Viruses | Free Full-Text | HCMV Infection of Human Trophoblast Progenitor Cells of the Placenta Is Neutralized by a Human...
Human trophoblast progenitor cells (TBPCs) give rise to the mature cell types of the chorionic villi, CTBs and multi-nucleated ... Our results indicate that mAbs to gB protect trophoblast progenitors of the placenta and could be included in antibody ... TBPC expression of markers for trophoblasts (CK7), stem cell self-renewal (HMGA2) and trophoblast fate acquisition (GATA-4 and ... Human trophoblast progenitor cells (TBPCs) give rise to the mature cell types of the chorionic villi, CTBs and multi-nucleated ...http://www.mdpi.com/1999-4915/6/3/1346/htm
Novel regulators of trophoblast stem cell potential * An Evolutionary Approach to Understanding Transcriptional Control in the ... Microfluidic devices for the study of human trophoblast invasion * Manipulating epigenetic reprogramming in vivo and its role ... 2017) A microfluidics assay to study invasion of human placental trophoblast cells. J R Soc Interface. May;14(130). pii: ... 2017) Mitochondrial - Endoplasmic reticulum interactions in the trophoblast: Stress and senescence. Placenta. 52:146-155. doi: ...https://www.trophoblast.cam.ac.uk/publications
The Mrj co-chaperone mediates keratin turnover and prevents the formation of toxic inclusion bodies in trophoblast cells of the...
3A). Trophoblast stem (TS) cell cultures are an established model for studying chorionic trophoblast cells in vitro (Tanaka et ... 3D). These data indicate that Mrj mutant chorionic trophoblast cells show the same type of keratin defects as trophoblast giant ... We have shown here that both Mrj-deficient trophoblast giant cells and chorionic trophoblast cells lack a normal keratin ... in wild-type trophoblast giant cells in vitro. (B) K18 expression (green) in trophoblast giant cells cultured with (right) or ...http://dev.biologists.org/content/134/9/1809
"Transforming Growth Factor-Beta Induces Differentiation of the Labyrin" by Kaisa Selesniemi, Meredith A. Reedy et al.
In rodents, labyrinthine trophoblasts of the placenta are especially important, because they are capable of differentiating ... In this study, we investigated the effects of TGF-β on the differentiation of the labyrinthine trophoblast stem cell lines SM10 ... In contrast, TGF-β induced the expression of a marker of differentiated labyrinthine trophoblasts, Gcm1, only in the SM10 cell ... Even though the molecular signals triggering labyrinthine trophoblast differentiation are poorly understood, transforming ...https://corescholar.libraries.wright.edu/ncbp/33/
CACHE . Linker-Scanning Mutational Analysis of Tanscriptional Activity of the Human Immunodeficiency Virus Type 1 Long Terminal...
The virus collects in the placental trophoblast, and only certain strains are able to pass from that point into the fetal blood ... By transfecting the mutated LTR's into human placental trophoblasts, it is possible to analyze the transcriptional activity of ... JAR cells are analogous to first trimester trophoblast, and are used for comparison purposes. Time constraints considered, it ... This report analyzes transcription factors present in placental trophoblast which may be critically important to HIV ...https://cache.kzoo.edu/handle/10920/24969
The release of 15-hydroxyeicosatetraenoic acid by human placental trophoblast is increased in preeclampsia.
... and its level is elevated in trophoblast from preeclamptic women compared with normal. We also used selective enzymatic ... We tested the hypothesis that trophoblast produces 15-hydroxyeicosatetraenoic acid, ... OBJECTIVE: We tested the hypothesis that trophoblast produces 15-hydroxyeicosatetraenoic acid, and its level is elevated in ... CONCLUSIONS: The data indicate that 15-hydroxyeicosatetraenoic acid is produced in trophoblasts and its release by ...http://www.biomedsearch.com/nih/release-15-hydroxyeicosatetraenoic-acid-by/9465803.html
Is this the pathophysiology of preeclampsia? - Welcome to the Preeclampsia Foundation
"The invading placental trophoblast cells intermingle with maternal immune cells in the uterine lining. Trophoblast express not ... In the first trimester of pregnancy, a subpopulation of fetal trophoblast cells, the extravillous trophoblast, invade the ... Fewer trophoblast cells are present within the spiral arterioles, and the vessel walls remain stiff (Khong et al., 1986; ... Evidence that the invading placental trophoblast cells express HLA (Human Leukocyte Antigen) family known as HLA-C. - Evidence ...http://preeclampsia.org/forum/viewtopic.php?p=345826
Cytotrophoblast - Wikipedia
Conversely, if there is too much invasion of uterine tissue by the trophoblast then a hydatidiform mole or choriocarcinoma may ... The cytotrophoblast (or layer of Langhans) is the inner layer of the trophoblast. It is interior to the syncytiotrophoblast and ... Dakour, J., Li, H., Chen, H., & Morrish, D. W. (1999). "EGF promotes development of a differentiated trophoblast phenotype ... Once they make contact the trophoblast begins to rapidly proliferate. The cytotrophoblast secretes proteolytic enzymes to break ...https://en.wikipedia.org/wiki/Cytotrophoblast
Fluid Shear Stress Promotes Placental Growth Factor Upregulation in Human Syncytiotrophoblast Through the cAMP-PKA Signaling...
trophoblast. Introduction. During pregnancy, the syncytiotrophoblast is the main source of placental growth factor (PlGF).1 ... cAMP is known to be a strong activator of PlGF gene expression in human trophoblasts, and this effect is mediated through ... cAMP is known to be a strong activator of PlGF gene expression in human trophoblasts, and this effect is mediated through ... Relative decreases on oxygen tension decrease PlGF expression in trophoblast13 but increase PlGF expression in other cell types ...http://hypertensionaha.smart01.highwire.org/content/68/6/1438
Importance of matrix metalloproteinases in human trophoblast invasion. - The Kennedy Institute of Rheumatology
Importance of matrix metalloproteinases in human trophoblast invasion. Bischof P., Martelli M., Campana A., Itoh Y., Ogata Y., ...https://www.kennedy.ox.ac.uk/publications/411406
Trophoblast - Wikipedia
This layer of trophoblasts is also collectively referred to as "the trophoblast", or, after gastrulation, the trophectoderm, as ... The invasion of a specific type of trophoblast (extravillous trophoblast) into the maternal uterus is a vital stage in the ... cytotrophoblast in the tips of villi can differentiate into another type of trophoblast called the extravillous trophoblast. ... Failure of the trophoblast to invade sufficiently is important in the development of some cases of pre-eclampsia. Too firm an ...https://en.wikipedia.org/wiki/Trophoblast
Human placental trophoblasts confer viral resistance to recipient cells | PNAS
Placental trophoblasts confer viral resistance. Elizabeth Delorme-Axford, Rogier B. Donker, Jean-Francois Mouillet, Tianjiao ... Placental trophoblasts confer viral resistance. Elizabeth Delorme-Axford, Rogier B. Donker, Jean-Francois Mouillet, Tianjiao ... Human placental trophoblasts confer viral resistance to recipient cells Message Subject (Your Name) has sent you a message from ... 2012) The expression profile of C19MC microRNAs in primary human trophoblast cells and exosomes. Mol Hum Reprod 18(8):417-424, ...http://www.pnas.org/content/110/29/12048.full
Hypoxia alters the epigenetic profile in cultured human placental trophoblasts. - PubMed - NCBI
Hypoxia alters the epigenetic profile in cultured human placental trophoblasts.. Yuen RK1, Chen B, Blair JD, Robinson WP, ... Figure 1. Cell culture condition for placental trophoblast samples. Cell cultures were plated and maintained in a culture ... We hypothesized that oxygen tension affects villous trophoblast by modulation of gene expression through DNA methylation. We ... a condition displaying altered development of placental trophoblast. ...https://www.ncbi.nlm.nih.gov/pubmed/23314690
Utilization of Trophoblast for Early Prenatal Diagnosis | SpringerLink
Davis, M. E., 1959, Trophoblast in the circulating blood during pregnancy, Am. J. Obstet. Gynecol. 78:970.Google Scholar ... Raafat, M., Brayton, J. B., Apgar, V., et al., 1975, A new approach to prenatal diagnosis using trophoblast cells in the ... Rhine S.A., Milunsky A. (1979) Utilization of Trophoblast for Early Prenatal Diagnosis. In: Milunsky A. (eds) Genetic Disorders ...https://link.springer.com/chapter/10.1007/978-1-4684-3438-5_13
Knockdown of Heparanase Suppresses Invasion of Human Trophoblasts by Activating p38 MAPK Signaling Pathway
... degradation-related proteins are expressed by extravillous trophoblasts (EVTs) to ensure normal trophoblast invasion . The ... Figure 1: Effect of HPSE on trophoblast cell invasion. 5 × 104 cells were suspended in 100 μl of FBS-free RPMI-1640 medium and ... Figure 2: Effect of HPSE on trophoblast cell tube formation. 1 × 104 cells were seeded on μ-slide angiogenesis plates, coated ... thought that trophoblast-derived heparanase was not required for invasion . The cell lines they used were human first- ...https://www.hindawi.com/journals/dm/2018/7413027/
Establishment and Characterization of a Telomerase-Immortalized Sheep Trophoblast Cell Line
... Yufei Zhang,1 Jing Shi,1 and ... Yufei Zhang, Jing Shi, and Shuying Liu, "Establishment and Characterization of a Telomerase-Immortalized Sheep Trophoblast Cell ...https://www.hindawi.com/journals/bmri/2016/5808575/cta/
Peroxisome proliferator-activated receptors of trophoblast cells in miscarriage.
... in cells of the villous and extravillous trophoblasts in missed abortion.. ...http://www.biomedsearch.com/nih/Peroxisome-proliferator-activated-receptors-trophoblast/22803185.html
Immunobiology of Human Trophoblast | Springer for Research & Development
Human Chorionic Gonadotropin Trophoblast Cell Chorionic Villus Extravillous Trophoblast Human Trophoblast These keywords were ... Hsi B-L: Immunobiology of human trophoblast membrane antigens, in Loke YW, Whyte A (eds): Biology of Trophoblast, Amsterdam, ... Contractor SF: Metabolic and enzymatic activity of human trophoblast, Loke YW, Whyte A (eds): Biology of Trophoblast. Amsterdam ... Kurman RJ, Main CS, Chen H-C: Intermediate trophoblast: a distinctive form of trophoblast with specific morphological, ...https://rd.springer.com/chapter/10.1007/978-1-4612-3746-4_12
Trophoblast cell financial definition of trophoblast cell
What is trophoblast cell? Meaning of trophoblast cell as a finance term. What does trophoblast cell mean in finance? ... Definition of trophoblast cell in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... Trophoblast cell financial definition of trophoblast cell https://financial-dictionary.thefreedictionary.com/trophoblast+cell ... redirected from trophoblast cell). Also found in: Dictionary, Thesaurus, Medical, Legal, Encyclopedia. cell. an independent ...http://financial-dictionary.thefreedictionary.com/trophoblast+cell
Trophoblast glycoprotein (TPBG) antibody | acris-antibodies.com
Trophoblast glycoprotein (TPBG) (Extracell. Dom.) antibody. Not available. Sheep. IgG. Aff - Purified. Ms. E, F, ICC/IF, WB. ... Recombinant protein of human trophoblast glycoprotein (TPBG). Human. > 80 % Preparation: Recombint protein was captured through ... Background of Trophoblast glycoprotein (TPBG) antibody. Kit Component:. - KN318077G1, Tpbg gRNA vector 1 in pCas-Guide vector. ... Lenti ORF particles, Tpbg (Myc-DDK-tagged ORF) - Rat trophoblast glycoprotein (Tpbg), 200 uL, ,10^7 TU/mL. Not available. ...https://www.acris-antibodies.com/target/trophoblast-glycoprotein-tpbg-antibody.htm
Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface | Science
Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface Message Subject. (Your Name) has forwarded a page to ... Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface. By Olga D. Genbacev, Akraporn Prakobphol, Russell A. ... Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface. By Olga D. Genbacev, Akraporn Prakobphol, Russell A. ... Trophoblast adhesion to the uterine wall is the requisite first step of implantation and, subsequently, placentation. At the ...http://science.sciencemag.org/content/299/5605/405
Int J Dev Biol - Split immunological tolerance to trophoblast
Taken together, these results strengthen the evidence for a state of split tolerance to trophoblast, and furthermore define ... Split immunological tolerance to trophoblast Amanda de Mestre1, Leela Noronha2, Bettina Wagner3 and Douglas F. Antczak*,2 ... trophoblast, pregnancy, tolerance, cytokine, lymphocyte. *Corresponding author e-mail: firstname.lastname@example.org ... Taken together, these results strengthen the evidence for a state of split tolerance to trophoblast, and furthermore define ...http://www.ijdb.ehu.es/web/paper/082795ad/split-immunological-tolerance-to-trophoblast-
Intermediate trophoblast - Wikipedia
... differentiated from villous intermediate trophoblast The function of the implantation site intermediate trophoblast is to ... differentiated from villous intermediate trophoblast Chorionic-type intermediate trophoblast at chorionic laeve of fetal ... Intermediate trophoblast is a distinct subtype of trophoblastic tissue that arises from the cytotrophoblast. It is sub- ... Intermediate trophoblasts are thought to be the cell of origin for: Exaggerated placental site (EPS): implantation site IT ...https://en.wikipedia.org/wiki/Intermediate_trophoblast