Viruses | Free Full-Text | HCMV Infection of Human Trophoblast Progenitor Cells of the Placenta Is Neutralized by a Human...
Human trophoblast progenitor cells (TBPCs) give rise to the mature cell types of the chorionic villi, CTBs and multi-nucleated ... Our results indicate that mAbs to gB protect trophoblast progenitors of the placenta and could be included in antibody ... TBPC expression of markers for trophoblasts (CK7), stem cell self-renewal (HMGA2) and trophoblast fate acquisition (GATA-4 and ... Human trophoblast progenitor cells (TBPCs) give rise to the mature cell types of the chorionic villi, CTBs and multi-nucleated ...http://www.mdpi.com/1999-4915/6/3/1346/htm
Novel regulators of trophoblast stem cell potential * An Evolutionary Approach to Understanding Transcriptional Control in the ... Microfluidic devices for the study of human trophoblast invasion * Manipulating epigenetic reprogramming in vivo and its role ... 2017) A microfluidics assay to study invasion of human placental trophoblast cells. J R Soc Interface. May;14(130). pii: ... 2017) Mitochondrial - Endoplasmic reticulum interactions in the trophoblast: Stress and senescence. Placenta. 52:146-155. doi: ...https://www.trophoblast.cam.ac.uk/publications
The Mrj co-chaperone mediates keratin turnover and prevents the formation of toxic inclusion bodies in trophoblast cells of the...
3A). Trophoblast stem (TS) cell cultures are an established model for studying chorionic trophoblast cells in vitro (Tanaka et ... 3D). These data indicate that Mrj mutant chorionic trophoblast cells show the same type of keratin defects as trophoblast giant ... We have shown here that both Mrj-deficient trophoblast giant cells and chorionic trophoblast cells lack a normal keratin ... in wild-type trophoblast giant cells in vitro. (B) K18 expression (green) in trophoblast giant cells cultured with (right) or ...http://dev.biologists.org/content/134/9/1809
"Transforming Growth Factor-Beta Induces Differentiation of the Labyrin" by Kaisa Selesniemi, Meredith A. Reedy et al.
In rodents, labyrinthine trophoblasts of the placenta are especially important, because they are capable of differentiating ... In this study, we investigated the effects of TGF-β on the differentiation of the labyrinthine trophoblast stem cell lines SM10 ... In contrast, TGF-β induced the expression of a marker of differentiated labyrinthine trophoblasts, Gcm1, only in the SM10 cell ... Even though the molecular signals triggering labyrinthine trophoblast differentiation are poorly understood, transforming ...https://corescholar.libraries.wright.edu/ncbp/33/
CACHE . Linker-Scanning Mutational Analysis of Tanscriptional Activity of the Human Immunodeficiency Virus Type 1 Long Terminal...
The virus collects in the placental trophoblast, and only certain strains are able to pass from that point into the fetal blood ... By transfecting the mutated LTR's into human placental trophoblasts, it is possible to analyze the transcriptional activity of ... JAR cells are analogous to first trimester trophoblast, and are used for comparison purposes. Time constraints considered, it ... This report analyzes transcription factors present in placental trophoblast which may be critically important to HIV ...https://cache.kzoo.edu/handle/10920/24969
The release of 15-hydroxyeicosatetraenoic acid by human placental trophoblast is increased in preeclampsia.
... and its level is elevated in trophoblast from preeclamptic women compared with normal. We also used selective enzymatic ... We tested the hypothesis that trophoblast produces 15-hydroxyeicosatetraenoic acid, ... OBJECTIVE: We tested the hypothesis that trophoblast produces 15-hydroxyeicosatetraenoic acid, and its level is elevated in ... CONCLUSIONS: The data indicate that 15-hydroxyeicosatetraenoic acid is produced in trophoblasts and its release by ...http://www.biomedsearch.com/nih/release-15-hydroxyeicosatetraenoic-acid-by/9465803.html
Cytotrophoblast - Wikipedia
Conversely, if there is too much invasion of uterine tissue by the trophoblast then a hydatidiform mole or choriocarcinoma may ... The cytotrophoblast (or layer of Langhans) is the inner layer of the trophoblast. It is interior to the syncytiotrophoblast and ... Dakour, J., Li, H., Chen, H., & Morrish, D. W. (1999). "EGF promotes development of a differentiated trophoblast phenotype ... Once they make contact the trophoblast begins to rapidly proliferate. The cytotrophoblast secretes proteolytic enzymes to break ...https://en.wikipedia.org/wiki/Cytotrophoblast
Fluid Shear Stress Promotes Placental Growth Factor Upregulation in Human Syncytiotrophoblast Through the cAMP-PKA Signaling...
trophoblast. Introduction. During pregnancy, the syncytiotrophoblast is the main source of placental growth factor (PlGF).1 ... cAMP is known to be a strong activator of PlGF gene expression in human trophoblasts, and this effect is mediated through ... cAMP is known to be a strong activator of PlGF gene expression in human trophoblasts, and this effect is mediated through ... Relative decreases on oxygen tension decrease PlGF expression in trophoblast13 but increase PlGF expression in other cell types ...http://hypertensionaha.smart01.highwire.org/content/68/6/1438
Importance of matrix metalloproteinases in human trophoblast invasion. - The Kennedy Institute of Rheumatology
Importance of matrix metalloproteinases in human trophoblast invasion. Bischof P., Martelli M., Campana A., Itoh Y., Ogata Y., ...https://www.kennedy.ox.ac.uk/publications/411406
Trophoblast - Wikipedia
This layer of trophoblasts is also collectively referred to as "the trophoblast", or, after gastrulation, the trophectoderm, as ... The invasion of a specific type of trophoblast (extravillous trophoblast) into the maternal uterus is a vital stage in the ... cytotrophoblast in the tips of villi can differentiate into another type of trophoblast called the extravillous trophoblast. ... Failure of the trophoblast to invade sufficiently is important in the development of some cases of pre-eclampsia. Too firm an ...https://en.wikipedia.org/wiki/Trophoblast
Hypoxia alters the epigenetic profile in cultured human placental trophoblasts. - PubMed - NCBI
Hypoxia alters the epigenetic profile in cultured human placental trophoblasts.. Yuen RK1, Chen B, Blair JD, Robinson WP, ... Figure 1. Cell culture condition for placental trophoblast samples. Cell cultures were plated and maintained in a culture ... We hypothesized that oxygen tension affects villous trophoblast by modulation of gene expression through DNA methylation. We ... a condition displaying altered development of placental trophoblast. ...https://www.ncbi.nlm.nih.gov/pubmed/23314690
Utilization of Trophoblast for Early Prenatal Diagnosis | SpringerLink
Davis, M. E., 1959, Trophoblast in the circulating blood during pregnancy, Am. J. Obstet. Gynecol. 78:970.Google Scholar ... Raafat, M., Brayton, J. B., Apgar, V., et al., 1975, A new approach to prenatal diagnosis using trophoblast cells in the ... Rhine S.A., Milunsky A. (1979) Utilization of Trophoblast for Early Prenatal Diagnosis. In: Milunsky A. (eds) Genetic Disorders ...https://link.springer.com/chapter/10.1007/978-1-4684-3438-5_13
Peroxisome proliferator-activated receptors of trophoblast cells in miscarriage.
... in cells of the villous and extravillous trophoblasts in missed abortion.. ...http://www.biomedsearch.com/nih/Peroxisome-proliferator-activated-receptors-trophoblast/22803185.html
Immunobiology of Human Trophoblast | Springer for Research & Development
Human Chorionic Gonadotropin Trophoblast Cell Chorionic Villus Extravillous Trophoblast Human Trophoblast These keywords were ... Hsi B-L: Immunobiology of human trophoblast membrane antigens, in Loke YW, Whyte A (eds): Biology of Trophoblast, Amsterdam, ... Contractor SF: Metabolic and enzymatic activity of human trophoblast, Loke YW, Whyte A (eds): Biology of Trophoblast. Amsterdam ... Kurman RJ, Main CS, Chen H-C: Intermediate trophoblast: a distinctive form of trophoblast with specific morphological, ...https://rd.springer.com/chapter/10.1007/978-1-4612-3746-4_12
Trophoblast cell financial definition of trophoblast cell
What is trophoblast cell? Meaning of trophoblast cell as a finance term. What does trophoblast cell mean in finance? ... Definition of trophoblast cell in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... Trophoblast cell financial definition of trophoblast cell https://financial-dictionary.thefreedictionary.com/trophoblast+cell ... redirected from trophoblast cell). Also found in: Dictionary, Thesaurus, Medical, Legal, Encyclopedia. cell. an independent ...http://financial-dictionary.thefreedictionary.com/trophoblast+cell
Trophoblast glycoprotein (TPBG) antibody | acris-antibodies.com
Trophoblast glycoprotein (TPBG) (Extracell. Dom.) antibody. Not available. Sheep. IgG. Aff - Purified. Ms. E, F, ICC/IF, WB. ... Recombinant protein of human trophoblast glycoprotein (TPBG). Human. > 80 % Preparation: Recombint protein was captured through ... Background of Trophoblast glycoprotein (TPBG) antibody. Kit Component:. - KN318077G1, Tpbg gRNA vector 1 in pCas-Guide vector. ... Lenti ORF particles, Tpbg (Myc-DDK-tagged ORF) - Rat trophoblast glycoprotein (Tpbg), 200 uL, ,10^7 TU/mL. Not available. ...https://www.acris-antibodies.com/target/trophoblast-glycoprotein-tpbg-antibody.htm
Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface | Science
Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface Message Subject. (Your Name) has forwarded a page to ... Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface. By Olga D. Genbacev, Akraporn Prakobphol, Russell A. ... Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface. By Olga D. Genbacev, Akraporn Prakobphol, Russell A. ... Trophoblast adhesion to the uterine wall is the requisite first step of implantation and, subsequently, placentation. At the ...http://science.sciencemag.org/content/299/5605/405
Int J Dev Biol - Split immunological tolerance to trophoblast
Taken together, these results strengthen the evidence for a state of split tolerance to trophoblast, and furthermore define ... Split immunological tolerance to trophoblast Amanda de Mestre1, Leela Noronha2, Bettina Wagner3 and Douglas F. Antczak*,2 ... trophoblast, pregnancy, tolerance, cytokine, lymphocyte. *Corresponding author e-mail: firstname.lastname@example.org ... Taken together, these results strengthen the evidence for a state of split tolerance to trophoblast, and furthermore define ...http://www.ijdb.ehu.es/web/paper/082795ad/split-immunological-tolerance-to-trophoblast-
Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway. -...
The trophoblast cells were positive β2GPI.. B) First trimester trophoblast cells (HTR8) were assessed for ID2 and IIC5 binding ... First trimester trophoblast cells (HTR8) were incubated with no treatment (NT) or the CM from trophoblast cells treated with NT ... C) Trophoblast cells (HTR8) were transiently transfected to express the MyD88-DN. Following transfection, trophoblast cells ... Barcharts shows (A) the differences in trophoblast cell death; and (B) the differences in trophoblast caspase-3 activity, ...https://www.ncbi.nlm.nih.gov/pubmed?term=19614626
TGF-β1 up-regulates connexin43 expression: a potential mechanism for human trophoblast cell differentiation. | Sigma-Aldrich
We showed that treatment with TGF-β1 increased Cx43 expression and GJIC in HTR-8/SVneo human trophoblast cells. In addition, ... These results provide evidence that Cx43 and GJIC activity are up-regulated by TGF-β1 in human trophoblast cells, which ... TGF-β1 up-regulates connexin43 expression: a potential mechanism for human trophoblast cell differentiation.. [Jung-Chien Cheng ... To date, whether Cx43 mediates TGF-β1-induced trophoblast differentiation has not been determined. ...https://www.sigmaaldrich.com/catalog/papers/25560303
Estrogen-enhanced apical and basolateral secretion of apolipoprotein B-100 by polarized trophoblast-derived BeWo cells.
Gene expression profile in human trophoblast and gestational trophoblastic disease - OpenThesis
The genes regulated by TGF? (a common cytokine at the implantation site) in invasive extravillous trophoblast were examined in ... Neoplastic transformation of trophoblast leads to gestational trophoblastic diseases (GTD). Choriocarcinoma (CCA) and ... Uncorrected OCR) Abstract of thesis entitled GENE EXPRESSION PROFILE IN HUMAN TROPHOBLAST AND GESTATIONAL TROPHOBLASTIC DISEASE ... Gene expression profile in human trophoblast and gestational trophoblastic disease. by Feng, Huichen ...http://www.openthesis.org/documents/Gene-expression-profile-in-human-513980.html
The emerging roles of placenta-specific microRNAs in regulating trophoblast proliferation during the first trimester.
In situ hybridisation analysis showed that miR-517b and miR-519a were located primarily in the trophoblast layer, while miR- ... These findings suggest that miR-517b and miR-519a may play an important role in trophoblast proliferation during the first ... Immunohistochemical analyses indicated that placental trophoblast proliferation ability was associated with the weight of villi ... 1283 were expressed not only in the villous trophoblasts but also in some villous stroma cells. ...http://www.biomedsearch.com/nih/emerging-roles-placenta-specific-microRNAs/23046105.html