*  Malignant Peripheral Nerve Sheath Tumors: Differentiation Patterns and Immunohistochemical Features - A Mini-Review and Our New...
Ramanathan RC, Thomas J. M Malignant peripheral nerve sheath tumours associated with von Recklinghausen's neurofibromatosis. ... WHO classification of tumors-pathology and genetics of tumors of the nervous system; 4th Edition. WHO. 2007:160. ... The tumor recurred in the original site 10 months after tumor resection. Imaging examination demonstrated muscular invasion; ... of the tumors [8]. In high grade MPNST, only scattered, if any, tumor cells are S-100 positive [1, 23]. On the other hand, ...
  http://jcancer.org/v03p0303.htm
*  Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas - Full Text View...
Nerve Sheath Tumor. Antifibrotic Agent. Volumetric Tumor Measurement. Plexiform Neurofibroma. Neurofibromatosis Type 1. ... Neurofibromatoses. Neurofibroma. Neurofibromatosis 1. Neurofibroma, Plexiform. Nerve Sheath Neoplasms. Neoplasms, Nerve Tissue ... Genetics Home Reference related topics: neurofibromatosis type 1 neurofibromatosis type 2 MedlinePlus related topics: ... Genetic and Rare Diseases Information Center resources: Neurofibromatosis Neurofibroma Neurofibromatosis Type 1 ...
  https://clinicaltrials.gov/ct2/show/NCT00076102?cond=%22Neurofibromatosis%22&rank=16
*  Nucleocytoplasmic transfer of the NF2 tumor suppressor protein merlin is regulated by exon 2 and a CRM1-dependent nuclear...
The neurofibromatosis 2 protein merlin is a classical tumor suppressor protein. Germline mutations predispose to the ... Merlin has been regarded as an exception in not exerting a functional role within the nucleus as other tumor suppressors do. ... Merlin has been regarded as an exception in not exerting a functional role within the nucleus as other tumor suppressors do. ... The neurofibromatosis 2 protein merlin is a classical tumor suppressor protein. Germline mutations predispose to the ...
  http://oxfordindex.oup.com/view/10.1093/hmg/11.19.2269
*  benign bone neurilemmoma 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Title] Benign bony and soft tissue tumors of the hand.. *It is important to be familiar with the wide variety of benign tumors ... although sometimes associated with neurofibromatosis, most occur as isolated lesions and arise from branches of the ciliary or ... Intraosseous neurilemmoma (schwannoma) is a rare bone tumor with incidence less than 0.2% of all primary bone tumors. ... Glomus Tumor / blood supply. Glomus Tumor / surgery. Hearing Loss / etiology. Hoarseness / etiology. Humans. Infant. Male. ...
  http://www.bmlsearch.com/?kwr=benign+bone+neurilemmoma+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  DMOZ - Health: Conditions and Diseases: Cancer: Musculoskeletal: Soft Tissue Sarcoma: Malignant Peripheral Nerve Sheath Tumors
Also referred to as Peripheral nervous system tumor or malignant peripheral nerve sheath tumor. ... Also referred to as Peripheral nervous system tumor or malignant peripheral nerve sheath tumor. ... "Health ... Malignant Peripheral Nerve Sheath Tumors" search on: AOL - Ask - Bing - DuckDuckGo - Gigablast - Google - ixquick - ... Health Conditions and Diseases Cancer Musculoskeletal Soft Tissue Sarcoma Malignant Peripheral Nerve Sheath Tumors 3 ...
  http://dmoztools.net/Health/Conditions_and_Diseases/Cancer/Musculoskeletal/Soft_Tissue_Sarcoma/Malignant_Peripheral_Nerve_Sheath_Tumors/
*  Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas - Full Text View ...
Patients with the genetic disorder neurofibromatosis Type 1 (NF1) are at increased risk of developing tumors of the central and ... This surgery can be possible on a single and limited tumor. On the other hand these tumors are often surgically intractable due ... Genetics Home Reference related topics: neurofibromatosis type 1 neurofibromatosis type 2 MedlinePlus related topics: ... Neurofibromatosis 1. Neurofibromatoses. Neurofibroma. Nerve Sheath Neoplasms. Neurofibroma, Plexiform. Neoplasms, Nerve Tissue ...
  https://clinicaltrials.gov/ct2/show/NCT01412892?cond=%22neurofibromatosis+type+1%22&rank=4
*  Plexiform Neurofibroma Market Research Report: Forecast up to 2024 - BizPR.us | US Free Press Release and Distribution center
Being associated with neurofibromatosis type I, pNFs either reoccur or transform in a malignant stage. Moreover, the tumors are ... Tumors continue to regrow post-surgery and patients have to undergo multiple surgical interventions. Rapid tumor growth, tumor ... Another type of tumor that commonly affects NF1 patients is plexiform neurofibromas (pNFs) market. It is a benign tumor ... Patients with NF1 have several tumors associated with nervous system and other body organs. These tumors are non-cancerous, ...
  http://bizpr.us/2017/07/19/plexiform-neurofibroma-market-research-report-forecast-2024/
*  Upper digestive hemorrhage in a patient with von Recklinghausen neurofibromatosis
It is characterised by the development of tumors in diverse sites, which may be benign or malignant. ... Upper digestive hemorrhage in a patient with von Recklinghausen neurofibromatosis. Yuste JR, Beloqui O, de la Peña A, Bilbao I ... Neurofibromatosis (Von Recklinghausen's disease) is uninherited as an autosomal dominant trait. ... Mesenteric angiography demonstrated a hypervascular tumour in the jejunum. It was surgically excised with an ...
  https://www.cun.es/en/research/scientific-publications/upper-digestive-hemorrhage-in-a-patient-with-von-recklinghausen-neurofibromatosis
*  Malignant peripheral nerve sheath tumor - Wikipedia
Zehou, Ouidad (2013). "Chemotherapy For The Treatment Of Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis 1: A 10- ... Difficulty in moving the extremity that has the tumor, including a limp. Soreness localized to the area of the tumor or in the ... co-existent neurofibromatosis, and the presence of metastases. It is a rare tumor type, with a relatively poor prognosis in ... taking a sample of cells directly from the tumor itself). MRIs, X-rays, CT scans, and bone scans can aid in locating a tumor ...
  https://en.wikipedia.org/wiki/Malignant_peripheral_nerve_sheath_tumor
*  Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations.
... tumor suppressor gene product, merlin (schwannomin) forms an intramolecular association that is required for negative growth ... Based on these findings, we propose a model for merlin folding critical to its ability to function as a tumor suppressor ... The neurofibromatosis 2 (NF2) tumor suppressor gene product, merlin (schwannomin) forms an intramolecular association that is ... In an effort to develop a molecular model for merlin relevant to its tumor suppressor function, we further characterized merlin ...
  http://www.biomedsearch.com/nih/Neurofibromatosis-2-tumor-suppressor-protein/10561699.html
*  Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders | Clinical Cancer...
Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders. D. Gareth R. Evans ... Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders ... Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders ... Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders ...
  http://clincancerres.aacrjournals.org/content/23/12/e54.figures-only
*  Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors - Full Text View -...
The purpose of this study is to determine if Lapatinib has any effect on tumors found in patients with Neurofibromatosis Type 2 ... Neuroendocrine Tumors. Neuroectodermal Tumors. Neoplasms, Germ Cell and Embryonal. Neuroma. Cranial Nerve Neoplasms. Neoplasms ... Genetics Home Reference related topics: Neurofibromatosis type 1 Neurofibromatosis type 2 MedlinePlus related topics: ... Neurofibromatoses. Neurofibromatosis 1. Neurofibroma. Neurilemmoma. Neuroma, Acoustic. Nerve Sheath Neoplasms. Neoplasms, Nerve ...
  https://clinicaltrials.gov/ct2/show/NCT00973739?cond=%22Neurofibromatosis+type+2%22&rank=1
*  Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors - Full Text View -...
The purpose of this study is to determine if Lapatinib has any effect on tumors found in patients with Neurofibromatosis Type 2 ... Neuroendocrine Tumors. Neuroectodermal Tumors. Neoplasms, Germ Cell and Embryonal. Neuroma. Cranial Nerve Neoplasms. Neoplasms ... Neurofibromatoses. Neurofibroma. Neurilemmoma. Neuroma, Acoustic. Neurofibromatosis 2. Nerve Sheath Neoplasms. Neoplasms, Nerve ... Currently there are no available treatment options for NF2 patients with multiple tumors. Depending on tumor cell type, ...
  https://clinicaltrials.gov/ct2/show/NCT00973739?cond=%22Acoustic+neuroma%22&rank=11
*  Resection of 2 Intradural Extramedullary Cervical Spine Tumors in a Patient With Neurofibromatosis Type 2: 3-Dimensional...
"Resection of 2 Intradural Extramedullary Cervical Spine Tumors in a Patient With Neurofibromatosis Type 2: 3-Dimensional ... The with neurofibromatosis type 2. The patient presented dural closure was performed in watertight fashion with lower extremity ... The with neurofibromatosis type 2. The patient presented dural closure was performed in watertight fashion with lower extremity ... Disclosure schwannomas and/or neurofibromas are usually among the easier spinal cord tumors to resect, this case is interesting ...
  https://www.deepdyve.com/lp/ou_press/resection-of-2-intradural-extramedullary-cervical-spine-tumors-in-a-9TWEblT0j3
*  Search of: 'Neurofibromatosis type 2' - List Results - ClinicalTrials.gov
Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors. *Neurofibromatosis 2 ... Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients. *Neoplasms ... Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype. *Neurofibromatosis. * ... 39 Studies found for: 'Neurofibromatosis type 2'. Also searched for Neurofibromatosis 2, Neurofibromatosis type II, and NF2. ...
  https://clinicaltrials.gov/ct2/results?cond=%22Neurofibromatosis+type+2%22&show_rss=Y&sel_rss=new14
*  Search of: Neurodegenerative Diseases | 'neurofibromatosis type 2' OR 'neurofibromatosis' - List Results - ClinicalTrials.gov
Analysis of Peripheral Nerve Sheath Tumors (PNSTs) in Neurofibromatosis Type 1 (NF1) Patients. *Neurofibromatosis Type 1 ... Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors. *Neurofibromatosis 2 ... Detected NF-1 gene expression pattern in neurofibromatosis-asociated tumor. 300. All. Child, Adult, Senior. NCT03359304. PKU- ... Neurofibromatosis Type 1 Patient Registry. *Neurofibromatosis Type 1. Observational. *Washington University School of Medicine ...
  https://clinicaltrials.gov/ct2/results?term=Neurodegenerative+Diseases&cond=%22neurofibromatosis+type+2%22+OR+%22neurofibromatosis%22
*  Frontiers | Meningioma Genomics: Diagnostic, Prognostic, and Therapeutic Applications | Surgery
Genomic features of meningioma further associate with tumor location, histologic subtype, and possibly clinical behavior. Such ... Genomic features of meningioma further associate with tumor location, histologic subtype, and possibly clinical behavior. Such ... Meningioma as an Invasive Tumor. Independent of tumor classification, the clinical course of meningiomas following surgical ... Molecular genetics of neurofibromatosis 2 and related tumors (acoustic neuroma and meningioma). Ann N Y Acad Sci (1991) 615:338 ...
  https://www.frontiersin.org/articles/10.3389/fsurg.2016.00040/full
*  WikiGenes - Meningioma
Genotype-phenotype correlations for nervous system tumors in neurofibromatosis 2: a population-based study. Baser, M.E., ... Inhibition of tumor-induced migration of bovine capillary endothelial cells by mouse and rabbit tumor necrosis factor. Mano- ... Schwannomas and meningiomas occur as multiple tumors in sufferers of neurofibromatosis 2 (NF2) and as solitary tumors in the ... CCK-A receptors were expressed rarely in tumors except in gastroenteropancreatic tumors (38%), meningiomas (30%), and some ...
  https://www.wikigenes.org/e/mesh/e/5011.html
*  Concentration and Activity of Lapatinib in Vestibular Schwannomas - Full Text View - ClinicalTrials.gov
Tumors can grow on the auditory nerves and can cause hearing loss. A common type of tumor that does this is a vestibular ... Neurofibromatoses. Neurofibroma. Neuroma. Neurilemmoma. Neuroma, Acoustic. Neurofibromatosis 2. Nerve Sheath Neoplasms. ... These tumors cause unilateral hearing loss, tinnitus, and vertigo. The primary treatment modality for these tumors is surgical ... Neuroendocrine Tumors. Neuroectodermal Tumors. Neoplasms, Germ Cell and Embryonal. Cranial Nerve Neoplasms. Neoplasms by Site. ...
  https://clinicaltrials.gov/show/NCT00863122
*  PTC299 for Treatment of Neurofibromatosis Type 2 - Full Text View - ClinicalTrials.gov
Formation of new blood vessels (angiogenesis) is important for tumor growth in neurofibromatosis type 2 (NF2). It is known that ... Neurofibromatoses. Neurofibromatosis 1. Neurofibroma. Neurofibromatosis 2. Nerve Sheath Neoplasms. Neoplasms, Nerve Tissue. ... Neuroendocrine Tumors. Neuroectodermal Tumors. Neoplasms, Germ Cell and Embryonal. Neuroma. Vestibulocochlear Nerve Diseases. ... Genetics Home Reference related topics: Neurofibromatosis type 1 Neurofibromatosis type 2 MedlinePlus related topics: ...
  https://clinicaltrials.gov/ct2/show/NCT00911248?term=Barth+Syndrome&rank=6
*  Neurofibromatosis Type 2 Workup: Approach Considerations, Genetic Studies, Imaging Studies
... is a genetic disorder marked by the predisposition to develop a variety of tumors of the central and peripheral nervous systems ... In contrast to neurofibromatosis type 1 (NF1), NF2 produces a paucity of cutaneous manifestations. ... Unlike the tumors associated with neurofibromatosis type 1 (NF1), those found in NF2 are usually made up of 1 of 3 cell types- ... encoded search term (Neurofibromatosis%20Type%202) and Neurofibromatosis Type 2 What to Read Next on Medscape. Medscape Consult ...
  https://emedicine.medscape.com/article/1178283-workup
*  SPTBN1 - Wikipedia
Robb VA, Li W, Gascard P, Perry A, Mohandas N, Gutmann DH (2003). "Identification of a third Protein 4.1 tumor suppressor, ... Neill GW, Crompton MR (2001). "Binding of the merlin-I product of the neurofibromatosis type 2 tumour suppressor gene to a ... Scoles DR, Huynh DP, Morcos PA, Coulsell ER, Robinson NG, Tamanoi F, Pulst SM (1998). "Neurofibromatosis 2 tumour suppressor ... "Binding of the merlin-I product of the neurofibromatosis type 2 tumour suppressor gene to a novel site in beta-fodrin is ...
  https://en.wikipedia.org/wiki/SPTBN1
*  Similar articles for PubMed (Select 12695331) - PubMed - NCBI
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors. ... Neurofibromatosis 2 tumor suppressor protein colocalizes with ezrin and CD44 and associates with actin-containing cytoskeleton. ... The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.. Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, ... Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells. ...
  https://www.ncbi.nlm.nih.gov/pubmed?LinkName=pubmed_pubmed&from_uid=12695331
*  Metastatic Meningioma of the Scalp | Cutis
... expanding intracranial lesions and are the most common benign intracranial tumor in adults.1 Rarely, meningioma e ... The patient's son died from a brain tumor, but the exact tumor type and age at the time of death were unknown. Her current ... Molecular genetics of neurofibromatosis 2 and related tumors (acoustic neuromas and meningioma). Ann N Y Acad Sci. 1991;615:338 ... In children, a broad differential diagnosis should be considered, including dermoid and epidermoid tumors, dermal sinus tumors ...
  https://www.mdedge.com/cutis/article/164919/nonmelanoma-skin-cancer/metastatic-meningioma-scalp
*  Publications | Erez
Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 1. Clinical Cancer Research, 23(000055357): ... Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders. Clinical Cancer ...
  http://www.weizmann.ac.il/Biological_Regulation/Erez/publications