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*  Pancytopenia - Wikipedia
Myelodysplastic-cytosis) Chronic radiation sickness LIG4 syndrome The disease is marked by an inappropriate and ineffective T ... thrombocytopenia: platelet count < 150×109/L. Treat the underlying cause Blood transfusion (PRBC) according to need Kossenko MM ... Familial hemophagocytic syndrome Aplastic anemia Gaucher's disease metastatic carcinoma of bone Multiple Myeloma overwhelming ... Such finding is common in the syndrome, which is also referred to as hemophagocytic lymphohistiocytosis (HLH). Along with ...
  https://en.wikipedia.org/wiki/Pancytopenia
*  Prognostic impact of severe thrombocytopenia in low-risk myelodysplastic syndrome.
METHODS: The authors analyzed the incidence and prognostic significance of thrombocytopenia at dia ... Thrombocytopenia is very common in myelodysplastic syndrome (MDS); however, its clinical impact in low-risk patients remains ... BACKGROUND: Thrombocytopenia is very common in myelodysplastic syndrome (MDS); however, its clinical impact in low-risk ... RESULTS: Thrombocytopenia (platelet count ,100 × 10(9) /L) was identified in 842 patients (32.8%). Severe thrombocytopenia ( ...
  http://www.biomedsearch.com/nih/Prognostic-impact-severe-thrombocytopenia-in/21638279.html
*  Eltrombopag in Myelodysplastic Syndrome (MDS) Patients With Thrombocytopenia - No Study Results Posted - ClinicalTrials.gov
Eltrombopag in Myelodysplastic Syndrome (MDS) Patients With Thrombocytopenia. The safety and scientific validity of this study ...
  https://clinicaltrials.gov/ct2/show/results/NCT01286038
*  Efficacy of Eltrombopag in Patients With Lower-Risk Myelodysplastic Syndromes and Thrombocytopenia - ASH Clinical News
Efficacy of Eltrombopag in Patients With Lower-Risk Myelodysplastic Syndromes and Thrombocytopenia - Literature Scan, News - ... Efficacy of Eltrombopag in Patients With Lower-Risk Myelodysplastic Syndromes and Thrombocytopenia. Saturday, April 1, 2017. ... Eltrombopag versus placebo for low-risk myelodysplastic syndromes with thrombocytopenia (EQoL-MDS): phase 1 results of a single ... Platelet transfusions are commonly administered to patients with myelodysplastic syndromes (MDS) who develop profound ...
  https://www.ashclinicalnews.org/news/efficacy-eltrombopag-patients-lower-risk-myelodysplastic-syndromes-thrombocytopenia/
*  A Single Arm Pilot Study of Azacitidine in Myelodysplastic Syndromes (MDS) / Acute Myeloid Leukaemia (AML), With Eltrombopag...
Syndrome. Leukemia. Leukemia, Myeloid. Leukemia, Myeloid, Acute. Myelodysplastic Syndromes. Preleukemia. Thrombocytopenia. ... Myelodysplastic Syndrome (MDS) is a disease of the bone marrow characterized by anemia,neutropenia, and thrombocytopenia (low ... Myelodysplastic Syndromes (MDS) Acute Myeloid Leukaemia (AML) Drug: Azacitidine and eltrombopag Phase 2 ... MedlinePlus related topics: Acute Myeloid Leukemia Leukemia Myelodysplastic Syndromes Drug Information available for: ...
  https://clinicaltrials.gov/ct2/show/NCT01488565?term=Thrombocytopenia%3A+Clinical+Trials&rank=12
*  A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome ...
Syndrome. Myelodysplastic Syndromes. Preleukemia. Thrombocytopenia. Disease. Pathologic Processes. Bone Marrow Diseases. ... Myelodysplastic syndromes (MDS) are bone marrow disorders characterized by anemia, neutropenia, and thrombocytopenia (low red ... The incidence and impact of thrombocytopenia in myelodysplastic syndromes. Cancer. 2007 May 1;109(9):1705-14. Review. ... Megakaryocytic dysfunction in myelodysplastic syndromes and idiopathic thrombocytopenic purpura is in part due to different ...
  https://clinicaltrials.gov/ct2/show/NCT00961064?term=thrombocytopenia&recr=Open&fund=01&rank=2
*  Thrombopoietin Receptor Agonists: Characteristics, Adverse Effects, and Indications | SpringerLink
While the most commonly utilized first-line therapeutics for the treatment of immune thrombocytopenia (ITP) target the ... The incidence and impact of thrombocytopenia in myelodysplastic syndromes. Cancer. 2007;109:170-1714.CrossRefGoogle Scholar ... Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia. J Clin Oncol. ... including myelodysplastic syndrome and acute myelogenous leukemia, chemotherapy-induced thrombocytopenia, congenital ...
  https://link.springer.com/chapter/10.1007/978-3-319-68038-5_18
*  Cogle CR[au] - PubMed - NCBI
Two novel RUNX1 mutations in a patient with congenital thrombocytopenia that evolved into a high grade myelodysplastic syndrome ... CC-486 (oral azacitidine) in patients with myelodysplastic syndromes with pretreatment thrombocytopenia. ... Fishing for myelodysplastic syndromes finds uncaptured cases by state cancer registries: Need for more resources. ... The Incidence and Health Care Resource Burden of the Myelodysplastic Syndromes in Patients in Whom First-Line Hypomethylating ...
  https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Cogle+CR%5Bau%5D&dispmax=50
*  A Study of the Safety and Efficacy of MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus (MK-0431A-289) -...
Hematological disorder (such as aplastic anemia, thrombocytopenia, myeloproliferative or myelodysplastic syndromes). *Is ... Active neuropathy (such as nephrotic syndrome or glomerulonephritis). *Chronic myopathy, mitochondrial disorder or a ...
  https://clinicaltrials.gov/ct2/show/record/NCT01760447?term=%22Type+2+Diabetes%22&lup_s=09%2F09%2F2013&lup_d=14&show_rss=Y&sel_rss=mod14
*  A Study of the Safety and Efficacy of MK-1293 Compared to Lantus™ in Participants With Type 1 Diabetes Mellitus (T1DM) (MK-1293...
has a hematological disorder (such as aplastic anemia, myeloproliferative or myelodysplastic syndromes, thrombocytopenia) ... acute coronary syndrome, coronary artery intervention, stroke or transient ischemic neurological disorder ...
  https://clinicaltrials.gov/ct2/show/NCT02059161
*  Study to Assess Safety & Efficacy of Sitagliptin as Initial Oral Therapy for Treatment of Type 2 Diabetes Mellitus in Pediatric...
Clinically significant hematological disorder (such as aplastic anemia, thrombocytopenia, myeloproliferative or myelodysplastic ... Known monogenic diabetes, secondary diabetes, or a genetic syndrome or disorder known to affect glucose tolerance other than ... Active nephropathy (i.e., nephrotic syndrome or glomerulonephritis).. *Chronic myopathy, mitochondrial disorder, or a ...
  https://clinicaltrials.gov/ct2/show/study/NCT01485614?term=%22Type+2+Diabetes%22&lup_s=10%2F03%2F2013&lup_d=14&show_rss=Y&sel_rss=mod14&show_locs=Y
*  Search | Aplastic Anemia and MDS International Foundation
Eltrombopag versus placebo for low-risk myelodysplastic syndromes with thrombocytopenia (EQoL-MDS): phase 1 results of a single ... and pharmacokinetics of subcutaneous azacitidine in Taiwanese patients with higher-risk myelodysplastic syndromes ... ... and severe thrombocytopenia. Patients with a stable platelet count of lower than 30 × 109 platelets per L, aged at least ... ... and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes ...
  http://www.aamds.org/search/node/platelet%20transfusion?destination=glossary/terms
*  Search | Page 4 | Aplastic Anemia and MDS International Foundation
Eltrombopag versus placebo for low-risk myelodysplastic syndromes with thrombocytopenia (EQoL-MDS): phase 1 results of a single ... Azacitidine in lower-risk myelodysplastic syndromes. ... 50% in lower-risk patients; most patients who achieved transfusion ... p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q) ... ... in patients with lower-risk myelodysplastic syndromes ... remission, red blood cell [RBC] or platelet transfusion independence ...
  http://www.aamds.org/search/node/transfusion%20independence?page=3
*  Obatoclax - Wikipedia
Study of Obatoclax Mesylate in Patients with Previously Untreated Myelodysplastic Syndromes with Anemia or Thrombocytopenia". ... myelodysplastic syndromes, Teva halted a phase III trial in patients with lung cancer before it had begun, citing "business ...
  https://en.wikipedia.org/wiki/Obatoclax
*  Copper deficiency - Wikipedia
The peripheral blood and bone marrow aspirate findings in copper deficiency can mimic myelodysplastic syndrome. Bone marrow ... Thrombocytopenia (low blood platelets) is unusual. ... Unlike most cases of myelodysplastic syndrome, the bone marrow ... and karyotyping in cases of copper deficiency does not reveal cytogenetic features characteristic of myelodysplastic syndrome. ... Copper deficiency masquerading as subacute combined degeneration of the cord and myelodysplastic syndrome. ACNR: Advances in ...
  https://en.wikipedia.org/wiki/Copper_deficiency
*  Thrombocytopenia - Wikipedia
Vitamin B12 or folic acid deficiency Leukemia or myelodysplastic syndrome or aplastic anemia Decreased production of ... Congenital amegakaryocytic thrombocytopenia Thrombocytopenia absent radius syndrome Fanconi anemia Bernard-Soulier syndrome, ( ... Grey platelet syndrome Alport syndrome Wiskott-Aldrich syndrome Abnormally high rates of platelet destruction may be due to ... "What Is Thrombocytopenia? - NHLBI, NIH". www.nhlbi.nih.gov. Retrieved 2015-05-01. Bhatia, M.P.S. "B.E. Project on Platlet Count ...
  https://en.wikipedia.org/wiki/Thrombocytopenia
*  Hematologic disease - Wikipedia
Antiphospholipid syndrome Disorders of platelets Thrombocytopenia Glanzmann's thrombasthenia Wiskott-Aldrich syndrome ... Decreased numbers of cells Myelodysplastic syndrome Myelofibrosis Neutropenia (decrease in the number of neutrophils) ... syndrome (antiplatelet antibodies and hemolytic antibodies) Cold autoimmune hemolytic anemia Cold agglutinin disease Paroxysmal ... Heparin-induced thrombocytopenia (HIT) Myeloproliferative disorders (Increased numbers of cells) Polycythemia vera (increase in ...
  https://en.wikipedia.org/wiki/Hematologic_disease
*  Janus kinase inhibitor - Wikipedia
... myeloproliferative neoplasms and myelodysplastic syndrome. PF-04965842 against JAK1 for atopic dermatitis and moderate to ... "Oral Pacritinib Versus Best Available Therapy to Treat Myelofibrosis with Thrombocytopenia". ClinicalTrials.gov. Retrieved 16 ... Myelodysplastic Syndrome (MDS)". ClinicalTrials.gov. Retrieved 16 July 2016. "Clinical Trials with PF04965842". ClinicalTrials. ...
  https://en.wikipedia.org/wiki/Janus_kinase_inhibitor
*  Myelodysplastic syndrome - Wikipedia
... is required to diagnose a myelodysplastic syndrome, so differentiating MDS from anemia, thrombocytopenia, and leukopenia is ... Myelodysplastic syndrome at Curlie (based on DMOZ) Fenaux, P., et al. (2014). [1] Myelodysplastic syndromes: ESMO Clinical ... Myelodysplastic syndromes (MDS) are a group of cancers in which immature blood cells in the bone marrow do not mature and ... MDS - Myelodysplastic Syndromes Archived 2011-06-14 at the Wayback Machine. Cutler CS, Lee SJ, Greenberg P, Deeg HJ, Perez WS, ...
  https://en.wikipedia.org/wiki/Myelodysplastic_syndrome
*  Acute erythroid leukemia - Wikipedia
That is, AEL is often associated with other risk factors, like monosomal karyotypes and a history of myelodysplastic syndrome. ... Signs of thrombocytopenia are found in about half of people with AEL. The causes of AEL are unknown. Prior to a 2008 ... Prognosis is worse in elderly patients, those with a history of myelodysplastic syndrome, and in patients who had previously ... cases that evolved from myelodysplastic syndromes, myeloproliferative neoplasms, chemotherapy for other cancers or exposure to ...
  https://en.wikipedia.org/wiki/Acute_erythroid_leukemia