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*  Biomedicines | Free Full-Text | Decoding the Pluripotency Network: The Emergence of New Transcription Factors | HTML
Among the various regulations that orchestrate the cellular pluripotency program, transcriptional regulation is situated in the ... Their N-terminal region is the highly variable A/B domain that contains at least one transcriptional activation function 1 ... Transcriptional interaction with core factors. Reference. Esrrb. Interacts with Oct4, Nanog, Sox2 and Ncoa3;. [41,44,45,46,47, ... Maintains X-activation, imprinting, cell cycle, and mitochondrial fission in ESCs.. Zscan4. Overexpression or knockdown Zscan4 ...
  http://www.mdpi.com/2227-9059/1/1/49/htm
*  Histone-binding protein RBBP7
Activation of HOX genes during differentiation 86 Activation of anterior HOX genes in hindbrain development during early ... which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, ... which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone ...
  https://pharos.nih.gov/idg/targets/Q16576
*  In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila | Genetics
In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Shuailiang Lin, Ben Ewen-Campen, Xiaochun Ni, Benjamin E. ... In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Shuailiang Lin, Ben Ewen-Campen, Xiaochun Ni, Benjamin E. ... In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Shuailiang Lin, Ben Ewen-Campen, Xiaochun Ni, Benjamin E. ... providing the first demonstration of dCas9 activation in a multicellular animal. Transcriptional activation using dCas9-VPR ...
  http://www.genetics.org/content/201/2/433
*  The Oncogenic EWS-FLI1 Protein Binds In Vivo GGAA Microsatellite Sequences with Potential Transcriptional Activation Function
Moreover, in reporter gene experiments, the transcription activation is highly dependent upon the number of repeats that are ... Importantly, in vivo EWS-FLI1-bound microsatellites are significantly associated with EWS-FLI1-driven gene activation. Put ... 1994) DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) ... Transcriptional control Is the Subject Area "Transcriptional control" applicable to this article? Yes. No. ...
  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004932
*  In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate | Science
In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ... In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ... In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ... In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ...
  http://science.sciencemag.org/content/258/5085/1143
*  Tetracycline-controlled transcriptional activation - Wikipedia
Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly ... "Transcriptional activation by tetracyclines in mammalian cells". Science. 268 (5218): 1766-1769. doi:10.1126/science.7792603. ... It is also human codon optimized and composed of 3 minimal VP16 activation domains. However, the Tet-On 3G protein has 5 amino ... In the Cre and FRT systems, activation or knockout of the gene is irreversible once recombination is accomplished, whereas, in ...
  https://en.wikipedia.org/wiki/Tetracycline-controlled_transcriptional_activation
*  Kinetics vs. equilibrium binding: Determining the mechanism of transcriptional activation of Polymerase II
The mechanism of transcriptional activation of Polymerase II (Pol II) can be studied in a unique way by using a model ... equilibrium binding: Determining the mechanism of transcriptional activation of Polymerase II. James, Jennifer ... Activation of Pol II by L148F and L148H showed a 20 fold and 3 fold increase over the wild type. The question to be answered is ... If the in vivo concentration is much higher than the equilibrium binding constant, then the activation binding site should be ...
  https://mospace.umsystem.edu/xmlui/handle/10355/1713
*  Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells | Cancer Research
Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells. Wei Jin, William N ... Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells ... Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells ... Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells ...
  http://cancerres.aacrjournals.org/content/66/8_Supplement/141.1
*  "Mechanism of transcriptional activation by Pseudomonas aeruginosa ExsA" by Christopher Anthony Vakulskas
Finally, I characterized the mechanism of transcriptional activation by ExsA. ExsA-dependent promoters contain regions that ... In the work presented here I examine the stoichiometry, ligand-interaction properties, and transcriptional activation mechanism ... Transcriptional activators generally recruit RNAP by contacting the α or σ70 subunits (or both). I have found that ExsA ... ExsA is an AraC-family transcriptional regulator that controls expression of T3SS genes in P. aeruginosa. ExsA binds to DNA at ...
  https://ir.uiowa.edu/etd/612/
*  Test No. 455: The Stably Transfected Human Estrogen Receptor-alpha Transcriptional Activation Assay for Detection of Estrogenic...
455: The Stably Transfected Human Estrogen Receptor-alpha Transcriptional Activation Assay for Detection of Estrogenic Agonist- ... 455: The Stably Transfected Human Estrogen Receptor-alpha Transcriptional Activation Assay for Detection of Estrogenic Agonist- ...
  https://www.oecd-ilibrary.org/environment/test-no-455-the-stably-transfected-human-estrogen-receptor-alpha-transcriptional-activation-assay-for-detection-of-estrogenic-agonist-activity-of-chemicals_9789264076372-en
*  Progestins induce transcriptional activation of signal transducer and activator of transcription 3 ( | Hotze Health & Wellness...
Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (. By: Hotze Health , Tags ... These results demonstrate that progestins are able to induce Stat3 transcriptional activation, which is in turn an obligatory ... June 2005). Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a ...
  https://www.hotzehwc.com/2011/06/progestins-induce-transcriptional-activation-of-si/
*  High glucose increases transcriptional activation of VEGF in bovine retinal endothelial cells via peroxynitrite. | IOVS | ARVO...
D.H. Platt, M. Bartoli, T. Lemtalsi, R.B. Caldwell; High glucose increases transcriptional activation of VEGF in bovine retinal ... High glucose increases transcriptional activation of VEGF in bovine retinal endothelial cells via peroxynitrite. ... High glucose increases transcriptional activation of VEGF in bovine retinal endothelial cells via peroxynitrite. ... STAT3 activation was monitored by western analysis of tyrosine phosphorylation. Results: High glucose (25mM) stimulation of BRE ...
  http://iovs.arvojournals.org/article.aspx?articleid=2406305
*  Comparative Genome Analysis Identifies the Vitamin D Receptor Gene as a Direct Target of p53-Mediated Transcriptional...
Transcriptional activation of VDR target genes by p53, p63γ, or p73. HCT116 cells were infected with Ad-LacZ, Ad-p53, Ad-p63γ, ... The results suggest that VDR plays a key role in the transcriptional activation of a subset of p53 target genes ( Fig. 7B). We ... VDR enhances the transcriptional activation of TP53 downstream genes. We next examined whether the induction of expression of ... Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic ...
  http://cancerres.aacrjournals.org/content/66/9/4574
*  Glucocorticoids induce the expression of the leptin gene through a non-classical mechanism of transcriptional activation -...
... the induction of the expression of the leptin gene by dexamethasone is at least in part due to a transcriptional activation ... Glucocorticoids induce the expression of the leptin gene through a non-classical mechanism of transcriptional activation De Vos ... Home , Glucocorticoids induce the expression of the leptin gene through a non-classical mechanism of transcriptional activation ... the induction of the expression of the leptin gene by dexamethasone is at least in part due to a transcriptional activation ...
  https://infoscience.epfl.ch/record/135316
*  AID 70334 - In vitro inhibition of transcriptional activation induced by 1 nM 17-beta estradiol in T47D cells expressing...
In vitro inhibition of transcriptional activation induced by 1 nM 17-beta estradiol in T47D cells expressing estrogen receptor ...
  https://pubchem.ncbi.nlm.nih.gov/bioassay/70334
*  AID 156930 - Inhibition of transcriptional activation of human Peroxisome proliferator activated receptor gamma in CHO-K1 cells...
Inhibition of transcriptional activation of human Peroxisome proliferator activated receptor gamma in CHO-K1 cells;ia means ...
  https://pubchem.ncbi.nlm.nih.gov/bioassay/156930
*  Maximal transcriptional activation of piscine soluble Toll-like receptor 5 by the NF-κB subunit p65 and flagellin
... ... To better understand the transcriptional regulation of TLR5S gene in fish, we determined the TLR5S 5′-flanking sequence region ...
  https://insights.ovid.com/fshimu/201112000/00013844-201112000-00020
*  KAKEN - Research Projects | Transcriptional activation of the HTLV-I gene in monocytes and macrophages. (KAKENHI-PROJECT...
In the present study, we clarified cell-type sp … More ecific transcriptional activation of the HTLV-I LTR in monocytes. CAT ... Transcriptional activation of the HTLV-I gene in monocytes and macrophages.. Research Project ... We propose cell-type specific transcriptional regulation of the HTLV-I gene in monocytes and T-cells. Less ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13671089/
*  Dual phosphorylation in response regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon...
... regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon transcriptional activation. Alok K ... regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon transcriptional activation ... regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon transcriptional activation ... regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon transcriptional activation ...
  http://www.biochemj.org/content/474/24/4119.article-info
*  AID 82030 - Antagonistic effect on 1 nM estradiol induced transcriptional activation in HEC-1 cells expressing estrogen...
Antagonistic effect on 1 nM estradiol induced transcriptional activation in HEC-1 cells expressing estrogen receptor beta at ...
  https://pubchem.ncbi.nlm.nih.gov/bioassay/82030
*  Propofol post-conditioning alleviates hepatic ischaemia reperfusion injury via BRG1-mediated Nrf2/HO-1 transcriptional...
Propofol post-conditioning alleviates HIRI through BRG1-mediated Nrf2/HO-1 transcriptional activation. ... post-conditioning alleviates hepatic ischaemia reperfusion injury via BRG1-mediated Nrf2/HO-1 transcriptional activation in ...
  https://www.physiciansweekly.com/propofol-post-conditioning-alleviates-hepatic-ischaemia-reperfusion-injury-via-brg1-mediated-nrf2ho-1-transcriptional-activation-in-human-and-mice/
*  Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is...
Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is ... Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is ... Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is ... Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is ...
  http://www.biochemj.org/content/377/3/797
*  Association of Transcription Factor IIA with TATA Binding Protein Is Required for Transcriptional Activation of a Subset of...
Activation of the GAL1 gene by the VP16 activation domain was unaffected by the toa2 W76A mutation, while the HAP4 activation ... Lieberman P M, Berk A J. A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA- ... The activation domains of the herpesvirus VP16 and yeast HAP4 transcriptional activators were fused to the GAL4 DNA binding ... Stargell L, Struhl K. Mechanisms of transcriptional activation in vivo: two steps forward. Trends Genet. 1996;12:311-315. [ ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC110636/?lang=en-ca