three different antibodies against phosphotyrosine revealed that pp68 and pp125 were the two major tyrosine- ...
  http://heart.bmj.com/content/98/Suppl_2/E55.2
*  Tyrosine hydroxylase - Wikipedia
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L- ... Tyrosine hydroxylase catalyzes the reaction in which L-tyrosine is hydroxylated in the meta position to obtain L-3,4- ... Tyrosine hydroxylase can be inhibited by the drug α-methyl-para-tyrosine (metirosine). This inhibition can lead to a depletion ... Tyrosine hydroxylase catalyzes conversion of tyrosine to L-DOPA using Fe2+, O2 and BH4 ...
  https://en.wikipedia.org/wiki/Tyrosine_3-monooxygenase
*  TYROSINE KINASE INHIBITORS
... PRESENTED BY: Y.VIJAY FINAL YEAR POST GRADUATEDEPARTMENT OF PHARMACOLOGY OSMANIA MEDICAL COLLEGE ... 5. TYPES OF TYROSINE KINASES• Tyrosine kinases can be further subdivided into1. Receptor tyrosine kinases eg: EGFR, PDGFR, ... TYROSINE KINASE INHIBITORS * 1. TYROSINE KINASE INHIBITORS PRESENTED BY: Y.VIJAY FINAL YEAR POST GRADUATEDEPARTMENT OF ... 9. TYROSINE KINASE INIBITORS1. BCR-ABL Tyrosine Kinase Inhibitors eg: Imatinib Mesylate, Dasatinib, and Nilotinib.2. Epidermal ...
  https://www.slideshare.net/vj2510/tyrosine-kinase-inhibitors
*  L-tyrosine (CHEBI:17895)
... is enantiomer of D-tyrosine (CHEBI:28479) L-tyrosine (CHEBI:17895) is tautomer of L-tyrosine ... L-tyrosine (CHEBI:17895). L-tyrosin-O4-yl group (CHEBI:32768) is substituent group from L-tyrosine (CHEBI:17895). L-tyrosine ... L-tyrosine (CHEBI:17895) is a proteinogenic amino acid (CHEBI:83813) L-tyrosine (CHEBI:17895) is a tyrosine (CHEBI:18186) L- ... L-tyrosine (CHEBI:17895) has role nutraceutical (CHEBI:50733) L-tyrosine (CHEBI:17895) is a L-α-amino acid (CHEBI:15705) L- ...
  https://www.ebi.ac.uk/chebi/es/searchId.do?chebiId=CHEBI:17895
*  Talk:Tubulin-tyrosine ligase - Wikipedia
Retrieved from "https://en.wikipedia.org/w/index.php?title=Talk:Tubulin-tyrosine_ligase&oldid=420266952" ...
  https://en.wikipedia.org/wiki/Talk:Tubulin%E2%80%94tyrosine_ligase
*  Leukocyte receptor tyrosine kinase - Wikipedia
... spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine ... Leukocyte receptor tyrosine kinase is an enzyme that in humans is encoded by the LTK gene. The protein encoded by this gene is ... Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and ... "Entrez Gene: LTK leukocyte tyrosine kinase". Lopes SS, Yang X, Müller J, Carney TJ, McAdow AR, Rauch GJ, Jacoby AS, Hurst LD, ...
  https://en.wikipedia.org/wiki/Leukocyte_receptor_tyrosine_kinase
*  L-Tyrosine - Everything2.com
... tyrosine' which leads to the production of norepinephrine, epinephrine (adrenaline), and thyroid hormone. The ... ... Tyrosine. Saint John's wort. A medical explanation of the effects of ecstasy on your body. Sleep cycle strategies. ... The human body also uses l-tyrosine to make serotonin and dopamine, two important neurotransmitters. Some reported effects of ... Natural form of the amino acid "tyrosine" which leads to the production of norepinephrine, epinephrine (adrenaline), and ...
  https://everything2.com/title/L-Tyrosine
*  Oncogenic protein tyrosine kinases | SpringerLink
Signals through Kit receptor tyrosine kinase are essential for development of erythrocytes, melanocytes, germ cells, mast cells ... Signals through Kit receptor tyrosine kinase are essential for development of erythrocytes, melanocytes, germ cells, mast cells ...
  https://link.springer.com/article/10.1007%2Fs00018-004-4273-y
*  tyrosine kinase inhibitor (CHEBI:38637)
1-NA-PP1 (CHEBI:52310) has role tyrosine kinase inhibitor (CHEBI:38637). 1-NM-PP1 (CHEBI:52309) has role tyrosine kinase ... BE-23372M (CHEBI:65473) has role tyrosine kinase inhibitor (CHEBI:38637). biochanin A (CHEBI:17574) has role tyrosine kinase ... bosutinib hydrate (CHEBI:68533) has role tyrosine kinase inhibitor (CHEBI:38637). butein (CHEBI:3237) has role tyrosine kinase ... masitinib (CHEBI:63450) has role tyrosine kinase inhibitor (CHEBI:38637). melemeleone B (CHEBI:66690) has role tyrosine kinase ...
  https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:38637
*  Tyrosine - Wikipedia
Tyrosine residues may also be modified by the addition of a sulfate group, a process known as tyrosine sulfation.[7] Tyrosine ... namely meta-tyrosine (also known as 3-hydroxyphenylalanine, L-m-tyrosine, and m-tyr) and ortho-tyrosine (o-tyr or 2- ... It transforms L-tyrosine into p-coumaric acid. Precursor to pigmentsEdit. Tyrosine is also the precursor to the pigment melanin ... Ortho- and meta-tyrosineEdit. Enzymatic oxidation of tyrosine by phenylalanine hydroxylase (top) and non-enyzmatic oxidation by ...
  https://en.m.wikipedia.org/wiki/Tyrosine