*  The Wnt-β-catenin pathway represses let-7 microRNA expression through transactivation of Lin28 to augment breast cancer stem...
Aberrant activation of the Wnt-β-catenin pathway has been found in a wide range of cancers, especially in cancers derived from ... Post-transcriptional repression of let-7 family miRNAs by Wnt-β-catenin pathway. Studies have shown that miRNAs play pivotal ... Activation of Lin28 is necessary for the Wnt-β-catenin pathway-induced let-7 repression and cell proliferation. To examine ... Activation of Lin28 is necessary for Wnt-β-catenin pathway-induced Let-7 repression and cell proliferation. (A) Knockdown of ...
  http://jcs.biologists.org/content/126/13/2877
*  MDM4 antibody | acris-antibodies.com
... and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. It inhibits degradation of ... MDM4 inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. It ...
  https://www.acris-antibodies.com/target/mdm4-antibody.htm
*  Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes |...
... a potential transcriptional adaptor required for function of certain acidic activation domains. Cell 70: 251-265. ... Henry KW, Wyce A, Lo WS, Duggan LJ, Emre NC, Kao CF, Pillus L, Shilatifard A, Osley MA, Berger SL (2003) Transcriptional ... Balasubramanian R, Pray‐Grant MG, Selleck W, Grant PA, Tan S (2002) Role of the Ada2 and Ada3 transcriptional coactivators in ... Kohler A, Zimmerman E, Schneider M, Hurt E, Zheng N (2010) Structural basis for assembly and activation of the heterotetrameric ...
  http://msb.embopress.org/content/7/1/503
*  JCI - Welcome
Most important, these transcriptional changes were accompanied by a marked decrease in whole-body energy expenditure. Short- ... Thus, the activation of the HBP by nutrients represents a biochemical link between nutrient availability, mitochondrial ... Recent studies have implicated fatty acid-dependent activation of the serine kinase IKKβ, which plays a key role in tissue ... Using high-density DNA microarrays and Northern analyses, we demonstrated that the activation of a nutrient-sensing pathway, ...
  https://www.jci.org/tags/20?content=articles&page=17
*  The Multi-Level Action of Fatty Acids on Adiponectin Production by Fat Cells
Liu M, Liu F. Transcriptional and post-translational regulation of adiponectin. Biochem J. 2010;425:41-52. [PubMed] ... These compounds induce multiple cellular responses, such as activation of protein kinases C and IκB, stimulation of ROS ... 8A). Apparently, these effects take place at a post-transcriptional level, as knock down of sortilin does not change the level ... Translocation of small preformed vesicles is responsible for the insulin activation of glucose transport in adipose cells. ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3226650/?lang=en-ca
*  Bcl3抗体[Ham150-3.5]|Abcam中国|Anti-Bcl3抗体[Ham150-3.5]
Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear ... In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the ...
  http://www.abcam.cn/bcl3-antibody-ham150-35-ab15046.html
*  Dietary Restriction Promotes Vessel Maturation in a Mouse Astrocytoma
"Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene," Cancer Cell, vol. 3, no. 4, pp. 347- ... VEGF activation of VEGF-R2 suppresses PDGF-Rβ signaling in VSMCs through the assembly of a complex consisting of the two ...
  https://www.hindawi.com/journals/jo/2012/264039/
*  Protocols and Video Articles Authored by Rohini Kuner (Translated to Italian)
Activation of plexin-B1 by semaphorin 4D regulates PDZ-RhoGEF/LARG activity leading to RhoA activation. In addition, a dominant ... Transcriptional Mechanisms Underlying Sensitization of Peripheral Sensory Neurons by Granulocyte-/granulocyte-macrophage Colony ... An activation of Plexin-B1 via its ligand, semaphorin 4D (Sema4D), produces an acute collapse of axonal growth cones in ... The activation of receptor tyrosine kinases and the Rho kinase following Sema4D treatment was found to control dendritic and ...
  https://www.jove.com/author/Rohini_Kuner?language=Italian
*  Difference between revisions of "Erman's Lab" - OpenWetWare
We are trying to identify transcriptional enhancers of the IL7-R gene locus using bioinformatics and gene reporter assays. We ... and NF-kappaB activation. In such cells we introduce plant cDNA's and identify novel factors that modulate TCR signal ... Signaling by the TCR activates various transcription factors that translocate to the nucleus to bind to transcriptional control ... Whether TCR stoichiometry is static during different developmental stages and during activation is not known. We are performing ...
  https://openwetware.org/wiki/?title=Erman
*  PUBLICATIONS - Curriculum vitae laurie k. Mccauley
Koh AJ, Beecher CA, Rosol TJ, McCauley LK. Cyclic AMP activation in osteoblastic cells: Effects on PTH-1 receptors and ... Yamashita J, McCauley LK. The activating protein-1 transcriptional complex: Essential and multifaceted roles in bone. Clinical ...
  http://dentisty.org/curriculum-vitae-laurie-k-mccauley.html?page=5
*  GSC Gene - GeneCards | GSC Protein | GSC Antibody
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding. IEA. --. ... GSC CRISPR Activation Plasmid (h2). * GenScript: Design CRISPR guide RNA sequences for GSC ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=GSC&phen=17&rf=/home/genecards/current/website/carddisp.pl
*  Plus it
... presumably reflecting differences in transcriptional or posttranscriptional events in neuronal perikarya (Noebels et al., 1991 ... Salicylate Induces Tinnitus through Activation of Cochlear NMDA Receptors *. Visuomotor Behaviors in Larval Zebrafish after GFP ...
  http://www.jneurosci.org/content/21/7/2288
*  JCI - Volume 127, Issue 5
These results reveal a cooperative transcriptional activation mechanism of AEP and DOT1L and suggest a molecular rationale for ... activate transcription by aberrantly inducing both AEP-dependent transcriptional activation and DOT1L-dependent transcriptional ... conferring different transcriptional properties including activation, maintenance, and repression. The mixed-lineage leukemia ( ... We also identified inhibitor of DNA binding protein 2 (ID2) as a key upstream regulator of KDR activation during myeloid ...
  https://hzyouma.com.www.mobile.jci.org/127/5
*  Гостьова книга - Баришівський навчально-виховний комплекс 'гімназія-загальноосвітня школа І-ІІІ ступенів'
The pervasive generation of indi- vidual mRNAs away post-transcriptional processing from polycistronic transcripts implies that ... Aside from direct neuronal activation, proinflammatory cytokines alter synaptic transference in dorsal horn neurons. Papers (c ... gene decree is exerted by post-transcriptional mechanisms such as modulation of mRNA reliability and sending (Kramer 2012). In ...
  http://nvk.in.ua/%D0%B3%D0%BE%D1%81%D1%82%D1%8C%D0%BE%D0%B2%D0%B0-%D0%BA%D0%BD%D0%B8%D0%B3%D0%B0/?from=610&select=62
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... with the transcriptional coactivator PGC1-α as an important intermediate 9,10. Despite the importance of exercise as a tool for ... and RyR contributes to Ca2+ spark activation in skeletal muscle. In summary, our studies using osmotic stress induced Ca2+ ... Computational simulations of ventricular activation maps and pseudo-ECGs in sinus rhythm and ventricular tachycardia indicated ...
  https://www.jove.com/visualize/abstract/25121500/the-relationship-between-muscle-fiber-type-specific-pgc-1-content
*  Difference between revisions of "User:Etienne Robillard/Notebook/Agent BZ" - OpenWetWare
... implicated in gene transcriptional activation. ([http://en.wikipedia.org/wiki/Autoinducer#Vibrio_fischeri:_bioluminescence 1]) ... it requires co-activation by two ligands: glutamate and '''[http://en.wikipedia.org/wiki/Glycine glycine]'''.[7]'. ...
  https://openwetware.org/wiki/?title=User:Etienne_Robillard/Notebook/Agent_Ecoli:PhotoReceptorComponent&diff=cur&oldid=633745
*  Non-selective CCK | Role of NK1 and NK2 receptors in mouse gastric mechanical activity
Results: Both E208K and V324M augment channel response to MgADP activation without altering level of sensitivity to ATP4? or ... Background The investigation of molecular mechanisms underlying transcriptional regulation, particularly in * The hexahistidine ... Channel activation by Mg-nucleotides entails nucleotide binding/hydrolysis at NBFs which induces a conformational switch in ... The results demonstrate that E208K and V324M located in unique domains of SUR1 enhance transduction of Mg-nucleotide activation ...
  http://stopvivisection.info/category/non-selective-cck/
*  Protocols and Video Articles Authored by Baltasar Lucendo-Villarin (Translated to Korean)
LPO exposure induced an NAFLD phenotype in HLCs with transcriptional and metabolomic dysregulation consistent with those ... Interestingly, cell depletion was less pronounced in female hepatocytes, whereas caspase activation was ~twofold greater, ... HLCs treated with LPO recapitulate the transcriptional and metabolic dysregulation seen in NAFLD and additionally retain ...
  https://www.jove.com/author/Baltasar_Lucendo-Villarin?language=Korean
*  A Proteomics Approach to Study Soybean and Its Symbiont Bradyrhizobium japonicum -A Review | IntechOpen
Some recent literature has also shown that jasmonates can also cause nod gene activation in B. japonicum although the strain ... At the transcriptional level, the expression of genes for alcohol fermentation, ethylene biosynthesis, pathogen defense, and ... Transcriptional and translational level changes were observed for hemoglobin, acid phosphatase, and Kunitz trypsin protease ... Glucose degradation and sucrose accumulation increased due to activation of glycolysis and down-regulation of sucrose degrading ...
  https://www.intechopen.com/books/a-comprehensive-survey-of-international-soybean-research-genetics-physiology-agronomy-and-nitrogen-relationships/a-proteomics-approach-to-study-soybean-and-its-symbiont-bradyrhizobium-japonicum-a-review/
*  TBC1D28 Gene - GeneCards | TBC28 Protein | TBC28 Antibody
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative ... Vectors and viruses for KO, Activation, Repression, and more. *TBC1D28-CRISPR-CAS9-Knockout ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=TBC1D28
*  MDAR5 - Monodehydroascorbate reductase, chloroplastic/mitochondrial precursor - Arabidopsis thaliana (Mouse-ear cress) - MDAR5...
"Empirical analysis of transcriptional activity in the Arabidopsis genome.". Yamada K., Lim J., Dale J.M., Chen H., Shinn P., ... by activation or inhibition) the reaction.,p>,a href='/help/enzyme_regulation' target='_top'>More...,/a>,/p>Enzyme regulationi ...
  http://www.uniprot.org/uniprot/P92947
*  Rama Natarajan, Ph.D., at City of Hope | Los Angeles | Southern California
Kato M, Wang L, Putta S, Wang M, Yuan H, Sun G, Lanting L, Todorov I, Rossi JJ, and Natarajan R. (2010). Post-transcriptional ... Jin F, Li Y, Ren B, Natarajan R. (2011) PU.1 and C/EBPa synergistically program distinct response to NF-κB activation through ... 2013) FOG2 down-regulation by TGF-β-induced microRNA-200b/c leads to Akt kinase activation and Glomerular Mesangial Hypertrophy ... and monocyte activation due to altered expression of inflammatory cytokines, chemokines and lipids under diabetic conditions. ...
  https://www.cityofhope.org/espanol/faculty/rama-natarajan
*  Shp1 | Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors
a 50-65 kDa Fcg receptor IIIa FcgRIII) AG-490 AMN-107 as well as in signal transduction and NK cell activation. The CD16 blocks ... Nevertheless the transcriptional regulation of murine genes is understood currently badly. Fifteen murine genes have already ...
  http://researchreport-digital.com/category/shp1/
*  Phospho-SXXE/D Motif Mediated TNF Receptor 1-TRADD Death Domain Complex Formation for T Cell Activation and Migration | The...
In 293T cells, transient transfection of either TNFR1 or TRADD alone could trigger NF-κB transcriptional activation, as ... Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation. ... NF-κB activation has tissue-specific effects on immune cell apoptosis during polymicrobial sepsis. Shock 18: 380-386. ... TNF can also induce NF-κB activation or other cellular responses in a variety of cell types. We show in this study that TNF- ...
  http://www.jimmunol.org/content/187/3/1289.long