*  British Library EThOS: A comparison of host-parasite interactions between Toxoplasma gondii and Neospora caninum
A comparison of host-parasite interactions between Toxoplasma gondii and Neospora caninum ... To fully understand these biological differences, the host-parasite interactions of these parasites have been investigated in ... TgGRA2 was successfully purified by HPLC and attempts have been made to study its role in host-parasite interactions using a ... Due to the importance of protein-protein interactions (PPIs) and multiple protein complexes (MPCs) in host-parasite ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677498
*  Rhoptry - Wikipedia
"Proteomic Analysis of Rhoptry Organelles Reveals Many Novel Constituents for Host-Parasite Interactions in Toxoplasma gondii". ... The proteins they contain are important in the interaction between the host and the parasite. Rigoulet, Jacques; Hennache, ... Parasite. 21: 62. doi:10.1051/parasite/2014062. ISSN 1776-1042. PMC 4236686 . PMID 25407506. Bradley, Peter J; Chris Ward; ... They are club-shaped organelles connected by thin necks to the extreme apical pole of the parasite. These organelles, like ...
  https://en.wikipedia.org/wiki/Rhoptry
*  ApiLoc
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii.. ... These obligate intracellular parasites comprise some of the most important parasites of humans and animals, including the ... and proteases that are likely to play a key role in the ability of the parasite to invade and co-opt the host cell for its own ... Species: Toxoplasma gondii. *Quote inferring localisation: "Staining for ROP15 appears to extend into the rhoptry necks at the ...
  http://apiloc.biochem.unimelb.edu.au/apiloc/apiloc/publication/16002398
*  Eating at the Table of Another: Metabolomics of Host/Parasite Interactions
For example, as Toxoplasma parasites differentiate into slow-growing bradyzoites, they become increasingly resistant to many ... Host-parasite interactions revealed by Plasmodium falciparum metabolomics. Cell. Host Microbe. 2009;5:191-199. [PMC free ... Eating at the Table of Another: Metabolomics of Host/Parasite Interactions. Björn F.C. Kafsack1 and Manuel Llinás1,2,* ... It takes two to tango: Metabolomics of host/parasite systems By its very nature, parasite metabolism cannot be understood ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2825149/?lang=en-ca
*  Evaluation of immuno-efficacy of a novel DNA vaccine encoding Toxoplasma gondiirhoptry protein 38 (TgROP38) against chronic...
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J ... The obligate intracellular protozoa parasite Toxoplasma gondii can infect virtually all warm-blooded hosts including wild ... Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses. Cell Host Microbe ... Toxoplasma gondii is an obligate intracellular parasite which can infect almost all mammalian animals, leading to toxoplasmosis ...
  https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-14-525
*  Faculty Details | Department of Microbiology and Molecular Genetics
Cell Biology of Host-Parasite Interaction. Nearly one third of the world's population is infected with Toxoplasma gondii. ... AMA1 directly mediates the physical interaction between the parasite and host cell: remarkably, the extracellular domain of ... Motility Parasite motility is important for parasite movement into and out of host cells, for crossing biological barriers and ... T. gondii can only multiply within cells of its host, and repeated cycles of host cell invasion, parasite multiplication and ...
  http://www.uvm.edu/microbiology/directory/mmg-faculty-directory/faculty-details/?people_id=112
*  Publications | the Department of Immunobiology
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions.', Nat Methods, vol. 7, issue 4, pp. 307-9, ... Blader, I. J., and A. A. Koshy, 'Toxoplasma gondii development of its replicative niche: in its host cell and beyond.', ... Toxoplasma co-opts host cells it does not invade.', PLoS Pathog, vol. 8, issue 7, pp. e1002825, 2012. PMCID: PMC3406079 PMID: ... Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii.', PLoS ...
  http://immunobiology.arizona.edu/research/koshy-lab/publications
*  Impact of protozoan cell death on parasite-host interactions and pathogenesis | Parasites & Vectors | Full Text
Wang Y, Weiss LM, Orlofsky A: Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth. J Biol ... and we hypothesize that it critically affects the parasite-host interaction by facilitating a sustained parasite-host ... Regarding the parasite-host interaction, several parasites are able to dampen immune responses and colonize the different ... In contrast, the impact of parasite necrosis for parasite-host interactions and whether it can occur in a regulated fashion as ...
  https://parasitesandvectors.biomedcentral.com/articles/10.1186/1756-3305-3-116
*  The Toxoplasma Blog: September 2014
Based on these properties it is clear that they are at the forefront of host-parasite interactions. In this review I compare ... a class XIVa myosin from the parasite Toxoplasma gondii, is required for the parasite to efficiently move and invade host cells ... The obligate intracellular parasite Toxoplasma gondii establishes a life-long chronic infection within any warm-blooded host. ... Large, rapidly evolving gene families are at the forefront of host-parasite interactions in Apicomplexa ...
  http://toxoplasmaparasite.blogspot.com/2014/09/
*  Systems Analysis Points to Links Between Toxoplasma Infection and Common Brain Diseases | Infection Control Today
... have a lifelong infection with the brain-dwelling parasite Toxoplasma gondii. In the Sept. 13, 2017, issue of Scientific ... Reports, 32 researchers from 16 institutions describe efforts to learn how infection with this parasite may alter, and in some ... the neural chemistry of the human host, and the multiple pathways that are perturbed by host-parasite interactions. ... But it benefits cats, who gain a meal, as well as the parasites, who gain a new host, who will distribute them widely into the ...
  http://www.infectioncontroltoday.com/infectious-diseases-conditions/systems-analysis-points-links-between-toxoplasma-infection-and-common
*  The Toxoplasma Blog: November 2009
GRA Proteins of Toxoplasma gondii: Maintenance of Host-Parasite Interactions across the Parasitophorous Vacuolar Membrane ... GRA Proteins of Toxoplasma gondii: Maintenance of Host-Parasite Interactions across the Parasitophorous Vacuolar Membrane. Nam ... Toxoplasma gondii is an intracellular pathogen notable for its ability to establish a stable host-parasite relationship amongst ... Unlike bacteria and viruses, Toxoplasma gondii and other parasites of the phylum Apicomplexa actively invade host cells and ...
  http://toxoplasmaparasite.blogspot.com/2009/11/
*  Identification, characterization and antigenicity of the Plasmodium vivax rhoptry neck protein 1 (Pv RON1) | Malaria Journal |...
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J ... It has been demonstrated that antibodies directed against antigenic proteins can inhibit parasite-host interaction [21] and, ... Ossorio PN, Schwartzman JD, Boothroyd JC: A Toxoplasma gondii rhoptry protein associated with host cell penetration has unusual ... DRM proteins have been shown to play an active role in host cell interaction and to trigger antibody responses in the host [11- ...
  https://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-10-314
*  Fresno State Bulletin Board • View topic - Biology Colloquium - Dr. Kirk Jensen
Our lab studies host-pathogen interactions using the widespread parasite of mammals and birds, Toxoplasma gondii. It is a very ... By studying this particular host-parasite interaction, insights might be gained to better activate these cells during an ... clever parasite, and is able to achieve chronic infection in the brains of most hosts, including 2 billion humans. Toxoplasma ... "Toxoplasma gondii - a parasite's understanding of the adaptive immune system". Friday, October 7, 2016. 3:00 PM. Science 2, ...
  https://www.fresnostate.edu/bulletinboard/viewtopic.php?f=9&t=3740&p=3729
*  Penn Vet | Pathobiology Faculty
Research Areas Infectious Disease, Toxoplasma gondii, Zoonotic diseases, Host-pathogen interactions, Immunology, Parasites, ... Research Areas Host-pathogen interactions Leishmania, Memory T cells, Immunology, Infectious Disease, Leishmaniasis, Parasites ... Research Areas Host-pathogen interactions, Vector biology, Malaria, Complement, Innate immunity ENRICO RADAELLI. *Associate ... Virus-host interaction, Innate immunity, Inflammatory responses, Respiratory ...
  https://www.vet.upenn.edu/research/academic-departments/pathobiology/pathobiology-faculty
*  The Toxoplasma Blog: Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans
This specific role of calcineurin in coordinating physical interactions with host cells highlights an ancestral mechanism for ... also contributes to host cell invasion by the malaria parasite Plasmodium falciparum and related Toxoplasma gondii. Using ... The Toxoplasma Blog features the latest news regarding this protozoan parasite, including information about relevant scientific ... Up to date information and news regarding the protozoan parasite Toxoplasma gondii ...
  http://toxoplasmaparasite.blogspot.com/2015/06/parasite-calcineurin-regulates-host.html
*  Editors for Microbiology and Infectious Disease | About | eLife
... in both pathogenic and commensal interactions, including but not limited to investigations into the microbiome, microbial ... We also welcome studies of all types of interactions between microorganisms in communities and between microbes and ... host-parasite interactions. apicomplexa biology. motility. Experimental organism. toxoplasma gondii. plasmodium. * Wesley ... host-microbiota interactions. microbiome. mucosal immunology. Competing interests statement. Wendy Garrett receives funding ...
  https://elifesciences.org/about/people/microbiology-infectious-disease
*  The Toxoplasma Blog: March 2017
Here we describe the pathways of host-parasite interaction at the parasitophorous vacuole employed by Toxoplasma and host, ... Toxoplasma gondii is a single-celled parasite that persists in its host as a transmissible tissue cyst. How the parasite ... Host cells; Microneme proteins; Protein-carbohydrate interactions; Protein-protein interactions; Toxoplasma gondii ... Metabolism; apicomplexan genomics; genomics of apicomplexan parasites; host cell modulation; host invasion; parasite genomics; ...
  http://toxoplasmaparasite.blogspot.com/2017/03/
*  The Toxoplasma Blog: April 2011
... caninum and Toxoplasma gondii is important in the exploration to determine the common mechanisms of parasite-host interaction ... Abstract All hosts, including humans, can be infected by any one of the three forms of the parasite Toxoplasma gondii that ... As an obligate intracellular parasite, Toxoplasma must alter the environment of its host cell in order to establish its ... Serum Response Factor Regulates Immediate Early Host Gene Expression in Toxoplasma gondii-Infected Host Cells. Wiley M, Teygong ...
  http://toxoplasmaparasite.blogspot.com/2011_04_01_archive.html
*  DSpace@MIT: Browsing Department of Biology by Title
... little is known about the co-evolution of eukaryotic pathogens with their hosts. The intracellular parasite Toxoplasma ... ... Co-evolution of pathogen and host helps drive biological diversity. Unlike viral-host interactions, ... Evasion of interferon-gamma responses by Toxoplasma gondii in murine and human fibroblasts  ...
  http://dspace.mit.edu/handle/1721.1/7761/browse?order=ASC&rpp=20&sort_by=1&etal=-1&offset=237&type=title
*  Apicomplexa
Toxoplasma gondii: The role of parasite surface and secreted proteins in host cell invasion. International Journal for ... Attachment to the host cell is initiated via interaction of its surface proteins to the host cell's plasma membrane, an example ... Host-cell invasion by malaria parasites: insights from Plasmodium and Toxoplasma. Trends in Parasitology, 24, 557-563. ... Invasion of Host Cells. Invasion of host cells by apicomplexan parasites is highly conserved between related protozoa, with the ...
  http://www.tolweb.org/Apicomplexa
*  Host Defenses to Intracellular Pathogens | SpringerLink
... and is an important one in the contemporary area of how the host interacts with micro- organisms. ... Macrophage Oxygen-Dependent Killing of Intracellular Parasites: Toxoplasma and Leishmania Henry W. Murray ... Interaction of Mycobacteria with Normal and Immunologically Activated Alveolar Macrophages Quentin N. Myrvik, Eva S. Leake, ... Immunity to Rickettsia, Parasites and Fungi. * Activation of Macrophages for Killing of Rickettsiae: Analysis of Macrophage ...
  https://link.springer.com/book/10.1007%2F978-1-4684-4481-0
*  Specific phosphorylation of the PfRh2b invasion ligand of Plasmodium falciparum | Biochemical Journal
2008) Host-cell invasion by malaria parasites: insights from Plasmodium and Toxoplasma. Trends Parasitol. 24:557-563. ... and complex process that relies on an orchestrated cascade of interactions between the invading parasite and host cells [5]. ... In Toxoplasma gondii, another apicomplexan parasite, host-cell invasion can be blocked by the inhibition of CK2 (casein kinase ... synchronized Rh2b-HA parasites were harvested in the late schizont stage and the parasites were released from the host cells ...
  http://www.biochemj.org/content/452/3/457.long
*  UC Irvine - Faculty Profile System
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions. Nature Methods 7:307-9. 2010. ... Toxoplasma gondii dissemination: a parasite's journey through the infected host. Parasite Immunol. 37:141-9. 2015. ... Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15. mBio 4(4). 2013. ... A remarkable feature of T. gondii infection is the ability of the parasite to disseminate broadly in the infected host and to ...
  https://www.faculty.uci.edu/profile.cfm?faculty_id=5776
*  The Toxoplasma Blog: Plasticity and redundancy among AMA-RON pairs ensure host cell entry of Toxoplasma parasites
The composition and the assembly of the MJ, and in particular the presence of protein AMA1 and its interaction with protein ... Plasticity and redundancy among AMA-RON pairs ensure host cell entry of Toxoplasma parasites. Lamarque MH1, Roques M1, Kong-Hap ... Plasticity and redundancy among AMA-RON pairs ensure host cell entry of Toxoplasma parasites ... that anchors the parasite to the host cell and forms a ring through which the parasite penetrates. ...
  http://toxoplasmaparasite.blogspot.com/2014/06/plasticity-and-redundancy-among-ama-ron.html
*  cardiovascular physiologic phenomena
Parasite/Host Interactions and the Neurobiology of Fear. Robert Sapolsky; Fiscal Year: 2006 ... In Specific Aim 3, we will examine the effects of Toxoplasma infection on cell number and volume, and on dendritic morphology ... ANGII NEURAL INTERACTIONS IN CARDIOVASCULAR CONTROL. JOHN COLLISTER; Fiscal Year: 2002. ..Upon completion, Dr. Collister will ... Trigeminal Autonomic Interactions. Paul McCulloch; Fiscal Year: 2002. ..Having a better understanding of brainstem ...
  https://www.labome.org/topics/physical/natural/biological/circulatory/cardiovascular/cardiovascular-physiologic-phenomena-19998.html