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*  British Library EThOS: A comparison of host-parasite interactions between Toxoplasma gondii and Neospora caninum
A comparison of host-parasite interactions between Toxoplasma gondii and Neospora caninum ... To fully understand these biological differences, the host-parasite interactions of these parasites have been investigated in ... TgGRA2 was successfully purified by HPLC and attempts have been made to study its role in host-parasite interactions using a ... Due to the importance of protein-protein interactions (PPIs) and multiple protein complexes (MPCs) in host-parasite ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677498
*  Cells | Free Full-Text | How Can Elispot Add Information to Improve Knowledge on Tropical Diseases?
... for accessing the profile of immune response as well as the recent advances in information about host-pathogen interaction in ... products and functions and has facilitated the understanding of host-pathogen interaction. Despite the incredible diversity of ... Use of Human Neurons Derived via Cellular Reprogramming Methods to Study Host-Parasite Interactions of Toxoplasma gondii in ... products and functions and has facilitated the understanding of host-pathogen interaction. Despite the incredible diversity of ...
  https://www.mdpi.com/2073-4409/6/4/31
*  Rhoptry - Wikipedia
"Proteomic Analysis of Rhoptry Organelles Reveals Many Novel Constituents for Host-Parasite Interactions in Toxoplasma gondii". ... The proteins they contain are important in the interaction between the host and the parasite. Rigoulet, Jacques; Hennache, ... Parasite. 21: 62. doi:10.1051/parasite/2014062. ISSN 1776-1042. PMC 4236686 . PMID 25407506. Bradley, Peter J; Chris Ward; ... They are club-shaped organelles connected by thin necks to the extreme apical pole of the parasite. These organelles, like ...
  https://en.wikipedia.org/wiki/Rhoptry
*  ApiLoc
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii.. ... These obligate intracellular parasites comprise some of the most important parasites of humans and animals, including the ... and proteases that are likely to play a key role in the ability of the parasite to invade and co-opt the host cell for its own ... Species: Toxoplasma gondii. *Quote inferring localisation: "Staining for ROP15 appears to extend into the rhoptry necks at the ...
  http://apiloc.biochem.unimelb.edu.au/apiloc/apiloc/publication/16002398
*  The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation |...
... to analyze the proteome of Toxoplasma gondii, a parasite of medical and veterinary significance, and have developed a public ... The draft genome for Toxoplasma predicts around 8,000 genes with varying degrees of confidence. Our data demonstrate how ... Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J ... Protein databases: a Toxoplasma database was assembled (see above). To identify contaminant host proteins, the parasite ...
  https://genomebiology.biomedcentral.com/articles/10.1186/gb-2008-9-7-r116
*  Eating at the Table of Another: Metabolomics of Host/Parasite Interactions
For example, as Toxoplasma parasites differentiate into slow-growing bradyzoites, they become increasingly resistant to many ... Host-parasite interactions revealed by Plasmodium falciparum metabolomics. Cell. Host Microbe. 2009;5:191-199. [PMC free ... Eating at the Table of Another: Metabolomics of Host/Parasite Interactions. Björn F.C. Kafsack1 and Manuel Llinás1,2,* ... It takes two to tango: Metabolomics of host/parasite systems By its very nature, parasite metabolism cannot be understood ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2825149/?lang=en-ca
*  Peter Bradley, Ph.D. - Department of Microbiology, Immunology and Molecular Genetics
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. ... creation of the parasitophorous vacuole in which the parasite resides, and host-parasite interaction. We have developed a ... establishing a new role for the rhoptries in host-parasite interaction. Given that these proteins are present in organelles ... Apicomplexans enter host cells by the active process of invasion that is driven by the parasite's actin-myosin motor and ...
  http://www.mimg.ucla.edu/people/peter-bradley-ph-d/
*  dict.md | Rab11A-Controlled Assembly of the Inner Membrane Complex Is Required for Completion of Apicomplexan Cytokinesis
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. ... Parasites were treated with Shld-1 after invasion of the host cell (+) or left untreated (−). 16 hours post invasion, parasites ... Parasites expressing ddFKBPRab11A(N126I) were inoculated on host cells (HFF). After invasion, intracellular parasites were ... Rab11A is essential for parasite development within host cells. Our ability to generate GFP-Rab11A transgenic parasites by ...
  http://www.dict.md/publication/rab11a-controlled-assembly-of-the-inner-membrane-complex-is-required-for-completion-of-apicomplexan-cytokinesis
*  Faculty Details | Department of Microbiology and Molecular Genetics
Cell Biology of Host-Parasite Interaction. Nearly one third of the world's population is infected with Toxoplasma gondii. ... AMA1 directly mediates the physical interaction between the parasite and host cell: remarkably, the extracellular domain of ... Motility Parasite motility is important for parasite movement into and out of host cells, for crossing biological barriers and ... T. gondii can only multiply within cells of its host, and repeated cycles of host cell invasion, parasite multiplication and ...
  http://www.uvm.edu/microbiology/directory/mmg-faculty-directory/faculty-details/?people_id=112
*  NON-HUMAN MAMMALS WITH T OR B CELLS HAVING PREDEFINED SPECIFICITY - Patent application
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J ... 0093] Toxoplasma gondii is an obligate intracellular parasite infecting all homeothermic vertebrate hosts, with human infection ... genetically engineered parasites to study immunity to Toxoplasma gondii. Parasite Immunol 2008; 30:235-44. [0175] 48. Zhou X W ... Parasites of interest include, e.g., Apicomplexans such as Toxoplasma, Cryptosporidium, or Plasmodium; kinetoplastids such as ...
  http://www.patentsencyclopedia.com/app/20110302665
*  Evaluation of immuno-efficacy of a novel DNA vaccine encoding Toxoplasma gondiirhoptry protein 38 (TgROP38) against chronic...
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J ... The obligate intracellular protozoa parasite Toxoplasma gondii can infect virtually all warm-blooded hosts including wild ... Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses. Cell Host Microbe ... Toxoplasma gondii is an obligate intracellular parasite which can infect almost all mammalian animals, leading to toxoplasmosis ...
  https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-14-525
*  Publications | the Department of Immunobiology
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions.', Nat Methods, vol. 7, issue 4, pp. 307-9, ... Blader, I. J., and A. A. Koshy, 'Toxoplasma gondii development of its replicative niche: in its host cell and beyond.', ... Toxoplasma co-opts host cells it does not invade.', PLoS Pathog, vol. 8, issue 7, pp. e1002825, 2012. PMCID: PMC3406079 PMID: ... Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii.', PLoS ...
  http://immunobiology.arizona.edu/research/koshy-lab/publications
*  Impact of protozoan cell death on parasite-host interactions and pathogenesis | Parasites & Vectors | Full Text
Wang Y, Weiss LM, Orlofsky A: Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth. J Biol ... and we hypothesize that it critically affects the parasite-host interaction by facilitating a sustained parasite-host ... Regarding the parasite-host interaction, several parasites are able to dampen immune responses and colonize the different ... In contrast, the impact of parasite necrosis for parasite-host interactions and whether it can occur in a regulated fashion as ...
  https://parasitesandvectors.biomedcentral.com/articles/10.1186/1756-3305-3-116
*  The Toxoplasma Blog: September 2014
Based on these properties it is clear that they are at the forefront of host-parasite interactions. In this review I compare ... a class XIVa myosin from the parasite Toxoplasma gondii, is required for the parasite to efficiently move and invade host cells ... The obligate intracellular parasite Toxoplasma gondii establishes a life-long chronic infection within any warm-blooded host. ... Large, rapidly evolving gene families are at the forefront of host-parasite interactions in Apicomplexa ...
  http://toxoplasmaparasite.blogspot.com/2014/09/
*  Systems Analysis Points to Links Between Toxoplasma Infection and Common Brain Diseases | Infection Control Today
... have a lifelong infection with the brain-dwelling parasite Toxoplasma gondii. In the Sept. 13, 2017, issue of Scientific ... Reports, 32 researchers from 16 institutions describe efforts to learn how infection with this parasite may alter, and in some ... the neural chemistry of the human host, and the multiple pathways that are perturbed by host-parasite interactions. ... But it benefits cats, who gain a meal, as well as the parasites, who gain a new host, who will distribute them widely into the ...
  http://www.infectioncontroltoday.com/infectious-diseases-conditions/systems-analysis-points-links-between-toxoplasma-infection-and-common
*  The Toxoplasma Blog: November 2009
GRA Proteins of Toxoplasma gondii: Maintenance of Host-Parasite Interactions across the Parasitophorous Vacuolar Membrane ... GRA Proteins of Toxoplasma gondii: Maintenance of Host-Parasite Interactions across the Parasitophorous Vacuolar Membrane. Nam ... Toxoplasma gondii is an intracellular pathogen notable for its ability to establish a stable host-parasite relationship amongst ... Unlike bacteria and viruses, Toxoplasma gondii and other parasites of the phylum Apicomplexa actively invade host cells and ...
  http://toxoplasmaparasite.blogspot.com/2009/11/
*  Identification, characterization and antigenicity of the Plasmodium vivax rhoptry neck protein 1 (Pv RON1) | Malaria Journal |...
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J ... It has been demonstrated that antibodies directed against antigenic proteins can inhibit parasite-host interaction [21] and, ... Ossorio PN, Schwartzman JD, Boothroyd JC: A Toxoplasma gondii rhoptry protein associated with host cell penetration has unusual ... DRM proteins have been shown to play an active role in host cell interaction and to trigger antibody responses in the host [11- ...
  https://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-10-314
*  Fresno State Bulletin Board • View topic - Biology Colloquium - Dr. Kirk Jensen
Our lab studies host-pathogen interactions using the widespread parasite of mammals and birds, Toxoplasma gondii. It is a very ... By studying this particular host-parasite interaction, insights might be gained to better activate these cells during an ... clever parasite, and is able to achieve chronic infection in the brains of most hosts, including 2 billion humans. Toxoplasma ... "Toxoplasma gondii - a parasite's understanding of the adaptive immune system". Friday, October 7, 2016. 3:00 PM. Science 2, ...
  https://www.fresnostate.edu/bulletinboard/viewtopic.php?f=9&t=3740&p=3729
*  The Toxoplasma Blog: March 2010
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions. Koshy AA, Fouts AE, Lodoen MB, Alkan O, Blau ... The invasion of host cells by Toxoplasma gondii is accompanied by a reorganization of host cell structure, in which the host ... Toxoplasma gondii is a parasite of birds and mammals. Cats are the only definitive host and thus the only source of infective ... This Toxoplasma strain efficiently injects a Cre fusion protein into host cells. In a Cre-reporter cell line, a single parasite ...
  http://toxoplasmaparasite.blogspot.com/2010/03/
*  Penn Vet | Pathobiology Faculty
Research Areas Infectious Disease, Toxoplasma gondii, Zoonotic diseases, Host-pathogen interactions, Immunology, Parasites, ... Research Areas Host-pathogen interactions Leishmania, Memory T cells, Immunology, Infectious Disease, Leishmaniasis, Parasites ... Research Areas Host-pathogen interactions, Vector biology, Malaria, Complement, Innate immunity ENRICO RADAELLI. *Associate ... Virus-host interaction, Innate immunity, Inflammatory responses, Respiratory ...
  https://www.vet.upenn.edu/research/academic-departments/pathobiology/pathobiology-faculty
*  The Toxoplasma Blog: Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans
This specific role of calcineurin in coordinating physical interactions with host cells highlights an ancestral mechanism for ... also contributes to host cell invasion by the malaria parasite Plasmodium falciparum and related Toxoplasma gondii. Using ... The Toxoplasma Blog features the latest news regarding this protozoan parasite, including information about relevant scientific ... Up to date information and news regarding the protozoan parasite Toxoplasma gondii ...
  http://toxoplasmaparasite.blogspot.com/2015/06/parasite-calcineurin-regulates-host.html
*  Interaction between the C-terminal region of TUBB2C and | Open-i
Interaction between the C-terminal region of TUBB2C and TgRON4 in T. gondii-infected CHO cells.(a) Upper: Schematic ... Host-Parasite Interactions/physiology*. *Peptide Hydrolases/metabolism*. *Protozoan Proteins/metabolism*. *Toxoplasma/ ... Our results provide evidence for a parasite-specific interaction between TgRON4 and the host cell cytoskeleton in parasite- ... Our results provide evidence for a parasite-specific interaction between TgRON4 and the host cell cytoskeleton in parasite- ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3824165_srep03199-f5&req=4
*  Editors for Microbiology and Infectious Disease | About | eLife
... in both pathogenic and commensal interactions, including but not limited to investigations into the microbiome, microbial ... We also welcome studies of all types of interactions between microorganisms in communities and between microbes and ... host-parasite interactions. apicomplexa biology. motility. Experimental organism. toxoplasma gondii. plasmodium. * Wesley ... host-microbiota interactions. microbiome. mucosal immunology. Competing interests statement. Wendy Garrett receives funding ...
  https://elifesciences.org/about/people/microbiology-infectious-disease
*  The Toxoplasma Blog: March 2017
Here we describe the pathways of host-parasite interaction at the parasitophorous vacuole employed by Toxoplasma and host, ... Toxoplasma gondii is a single-celled parasite that persists in its host as a transmissible tissue cyst. How the parasite ... Host cells; Microneme proteins; Protein-carbohydrate interactions; Protein-protein interactions; Toxoplasma gondii ... Metabolism; apicomplexan genomics; genomics of apicomplexan parasites; host cell modulation; host invasion; parasite genomics; ...
  http://toxoplasmaparasite.blogspot.com/2017/03/
*  The Toxoplasma Blog: April 2011
... caninum and Toxoplasma gondii is important in the exploration to determine the common mechanisms of parasite-host interaction ... Abstract All hosts, including humans, can be infected by any one of the three forms of the parasite Toxoplasma gondii that ... As an obligate intracellular parasite, Toxoplasma must alter the environment of its host cell in order to establish its ... Serum Response Factor Regulates Immediate Early Host Gene Expression in Toxoplasma gondii-Infected Host Cells. Wiley M, Teygong ...
  http://toxoplasmaparasite.blogspot.com/2011_04_01_archive.html