*  Thrombin generation after the abrupt cessation of intravenous unfractionated heparin among patients with acute coronary...
1994) Thrombin plays a key role in late platelet thrombus growth and/or stability. Effect of a specific thrombin inhibitor on ... 1994) Persistent thrombin generation in humans during specific thrombin inhibition with hirudin. Circulation 90:2671-2678. ... Thrombin generation was evident by 1 h and increased steadily over time. Thrombin generation was greatest with abrupt heparin ... Thrombin generation in acute coronary syndromes. In vivo, thrombin serves as both the primary stimulus for thrombosis and ...
  http://www.onlinejacc.org/content/34/4/1020
*  Thrombin - how to use it in the best way?: post #1
Thrombin,...but I would like to be sure to do the experiment well, so I am here to ask you again some questions. I am doing a ... Thrombin - how to use it in the best way? - posted in Protein and Proteomics: Hello everybody! I have read a lot of topics ... Also tagged with one or more of these keywords: gst, thrombin, thrombin elimination. Protocols and Techniques Forums → Protein ... I am thinking to use Thrombin to divide protX+bound proteins from the GST but.... 1. Does Thrombin work well if there are beads ...
  http://www.protocol-online.org/forums/topic/27409-thrombin-how-to-use-it-in-the-best-way/
*  Thrombin generation in different cohorts : Evaluation of the haemostatic potential
... endogenous thrombin potential (ETP, total thrombin concentration), peak (maximum thrombin concentration) and time to peak ( ... The total amount of thrombin generated was not related to diagnosis. The prolonged thrombin generation noted in controls and FV ... The great over-lap in thrombin generation between patients with and without recurrences though, makes the use of thrombin ... Additionally, we study the correlation between thrombin generation at the time of an acute VTE and thrombin generation measured ...
  http://liu.diva-portal.org/smash/record.jsf?pid=diva2:660831
*  Global Thrombin Sales Market Report 2017 : ReportsnReports
In this report, the global Thrombin market is valued at... ... 117 Pages Report] Check for Discount on Global Thrombin Sales ... Global Thrombin Sales Market Report 2017 Table of Contents. Global Thrombin Sales Market Report 2017. 1 Thrombin Market ... 4 China Thrombin (Volume, Value and Sales Price). 4.1 China Thrombin Sales and Value (2012-2017). 4.1.1 China Thrombin Sales ... 6 Japan Thrombin (Volume, Value and Sales Price). 6.1 Japan Thrombin Sales and Value (2012-2017). 6.1.1 Japan Thrombin Sales ...
  http://www.reportsnreports.com/reports/1141626-global-thrombin-sales-market-report-2017.html
*  Discovery and development of direct thrombin inhibitors - Wikipedia
Thrombin also has two exosites (1 and 2). Thrombin is a little different from other serine proteases as exosite 1 is anion- ... Thrombin is in the serine protease family. It has 3 binding domains in which thrombin-inhibition drugs bind to. Those proteases ... But heparin can also form a bridge between thrombin and fibrin which binds to exosite 1 which protects the thrombin from ... DTIs aren't dependent to cofactors like antithrombin to inhibit thrombin so they can both inhibit free/soluble thrombin as well ...
  https://en.wikipedia.org/wiki/Discovery_and_development_of_direct_thrombin_inhibitors
*  Direct Thrombin Inhibitor Anticoagulants - Pharmacology
Two drugs that are direct inhibitors of thrombin but that do not involve antithrombin III or vitamin K in their mechanism of ... Direct Thrombin Inhibitor Anticoagulants. Fri, 03 Mar 2017 , Pharmacology Two drugs that are direct inhibitors of thrombin but ... 1 complex with thrombin to inhibit its protease activity. Argatroban (Acova, Novastan), a synthetic analogue of arginine, ...
  https://www.alpfmedical.info/pharmacology/direct-thrombin-inhibitor-anticoagulants.html
*  Thrombin - Wikipedia
E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene. ... Thrombin is sold under the brand name Fibrimex for use as a binding agent for meat. The thrombin in Fibrimex derives from ... Thrombin interacts with thrombomodulin. As part of its activity in the coagulation cascade, thrombin also promotes platelet ... Due to its high proteolytic specificity, thrombin is a valuable biochemical tool. The thrombin cleavage site (Leu-Val-Pro-Arg- ...
  https://en.wikipedia.org/wiki/Thrombin
*  Antithrombin activity of an algal polysaccharide. - Semantic Scholar
... concentration-dependent inhibition of thrombin-induced platelet aggregation, (c) thrombin has hypotensive effect, which was ... dose-dependent inhibition of thrombin-induced thrombosis. All the above data suggest that our fucansulfate could be a heparin ... blunted and zeroed by our fucansulfate in a dose-dependent way, (d) when aortae are stimulated with thrombin, they become ... concentration-dependent inhibition of thromboplastin or cephalin-kaolin-induced thrombin generation from platelets, (b) ...
  https://www.semanticscholar.org/paper/Antithrombin-activity-of-an-algal-polysaccharide-Trento-Cattaneo/9ce16b8a7f200ec88c4ed39d189ed159fbc08d48
*  STA THROMBIN 10
Determination of the Thrombin Time by STA Analyzers. Freeze-dried human thrombin (1.5NIH units/mL) with calcium.,medicine, ... Determination of the Thrombin Time by STA Analyzers. Freeze-dried human thrombin (1.5NIH units/mL) with calcium. ...
  http://www.bio-medicine.org/medicine-products/STA-THROMBIN-10-20319-1/
*  Endogenous thrombin potential following hemostatic therapy with 4-factor prothrombin complex concentrate: a 7-day observational...
Parameters relating to thrombin generation, from emergency room (ER) admission until day 7. Endogenous thrombin potential was ... Each well was calibrated to a parallel well with a thrombin calibrator (Thrombin calibrator TS 20.0, Thrombinoscope BV). ... The following parameters were recorded: lag time, peak thrombin generation, time to peak, and endogenous thrombin potential ( ... and between thrombin potential and thrombin inhibition potential. This balance may have been impaired in the FC-PCC group, ...
  https://ccforum.biomedcentral.com/articles/10.1186/cc13982
*  JCI - Importance of factor Xa in determining the procoagulant activity of whole-blood clots.
The binding of thrombin to fibrin is thought to be an important mechanism by which thrombi exhibit procoagulant activity; ... This study was designed to determine whether clotting factors other than thrombin are bound to whole-blood clots and can ... Clot-associated Factor Xa activity was resistant to inhibition by anti-thrombin III, judging from the lack of inhibition of ... Clots formed in vitro from human blood exhibited minimal thrombin activity when incubated in plasma depleted of vitamin K- ...
  https://www.jci.org/articles/view/116404
*  Thrombin Inhibitors | Thrombin inhibitors are one type of anticoagulant medication
Thrombin Inhibitors. Thrombin inhibitors are one type of anticoagulant medication. Search. Main menu. Skip to primary content ...
  http://thrombininhibitors.com
*  Aniara Bovine Thrombin (6 x 21 NIH)
6 x 21 NIH Bovine Thrombin For in vitro use only. Recommended for all research protocols where a source of highly purified and ... 1 NIH corresponds to about 2.5 nkats using the thrombin chromogenic substrate BIOPHEN CS-01(38). ...
  http://www.aniara.com/mm5/merchant.mvc?Store_Code=ANIA&Screen=PROD&Category_Code=antiIIaandantiXaactivityassays&Product_Code=ABE102K
*  Thrombin removel His tag protein digestion - Protein and Proteomics - BioForum
After thrombin cutting of his - tagged protein , Iam unable to purify the protein from by using size exclusion chromatography . ... always showing the contamination of thrombin residuals as per sds page .i am using PBS buffer for throbin cutting . could you ... Thrombin removel His tag protein digestion - posted in Protein and Proteomics: ... Thrombin removel His tag protein digestion. Started by Srinivas Penumutchu, Aug 21 2011 07:30 AM ...
  http://www.protocol-online.org/forums/topic/22565-thrombin-removel-his-tag-protein-digestion/
*  Tissue Factor and PAR2 Signaling in the Tumor Microenvironment | Arteriosclerosis, Thrombosis, and Vascular Biology
Nierodzik ML, Karpatkin S. Thrombin induces tumor growth, metastasis, and angiogenesis: Evidence for a thrombin-regulated ... mice lost all thrombin signaling, excluding the compensatory upregulation of other thrombin receptors. A limited role for PAR1 ... TF-dependent coagulation generates thrombin and induces pleiotrophic cellular effects of thrombin on platelets through G ... Consistent with efficient thrombin blockade NAPc2 blocks metastasis, and NAPc2 may be thus effective in both the early and late ...
  http://atvb.ahajournals.org/content/29/12/1999
*  Willems1991 - Simulating thrombin generation
Simulations of the effect of hirudin indicate that factor V is predominantly activated by thrombin and not by factor Xa. The ... A simulation model for the production of thrombin in plasma is presented. Values of the reaction rate constants as determined ... The dependence of this threshold value on different negative feedback reactions, e.g. the inactivation of thrombin and factor ... in purified systems are used and the model is tested by comparison of simulations of factor Xa, factor Va and thrombin ...
  http://www.ebi.ac.uk/biomodels/MODEL1807240002
*  THROMBIN TIME
Home : For health professionals : Refer a patient : Laboratory Services : Test Table : THROMBIN TIME ... Heparin, Direct Thrombin Inhibitors (Lepirudin, Argatroban, Dabigatran, etc.), Fibrin/fibrinogen degradation products may cause ... prolongation of the Thrombin Time. Other interferences include: Hemoglobin (,500 mg/dL), Triglycerides (1,000 mg/dL), Bilirubin ...
  http://www.legacyhealth.org/for-health-professionals/refer-a-patient/laboratory-services/test-table/thrombin-time.aspx
*  thrombin cleavage
... stephen goodwin goodwin at BINAH.CC.BRANDEIS.EDU Thu Oct 10 06:42:16 EST 1996 *Previous message: Looking for ... Hi folks Does anyone know of any bead technology that exists that allows efficient removal of thrombin protease after cleavage ...
  http://www.bio.net/bionet/mm/dros/1996-October/002429.html
*  thrombin antibodies?
... Ding Ming ming at mbcrr.harvard.edu Fri Mar 24 12:35:13 EST 1995 *Previous message: MW of IgG? ... I would appreciate if you can tell me who produce the thrombin antibodies and what their telephone numbers. Thanks in advance. ...
  http://www.bio.net/bionet/mm/methods/1995-March/026418.html
*  Thrombin Sawai - Drugs.com
A list of US medications equivalent to Thrombin Sawai is available on the Drugs.com website. ... Thrombin Sawai is a medicine available in a number of countries worldwide. ... Thrombin Sawai may be available in the countries listed below.. Ingredient matches for Thrombin Sawai. Thrombin. Thrombin is ...
  https://www.drugs.com/international/thrombin-sawai.html
*  Recothrom (Thrombin (Topical)) Information - Drugs.com
Thrombin (Topical)). Includes indications, proper use, special instructions, precautions, and possible side effects. ... Thrombin-JMI Epistaxis Kit, Thrombin-JMI Pump Spray Kit, Thrombin-JMI Syringe Spray Kit ... Generic Name: Thrombin (Topical) (THROM bin, TOP i kal). Brand Name: Evithrom, Recothrom, Recothrom Spray Kit, Thrombi-Gel, ... If you have an allergy to thrombin or any other part of Recothrom (thrombin (topical)). ...
  https://www.drugs.com/cdi/recothrom-thrombin-topical.html
*  Direct thrombin inhibitor - Wikipedia
Direct thrombin inhibitor. Direct thrombin inhibitors (DTIs) are a class of medication that act as anticoagulants (delaying ... Thrombin demonstrates a high level of allosteric regulation.[2] Allosterism in thrombin is regulated by the exosites 1 and 2 ... This SbO4L shows allosteric inhibition of thrombin for fibrinogen, while providing a competitive inhibition of thrombin ... Di Nisio M, Middeldorp S, Büller H (2005). "Direct thrombin inhibitors". N Engl J Med. 353 (10): 1028-40. doi:10.1056/ ...
  https://en.m.wikipedia.org/wiki/Direct_thrombin_inhibitor