*  RCSB PDB - 1CA8: Thrombin inhibitors with rigid tripeptidyl aldehydes Macromolecules Report Page
... structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes ... Thrombin, subunit H Trypsin-like serine proteases B2. 1ca8B02. Mainly Beta Beta Barrel Thrombin, subunit H Trypsin-like serine ...
  http://www.rcsb.org/pdb/explore/macroMoleculeData.do?structureId=1CA8
*  A Study to Evaluate the Safety and Effectiveness of Different Doses of Chrysalin in Adults Who Have a Broken Wrist - Tabular...
Chrysalin, also known as TP508, is a synthetic peptide (protein) that is an exact copy of part of the human protein thrombin, ... Chrysalin can be used to mimic part of the thrombin response after injury without stimulating any of the events associated with ...
  https://clinicaltrials.gov/ct2/show/record/NCT00131482
*  A Phase 3b, Open-Label, Single-Group Immunogenicity and Safety Study of Topical Recombinant Thrombin (rThrombin) in Surgical...
This study investigated the efficacy and immunogenicity of thrombin alfa [rThrombin; ZymoGenetics] in patients with spinal and ... A Phase 3b, Open-Label, Single-Group Immunogenicity and Safety Study of Topical Recombinant Thrombin (rThrombin) in Surgical ... A Phase 3b, Open-Label, Single-Group Immunogenicity and Safety Study of Topical Recombinant Thrombin (rThrombin) in Surgical ...
  http://adisinsight.springer.com/trials/700245158?error=cookies_not_supported&code=f386f380-12f3-4d85-80e9-cb1dd1dc43b7
*  Thrombin generation in different cohorts : Evaluation of the haemostatic potential
... endogenous thrombin potential (ETP, total thrombin concentration), peak (maximum thrombin concentration) and time to peak ( ... The total amount of thrombin generated was not related to diagnosis. The prolonged thrombin generation noted in controls and FV ... The great over-lap in thrombin generation between patients with and without recurrences though, makes the use of thrombin ... Additionally, we study the correlation between thrombin generation at the time of an acute VTE and thrombin generation measured ...
  http://liu.diva-portal.org/smash/record.jsf?pid=diva2:660831
*  Global Thrombin Sales Market Report 2017 : ReportsnReports
In this report, the global Thrombin market is valued at... ... 117 Pages Report] Check for Discount on Global Thrombin Sales ... Global Thrombin Sales Market Report 2017 Table of Contents. Global Thrombin Sales Market Report 2017. 1 Thrombin Market ... 4 China Thrombin (Volume, Value and Sales Price). 4.1 China Thrombin Sales and Value (2012-2017). 4.1.1 China Thrombin Sales ... 6 Japan Thrombin (Volume, Value and Sales Price). 6.1 Japan Thrombin Sales and Value (2012-2017). 6.1.1 Japan Thrombin Sales ...
  http://www.reportsnreports.com/reports/1141626-global-thrombin-sales-market-report-2017.html
*  Direct Thrombin Inhibitor Anticoagulants - Pharmacology
Two drugs that are direct inhibitors of thrombin but that do not involve antithrombin III or vitamin K in their mechanism of ... Direct Thrombin Inhibitor Anticoagulants. Fri, 03 Mar 2017 , Pharmacology Two drugs that are direct inhibitors of thrombin but ... 1 complex with thrombin to inhibit its protease activity. Argatroban (Acova, Novastan), a synthetic analogue of arginine, ...
  https://www.alpfmedical.info/pharmacology/direct-thrombin-inhibitor-anticoagulants.html
*  Antithrombin activity of an algal polysaccharide. - Semantic Scholar
... concentration-dependent inhibition of thrombin-induced platelet aggregation, (c) thrombin has hypotensive effect, which was ... dose-dependent inhibition of thrombin-induced thrombosis. All the above data suggest that our fucansulfate could be a heparin ... blunted and zeroed by our fucansulfate in a dose-dependent way, (d) when aortae are stimulated with thrombin, they become ... concentration-dependent inhibition of thromboplastin or cephalin-kaolin-induced thrombin generation from platelets, (b) ...
  https://www.semanticscholar.org/paper/Antithrombin-activity-of-an-algal-polysaccharide-Trento-Cattaneo/9ce16b8a7f200ec88c4ed39d189ed159fbc08d48
*  STA THROMBIN 10
Determination of the Thrombin Time by STA Analyzers. Freeze-dried human thrombin (1.5NIH units/mL) with calcium.,medicine, ... Determination of the Thrombin Time by STA Analyzers. Freeze-dried human thrombin (1.5NIH units/mL) with calcium. ...
  http://www.bio-medicine.org/medicine-products/STA-THROMBIN-10-20319-1/
*  Endogenous thrombin potential following hemostatic therapy with 4-factor prothrombin complex concentrate: a 7-day observational...
Parameters relating to thrombin generation, from emergency room (ER) admission until day 7. Endogenous thrombin potential was ... Each well was calibrated to a parallel well with a thrombin calibrator (Thrombin calibrator TS 20.0, Thrombinoscope BV). ... The following parameters were recorded: lag time, peak thrombin generation, time to peak, and endogenous thrombin potential ( ... and between thrombin potential and thrombin inhibition potential. This balance may have been impaired in the FC-PCC group, ...
  https://ccforum.biomedcentral.com/articles/10.1186/cc13982
*  JCI - Importance of factor Xa in determining the procoagulant activity of whole-blood clots.
The binding of thrombin to fibrin is thought to be an important mechanism by which thrombi exhibit procoagulant activity; ... This study was designed to determine whether clotting factors other than thrombin are bound to whole-blood clots and can ... Clot-associated Factor Xa activity was resistant to inhibition by anti-thrombin III, judging from the lack of inhibition of ... Clots formed in vitro from human blood exhibited minimal thrombin activity when incubated in plasma depleted of vitamin K- ...
  https://www.jci.org/articles/view/116404
*  Structure Cluster - 1BA8: THROMBIN INHIBITOR WITH A RIGID TRIPEPTIDYL ALDEHYDES 3D Similarity Report Page
... structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes. ... Description: THROMBIN protein , Length: 36 No structure alignment results are available for 1BA8.A explicitly.. It is ... Description: THROMBIN protein , Length: 259 No structure alignment results are available for 1BA8.B explicitly.. It is ...
  http://www.rcsb.org/pdb/explore/structureCluster.do?structureId=1BA8
*  Thrombin removel His tag protein digestion - Protein and Proteomics - BioForum
After thrombin cutting of his - tagged protein , Iam unable to purify the protein from by using size exclusion chromatography . ... always showing the contamination of thrombin residuals as per sds page .i am using PBS buffer for throbin cutting . could you ... Thrombin removel His tag protein digestion - posted in Protein and Proteomics: ... Thrombin removel His tag protein digestion. Started by Srinivas Penumutchu, Aug 21 2011 07:30 AM ...
  http://www.protocol-online.org/forums/topic/22565-thrombin-removel-his-tag-protein-digestion/
*  Tissue Factor and PAR2 Signaling in the Tumor Microenvironment | Arteriosclerosis, Thrombosis, and Vascular Biology
Nierodzik ML, Karpatkin S. Thrombin induces tumor growth, metastasis, and angiogenesis: Evidence for a thrombin-regulated ... mice lost all thrombin signaling, excluding the compensatory upregulation of other thrombin receptors. A limited role for PAR1 ... TF-dependent coagulation generates thrombin and induces pleiotrophic cellular effects of thrombin on platelets through G ... Consistent with efficient thrombin blockade NAPc2 blocks metastasis, and NAPc2 may be thus effective in both the early and late ...
  http://atvb.ahajournals.org/content/29/12/1999
*  Thrombin - Wikipedia
E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene. ... Thrombin is sold under the brand name Fibrimex for use as a binding agent for meat. The thrombin in Fibrimex derives from ... Thrombin interacts with thrombomodulin. As part of its activity in the coagulation cascade, thrombin also promotes platelet ... Due to its high proteolytic specificity, thrombin is a valuable biochemical tool. The thrombin cleavage site (Leu-Val-Pro-Arg- ...
  https://en.wikipedia.org/wiki/Thrombin
*  THROMBIN TIME
Home : For health professionals : Refer a patient : Laboratory Services : Test Table : THROMBIN TIME ... Heparin, Direct Thrombin Inhibitors (Lepirudin, Argatroban, Dabigatran, etc.), Fibrin/fibrinogen degradation products may cause ... prolongation of the Thrombin Time. Other interferences include: Hemoglobin (,500 mg/dL), Triglycerides (1,000 mg/dL), Bilirubin ...
  http://www.legacyhealth.org/for-health-professionals/refer-a-patient/laboratory-services/test-table/thrombin-time.aspx
*  thrombin cleavage
... stephen goodwin goodwin at BINAH.CC.BRANDEIS.EDU Thu Oct 10 06:42:16 EST 1996 *Previous message: Looking for ... Hi folks Does anyone know of any bead technology that exists that allows efficient removal of thrombin protease after cleavage ...
  http://www.bio.net/bionet/mm/dros/1996-October/002429.html
*  thrombin antibodies?
... Ding Ming ming at mbcrr.harvard.edu Fri Mar 24 12:35:13 EST 1995 *Previous message: MW of IgG? ... I would appreciate if you can tell me who produce the thrombin antibodies and what their telephone numbers. Thanks in advance. ...
  http://www.bio.net/bionet/mm/methods/1995-March/026418.html
*  Thrombin Sawai - Drugs.com
A list of US medications equivalent to Thrombin Sawai is available on the Drugs.com website. ... Thrombin Sawai is a medicine available in a number of countries worldwide. ... Thrombin Sawai may be available in the countries listed below.. Ingredient matches for Thrombin Sawai. Thrombin. Thrombin is ...
  https://www.drugs.com/international/thrombin-sawai.html
*  Recothrom (Thrombin (Topical)) Information - Drugs.com
Thrombin (Topical)). Includes indications, proper use, special instructions, precautions, and possible side effects. ... Thrombin-JMI Epistaxis Kit, Thrombin-JMI Pump Spray Kit, Thrombin-JMI Syringe Spray Kit ... Generic Name: Thrombin (Topical) (THROM bin, TOP i kal). Brand Name: Evithrom, Recothrom, Recothrom Spray Kit, Thrombi-Gel, ... If you have an allergy to thrombin or any other part of Recothrom (thrombin (topical)). ...
  https://www.drugs.com/cdi/recothrom-thrombin-topical.html
*  Direct thrombin inhibitor - Wikipedia
Direct thrombin inhibitor. Direct thrombin inhibitors (DTIs) are a class of medication that act as anticoagulants (delaying ... Thrombin demonstrates a high level of allosteric regulation.[2] Allosterism in thrombin is regulated by the exosites 1 and 2 ... This SbO4L shows allosteric inhibition of thrombin for fibrinogen, while providing a competitive inhibition of thrombin ... Di Nisio M, Middeldorp S, B├╝ller H (2005). "Direct thrombin inhibitors". N Engl J Med. 353 (10): 1028-40. doi:10.1056/ ...
  https://en.m.wikipedia.org/wiki/Direct_thrombin_inhibitor
*  Discovery and development of direct thrombin inhibitors - Wikipedia
Thrombin also has two exosites (1 and 2). Thrombin is a little different from other serine proteases as exosite 1 is anion- ... Thrombin is in the serine protease family. It has 3 binding domains in which thrombin-inhibition drugs bind to. Those proteases ... But heparin can also form a bridge between thrombin and fibrin which binds to exosite 1 which protects the thrombin from ... DTIs aren't dependent to cofactors like antithrombin to inhibit thrombin so they can both inhibit free/soluble thrombin as well ...
  https://en.wikipedia.org/wiki/Discovery_and_development_of_direct_thrombin_inhibitors
*  Thrombin: Indications, Side Effects, Warnings - Drugs.com
Easy to read patient leaflet for Thrombin. Includes indications, proper use, special instructions, precautions, and possible ... What do I need to tell my doctor BEFORE I take Thrombin?. *If you have an allergy to thrombin or any other part of thrombin. ... Thrombin human, recombinant Topical application (Advanced Reading). Other brands: Recothrom, Thrombin-JMI, Thrombogen, Evithrom ... How do I store and/or throw out Thrombin?. *If you need to store thrombin at home, talk with your doctor, nurse, or pharmacist ...
  https://www.drugs.com/cdi/thrombin.html
*  Thrombin Inhibitors - MP Biomedicals
Bovine Albumin Bovine Transferrin CellMaxx Thrombin >> View All Bovine Proteins Food & Biodiesel Analysis. Platforms, Analyzers ... Bovine Albumin Bovine Transferrin CellMaxx Thrombin >> View All Bovine Proteins Empowered. Amino Acids and Enzymes Buffers and ...
  http://www.mpbio.com/index.php?cPath=1_5_26_165&country=223
*  Anti-Thrombin antibody (ab83981) Protocols | Abcam
Abcam provides specific protocols for Anti-Thrombin antibody (ab83981) : Immunohistochemistry protocols, Immunocytochemistry & ...
  http://www.abcam.com/thrombin-antibody-ab83981-protocols.html