Loading...
*  Does the prenatal bisphenol A exposure alter DNA methylation levels in the mouse hippocampus?: An analysis using a high...
Genes and Environment" on DeepDyve, the largest online rental service for scholarly research with thousands of academic ... However, they did not study whether there was any alteration in other genes. Control Using inbred BALB/c mice, there was a ... and closed colonies such as ICR mice and SD rats show genetic 50% in SD and Fisher 344 rats, respectively [41]. Further- ... methylated the transcriptional regulatory region of the hippocampal neurotrophic factor (BDNF) of the males and consequently ...
  https://www.deepdyve.com/lp/springer_journal/does-the-prenatal-bisphenol-a-exposure-alter-dna-methylation-levels-in-HMizYIy4Bp
*  Protocols and Video Articles Authored by Atsuo Ogura (Translated to Portuguese)
Apr, 2005 , Pubmed ID: 15897628 ICR-derived glomerulonephritis (ICGN) mice are a novel inbred strain with hereditary nephrotic ... congenic breeding is essential for analyzing the genes of interest on specific genetic backgrounds and for analyzing ... These mice will be useful for the study on the development of iNKT cells as well as on their functions in the immune system. ... These embryos were analyzed for the events associated with transcriptional regulation. Changes in transcriptional activity, ...
  https://www.jove.com/author/Atsuo_Ogura?language=Portuguese
*  Protocols and Video Articles Authored by Atsuo Ogura (Translated to German)
Apr, 2005 , Pubmed ID: 15897628 ICR-derived glomerulonephritis (ICGN) mice are a novel inbred strain with hereditary nephrotic ... In the present study, because lower levels of MMP activity may contribute to the progression of renal fibrosis in ICGN mice, ... TPAP-deficient mice display impaired expression of haploid-specific genes that are required for the morphogenesis of germ cells ... To date, cells, such as mature lymphocytes, with genetic differentiation markers have been cloned to generate mice only via a ...
  https://www.jove.com/author/Atsuo_Ogura?language=German
*  Transcriptome profiling of liver of non-genetic low birth weight and long term health consequences | BMC Genomics | Full Text
All study groups consisted of mice from at least 14 different litters. ICR (CD-1®) Outbred Mice (Harlan) were used to quantify ... Indeed, in M males, only a few post-transcriptional modifications and enrichment in metabolic genes and the corresponding ... In the current study, we examined natural birth weight variations in inbred mice (homozygous at every allele) to determine how ... Red arrows: upregulated genes; Green arrows: downregulated genes; (A) Venn diagram of MM vs MF and CM vs CF mice (B) Venn ...
  https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-15-327
*  Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation | Development
... is dependent on genetic background, with B6D2F1 and DBA2 mice expressing the mutant phenotype, whereas C57BL/6J and FVB mice do ... under the chicken β-actin/CMV immediate early enhancer promoter in an inbred C57BL/6J background [strain B6.129(ICR)-Tg(ACTB- ... which leads to the induction of target genes by transcriptional activator forms of Gli transcription factors (GLI1, GLI2 or ... The derivative strain B6C3Fe-a/a-Ptch1mes/J (stock number 001430) was obtained for this study. Homozygous Ptch1mes mice of both ...
  http://dev.biologists.org/content/136/9/1423
*  4 Information Related to Biologic Plausibility | Veterans and Agent Orange: Update 2008 | The National Academies Press
Mice, C5BL/6J 24.4 daysc Mice, DBA/2J 12.6 daysc Mice, B6D2F1/J Koshakji et al., 1984 20 days Mice, male ICR/Ha Swiss Hurst et ... and genetic differences between people, all of which can be controlled in a laboratory animal study. Once a chemical contacts ... and other genes involved in extracellular matrix deposition in cells from mice with homozygous ablation of the Ahr gene (Guo et ... Analysis of the transcriptional regulation and molecular function of the aryl hydrocarbon receptor repressor in human cell ...
  https://www.nap.edu/read/12662/chapter/6
*  Protocols and Video Articles Authored by Atsushi Yoshiki (Translated to Hindi)
Inbred mouse strains have provided uniform genetic background for accurate evaluation of specific genes phenotypes, thus ... In this study, we demonstrate that Re and M100573 mice bear mutations in the type I IRS gene Krt25; Re(wc) mice bear an ... We also injected Mol/MSM-1 ES cells into blastocysts of ICR or C57BL/6 x BDF1 mice and found that blastocyst injection resulted ... Furthermore, only the domain-C transcriptional level did not show an obvious change in progress following HSV injection. These ...
  https://www.jove.com/author/Atsushi_Yoshiki?language=Hindi
*  Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and...
The entire series of mutant Rosa26 sentinel alleles was established on an inbred C57BL/6J background. All mice were maintained ... 1992). Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo. Development 116, 357- ... In the present study, we circumvented these problems by devising a system to conveniently insert multimerized signaling ... We show that the system efficiently allows the production of an allelic series of genetic sentinels to monitor diverse types of ...
  http://dmm.biologists.org/content/5/6/956
*  Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome | Development
However, in mice with uniform genetic backgrounds (inbred mice and F1 mice), we have observed variable expressivity. We have ... Both of the mouse genes and their human counterparts can act as transcriptional repressors (Carlson et al., 2001; Carreira et ... and 129 inbred. Analysis of embryos was performed on these backgrounds, as well as on random-bred Swiss-Webster and ICR mice ( ... although the status of each individual placode was not reported in this study. The deficiency of mammary placodes in mice ...
  http://dev.biologists.org/content/130/10/2263
*  HSF1 is required for extra‐embryonic development, postnatal growth and protection during inflammatory responses in mice | The...
... inbred BALB/c and outbred ICR wild‐type females, respectively. Accordingly, these targeted mutant strains are referred to ... Genetic studies in mice have implicated several factors in determining the cell fate and differentiation of major trophoblast ... Scharf KD, Rose S, Zott W, Schoffl F, Nover L and Schoff F (1990) Three tomato genes code for heat stress transcription factors ... Cahill CM, Waterman WR, Xie Y, Auron PE and Calderwood SK (1996) Transcriptional repression of the prointerleukin 1β gene by ...
  http://emboj.embopress.org/content/18/21/5943
*  Frontiers | Screening for stress-resistance mutations in the mouse | Genetics
... to rapidly identify the causative genes, and to develop mice for in vivo studies. ... to rapidly identify the causative genes, and to develop mice for in vivo studies. ... are capable of generating live mice, and (4) transmit the stress resistance phenotype to the mice. This strategy offers an ... are capable of generating live mice, and (4) transmit the stress resistance phenotype to the mice. This strategy offers an ...
  https://www.frontiersin.org/articles/10.3389/fgene.2014.00310/full
*  UW Genome Sciences: past GS Seminars
"Population genetics of wild and inbred house mice: insights into speciation and the use of mice as models for biomedical ... The transcriptional activity of human Chromosome 22. Genes Dev. 17:529-540. ... Space, Time and Genetic Networks' Jointly sponsored with COMBIWed., May 29. GENOME SCIENCES SYMPOSIUM: 'Genetic Variation in ... NHLBI/Framingham Heart Study. "Evolving Genomic Approaches to the Study of Complex Cardiovascular Diseases in Human Populations ...
  http://www.gs.washington.edu/news/pastseminars.htm
*  Calm1 signaling pathway is essential for the migration of mouse precerebellar neurons | Development
For all experiments, we used inbred ICR mouse strains obtained from Japan SLC (Hamamatsu, Japan). Noon of the day of vaginal ... In our study, mRNAs of all three CaM genes were localized in the proximal region of the leading process. However, the ... In mice, the peak of LRN/ECN neuron generation is around E12, that of PN neurons is around E12-14, and that of ION neurons is ... Hierarchical genetic interactions between FOXG1 and LHX2 regulate the formation of the cortical hem in the developing ...
  http://dev.biologists.org/content/142/2/375
*  Strictly co-isogenic C57BL/6J-Prnp−/− mice: A rigorous resource for prion science | JEM
Our study demonstrate that this approach may also be applicable to genes for which knockout mice are already available (and ... Prnp-ablated allele on a pure C57BL/6J genetic background. Genomic, transcriptional, and phenotypic characterization of PrnpZH3 ... ICR) mice purchased from The Jackson Laboratory, Charles River, or bred in-house. Genetically vasectomized mice (Haueter et al ... Copy number variants (CNVs) are frequently observed among different individuals of the same inbred colony of laboratory mice, ...
  http://jem.rupress.org/content/early/2016/02/23/jem.20151610
*  The Evolutionary Fates of a Large Segmental Duplication in Mouse | Genetics
Mice. Wild M. musculus mice used in this study were trapped at a large number of sites across Europe, the United States, the ... 4 classical inbred strains (ALS/LtJ, ALR/LtJ, CHMU/LeJ and NU/J), 1 line derived from the ICR:HsD outbred stock (HR8; Swallow ... T. Pavelitz, J. R. Kidd, K. K. Kidd, and A. M. Weiner, 1997 Concerted evolution of the tandemly repeated genes encoding human ... We obtained expected recombination fractions from the standard mouse genetic map (Cox et al. 2009), which was constructed from ...
  http://www.genetics.org/content/204/1/267
*  Department of Biology
and genetic selection on muscle metabolic capacities in house mice Mus domesticus. Journal of Applied Physiology 89:1608-1616. ... Mouse inbred strain differences in ethanol drinking to intoxication.. Genes, Brain and Behavior 6:1-18. [PDF File]. 143. ... in mice: transcriptional analysis and mapping of expression QTL in muscle. Physiological Genomics 46:593-601. [PDF file]. 254. ... Clostridial enteropathy in lactating outbred swiss-derived (ICR) mice. Journal of the American Association for Laboratory ...
  https://biology.ucr.edu/people/faculty/Garland/GarlandPublications.html
*  3-methylcholanthrene: Topics by WorldWideScience.org
In the present study, seven-week-old male ICR mice received intraperitoneal injections of 0, 0.01, 0.1 or 1mg/kg body weight 3- ... However, a genetic polymorphism was identified at nt 708 in intron 4 of the DBA/2 strain of mice 5 bp downstream of a 3' ... Results During promotion, the majority of genes identified in the BALBLps-d compared to BALB/c mice (P Ereg, secreted ... functions as an in vivo lung tumor promoter among different inbred strains of mice. Further, we identified a positive ...
  https://worldwidescience.org/topicpages/0-9/3-methylcholanthrene.html
*  Peter's Blog: December 2008
Van der Loos H, Dörfl J, Welker E (1984) Variation in pattern of mystacial vibrissae in mice. A quantitative study of ICR stock ... Human-specific transcriptional regulation of CNS development genes by FOXP2. Nature 462:213-217. ... Genetic knock-out mice lacking glutamate receptors may not develop barrels and their equivalents in thalamus and brainstem, ... and several inbred strains.. J Hered 75: 326-336.. *Van der Loos H, Woolsey TA (1973) Somatosensory cortex: structural ...
  http://brainmindinst.blogspot.com/2008/12/
*  Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis | Genome Medicine | Full Text
Such effects, however, could lead to conflicts among studies, while further impacting study outcomes and efforts to translate ... The response of MOLF males was aberrant, however, with decreased expression of differentiation-associated genes (elevated in ... These findings demonstrate strain-dependent aspects of IMQ dermatitis in mice. We have shown that IMQ does not uniquely model ... Although IMQ-induced expression shifts mirrored psoriasis, responses in BALB/c, 129/SvJ, DBA, and MOLF mice were more ...
  https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-017-0415-3
*  Metagenomic cross-talk: the regulatory interplay between immunogenomics and the microbiome | Genome Medicine | Full Text
Understanding the reciprocal genetic and epigenetic control between host and microbiota will be an important step towards the ... encompasses up to 100-fold more genes than the host genome. In contrast to the human genome, the microbial genome is flexible ... A genetic linkage study examined a cross between the C57BL/6 J inbred mouse strain and an ICR/HaJ-derived outbred line to ... Indeed, upon microbial colonization of germ-free mice, major transcriptional induction of innate and adaptive immune genes ...
  https://0-genomemedicine-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s13073-015-0249-9
*  Protocols and Video Articles Authored by Thomas E. Johnson (Translated to Portuguese)
The current study examines the genetic components of LDA in the ILS and ISS mice that are inbred derivatives of LS and SS and ... This study demonstrated that a 2-wk interval between cage changes for ICR female mice housed in IVC caging (with approximately ... The genetic variation also implies the existence of genes that would be novel therapeutic targets, distinct from genes ... A transcriptional upregulation was confirmed in the current study by analyzing Ce-GST-p24 promoter-reporter constructs in ...
  https://www.jove.com/author/Thomas+E._Johnson?language=Portuguese
*  Joseph Garner | Stanford Medicine Profiles
Albino and pigmented inbred mice of the strain C57BL/6NCrl (B6) and outbred mice of the stock Crl:CF1 (CF1) were used to ... Our interests lie in determining the genes and genetic pathways that are important for establishing and maintaining maternal- ... Cage-induced stereotypies in female ICR CD-1 mice do not correlate with recurrent perseveration BEHAVIOURAL BRAIN RESEARCH ... was calculated based on a total population of 70 postpartum female mice on study. This finding was preceded by 3 typical ...
  https://med.stanford.edu/profiles/joseph-garner
*  David A. Stevens | Stanford Medicine Profiles
... genes involved in virulence, and susceptibility to infection with Aspergillus. Mice with genetic immunological deficiency and ... The immunological basis for a >10-fold resistance of outbred CD-1 mice compared to inbred BALB/c mice to pulmonary ... In the initial study, groups of mice were given saline, or 1, 3 or 10 mg kg(-1) of MICA b.i.d., s.c. All saline controls, and ... Interaction between conidia, lung macrophages, immunosuppressants, proinflammatory cytokines and transcriptional regulation ...
  https://med.stanford.edu/profiles/david-stevens
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Behavior, Issue 89, mice, inbred C57BL, social behavior, animal models, autism, BTBR, motor stereotypy, repetitive ... The transcriptional activity of RNA polymerase II (Pol II) is a dynamic process and therefore measuring the kinetics of the ... It is especially promising as a first-step tool to study the effects of drugs or mutations on basic behavioral patterns. The ... for assessing the effects of genetic and pharmacological manipulations on basic mechanisms of cognition and learning in mice. A ...
  https://www.jove.com/visualize/abstract/25369269/modeling-warfare-in-social-animals-a-chemical-approach
*  NON-HUMAN MAMMALS WITH T OR B CELLS HAVING PREDEFINED SPECIFICITY - Patent application
... technique can be applied using inbred or outbred mice as donors. The recipient oocytes were obtained from Black6×DBA2 F2 mice ... without genetic modification. In certain embodiments of the invention the TCR and BCR genes retain their endogenous regulatory ... A transcriptional reporter could comprise a nucleic acid encoding a marker protein wherein the nucleic acid is operably linked ... Mouse strains of interest include, e.g., Balb/c, Black6, C57BL/6, DBA/1, DBA/2, ICR, NOD, 129 strains such as 129/Sv, etc., and ...
  http://www.patentsencyclopedia.com/app/20110302665