*  RASSF5 Pre-design Chimera RNAi - (H00083593-R01) - Products - Abnova
It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes ... Ras effector-like protein,novel Ras effector 1,regulator for cell adhesion and polarization enriched in lymphoid tissue,tumor ... The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript ... OTTHUMP00000034534,OTTHUMP00000034535,Rap1-binding protein,Ras association (RalGDS/AF-6) domain family 5, ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=H00083593-R01
*  RASSF1 Pre-design Chimera RNAi - (H00011186-R06) - Products - Abnova
... which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the ... The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation ... This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated ... Ras association domain family protein 1,WUGSC:H_LUCA12.5,cardiac-specific ras association domain family 1 protein,pancreas- ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=H00011186-R06
*  OriGene - GLTSCR1 (NM 015711) cDNA Clone
Human glioma tumor suppressor candidate region gene 1 (GLTSCR1) available for purchase from OriGene - Your Gene Company. ... Lenti ORF clone of Gltscr1 (Myc-DDK-tagged) - Mouse glioma tumor suppressor candidate region gene 1 (Gltscr1). $2090. 7 weeks. ... Protein Request. Antibody. OriGene Data. Vector:. pCMV6-XL With the native stop codon at the end of the ORF, the C-terminal Myc ... Lenti ORF clone of Gltscr1 (Myc-DDK-tagged) - Mouse glioma tumor suppressor candidate region gene 1 (Gltscr1). $2090. 9 weeks. ...
  http://www.origene.com/cdna/trueclone/accession/NM_015711/SC318640.aspx
*  Tumor Suppressor Proteins - Proteins, Tumor Suppressor Summary Report | CureHunter
Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development. ... Proteins that are normally involved in holding cellular growth in check. ... Tumor Suppressor Proteins (Proteins, Tumor Suppressor). Subscribe to New Research on Tumor Suppressor Proteins ... Proteins, Tumor Suppressor; Proteins, Growth Suppressor; Proteins, Metastasis Suppressor; Growth Suppressor Proteins; ...
  http://www.curehunter.com/public/keywordSummaryD025521-Tumor-Suppressor-Proteins-Proteins--Tumor-Suppressor.do
*  Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations.
... tumor suppressor gene product, merlin (schwannomin) forms an intramolecular association that is required for negative growth ... we propose a model for merlin folding critical to its ability to function as a tumor suppressor protein.. ... In an effort to develop a molecular model for merlin relevant to its tumor suppressor function, we further characterized merlin ... Membrane Proteins / genetics*. Microtubules / chemistry. Neurofibromatosis 2 / genetics*. Neurofibromin 2. Protein Structure, ...
  http://www.biomedsearch.com/nih/Neurofibromatosis-2-tumor-suppressor-protein/10561699.html
*  Transcriptional regulation by the Wilms' tumour suppressor protein WT1 | Biochemical Society Transactions
Abbreviations: WT1, Wilms' tumour suppressor protein; BASP1, brain acid soluble protein 1; SD, suppression domain; IGFII, ... Transcriptional regulation by the Wilms' tumour suppressor protein WT1. K.J. Wagner, S.G.E. Roberts ... The Wilms' tumour suppressor protein WT1 is mutated in approx. 15% of Wilms' tumours, and is aberrantly expressed in many ... The Wilms' tumour suppressor protein WT1 is a transcriptional activator, the function of which is under cell-context-specific ...
  http://www.biochemsoctrans.org/content/32/6/932
*  Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells. | Sigma-Aldrich
Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells.. [Byong Hoon Yoo, Alexander ... Chk2 can kill cells by stabilizing p53 tumor suppressor protein or via p53-independent mechanisms, and we established that Chk2 ... Thus, oncogenic ras can prevent Chk2 from triggering anoikis even when levels of this protein kinase are elevated in cancer ... a pro-apoptotic protein kinase that has never been implicated in anoikis and has been thought to kill cells mainly under the ...
  https://www.sigmaaldrich.com/catalog/papers/21834075
*  Tetramer Stability and Functional Regulation of Tumor Suppressor Protein p53 | Springer for Research & Development
... and quantitative analysis of the effects of tumor-derived mutations on the tetrameric structure of tumor suppressor protein p53 ... and quantitative analysis of the effects of tumor-derived mutations on the tetrameric structure of tumor suppressor protein p53 ... This work suggests that the threshold for loss of tumor suppressor activity, in terms of the disruption of p53's tetrameric ... A small destabilization of the tetrameric structure therefore could result in dysfunction of tumor suppressor activity. ...
  https://rd.springer.com/book/10.1007/978-4-431-54135-6
*  The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth | JCB
Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein. J. Am. Soc. ... The von Hippel-Lindau tumor suppressor protein influences microtubule dynamics at the cell periphery. Exp. Cell Res. 301:139- ... Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL. Nat. Cell Biol. 5:64-70. ... The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth. Bernhard Schermer, ...
  http://jcb.rupress.org/content/175/4/547
*  DIGITAL.CSIC: Cytoplasmic interaction of the tumour suppressor protein hSNF5 with dynamin-2 controls endocytosis
Cytoplasmic interaction of the tumour suppressor protein hSNF5 with dynamin-2 controls endocytosis. ... is a component of the human SWI/SNF chromatin remodelling complex and a tumour suppressor mutated in rhabdoid tumours. It also ... and open new perspectives in understanding the role of hSNF5 in tumour genesis.. © 2014 Macmillan Publishers Limited All rights ...
  https://digital.csic.es/handle/10261/123202
*  The role of the Wilms' tumour-suppressor protein WT1 in apoptosis | Biochemical Society Transactions
The role of the Wilms' tumour-suppressor protein WT1 in apoptosis Message Subject (Your Name) has forwarded a page to you from ... The role of the Wilms' tumour-suppressor protein WT1 in apoptosis. Jörg Hartkamp, Stefan G.E. Roberts ... The Wilms' tumour-suppressor gene (WT1), encodes a zinc-finger transcription factor that is critical for the development of ... Wilms' tumour suppressor (WT1). Footnotes. *. Transcription: A Biochemical Society Focused Meeting held at the University of ...
  http://www.biochemsoctrans.org/content/36/4/629
*  Tumor-suppressor Protein Gives Up Its Secrets
Genetic mutations aren't the only thing that can keep a protein called PTEN from doing its tumor-suppressing job. Johns Hopkins ... In addition to phosphate tags, mutations in genes that code for a protein can cause some protein activities to be permanently ... both deadly aspects of tumor progression.. Cole explains that when a cell needs to divide, another protein, most often CK2, ... Its tail curls back on the rest of the protein and prevents it from interacting with PIP3 in the outer envelope of the cell, so ...
  https://www.technologynetworks.com/cell-science/news/tumorsuppressor-protein-gives-up-its-secrets-212514
*  Clinical stratification of glioblastoma based on alterations in retinoblastoma tumor suppressor protein (RB1) and association...
... xenografts identified retinoblastoma tumor suppressor protein RB1 status as a determinant of tumor therapeutic efficacy. ... Assessment of RB1 protein loss in tumor cells. (A-E) Two RB1-immunonegative tumors were either homozygous (A, B) or hemizygous ... Clinical stratification of glioblastoma based on alterations in retinoblastoma tumor suppressor protein (RB1) and association ... Clinical Stratification of Glioblastoma Based on Alterations in Retinoblastoma Tumor Suppressor Protein (RB1) and Association ...
  https://www.ncbi.nlm.nih.gov/pubmed/22157621
*  Activation of PAR-1 Kinase and Stimulation of Tau Phosphorylation by Diverse Signals Require the Tumor Suppressor Protein LKB1 ...
Here we show that phosphorylation of PAR-1 by the tumor suppressor protein LKB1 is required for PAR-1 activation, which in turn ... These results reveal a new function for the tumor suppressor protein LKB1 in a signaling cascade through which the ... Using a combination of biochemical and genetic analyses, we found that the tumor suppressor protein LKB1 is an upstream ... Activation of PAR-1 Kinase and Stimulation of Tau Phosphorylation by Diverse Signals Require the Tumor Suppressor Protein LKB1 ...
  http://www.jneurosci.org/content/27/3/574
*  Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolerance to morphine
... Tan-No, Koichi ... The present study was designed to determine whether the p53 tumor-suppressor protein is involved in the development of ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:302486
*  p21WAF1 (Tumor Suppressor Protein) Antibody - Mouse Monoclonal Antibody [Clone HJ21 ] IHC, IF, FC - Buy Now! |Abgent
p21WAF1 (Tumor Suppressor Protein) Antibody, Mouse Monoclonal Antibody [Clone HJ21 ] validated in IHC, IF, FC (AH10998-7), ... home , Products , Primary Antibodies , Cell Biology , p21WAF1 (Tumor Suppressor Protein) Antibody p21WAF1 (Tumor Suppressor ... This MAb recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. It is highly specific to p21 and shows ... p21WAF1 (Tumor Suppressor Protein) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. ...
  http://www.abgent.com/products/AH10998-p21WAF1-Tumor-Suppressor-Protein-Antibody
*  Inhibition of Vascular Smooth Muscle Cell Proliferation, Migration, and Survival by the Tumor Suppressor Protein PTEN |...
Inhibition of Vascular Smooth Muscle Cell Proliferation, Migration, and Survival by the Tumor Suppressor Protein PTEN. Jianhua ... In this report, we investigated the hypothesis that overexpression of the tumor suppressor protein PTEN, an inositol ... Inhibition of Vascular Smooth Muscle Cell Proliferation, Migration, and Survival by the Tumor Suppressor Protein PTEN ... Inhibition of Vascular Smooth Muscle Cell Proliferation, Migration, and Survival by the Tumor Suppressor Protein PTEN ...
  http://atvb.ahajournals.org/content/22/5/745
*  The structure of p53 tumour suppressor protein reveals the basis for its funcitonal plasticity - White Rose Research Online
p53 major tumour suppressor protein has presented a challenge for structural biology for two decades. The intact and complete ... 5 more authors) (2006) The structure of p53 tumour suppressor protein reveals the basis for its funcitonal plasticity. EMBO ... The structure of p53 tumour suppressor protein reveals the basis for its funcitonal plasticity ... essential for p53 transactivation and tumour suppressor functions. ...
  http://eprints.whiterose.ac.uk/6065/
*  Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells | Journal of Cell Science
Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells ... Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells ... Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells ... Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells ...
  http://jcs.biologists.org/content/early/2010/03/31/jcs.068015
*  ADP-ribosylation factor-like tumour-suppressor protein 1 | definition of ADP-ribosylation factor-like tumour-suppressor protein...
What is ADP-ribosylation factor-like tumour-suppressor protein 1? Meaning of ADP-ribosylation factor-like tumour-suppressor ... protein 1 medical term. What does ADP-ribosylation factor-like tumour-suppressor protein 1 mean? ... ADP-ribosylation factor-like tumour-suppressor protein 1 explanation free. ... Looking for online definition of ADP-ribosylation factor-like tumour-suppressor protein 1 in the Medical Dictionary? ...
  http://medical-dictionary.thefreedictionary.com/ADP-ribosylation+factor-like+tumour-suppressor+protein+1
*  Adenomatous Polyposis Coli Tumor Suppressor Protein Has Signaling Activity in Xenopus laevis Embryos Resulting in the Induction...
... tumor suppressor protein (23) and a novel protein EB1 (52). In addition, the COOH terminus can bind to microtubules and promote ... 1996) Binding of APC to the human homolog of the Drosophiladisc large tumor suppressor protein. Science (Wash DC) 272:1020-1023 ... 1993) Association of the APC tumor suppressor protein with catenins. Science (Wash DC) 262:1734-1737, pmid:8259519.. ... Adenomatous Polyposis Coli Tumor Suppressor Protein Has Signaling Activity in Xenopus laevis Embryos Resulting in the Induction ...
  http://jcb.rupress.org/content/136/2/411
*  Cancer - Copy - Tumor-suppressor genes help prevent uncontrolled cell growth Tumor-suppressor Proteins Repair of damaged DNA...
Tumor-suppressor genes help prevent uncontrolled cell growth Tumor-suppressor Proteins: Repair of damaged DNA, control cell ... Unformatted text preview: Tumor-suppressor genes help prevent uncontrolled cell growth Tumor-suppressor Proteins: Repair of ... pathway Ras proto-oncogen p53 tumor-suppressor gene Multistep Model 1 active oncogene mutation in several tumor-suppressor ... In that case the tumor is called a benign tumor Most benign tumors do not cause ...
  https://www.coursehero.com/file/6265925/Cancer-Copy/
*  481044: p53 Tumor Suppressor Gene Protein,... | LabCorp
Accumulation of p53 tumor suppressor gene protein: An independent marker of prognosis in breast cancers. J Natl Cancer Inst. ... p53 Tumor Suppressor Gene Protein, Immunohistochemical, Paraffin Block. TEST: 481044 Test number copied ... Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J ... Alterations of the p53 tumor suppressor gene have been shown to serve as an independent prognostic marker in a wide variety of ...
  https://www.labcorp.com/test-menu/32621/p53-tumor-suppressor-gene-protein-immunohistochemical-paraffin-block
*  p53 Tumor Suppressor Protein Antibody - Without BSA and Azide - Mouse Monoclonal Antibody [Clone BP53-12 ] WB, IHC-P, IF, FC -...
p53 Tumor Suppressor Protein Antibody - Without BSA and Azide, Mouse Monoclonal Antibody [Clone BP53-12 ] validated in WB, IHC- ... p53 Tumor Suppressor Protein Antibody - Without BSA and Azide p53 Tumor Suppressor Protein Antibody - Without BSA and Azide. ... p53 Tumor Suppressor Protein Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or ... Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances ...
  http://www.abgent.com/products/AH10775-p53-Tumor-Suppressor-Protein-Antibody-Without-BSA-and-Azide
*  Aggregation dynamics and identification of aggregation-prone mutants of the von Hippel Lindau tumor suppressor protein |...
Aggregation dynamics and identification of aggregation-prone mutants of the von Hippel Lindau tumor suppressor protein ... Aggregation dynamics and identification of aggregation-prone mutants of the von Hippel Lindau tumor suppressor protein ... Aggregation dynamics and identification of aggregation-prone mutants of the von Hippel Lindau tumor suppressor protein ... Aggregation dynamics and identification of aggregation-prone mutants of the von Hippel Lindau tumor suppressor protein ...
  http://jcs.biologists.org/content/early/2016/05/12/jcs.184846