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*  Frontiers | The Nucleotide Excision Repair Pathway Protects Borrelia burgdorferi from Nitrosative Stress in Ixodes scapularis...
... a coenzyme A disulfide reductase (cdr), thioredoxin/thioredoxin reductase (trxA/trxB), and the neutrophil activating protein A ... burgdorferi include thioredoxin/thioredoxin reductase (trxA/trxB), methionine disulfide reductase (bb0340), and napA (bicA/dpsA ... 2011). The coenzyme A disulphide reductase of Borrelia burgdorferi is important for rapid growth throughout the enzootic cycle ... 2006). Borrelia burgdorferi bb0728 encodes a coenzyme A disulphide reductase whose function suggests a role in intracellular ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2016.01397/full
*  Disulfide oxidoreductase D - Wikipedia
... thioredoxin reductase (TrxB; present in the cytoplasm), thioredoxin (TrxA; also in the cytoplasm), DsbD (the integral membrane ... Cho, Seung-Hyun; Beckwith, Jon (2006). "Mutations of the membrane-bound disulfide reductase DsbD that block electron transfer ... DsbD contains three cysteine pairs that undergo reversible disulfide rearrangements. TrxA donates electrons to the ... reversibly forming two disulfide bonds. Although DsbA displays no proofreading activity for repair of wrongly paired disulfides ...
  https://en.wikipedia.org/wiki/Disulfide_oxidoreductase_D
*  Frontiers | Proteomics Analysis Revealed that Crosstalk between Helicobacter pylori and Streptococcus mitis May Enhance...
TrxA) and other redox-regulating enzymes of H. pylori were less abundant in co-culture possibly suggesting reduced oxidative ... regulation of the Staphylococcus aureus thioredoxin and thioredoxin reductase genes in response to oxygen and disulfide stress ... The expression of thioredoxin (TrxA), a small redox-regulating protein that is involved in maintaining the thiol/ disulfide ... On the other hand, thioredoxin (TrxA) and other redox-regulating enzymes of H. pylori were less abundant in co-culture possibly ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2016.01462/full
*  Oxidation response - Wikipedia
This occurs in the following steps: (i) thioredoxin reductase transfers electrons from NADPH to thioredoxin via a flavin ... The main nonenzymatic antioxidants in E. coli are GSH and thioredoxin (encoded by trxA). Ubiquinone and menaquinone may also ... protein disulfide isomerase facilitates disulfide exchange reactions with large inactive protein substrates, besides having ... glutathione reductase), grxA (glutaredoxin 1), trxC(thioredoxin 2), ahpCF (alkyl hydroperoxide reductase), dps (nonspecific DNA ...
  https://en.wikipedia.org/wiki/Oxidation_response
*  glgB protein (Synechocystis sp. PCC6803) - STRING interaction network
trxA. Thioredoxin; Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through ... the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (107 aa ...
  https://string-db.org/network/1148.SYNGTS_2110
*  Protocols and Video Articles Authored by Ursula Jakob (Translated to Spanish)
TrxA and Trx2. Both thioredoxins are capable of reducing disulfide bonds using a conserved pair of cysteine residues present in ... The zinc-free protein conserves its reductase activity. Altogether, our results suggest that the zinc center might play the ... Not Every Disulfide Lasts Forever: Disulfide Bond Formation As a Redox Switch Antioxidants & Redox Signaling. Aug, 2003 , ... Jun, 2013 , Pubmed ID: 23585533 Formation of nonnative disulfide bonds in the cytoplasm, so-called disulfide stress, is an ...
  https://www.jove.com/author/Ursula_Jakob?language=Spanish
*  The use of proteomic techniques to study the physiology and virulence of staphylococcus aureus
SACOL1377 146 thioredoxin disulfide reductase (trxB) SACOL0829 146 pyruvate kinase (pyk) SACOL1745 143 antibacterial protein ( ... putative SACOL1762 1 thioredoxin (trxA) SACOL1155 1 translation initiation factor IF 2 (infB) SACOL1288 1 Dps family protein ... SACOL1070 32 pyruvate oxidase SACOL2553 32 thioredoxin, putative SACOL0875 32 coenzyme A disulfide reductase SACOL0975 32 ... Continued) Thioredoxin reductase P99101,TRXB Ref No Values 7.7 Value Missing No Values 7.7 Putative dipeptidase SA1572 Q7A522, ...
  http://digital.lib.usf.edu/SFS0028061/00001
*  Interactions of glutaredoxins, ribonucleotide reductase, and components of the DNA replication system of Escherichia coli | PNAS
The dnaAN locus is responsible for the restoration of disulfide bond reduction in a trxA, trxC, grxA, nrdH strain. The RO36 ... thioredoxin 1, and thioredoxin 2 are each capable of reducing the essential enzyme ribonucleotide reductase to regenerate its ... thioredoxin 1 can maintain methionine-sulfoxide reductase in the reduced state, whereas thioredoxin 2, when expressed at levels ... Model of electron flow in trxA, trxC, grxA, nrdH suppressor strains. Arrows represent the path of reduction of disulfide bonds ...
  http://www.pnas.org/content/101/19/7439.full
*  Thioredoxins Summary Report | CureHunter
The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE. ... Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. ... Thioredoxins: Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide ... The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE. ...
  http://www.curehunter.com/public/keywordSummaryD013879-Thioredoxins.do
*  What Lies Beyond Uranus?: Preconceptions, Ignorance, Serendipity and Suppressors in the Search for Biology's Secrets | Genetics
... since thioredoxin reductase reduces the disulfide bond of thioredoxin, which, in turn, reduces the disulfide bonds of certain ... 1998). In contrast, simply eliminating thioredoxins 1 and 2 in a trxA, trxC double mutant did not give active cytoplasmic AP, ... missing both glutathione reductase and thioredoxin reductase, eliminating both major pathways for the reduction of disulfide ... disulfide-bonded) thioredoxins in the cytoplasm. These oxidized thioredoxins can now promote disulfide bond formation in ...
  http://www.genetics.org/content/176/2/733
*  Cloning and functional characterization of thiol disulfide interchange system proteins from Staphylococcus aureus
The substrate promiscuity of the thioredoxin system proteins of S. aureus, TrxB and TrxA, was demonstrated through their ... This study had two major aims: the functional characterisation of the MerA and YpdA flavin disulfide reductase homologs, and ... While failing to show demonstrable disulfide reductase activity, MerA instead was found to have the ability to reduce two ... Die substraat-promiskuïteit van die thioredoxin-sisteem proteïene van S. aureus, TrxB en TrxA, is gedemonstreer deur die ...
  http://scholar.sun.ac.za/handle/10019.1/95479
*  SUN 1858 protein (Sulfurovum sp. NBC371) - STRING interaction network
Thioredoxin. Peptide-methionine (S)-S-oxide reductase (EC-1.8.4.11); Has an important function as a repair enzyme for proteins ... Redox-active disulfide protein 2. Peptide-methionine (S)-S-oxide reductase (EC-1.8.4.11); Has an important function as a repair ... Thioredoxin. Peptide-methionine (S)-S-oxide reductase (EC-1.8.4.11); Has an important function as a repair enzyme for proteins ... Thioredoxin. Peptide-methionine (S)-S-oxide reductase (EC-1.8.4.11); Has an important function as a repair enzyme for proteins ...
  https://string-db.org/network/387093.SUN_1858
*  SISIUS: Ficha personal: Francisco Javier Florencio Bellido
Selecting Thioredoxins for Disulphide Proteomics: Target Proteomes of Three Thioredoxins from the Cyanobacterium Synechocystis ... Exploring a Putative Nadp-Thioredoxin-Reductase/Thioredoxin System in Cyanobacteria. Poster en Congreso. Seminars on Proteomics ... Electron Transport Controls Transcription of the Thioredoxin Gene (Trxa) in the Cyanobacterium Synechocystis Sp PCC 6803. En: ... NADPH-Thioredoxin Reductase C Mediates the Response to Oxidative Stress and Thermotolerance in the Cyanobacterium Anabaena sp. ...
  http://investigacion.us.es/sisius/sis_showpub.php?idpers=651
*  ECMDB: Hydrogen peroxide (ECMDB21232) (M2MDB001640)
Efficient electron donor for the essential enzyme ribonucleotide reductase. Is also able to reduce the interchain disulfide ... Hydrogen peroxide + Reduced Thioredoxin ,2 Water + Oxidized Thioredoxin. 2 Hydrogen peroxide ,,2 Water + Oxygen. 2 Hydrogen ion ... trxA. Uniprot ID:. P0AA25 Molecular weight:. 11807. Protein Details. 21. Pyridoxine/pyridoxamine 5'-phosphate oxidase ... Thioredoxin-1. General function:. Involved in electron carrier activity. Specific function:. Participates in various redox ...
  http://ecmdb.ca/compounds/ECMDB21232
*  Biopharmaceutical Expression Systems and Genetic Engineering Technologies
148 Bacillus subtilis, super-oxidizing strains; Thiol-disulfide oxidoreductases (TDORs); Thioredoxin A (TrxA) depletion - ... 235 CHO DG44 cells, DHFR-; CHO-DG44; DUK-XB11; CHO K1 DUX B11 (DHFR-) cells; Dhydrofolate reductase selecton/amplfcaton, CHO ... 221 Dhydrofolate reductase (DHFR) System - selectable marker/amplfcaton; CHO and NS0 cells ... 253 Cholesterol/3-ketosterod reductase (p3-KSR) expresson - cholesterol selecton/nducton of NS0 cells ...
  http://www.mtbeurope.info/bi/reports/biopharmaceutical_expression_systems.htm
*  Network Portal - Gene BSU11500
trxA. thioredoxin (RefSeq). 77, 259. BSU29540. ppnK. inorganic polyphosphate/ATP-NAD kinase (RefSeq). 77, 359. ... Arsenate reductase and related proteins, glutaredoxin family. cog/ cog. electron transport. go/ biological_process. arsenate ... reductase (glutaredoxin) activity. go/ molecular_function. electron carrier activity. go/ molecular_function. protein disulfide ...
  http://networks.systemsbiology.net/bsu/gene/BSU11500
*  US Patent # 5,869,445. Methods for eliciting or enhancing reactivity to HER-2/neu protein - Patents.com
While thioredoxin reductase has been reported to stabilize and solubilize other heterologous proteins expressed in E. coli, it ... This cDNA for the trxA-human HER-2/neu polypeptide fusion protein was subcloned into a modified pET expression vector for ... Cysteine residues may be deleted or replaced with other amino acids to prevent formation of incorrect intramolecular disulfide ... For purification of the human HER-2/neu polypeptide with the thioredoxin reductase fusion partner containing the 6XHis affinity ...
  http://patents.com/us-5869445.html
*  Gentaur Molecular :Abfron \ Thioredoxin 1, Yeast, Protein \ LF-P0036
Thioredoxin 1, Yeast, Protein \ LF-P0036 for more molecular products just contact us ... Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Thioredoxin reductase TR3). [PDIA6 ERP5 P5 TXNDC7] Protein disulfide- ... Thioredoxin domain-containing protein 7). [trxA fipA tsnC b3781 JW5856] Thioredoxin 1 (Trx-1). [PRDX4] Peroxiredoxin-4 (EC 1.11 ... Txnrd3 Tgr Trxr3] Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase TR2). [ ...
  http://www.antibody-antibodies.com/product_det.php?id=3045897&supplier=search&name=Thioredoxin%201,%20Yeast,%20Protein
*  REDUCED GENOME E. COLI - Patent application
0073] The recombinant protein may also be co-expressed with chaperones/disulfide-bond forming enzymes which may provide proper ... 3963784 3964113 trxA b3781 CDS + 3964254 3964355 rhoL b3782 CDS + 3964440 3965699 rho b3783 CDS + 3965939 3967042 rfe b3784 CDS ... reductase MDS56 CDS complement(4491398 . . . 4492429) idnD b4267 L-idonate dehydrogenase MDS56 CDS 4492646 . . . 4493209 idnK ... thioredoxin-like protein MDS60 CDS complement(517564 . . . 518373) ybbO b0493 putative oxidoreductase MDS60 CDS complement( ...
  http://www.patentsencyclopedia.com/app/20130011874
*  Essential Bacillus subtilis genes | PNAS
... which encode thioredoxin and thioredoxin reductase with the respiration genes, because of the role of TrxA in electron ... Modulation of Thiol-Disulfide Oxidoreductases for Increased Production of Disulfide-Bond-Containing Proteins in Bacillus ... Bacillus anthracis Thioredoxin Systems, Characterization and Role as Electron Donors for Ribonucleotide Reductase ... 16, which is published as supporting information on the PNAS web site). One, dfrA, codes for dihydrofolate reductase, which ...
  http://www.pnas.org/content/100/8/4678