MSC transplantation can be safe, effective approach to treat Crohn's disease-related fistula
MSCs) to achieve a cure and prevent recurrent of Crohn's disease-related fistula can be a safe and effective addition to ... A growing body of clinical evidence shows that transplantation of a patient's own mesenchymal stem cells ( ... A comprehensive review of the latest studies of MSC transplantation for Crohn's fistula and a comparison of MSC versus ... MSC transplantation can be safe, effective approach to treat Crohn's disease-related fistula. *Download PDF Copy ...https://www.news-medical.net/news/20170914/MSC-transplantation-can-be-safe-effective-approach-to-treat-Crohns-disease-related-fistula.aspx
Allogene MSCs Transplantation in Patients With Chronic Liver Diseases Through Peripheral Vein. - Full Text View -...
Allogene MSCs transplantation Allogene MSCs transplantation were performed in patients with chronic liver diseases through ... Allogene MSCs Transplantation in Patients With Chronic Liver Diseases Through Peripheral Vein.. The safety and scientific ... Time Frame: 1-8 weeks after transplantation ]. Secondary Outcome Measures : *Long-term follow-up of Allogene MSCs ... Allogene MSCs transplantation will be performed in patients with chronic liver diseases through peripheral vein and therapeutic ...https://clinicaltrials.gov/ct2/show/NCT01256125?recr=Open&cond=%22Liver+Diseases%22&rank=7
Autologous Mesenchymal Stem Cell (MSC) Transplantation in MS - No Study Results Posted - ClinicalTrials.gov
Autologous Mesenchymal Stem Cell (MSC) Transplantation in MS. The safety and scientific validity of this study is the ...https://clinicaltrials.gov/ct2/show/results/NCT00813969?view=record
Transfusion and Transplantation Sciences MSc/PGDip/PGCert at University of Bristol on FindAMasters.com
MSc, MA, MPhil & MRes courses in the UK & Ireland ... Transfusion and Transplantation Sciences MSc/PGDip/PGCert at ... Visit the Transfusion and Transplantation Sciences MSc/PGDip/PGCert page on the University of Bristol website for more details ... Clinical Transfusion and Transplantation -Transfusion and Transplantation in Practice (two units) -Biostatistics -Research and ... Transfusion and Transplantation Science: -Pathology of Transfusion and Transplantation Science -Provision of Blood, Cells, ...https://www.findamasters.com/masters-degrees/course/transfusion-and-transplantation-sciences-msc-pgdip-pgcert/?i287d6202c5596
MSc Transfusion and Transplantation Sciences | Study at Bristol | University of Bristol
UK/EU: full-time (MSc). £10,700. Overseas: full-time (MSc). £23,000. Channel Islands/IoM: full-time (MSc). £21,250. UK/EU: full ... Postgraduate Certificate in Transfusion and Transplantation Sciences. *Postgraduate Diploma in Transfusion and Transplantation ... A comparison of stem cell mobilisation drugs for stem cell transplantation.. Assessments are designed to teach skills such as ... is one of just two specialist full-time courses in transfusion and transplantation, and is a recommended course at level seven ...http://bristol.ac.uk/study/postgraduate/2019/life-sciences/msc-transfusion-transplantation-sciences/
The History of Co-Transplantation of UC-MSC and CB-HSC into Human Patients | Smart Cells Baby
The History of Co-Transplantation of UC-MSC and CB-HSC into Human Patients. Home » The History of Co-Transplantation of UC-MSC ... primary MSC from the cord tissue rather than expanded MSC. We find that minimally manipulated native MSC from the cord tissue ... These two studies both show that co-transplantation of ex vivo expanded banked UC-MSC together with CB-HSC are safe in human ... In the case of diabetes, our group is exploring co-transplantation of both pancreatic islets and WJ-MSCs in animal models. Our ...https://www.smartcells.com/baby/b/history-co-transplantation-uc-msc-cb-hsc-human-patients/
Intrathecal Transplantation Of Autologous Adipose Tissue Derived MSC in the Patients With Spinal Cord Injury - Full Text View -...
Intrathecal Transplantation Of Autologous Adipose Tissue Derived MSC in the Patients With Spinal Cord Injury. The safety and ... The effect of intrathecal transplantation of autologous adipose tissue derived mesenchymal stem cells in the patients with ... The Effect of Intrathecal Transplantation of Autologous Adipose Tissue Derived Mesenchymal Stem Cells in the Patients With ...https://clinicaltrials.gov/ct2/show/NCT01624779?term=stem+cell+spinal+cord+injury&rank=13
Safety and Immunological Effects of Mesenchymal Stem Cell Transplantation in Patients With Multiple Sclerosis and Amyotrophic...
IMMUNOLOGICAL EFFECTS OF MSC TRANSPLANTATION. To evaluate the in vivo immunoregulatory effects of MSC transplantation, ... demonstrated the immediate in vivo immunomodulating effects of MSCs, starting as early as 4 hours after MSC transplantation and ... Transplantation of MSCs in patients with MS and ALS is a clinically feasible and relatively safe procedure and induces ... NEURORADIOLOGICAL EFFECTS OF MSC TRANSPLANTATION. Magnetic resonance imaging (1.5 T) of the brain and whole spine during the 6- ...http://pubmedcentralcanada.ca/pmcc/articles/PMC3036569/?lang=en-ca
SELECTBIO - Translational Regenerative Medicine Congress 2014 Speaker Biography
MSC Transplantation in Postoperative Liver Failure (POLF). Wednesday, 22 October 2014 at 16:50 ... MSC Transplantation in Postoperative Liver Failure (POLF). Translational Regenerative Medicine Congress 2014 in Leipzig, ... Mesenchymal stem cells (MSC) improved liver regeneration by decreasing apoptosis and increasing proliferation of hepatocytes in ... He finished his graduation in special visceral and transplantation surgery in 2013 and is a dedicated surgeon in the University ...https://selectbiosciences.com/conferences/biographies.aspx?speaker=1289471&conf=trmc2014
Human versus porcine mesenchymal stromal cells: phenotype, differentiation potential, immunomodulation and cardiac improvement...
... showing very few surviving human MSCs after transplantation(A) and at higher magnifications (B-D). MSCs(β1-integrin, green) ... S2 Surviving MSCs at 28 days after transplantation.Representative immunofluorescent picture at 28 days post-MI, ... Cardiac function and remodelling after MSC transplantation. MI was induced and mice received injections of either PBS (n= 5), ... Cardiac geometry and function after MSC transplantation. Animals injected with pMSC and hMSC exhibited less cardiac remodelling ...http://onlinelibrary.wiley.com/doi/10.1111/j.1582-4934.2011.01455.x/full
Association of TNF-α with Impaired Migration Capacity of Mesenchymal Stem Cells in Patients with Systemic Lupus Erythematosus
... transplantation immunology, immune pathology, immunodeficiency, autoimmune diseases, immune disorders, and immunotherapy. ... MSCs transplantation (MSCT) has been shown to be as a powerful strategy in the treatment of refractory and severe SLE patients ... It has been reported that TNF-α could stimulate the production of HGF to regulate human MSCs migration, which was dependent on ... So far, the precise molecular mechanisms of MSCs migration remain largely unknown. TNF-α is one of the major cytokines in ...https://www.hindawi.com/journals/jir/2014/169082/
Search of: Development | Recruiting, Not yet recruiting, Available Studies | 'Primary Ovarian Insufficiency' - List Results -...
Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Women With Primary Ovarian Insufficiency (POI). * ... A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Insufficiency Patients. *Primary ... CRYOPRESERVATION OF OVARIAN TISSUE FOR POTENTIAL IN VITRO MATURATION OR AUTOLOGOUS TRANSPLANTATION ...https://clinicaltrials.gov/ct2/results?term=Development&recrs=abc&cond=%22Primary+Ovarian+Insufficiency%22
Search of: Recruiting, Not yet recruiting, Available Studies | 'Primary Ovarian Insufficiency' - List Results - ClinicalTrials...
Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Women With Primary Ovarian Insufficiency (POI). * ... Autologous Adipose Derived Mesenchymal Stromal Cells Transplantation in Women With Premature Ovarian Failure (POF). *Premature ... A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Insufficiency Patients. *Primary ... CRYOPRESERVATION OF OVARIAN TISSUE FOR POTENTIAL IN VITRO MATURATION OR AUTOLOGOUS TRANSPLANTATION ...https://clinicaltrials.gov/ct2/results?recr=Open&cond=%22Primary+Ovarian+Insufficiency%22&show_rss=Y
Search of: Chromosome Disorders | Recruiting, Not yet recruiting, Available Studies | 'Primary Ovarian Insufficiency' - List...
Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Women With Primary Ovarian Insufficiency (POI). * ... A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Insufficiency Patients. *Primary ...https://clinicaltrials.gov/ct2/results?term=Chromosome+Disorders&recrs=abc&cond=%22Primary+Ovarian+Insufficiency%22
Bone Marrow Stromal Cells That Enhanced Fibroblast Growth Factor-2 Secretion by Herpes Simplex Virus Vector Improve...
Nonmodified MSCs and FGF-2-modified MSCs were lifted as above just before transplantation and harvested. The harvested cells ... Identification of the Transplanted MSCs and Immunohistochemical Assessment for FGF-2. Before transplantation, the MSCs were ... MSCs were transferred the gene of interest before transplantation with virus vector ex vivo, and these gene-modified MSCs were ... MSC) transplantation improved neurological deficits after occlusive cerebrovascular disease. MSCs can differentiate into some ...http://stroke.ahajournals.org/content/36/12/2725
Umbilical Cord Mesenchymal Stem Cells Transplantation to Patients With Spinal Cord Injury - Tabular View - ClinicalTrials.gov
Experimental: UC-MSC Transplantation Intrathecal administration of up to 1x10^6 umbilical cord mesenchymal stem cells per kg to ... have scientific evidence as to the relative safety and efficacy of UC-MSCs transplantation for the treatment of spinal cord ... Umbilical Cord Mesenchymal Stem Cells Transplantation to Patients With Spinal Cord Injury. The safety and scientific validity ... A monocenter prospective cohort study will be performed to evaluate the effectiveness of UC-MSCs, for the treatment of ...https://clinicaltrials.gov/ct2/show/record/NCT02481440?recrs=abc&cond=%22Spinal+Cord+Injuries%22&rank=17
Safety and Efficacy of Human Umbilical Cord Derived Mesenchymal Stem Cells for Treatment of HBV-related Liver Cirrhosis - Full...
Other: UC-MSC transplantation After enrolled, Participant will receive umbilical cord MSC transplantation of 1*10E6 cells/kg ... MSCs hold great hope for therapeutic applications. Human umbilical cord-derived MSCs (hUC-MSCs) exhibit a more beneficial ... Experimental: UC-MSC transplantation Participants will receive umbilical cord derived mesenchymal stem cell treatment at day 1 ... Like MSCs derived from bone marrow, hUC-MSCs can also be used to treat rat liver fibrosis and improve glucose homeostasis in ...https://clinicaltrials.gov/ct2/show/NCT01728727?cond=%22North+American+Indian+childhood+cirrhosis%22+OR+%22Liver+Cirrhosis%22&rank=16
Cell Press Reviews: Stem Cells to Model and Treat Disease - 1st Edition
MSC Transplantation in Experimental Stroke Models. Clinical Studies on Intravenously Delivered Human MSCs ... Lessons from the Historical Development of HSC Transplantation. Stem Cell Therapeutics: Frontline Clinical Trials and Medical ... Lux IV Professor of Hematology/Oncology at Harvard Medical School and Director for the Stem Cell Transplantation Program at ... Bone Marrow-Derived Mesenchymal Stem Cells (MSCs). ...https://www.elsevier.com/books/cell-press-reviews-stem-cells-to-model-and-treat-disease/unknown/978-0-12-420191-0?utm_source=publicity&utm_medium=ElsConn&utm_campaign=CellPrRev
Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and...
Participants will be given hUC-MSCs transplantation.. Outcome Measures. Go to Study Description Study Design Arms and ... In this study, the safety and efficacy of Human Umbilical Cord Mesenchymal Stem Cells transplantation will be evaluated in ... Experimental: Human umbilical cord mesenchymal stem cells transplantation Intervention group. Biological: human umbilical cord ...https://clinicaltrials.gov/ct2/show/NCT01364246?cond=%22Devic+disease%22&rank=8
Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Hereditary Ataxia - Full Text View -...
Participants will be given hUC-MSCs transplantation.. Other Name: Intervention Group. Outcome Measures ... In this study, the safety and efficacy of Human Umbilical Cord Mesenchymal Stem Cells transplantation will be evaluated in ... This Study is designed to evaluate the the safety and efficacy of Human Umbilical Cord Mesenchymal Stem Cells transplantation ... Participants will be given umbilical cord mesenchymal stem cells transplantation with a 1 year follow-up. ...https://clinicaltrials.gov/ct2/show/NCT01360164?type=Intr&cond=mesenchymal&rank=62
Allogeneic Mesenchymal Stem Cells Transplantation for Primary Sjögren's Syndrome (pSS) - Full Text View - ClinicalTrials...
To assess adverse events of allogeneic MSC transplantation. *To assess the association of disease activity index, pSS serology ... Allogeneic Mesenchymal Stem Cells Transplantation for Primary Sjögren's Syndrome (pSS). The safety and scientific validity of ... Zhou K, Zhang H, Jin O, Feng X, Yao G, Hou Y, Sun L. Transplantation of human bone marrow mesenchymal stem cell ameliorates the ... Sun L, Akiyama K, Zhang H, Yamaza T, Hou Y, Zhao S, Xu T, Le A, Shi S. Mesenchymal stem cell transplantation reverses ...https://clinicaltrials.gov/ct2/show/NCT00953485
Improved Graft Mesenchymal Stem Cell Survival in Ischemic Heart With a Hypoxia-Regulated Heme Oxygenase-1 Vector | JACC:...
LV remodeling and cardiac function after MSCs transplantation. At day 14 after cell transplantation, the thickness of infarct ... transfected-male MSCs (MSCHO-1) and LacZ-transfected male MSCs (MSCLacZgroup) in 50 μl of volume were injected into syngenic ... were significantly better in the MSCHO-1group compared with MSCLacZ, MSCs, and medium group, indicating that survival MSCHO-1 ... MSCHO-1, n = 6) and MSCs group (5.54 ± 0.43 TUNEL+, p , 0.01 vs. MSCHO-1, n = 6) (Figs. 2A and 2B). This finding is inversely ...http://www.onlinejacc.org/content/46/7/1339
Abstract 2091: Clinical Trial of Autologous Bone Marrow Mesenchymal Stem Cell Transplantation for Severe Chronic Heart Failure ...
MSC transplantation significantly increased LV ejection fraction (23.9 ± 2.8% to 27.8 ± 2.7%, P , 0.05). MSC also increased ... Plasma BNP level significantly decreased after MSC transplantation.. Conclusions. This preliminary study suggests the safety ... Background. Experimental studies have shown that transplantation of mesenchymal stem cells (MSCs) improves cardiac function in ... The cultured MSCs secreted large amounts of angiogenic, antiapoptotic and mitogenic factors such as vascular endothelial growth ...http://circ.ahajournals.org/content/116/Suppl_16/II_453.2
Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice | Journal of Neuroinflammation |...
After transplantation, MMP-9 was decreased in protein and activity levels as compared with controls (p < 0.05). Furthermore, ... 105 mesenchymal stem cell transplantation. Neurobehavioral outcome, infarct volume, and blood-brain barrier permeability were ... MSC transplantation and labeling. For cellular tracking after transplantation, cells were labeled with carboxyfluorescein ... MSC isolation and identification. Bone-derived MSCs (MSCs) were isolated and harvested from adult male Sprague Dawley rats (SD ...https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-018-1153-1
Clinical Trials: Trauma | Stem Cells Portal - Stem Cells Journal Online Community
MSCs Transplantation; Biological: Injectable Collagen Scaffold with MSCs Transplantation. Sponsors: Chinese Academy of Sciences ... Injectable Collagen Scaffold™ Combined With MSCs Transplantation for Brain Injury Condition: Brain Injury. Interventions: ...http://stemcellsportal.com/clinical_trials_trauma?page=6